High-Resolution Near-Infrared Imaging of the Powerful Radio Galaxy 3C 324 at z = 1.21 with the Subaru Telescope

We have obtained high-resolution K'-band images of the powerful z=1.206 radio galaxy 3C 324 with the Subaru telescope under seeing conditions of 0.3--0.4 arcsec. We clearly resolved the galaxy and directly compared it to the optical images obtained with the Hubble Space Telescope. The host galaxy of 3C 324 is revealed to be a moderately luminous elliptical galaxy with a smooth light profile. The effective radius of the galaxy, as determined by profile fitting, is 1.3+-0.1 arcsec (1.2 kpc), which is significantly smaller than the value of 2.2 arcsec, published in Best et al. (1998, MNRAS, 292, 758). The peak of the K'-band light coincides with the position of the radio core, which implies that the powerful AGN lies at the nucleus of the host galaxy. The peak also coincides with the gap in the optical knotty structures which may be a dust lane hiding the UV-optical emission of the AGN from our line of sight; it is very likely that we are seeing the obscuring structure almost edge-on. We clearly detected the `aligned component' in the K'-band image by subtracting a model elliptical galaxy from the observed image. The red R_F702W-K color of the outer region of the galaxy avoiding the aligned component indicates that the near infrared light of the host galaxy is dominated by an old stellar population.Comment: 21 pages (10 figures), accepted for publication in PAS

On-going frontal alpha rhythms are dominant in passive state and desynchronize in active state in adult gray mouse lemurs

The gray mouse lemur (Microcebus murinus) is considered a useful primate model for translational research. In the framework of IMI PharmaCog project (Grant Agreement n°115009, www.pharmacog.org), we tested the hypothesis that spectral electroencephalographic (EEG) markers of motor and locomotor activity in gray mouse lemurs reflect typical movement-related desynchronization of alpha rhythms (about 8-12 Hz) in humans. To this aim, EEG (bipolar electrodes in frontal cortex) and electromyographic (EMG; bipolar electrodes sutured in neck muscles) data were recorded in 13 male adult (about 3 years) lemurs. Artifact-free EEG segments during active state (gross movements, exploratory movements or locomotor activity) and awake passive state (no sleep) were selected on the basis of instrumental measures of animal behavior, and were used as an input for EEG power density analysis. Results showed a clear peak of EEG power density at alpha range (7-9 Hz) during passive state. During active state, there was a reduction in alpha power density (8-12 Hz) and an increase of power density at slow frequencies (1-4 Hz). Relative EMG activity was related to EEG power density at 2-4 Hz (positive correlation) and at 8-12 Hz (negative correlation). These results suggest for the first time that the primate gray mouse lemurs and humans may share basic neurophysiologic mechanisms of synchronization of frontal alpha rhythms in awake passive state and their desynchronization during motor and locomotor activity. These EEG markers may be an ideal experimental model for translational basic (motor science) and applied (pharmacological and non-pharmacological interventions) research in Neurophysiology

Cosmic shear statistics in the Suprime-Cam 2.1 sq deg field: Constraints on Omega_m and sigma_8

We present measurements of the cosmic shear correlation in the shapes of galaxies in the Suprime-Cam 2.1 deg^2 R_c-band imaging data. As an estimator of the shear correlation originated from the gravitational lensing, we adopt the aperture mass variance. We detect a non-zero E mode variance on scales between 2 and 40arcmin. We also detect a small but non-zero B mode variance on scales larger than 5arcmin. We compare the measured E mode variance to the model predictions in CDM cosmologies using maximum likelihood analysis. A four-dimensional space is explored, which examines sigma_8, Omega_m, Gamma and zs (a mean redshift of galaxies). We include three possible sources of error: statistical noise, the cosmic variance estimated using numerical experiments, and a residual systematic effect estimated from the B mode variance. We derive joint constraints on two parameters by marginalizing over the two remaining parameters. We obtain an upper limit of Gamma0.9 (68% confidence). For a prior Gamma\in[0.1,0.4] and zs\in[0.6,1.4], we find sigma_8=(0.50_{-0.16}^{+0.35})Omega_m^{-0.37} for flat cosmologies and sigma_8=(0.51_{-0.16}^{+0.29})Omega_m^{-0.34}$ for open cosmologies (95% confidence). If we take the currently popular LCDM model, we obtain a one-dimensional confidence interval on sigma_8 for the 95.4% level, 0.62<\sigma_8<1.32 for zs\in[0.6,1.4]. Information on the redshift distribution of galaxies is key to obtaining a correct cosmological constraint. An independent constraint on Gamma from other observations is useful to tighten the constraint.Comment: 12 pages, 12 figures, accepted for publication in Ap

