Neutrino Phenomenology in a 3+1+1 Framework

Evidence continues to grow in the MiniBooNE (MB) antineutrino mode supporting a low-energy excess compatible with the MB neutrino mode and possibly also confirming the results of the LSND experiment. At least one sterile neutrino is required to explain the anomalies consistent with the observations of other experiments. At the same time, there is a strong tension between the positive signals of LSND and MB and the null results of nu_e and nu_mu disappearance experiments. We explore a scenario, first proposed in \cite{Nelson:2010hz}, where the presence of an additional heavy sterile neutrino (with mass well above an eV) can alleviate tension between LSND, MB and the null results of disappearance experiments. We compare and contrast this 3+1+1 scenario with the more standard 3+1 scenario and carry out global fits to all oscillation data including new 2011 MB anti-nu data. We find that the tension can be somewhat alleviated and that a phenomenologically viable window for the heavy neutrino, consistent with rare decays and BBN constraints, can be found if the fifth neutrino has a mass of order 0.3 - 10 GeV. We also find, however, that the 2011 MB anti-nu data exacerbates the tension with null experiments in both the 3+1 and 3+1+1 models when the lowest energy bins are included, resulting in little improvement in the global fit. We also discuss the implications of an additional neutrino for the reactor and gallium anomalies, and show that an oscillation explanation of the anomalies is disfavored by cosmological considerations, direct searches, and precision electroweak tests.Comment: 22 pages, 5 figures; replaced to reflect journal versio

23 GHz VLBI Observations of SN 2008ax

We report on phase-referenced 23 GHz Very-Long-Baseline-Interferometry (VLBI) observations of the type IIb supernova SN 2008ax, made with the Very Long Baseline Array (VLBA) on 2 April 2008 (33 days after explosion). These observations resulted in a marginal detection of the supernova. The total flux density recovered from our VLBI image is 0.8$\pm$0.3 mJy (one standard deviation). As it appears, the structure may be interpreted as either a core-jet or a double source. However, the supernova structure could be somewhat confused with a possible close by noise peak. In such a case, the recovered flux density would decrease to 0.48$\pm$0.12 mJy, compatible with the flux densities measured with the VLA at epochs close in time to our VLBI observations. The lowest average expansion velocities derived from our observations are $(1.90 \pm 0.30) \times 10^5$ km s$^{-1}$ (case of a double source) and $(5.2 \pm 1.3) \times 10^4$ km s$^{-1}$ (taking the weaker source component as a spurious, close by, noise peak, which is the more likely interpretation). These velocities are 7.3 and 2 times higher, respectively, than the maximum ejecta velocity inferred from optical-line observations.Comment: 4 pages, 3 figures. Accepted in A&A on 24/03/200

A robust ex vivo method to evaluate the diffusion properties of agents in biological tissues

A robust method is presented for evaluating the diffusion properties of chemicals in ex vivo biological tissues. Using this method that relies only on thickness and collimated transmittance measurements, the diffusion properties of glycerol, fructose, polypropylene glycol and water in muscle tissues were evaluated. Amongst other results, the diffusion coefficient of glycerol in colorectal muscle was estimated with a value of 3.3 × 10−7 cm2/s. Due to the robustness and simplicity of the method, it can be used in other fields of biomedical engineering, namely in organ cryoprotection and food industry

An Intermediate Luminosity Transient in NGC300: The Eruption of a Dust-Enshrouded Massive Star

[abridged] We present multi-epoch high-resolution optical spectroscopy, UV/radio/X-ray imaging, and archival Hubble and Spitzer observations of an intermediate luminosity optical transient recently discovered in the nearby galaxy NGC300. We find that the transient (NGC300 OT2008-1) has a peak absolute magnitude of M_bol~-11.8 mag, intermediate between novae and supernovae, and similar to the recent events M85 OT2006-1 and SN2008S. Our high-resolution spectra, the first for this event, are dominated by intermediate velocity (~200-1000 km/s) hydrogen Balmer lines and CaII emission and absorption lines that point to a complex circumstellar environment, reminiscent of the yellow hypergiant IRC+10420. In particular, we detect broad CaII H&K absorption with an asymmetric red wing extending to ~1000 km/s, indicative of gas infall onto a massive and relatively compact star (blue supergiant or Wolf-Rayet star); an extended red supergiant progenitor is unlikely. The origin of the inflowing gas may be a previous ejection from the progenitor or the wind of a massive binary companion. The low luminosity, intermediate velocities, and overall similarity to a known eruptive star indicate that the event did not result in a complete disruption of the progenitor. We identify the progenitor in archival Spitzer observations, with deep upper limits from Hubble data. The spectral energy distribution points to a dust-enshrouded star with a luminosity of about 6x10^4 L_sun, indicative of a ~10-20 M_sun progenitor (or binary system). This conclusion is in good agreement with our interpretation of the outburst and circumstellar properties. The lack of significant extinction in the transient spectrum indicates that the dust surrounding the progenitor was cleared by the outburst.Comment: Submitted to ApJ; emulateapj style; 39 pages; 26 figure

