PERAN KOMUNIKASI INTERNAL TERHADAP EFEKTIVITAS KERJA DAN KINERJA KARYAWAN PADA DINAS KETAHANAN PANGAN PROVINSI JAMBI

This research aims to explore the role of internal communication on work effectiveness and employee performance at the Jambi Province Food Security Service. Internal communication is a key factor in increasing organizational efficiency and productivity, especially in the government context. The research approach used is qualitative with descriptive methods, aiming to understand the experiences, perceptions and dynamics of interactions between employees and management. Data was obtained through in-depth interviews with 3 participants consisting of structural officials and functional employees, as well as through direct observation of communication patterns in the work environment. The research results show that effective internal communication characterized by openness of information, active participation of all parties, and transparent two-way communication contributes significantly to increasing work effectiveness and employee performance. Employees who feel they have received sufficient information and are involved in decision making are more motivated and show better performance

Dua Dekade Setelah Peristiwa Traumatis: Prevalensi Kesehatan Mental Penyintas Tsunami Aceh

The long-term psychological impact of a traumatic natural disaster, such as the 2004 Aceh Tsunami, is still poorly documented in the scientific literature. The purpose of this study was to describe the mental health status of survivors of the 2004 Aceh Tsunami 20 years after the Aceh Tsunami, utilizing a descriptive quantitative research design. The study participants were 197 tsunami survivors selected by purposive sampling, with specific criteria: (1) being victims directly exposed to the 2004 Aceh Tsunami; and (2) being members of the Aceh community. The Mental Health Inventory-18 (MHI-18; α = .93) was utilized as the data collection instrument for mental health in this study. The results of the data analysis showed that the majority of survivors (78.17%) had low mental health or psychological well-being, reflecting ongoing psychological disorders even though 20 years had passed since the disaster. The findings of this study indicate that the psychological impact of the Aceh Tsunami continues in the long term, significantly affecting psychological well-being. The results of this study emphasize the need for special attention to the mental health of disaster survivors, as well as the importance of long-term support programs to mitigate the long-term psychological impacts post-disasters.Dampak psikologis jangka panjang dari bencana alam yang traumatis, seperti Tsunami Aceh 2004, masih belum banyak didokumentasikan dalam literatur ilmiah. Tujuan studi ini adalah mendeskripsikan status kesehatan mental para penyintas Tsunami Aceh 2004 pasca 20 tahun Tsunami Aceh dengan menggunakan desain penelitian kuantitatif deskriptif. Partisipan studi adalah 197 penyintas tsunami yang dipilih dengan purposive sampling, dengan kriteria khusus: (1) merupakan korban yang terpapar langsung bencana Tsunami Aceh 2004; dan (2) merupakan masyarakat Aceh. Mental Health Inventory-18 (MHI-18; α = 0,93) digunakan sebagai instrumen pengumpulan data untuk kesehatan mental dalam studi ini. Hasil analisis data menunjukkan bahwa mayoritas penyintas (78,17%) memiliki status kesehatan mental atau kesejahteraan psikologis yang rendah, mencerminkan adanya gangguan psikologis yang masih berlangsung meskipun 20 tahun telah berlalu sejak bencana tersebut. Temuan studi ini mengindikasikan bahwa dampak psikologis Tsunami Aceh masih berlanjut dalam jangka panjang, mempengaruhi kesejahteraan psikologis secara signifikan. Hasil studi ini menekankan perlunya perhatian khusus terhadap kesehatan mental penyintas bencana, serta pentingnya program dukungan jangka panjang untuk memitigasi dampak psikologis pasca bencana jangka panjang

KEPUTUSAN PEMBELIAN MENGGUNAKAN PEMBAYARAN E-MONEY GOPAY

This research on electronic money aims to determine the factors that influence purchasing decisions. The factors is benefits, convenience and security factors. Of these three factors, which factor has the most influence on purchasing decisions using Gopay. The method used in this study was through a questionnaire distributed to 55 respondents consisting of employees and students of the University of Sultan Ageng Tirtayasa ranging in age from 17 to 50 years. Male respondents were 48.1 percent, while female respondents were 51.9 percent. The analytical tool used in this research is multiple linear regression. The results of the Summery model on SPSS, the amount of adjusted R² is 0.582, 58.2 percent of the variation in purchasing decisions can be explained by variations of the three independent variables, namely the benefit factor, the convenience factor and the safety factor. While the remaining 41.8 percent is explained by other reasons outside the model. The results of this study include the benefits and security factors significantly influence the purchase decision