Interest in a Mobile App for Two-Way Risk Communication: A Survey Study Among European Healthcare Professionals and Patients

INTRODUCTION: Previously, an app has been developed for healthcare professionals (HCPs) and patients to report adverse drug reactions (ADRs) to national medicines agencies and to receive drug safety information. OBJECTIVE: This study aimed to assess (1) European HCPs' and patients' interest in an app for this two-way risk communication; (2) their preferences and perceptions towards specific app characteristics; and (3) which HCPs and patients are particularly interested in the app. In addition, these aspects were studied specifically for the countries where such an app was already available, i.e. Croatia, The Netherlands, and The UK. METHODS: European HCPs and patients were asked to complete a web-based survey developed in the context of the Web-Recognizing Adverse Drug Reactions (Web-RADR) project. Data on app interest and preferences and perceptions towards app characteristics were analysed descriptively. Logistic regression analyses were conducted to assess the association of HCP characteristics and patient characteristics on the level of interest in the app (i.e. very interested vs. not/somewhat interested). RESULTS: In total, 399 HCPs and 656 patients completed the survey. About half of the patients (48%; ranging from 38% from The Netherlands to 54% from The UK), and 61% of the HCPs (ranging from 42% from The Netherlands to 54% from The UK) were very interested in the app. A faster means of reporting ADRs and easier access to the reporting form were the main perceived benefits. HCPs and patients who already use a health app were particularly interested in the app (HCPs: odds ratio [OR] 3.52; 95% confidence interval [CI] 1.96-6.30, patients: OR 1.64; 95% CI 1.19-2.27). CONCLUSIONS: An app is positively perceived by HCPs and patients for reporting ADRs quickly and for receiving drug safety information from national medicines agencies. In particular, HCPs and patients who already use other health apps were interested in the app

Pengaruh Dukungan Keluarga dan Motivasi Berwirausaha terhadap Kesejahteraan Keluarga dengan Kinerja Usaha Mompreneur sebagai Variabel Intervening

Tujuan penelitian ini adalah untuk menguji variabel kinerja usaha mompreneur sebagai mediasi dukungan keluarga dan motivasi berwirausaha terhadap kesejahteraan keluarga. Penelitian ini melibatkan 125 mompreneur yang diperoleh dengan cara menyebarkan kuesioner secara offline. Hasil yang diperoleh dianalisis menggunakan SPSS versi 26 dan kalkulator Sobel Test. Hasil menunjukkan bahwa dukungan keluarga dan motivasi berwirausaha berpengaruh positif terhadap kinerja usaha mompreneur dan kesejahteraan keluarga, selain itu kinerja usaha mompreneur juga memediasi pengaruh dukungan keluarga dan motivasi berwirausaha terhadap kesejahteraan keluarga. Penelitian ini memberikan implikasi teoritis bagi pengembangan teori kewirausahaan dengan menekankan pentingnya dukungan keluarga dan motivasi berwirausaha dalam meningkatkan kinerja usaha dan kesejahteraan keluarga. Implikasi praktisnya adalah perlunya program pelatihan kewirausahaan untuk meningkatkan motivasi dan kinerja usaha mompreneur.The purpose of this study is to examine the role of mompreneurs' business performance as a mediator between family support and entrepreneurial motivation on family welfare. This research involved 125 mompreneurs obtained by distributing offline questionnaires. The results were analyzed using SPSS version 26 and the Sobel Test calculator. The findings indicate that family support and entrepreneurial motivation have a positive influence on mompreneurs' business performance and family welfare. Additionally, mompreneurs' business performance mediates the influence of family support and entrepreneurial motivation on family welfare. This study provides theoretical implications for the development of entrepreneurship theory by emphasizing the importance of family support and entrepreneurial motivation in improving business performance and family welfare. The practical implication is the need for entrepreneurship training programs to enhance mompreneurs' motivation and business performance

