132 research outputs found
Exploring corporate social responsibility's global and Glocal practices in Qatar: A practitioner and stakeholder perspective
This study analysed corporate social responsibility (CSR) in the state of Qatar, aiming to determine the discipline’ global and glocal dimensions. The study investigated the notion that CSR remains western-driven in contrast to the scholarly trend that increasingly values national variables. Given the importance of CSR, the relationship between theory and contextual influences becomes a central element to evaluate the opportunity for specific corollaries to mainstream CSR. The methodology deployed for the study included a literature review, and interviews with practitioners and stakeholders. The results showed that although CSR as a concept is valid per se, an appropriate approach would value the operating environment as a key determinant, appreciating that specific cultural contexts necessitate variations to the mainstream theory
Electromagnetic corrections in hadronic processes
In quantum field theory, the splitting of the Hamiltonian into a strong and
an electromagnetic part cannot be performed in a unique manner. We propose a
convention for disentangling these two effects: one matches the parameters of
two theories -- with and without electromagnetic interactions -- at a given
scale mu_1, referred to as the matching scale. This procedure enables one to
analyze the separation of strong and electromagnetic contributions in a
transparent manner. We illustrate the method -- in the framework of the loop
expansion -- in a Yukawa model, as well as in the linear sigma model, where we
also investigate the corresponding low-energy effective theory.Comment: 19 pages (LaTex), 5 figures, published version. References in the
introduction added, discussion shortened, 1 figure removed, conclusions
unchange
The use of Focus Group Interviews to define the perceived importance of competencies related to the entrepreneurship as starting point for a new career in European athletes: an AtLETyC study
Critical Exponents of the N-vector model
Recently the series for two RG functions (corresponding to the anomalous
dimensions of the fields phi and phi^2) of the 3D phi^4 field theory have been
extended to next order (seven loops) by Murray and Nickel. We examine here the
influence of these additional terms on the estimates of critical exponents of
the N-vector model, using some new ideas in the context of the Borel summation
techniques. The estimates have slightly changed, but remain within errors of
the previous evaluation. Exponents like eta (related to the field anomalous
dimension), which were poorly determined in the previous evaluation of Le
Guillou--Zinn-Justin, have seen their apparent errors significantly decrease.
More importantly, perhaps, summation errors are better determined. The change
in exponents affects the recently determined ratios of amplitudes and we report
the corresponding new values. Finally, because an error has been discovered in
the last order of the published epsilon=4-d expansions (order epsilon^5), we
have also reanalyzed the determination of exponents from the epsilon-expansion.
The conclusion is that the general agreement between epsilon-expansion and 3D
series has improved with respect to Le Guillou--Zinn-Justin.Comment: TeX Files, 27 pages +2 figures; Some values are changed; references
update
Proteome sequence features carry signatures of the environmental niche of prokaryotes
<p>Abstract</p> <p>Background</p> <p>Prokaryotic environmental adaptations occur at different levels within cells to ensure the preservation of genome integrity, proper protein folding and function as well as membrane fluidity. Although specific composition and structure of cellular components suitable for the variety of extreme conditions has already been postulated, a systematic study describing such adaptations has not yet been performed. We therefore explored whether the environmental niche of a prokaryote could be deduced from the sequence of its proteome. Finally, we aimed at finding the precise differences between proteome sequences of prokaryotes from different environments.</p> <p>Results</p> <p>We analyzed the proteomes of 192 prokaryotes from different habitats. We collected detailed information about the optimal growth conditions of each microorganism. Furthermore, we selected 42 physico-chemical properties of amino acids and computed their values for each proteome. Further, on the same set of features we applied two fundamentally different machine learning methods, Support Vector Machines and Random Forests, to successfully classify between bacteria and archaea, halophiles and non-halophiles, as well as mesophiles, thermophiles and mesothermophiles. Finally, we performed feature selection by using Random Forests.</p> <p>Conclusions</p> <p>To our knowledge, this is the first time that three different classification cases (domain of life, halophilicity and thermophilicity) of proteome adaptation are successfully performed with the same set of 42 features. The characteristic features of a specific adaptation constitute a signature that may help understanding the mechanisms of adaptation to extreme environments.</p