UJI EFEKTIVITAS ANTIBAKTERI EKSTRAK NIGELLA SATIVA L. TERHADAP BAKTERI ESCHERICHIA COLI SECARA IN VITRO

Abstract—Infectious diseases remain a significant public health problem. One infectious disease can be caused by Escherichia coli. However, currently there is increasing resistance of Escherichia coli to several antibiotics. This has led to an increase in demand to develop new antibiotics that can overcome the development of resistance. Medicinal plants have enormous potential in the discovery of bioactive compounds that can fight resistant microorganisms. Nigella sativa L. is one such medicinal plant known for its antibacterial properties. The seed extract of Nigella sativa L. was obtained using the maceration method, resulting in four different concentrations: 12.5%, 25%, 50%, and 100%. These extracts were tested against Escherichia coli bacteria isolated on Mueller Hinton Agar media using the disk diffusion method. Nigella sativa L. seed extract with aquadest solvent produced average inhibition zone diameters of 0mm; 0mm; 0mm; 7mm, while with n-hexane solvent it produced average inhibition zone diameters of 0mm; 0mm; 0mm; 8.375mm at concentrations of 12.5%; 25%; 50%; 100%. The antibacterial activity of Nigella sativa L. seed extract was most effective at 100% concentration for both solvents. This study found no significant difference in antibacterial effectiveness between the aquadest and n-hexane solvent extracts of Nigella sativa L. against Escherichia coli. Keywords: nigella sativa L., rscherichia coli, antibacterial   Abstrak—Penyakit infeksi masih menjadi salah satu masalah kesehatan masyarakat yang penting. Salah satu penyakit infeksi dapat disebabkan oleh Escherichia coli. Namun, saat ini ada peningkatan resistensi Escherichia coli terhadap beberapa antibiotik. Hal ini menyebabkan peningkatan permintaan untuk mengembangkan antibiotik baru yang dapat mengatasi perkembangan resistensi. Tanaman obat memiliki potensi besar dalam penemuan senyawa bioaktif yang dapat melawan mikroorganisme resisten. Nigella sativa L. adalah salah satu tanaman obat yang dikenal memiliki sifat antibakteri. Ekstrak biji Nigella sativa L. diperoleh menggunakan metode maserasi, menghasilkan empat konsentrasi berbeda: 12,5%, 25%, 50%, dan 100%. Ekstrak-ekstrak ini diuji terhadap bakteri Escherichia coli yang diisolasi pada media Agar Mueller Hinton menggunakan metode difusi cakram. Ekstrak biji Nigella sativa L. dengan pelarut aquadest menghasilkan diameter zona hambat rata-rata 0mm; 0mm; 0mm; 7mm, sedangkan dengan pelarut n-heksana menghasilkan diameter zona hambat rata-rata 0mm; 0mm; 0mm; 8,375mm pada konsentrasi 12,5%; 25%; 50%; 100%. Aktivitas antibakteri ekstrak biji Nigella sativa L. paling efektif pada konsentrasi 100% untuk kedua pelarut. Penelitian ini menemukan tidak ada perbedaan signifikan dalam efektivitas antibakteri antara ekstrak pelarut aquadest dan n-heksana dari Nigella sativa L. terhadap Escherichia coli. Kata kunci: nigella sativa L., escherichia coli, antibakter

Curcuminoid Compounds Inhibit Macrophage Migration Inhibitory Factor: In Silico Study for Their Association to Anti-diabetic Potency