STUDI KELAYAKAN KOLAM INTENSIF UDANG DENGAN MEMPERTAHANKAN KUALITAS AIR DI KELURAHAN KEPUTIH KOTA SURABAYA

Abstrak - keputih merupakan salah satu tempat di Surabaya tempat untuk budidaya ikan air tawar dengan menggunakan media tambak, salah satu jenisnya yaitu udang vaname. Membudidaya dengan menggunakan media tambak banyak memiliki kekurangan sehingga menggantikannya dengan kolam intesif diharapkan hasil panen yang didapat maksimal. Dalam melakukan pendirian suatu usaha, harus mempetimbangkan aspek aspek dalam pendirian. Pada aspek pasar permintaan efektif udang harus memiliki target pasar. Untuk aspek teknis dilakukan pendirian kebutuhan kolam dan gedung sesuai dengan pemintaan pasar dan aspek manajemen menentukan karyawan yang sesuai dari pekerjaan tersebut. Pada aspek keuangan nilai NPV sebesar Rp 13.275.693 dari nilai Total Project Cost (TPC) Rp 3.514.301.97 dengan horizon perencanaan 5 tahun membuat pendirian usaha kolam intensif udang layak untuk didirikan karena nilai NPV Rp 13.275.693 dan IRR sebesar 16,32% Kata kunci: kolam intensif, udang vaname, NPV, layak Abstract – keputih is one of the places in Surabaya where to cultivate freshwater fish by using pond media, one of its kind is shrimp vaname. Cultivation by using pond media has many shortcomings so that replacing it with intensive pond is expected to get maximum harvest result. In establishing a business, must consider aspects of aspect of establishment. In the market aspect the effective demand of shrimp must have a target market. For the technical aspects, the establishment of the needs of ponds and buildings in accordance with market demand and management aspects determine the appropriate employees of the work. In the financial aspect, the NPV value of Rp 13,275,693 from the Total Project Cost (TPC) value of Rp 3,514,301.97 with the 5-year planning horizon makes the establishment of shrimp pond intensive business feasible to be established because the value of NPV Rp 13.275.693 and IRR of 16.32% Keywords: intensive pool, vaname shrimp, NPV, decen

Characterising cerebral haemodynamic oscillations during running

Running involves repetitive foot-strikes that induces a ‘beat phenomenon’, identified as a summation of two pressure waves that result in periodic pulse pressure oscillations. To date, only one study has examined this phenomenon to investigate how it affects cerebral blood flow (CBF) responses, reporting that blood pressure oscillations are reflected in CBF (as indexed by middle cerebral artery blood velocity, MCAv). Based on this work, we tested the hypothesis that altering the heel-strike force would impact the amplitude, frequency and duration of MCAv oscillations. Ten participants completed four exercise sessions: a treadmill maximal oxygen consumption test (i.e. VO2peak), followed by a randomised crossover design of three submaximal exercise sessions: (i) gradient running protocol; (ii) step frequency and foot-strike running protocol, and (iii) 30-minute cycling 65% VO2peak protocol. Oscillations were present during each running protocol with a variety of oscillatory patterns occurring between participants and between different gradients, running styles and step frequencies. No statistical difference in the oscillatory pattern occurred between submaximal treadmill running protocols (p>.05), while no MCAv oscillations were present during cycling. Data collectively demonstrated that altering the heel-strike force during running affects the oscillatory pattern in MCAv, albeit not statistically supported from this small sample size