Heterogeneity prevails: the state of clinical trial data management in Europe - results of a survey of ECRIN centres
Retail innovation and shopping practices: consumers' reaction to self-service retailing
Authors' draft also available on Surrey eprints repository at http://epubs.surrey.ac.uk. Final version available online at http://www.envplan.com/In this paper we address the related issues of retail innovation, changing shopping practices, and shopping geographies. We do so in relation to the spread of self-service grocery stores, and particularly the supermarket, in the postwar retail environment of Britain (1950 – 70), arguing that this juncture provides a propitious opportunity to study the relationship between changing practices of retailing and consumption. We highlight shoppers’ selective adoption of new self-service formats in relation to certain product categories and argue that this can be explained in part by reference to the socially embedded nature of women food shoppers’ behaviours and in particular the influence of contemporary notions of the ‘good housewife’. We support our argument by reference to a wide range of contemporary documentary material relating to postwar shopping including market research reports, the publications of local consumer groups, and selected retailer and government archive sources
Impact of renal impairment on atrial fibrillation: ESC-EHRA EORP-AF Long-Term General Registry
Background: Atrial fibrillation (AF) and renal impairment share a bidirectional relationship with important pathophysiological interactions. We evaluated the impact of renal impairment in a contemporary cohort of patients with AF. Methods: We utilised the ESC-EHRA EORP-AF Long-Term General Registry. Outcomes were analysed according to renal function by CKD-EPI equation. The primary endpoint was a composite of thromboembolism, major bleeding, acute coronary syndrome and all-cause death. Secondary endpoints were each of these separately including ischaemic stroke, haemorrhagic event, intracranial haemorrhage, cardiovascular death and hospital admission. Results: A total of 9306 patients were included. The distribution of patients with no, mild, moderate and severe renal impairment at baseline were 16.9%, 49.3%, 30% and 3.8%, respectively. AF patients with impaired renal function were older, more likely to be females, had worse cardiac imaging parameters and multiple comorbidities. Among patients with an indication for anticoagulation, prescription of these agents was reduced in those with severe renal impairment, p <.001. Over 24 months, impaired renal function was associated with significantly greater incidence of the primary composite outcome and all secondary outcomes. Multivariable Cox regression analysis demonstrated an inverse relationship between eGFR and the primary outcome (HR 1.07 [95% CI, 1.01–1.14] per 10 ml/min/1.73 m2 decrease), that was most notable in patients with eGFR <30 ml/min/1.73 m2 (HR 2.21 [95% CI, 1.23–3.99] compared to eGFR ≥90 ml/min/1.73 m2). Conclusion: A significant proportion of patients with AF suffer from concomitant renal impairment which impacts their overall management. Furthermore, renal impairment is an independent predictor of major adverse events including thromboembolism, major bleeding, acute coronary syndrome and all-cause death in patients with AF
Neanderthal behaviour, diet, and disease inferred from ancient DNA in dental calculus
Recent genomic data have revealed multiple interactions between Neanderthals and modern humans, but there is currently little genetic evidence regarding Neanderthal behaviour, diet, or disease. Here we describe the shotgun-sequencing of ancient DNA from five specimens of Neanderthal calcified dental plaque (calculus) and the characterization of regional differences in Neanderthal ecology. At Spy cave, Belgium, Neanderthal diet was heavily meat based and included woolly rhinoceros and wild sheep (mouflon), characteristic of a steppe environment. In contrast, no meat was detected in the diet of Neanderthals from El Sidrón cave, Spain, and dietary components of mushrooms, pine nuts, and moss reflected forest gathering. Differences in diet were also linked to an overall shift in the oral bacterial community (microbiota) and suggested that meat consumption contributed to substantial variation within Neanderthal microbiota. Evidence for self-medication was detected in an El Sidrón Neanderthal with a dental abscess and a chronic gastrointestinal pathogen (Enterocytozoon bieneusi). Metagenomic data from this individual also contained a nearly complete genome of the archaeal commensal Methanobrevibacter oralis (10.2× depth of coverage)-the oldest draft microbial genome generated to date, at around 48,000 years old. DNA preserved within dental calculus represents a notable source of information about the behaviour and health of ancient hominin specimens, as well as a unique system that is useful for the study of long-term microbial evolution
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