Abstract—Diabetes mellitus is a health problem characterized by chronic inflammation causing complications in the cardiovascular, kidneys, eyes, and nervous system, with macrophage migration inhibitory factor (MIF) protein playing a crucial function in the inflammatory process chain. MIF has been known as a signaling protein involved in the development of type 1 and type 2 diabetes mellitus (DM). There are several studies indicating that the development of type 1 and type 2 DM is influenced by the accumulation of macrophages in tissues susceptible to diabetic injury or infection. Curcuminoids, the bioactive components in turmeric, are known for their ability to decrease inflammation. This in silico study is intended to analyze the potential anti-inflammatory effect of curcuminoid in DM, with a specific focus on how it may reduce proinflammatory signals through MIF. The investigation involved predicting physicochemical, pharmacokinetic and toxicity (ADMET) qualities for curcuminoids, followed by molecular docking simulations with MIF as the target protein. The ADMET results showed curcumin and bisdemethoxycurcumin had favorable properties, while dimethoxycurcumin exhibited undesirable traits like low VDss. Therefore, molecular docking simulations were performed using curcumin and bisdemethoxycurcumin as ligands. The molecular docking simulations indicated that curcumin has a negative binding affinity slightly lower than (S, R)-3-(4-hydroxyphenyl)-4,5-dihydro-5-isoxazole acetic acid methyl ester (ISO-1), a reference MIF inhibitor; and bisdemethoxycurcumin binds to MIF even stronger than ISO-1, with interacting MIF amino acids Lys 32, Ile 64 Asn 97, Pro 1, and Tyr 95. Hence, the curcumin and bisdemethoxycurcumin compounds were found as having the potential to inhibit MIF activity that is associated with the progression of DM.  Keywords: curcuminoids, diabetes melitus (dm), inflammation, mif inhibitors, molecular docking   Abstrak—Diabetes mellitus (DM) merupakan masalah kesehatan yang ditandai dengan peradangan kronis, yang dapat menyebabkan komplikasi pada sistem kardiovaskular, ginjal, mata, dan sistem saraf. Protein macrophage migration inhibitory factor (MIF) memiliki peran penting dalam proses peradangan. MIF diketahui sebagai protein pensinyalan yang terlibat dalam perkembangan DM tipe 1 dan tipe 2. Beberapa penelitian menunjukkan bahwa perkembangan DM tipe 1 dan tipe 2 dipengaruhi oleh akumulasi makrofag pada jaringan yang rentan terhadap cedera atau infeksi akibat diabetes. Kurkuminoid, komponen bioaktif dalam kunyit, dikenal memiliki kemampuan untuk meringankan peradangan. Studi in silico ini bertujuan untuk menganalisis potensi efek antiinflamasi kurkuminoid terhadap DM, dengan fokus pada kemampuannya dalam menurunkan sinyal proinflamasi melalui MIF. Studi ini mencakup prediksi sifat fisikokimia, farmakokinetik, dan toksisitas (ADMET) kurkuminoid, yang dilanjutkan dengan simulasi molecular docking menggunakan MIF sebagai protein target. Hasil analisis ADMET menunjukkan bahwa kurkumin dan bisdemetoksikurkumin memiliki sifat yang menguntungkan, sedangkan dimetoksikurkumin menunjukkan karakteristik yang kurang diinginkan, seperti volume distribusi (VDss) yang rendah. Oleh karena itu, simulasi molecular docking dilakukan dengan menggunakan kurkumin dan bisdemetoksikurkumin sebagai ligan. Hasil simulasi molecular docking menunjukkan bahwa kurkumin memiliki afinitas pengikatan yang sedikit lebih rendah dibandingkan dengan (S, R)-3-(4-hydroxyphenyl)-4,5-dihydro-5-isoxazole acetic acid methyl ester (ISO-1), senyawa referensi inhibitor MIF. Sementara itu, bisdemetoksikurkumin menunjukkan ikatan yang lebih kuat dengan MIF dibandingkan ISO-1, dengan residu asam amino MIF yang berinteraksi meliputi Lys 32, Ile 64, Asn 97, Pro 1, dan Tyr 95. Dengan demikian, senyawa kurkumin dan bisdemetoksikurkumin berpotensi menghambat aktivitas MIF yang berperan dalam perkembangan DM.   Kata kunci: kurkuminoid, diabetes melitus (dm), peradangan, inhibitor mif, molecular docking

Pengaruh jenis Spesies Pillaring Agent Logam Si dalam proses Pilarisasi Bentonit Alam

Abstract—The pillarization process of natural bentonite from Pacitan, East Java has been carried out using the metal species Si in Na-silicate and TEOS. The pillarization process is carried out using direct pillarization and indirect pillarization methods. In this research, the number of moles of metal pillaring agent used was 5 mmol/gram bentonite. The pillarization process is carried out by mixing the natural bentonite suspension and pillaring agent at a temperature of 80oC and stirring for 5 hours using a hot plate stirrer. Pillars were formed in the calcination and oxidation stages at a temperature of 500oC using N2 and O2 gas flows for 1 hour and 5 hours respectively. The resulting material was characterized using the FTIR spectroscopy method, X-ray diffraction and N2 gas adsorption using the BET method. The characterization results show that TEOS species can form better and more homogeneous pore structures compared to silicate species. The direct pillarization method provides better and more homogeneous pillar heights compared to the indirect pillarization method. However, the pore size obtained is still on the micropore size scale observed using the N2 gas adsorption method with the BET method. Keywords: pillarization, si, teos, bentonite   Abstrak—Telah dilakukan proses pilarisasi bentonit alam asal Pacitan, Jawa Timur menggunakan spesies logam Si dalam Na-silikat dan TEOS. Proses pilarisasi yang dilakukan menggunakan metode pilarisasi langsung dan pilarisasi tidak langsung. Pada penelitian ini jumlah mol logam pillaring agent yang digunakan adlah 5 mmol/gram bentonit. Proses pilarisasi dilakukan dengan mencampurkan suspensi bentonit alam dan pillaring agent pada suhu 80oC dan diaduk selama 5 jam menggunakan hot plate stirrer. Pilar dibentuk pada tahap kalsinasi dan oksidasi pada suhu 500oC menggunakan aliran gas N2 dan O2 masing-masing selama 1 jam dan 5 jam. Material yang dihasilkan dikarakterisasi menggunakan metode spektroskopi FTIR, difraksi sinar-X dan adsorpsi gas N2 dengan metode BET. Hasil karakterisasi menunjukkan bahwa spesies TEOS dapat membentuk struktur pori lebih baik dan lebih homogen dibandingkan dengan spesies silikat. Metode plarisasi langsung memberikan tinggi pilar lebih baik dan lebih homogen dibandingkan dengan metode pilarisasi tidak langsung. Namun demikian ukuran pori yang diperoleh masih dalam skala ukuran mikropori yang diamati menggunakan metode adsorpsi gas N2 dengan metode BET. Kata kunci: pilarisasi, si, teos, bentonit &nbsp

Assessing The Impact of Financial Service Digitalization on SME Businesses In Lagos, Nigeria

Purpose: This paper examines the impact of digitalization on SMEs in Lagos Nigeria, especially in digital financial services. Method: The respondents for this study were 150 owners /managers of SMEs in Lagos, Nigeria and data were analyzed descriptively and inferentially using the chi-square test. The research adopts a quantitative research strategy to analyze the difference between SME performance before and after adopting the technology, analyze the degree of technology adoption by the SMEs, and Quantitative evaluation of the advantages of digital financial services. Result: The study found that digitalization has improved SME operations, enhancing efficiency, competitiveness, and access to financial services. However, challenges like internet connectivity and security issues remain unaddressed, necessitating targeted interventions and support strategies. To maximize digitalization's benefits, the study recommends government-led awareness campaigns to highlight the advantages of digital financial services for SMEs. Additionally, partnerships with telecom firms and government agencies should be established to expand broadband access and improve internet reliability in underserved areas. Finally, training programs for SME owners and staff are essential to ensure effective use of these financial services

Bridging Satisfaction to Loyalty: The Role of Service Quality and Customer Stickiness in Indonesia's Online Food Delivery Industry

Purpose: This study examines the influence of service quality dimensions which are tangibles, reliability, responsiveness, empathy, and assurance on customer satisfaction and their subsequent impact on customer loyalty in the context of online food delivery (OFD) services in Indonesia. Additionally, it explores the mediating role of customer stickiness in the relationship between customer satisfaction and loyalty. Method: The study employs a quantitative-explanatory research approach with a sample of 325 respondents, selected using purposive sampling. Data were collected through an online questionnaire and analyzed using Structural Equation Modeling-Partial Least Squares (SEM-PLS). Result: The findings reveal that tangibles and reliability are dominant factors influencing customer satisfaction. Customer satisfaction significantly enhances customer loyalty, primarily through the mediating role of customer stickiness. The SERVQUAL model was validated in the OFD context, highlighting the importance of improving service quality to foster customer satisfaction and loyalty

PENGARUH FIRM SIZE TERHADAP TAX AVOIDANCE DENGAN VARIABEL KINERJA KEUANGAN SEBAGAI VARIABEL KONTROL

This study examines the influence of firm size on tax avoidance, incorporating financial performance as a control variable through profitability indicators (Return on Assets and Return on Equity), liquidity (Current Ratio), and leverage (Debt to Equity Ratio). A quantitative research method was employed, utilizing purposive random sampling on 69 corporate taxpayers registered at the KPP Pratama Makassar Utara, specifically those located in the Makassar Industrial Area (KIMA), who had fulfilled their tax obligations during the 2021–2023 period. The findings indicate that firm size, profitability, and leverage have a significant impact on tax avoidance. In contrast, liquidity does not exhibit a significant effect on tax avoidance. Future research is recommended to expand alternative proxies for the variables employed in this study, such as total revenue for firm size, Net Profit Margin for profitability, Debt to Asset Ratio for leverage, and Cash Ratio for liquidity. Furthermore, future studies may consider broadening the research scope and exploring other industries to enhance the reliability of the findings

Study on the Banana Peel Hydrolysate for Lactic Acid Bacteria Growth Media

Abstract—Banana peel is food waste material that may contain certain beneficial nutrition and be useful for bacterial media production. This experiment aims to determine the effect of several variables which may have influence on the ability of banana peel to support probiotic growth. The thermal treatment used autoclave. In the hydrolysis step for probiotic growth, the variables studied were pH and temperature. The best result of hydrolysis was obtained by the initial steam treatment, followed by hydrolysis process at pH 4.5 and 95oC. The reducing sugar content obtained was 0.96 g/L. In the fermentation process, pure banana peel hydrolysate media was able produces to support Lactobacillus plantarum growth better than mixed media. The pure banana peel hydrolysate media could achieve up to 12.89 log CFU/ml. The amylase activity produced in the pure banana peel hydrolysate media was 8.14 DP. Keywords: banana, probiotic, hydrolysis, growth, amylase Abstrak—Kulit pisang merupakan bahan limbah yang memiliki kandungan nutrisi menguntungkan dan berguna untuk produksi media pertumbuhan bakteri. Penelitian ini bertujuan menentukan pengaruh beberapa variabel yang dapat mempengaruhi kulit pisang untuk mendukung pertumbuhan probiotik. Kulit pisang tersebut diolah melalui hidrolisis enzimatik menggunakan enzim amylase termofilik. Variabel sebelum proses hidrolisis adalah penggunaan pengolahan termal menggunakan uap air dan tanpa pengolahan. Pada langkah hidrolisis, variabel yang dipelajari adalah pH dan suhu. Hasil hidrolisa terbaik adalah dengan penggunaan pengolahan awal dengan uap air diikuti dengan hidrolisis pada pH 4,5 dan suhu 95oC. Kandungan gula pereduksi yang diperoleh sebesar 0,96 g/L. Pada proses fermentasi, media dari hidrolisat kulit pisang murni dapat menghasilkan pertumbuhan Lactobacillus plantarum sampai 12,89 log CFU/mL. Aktivitas amylase yang dihasilkan dari media hidrolisat kulit pisang tersebut adalah 8,14 DP. Keywords: pisang, probiotic, hydrolysis, growth, amylas