Consequences of sexual harassment in sport for female athletes

Sexual harassment research was first undertaken in the workplace and educational settings. Research on sexual harassment in sport is scarce but has grown steadily since the mid-1980s. Even so, very little is known about the causes and/or characteristics and/or consequences of sexual harassment in sport settings. This article reports on the findings from interviews with 25 elite female athletes in Norway who indicated in a prior survey (N =572) that they had experienced sexual harassment from someone in sport. The consequences of the incidents of sexual harassment that were reported were mostly negative, but some also reported that their experiences of sexual harassment had had no consequences for them. “Thinking about the incidents”, a “destroyed relationship to the coach”, and “more negative view of men in general” were the most often negative consequences mentioned. In addition, a surprising number had chosen to move to a different sport or to drop out of elite sport altogether because of the harassment

Impact of antibiotic timing on mortality from Gram-negative bacteraemia in an English district general hospital: the importance of getting it right every time

Objectives: There is limited evidence that empirical antimicrobials affect patient-oriented outcomes in Gram-negative bacteraemia. We aimed to establish the impact of effective antibiotics at four consecutive timepoints on 30 day all-cause mortality and length of stay in hospital. / Methods: We performed a multivariable survival analysis on 789 patients with Escherichia coli, Klebsiella spp. and Pseudomonas aeruginosa bacteraemias. Antibiotic choices at the time of the blood culture (BC), the time of medical clerking and 24 and 48 h post-BC were reviewed. / Results: Patients that received ineffective empirical antibiotics at the time of the BC had higher risk of mortality before 30 days (HR = 1.68, 95% CI = 1.19–2.38, P = 0.004). Mortality was higher if an ineffective antimicrobial was continued by the clerking doctor (HR = 2.73, 95% CI = 1.58–4.73, P < 0.001) or at 24 h from the BC (HR = 1.83, 95% CI = 1.05–3.20, P = 0.033) when compared with patients who received effective therapy throughout. Hospital-onset infections, ‘high inoculum’ infections and elevated C-reactive protein, lactate and Charlson comorbidity index were independent predictors of mortality. Effective initial antibiotics did not statistically significantly reduce length of stay in hospital (−2.98 days, 95% CI = −6.08–0.11, P = 0.058). The primary reasons for incorrect treatment were in vitro antimicrobial resistance (48.6%), initial misdiagnosis of infection source (22.7%) and non-adherence to hospital guidelines (15.7%). / Conclusions: Consecutive prescribing decisions affect mortality from Gram-negative bacteraemia

Long-term outcome and risk factors for late mortality in Gram-negative bacteraemia: a retrospective cohort study

OBJECTIVES: The long-term outcomes of patients following Gram-negative bacteraemia (GNB) are poorly understood. We describe a cohort of patients with GNB over a two-year period and determine factors associated with late mortality (death between days 31 and 365 after detection of bacteraemia). METHODS: This is a single center retrospective observational cohort study of 789 patients with confirmed Escherichia coli, Klebsiella spp and Pseudomonas aeruginosa bacteraemias with a follow-up of one year. Multivariable survival analysis was used to determine the risk factors for late mortality in patients who survived the initial 30-day period of infection. RESULTS: Overall, one-year all-cause mortality was 36.2%, with 18.1% of patients dying within 30 days and 18.1% of patients suffering late mortality. An adverse antimicrobial resistance profile (HR 1.095 per any additional antimicrobial category, 95% CI 1.018 - 1.178, p = 0.014) and infection with Pseudomonas aeruginosa (HR 2.08, 95% CI 1.11 - 3.88, p = 0.022) were independent predictors of late mortality. Other significant factors included the Charlson Comorbidity Index and hospitalization length after the index blood culture. CONCLUSION: Patients with GNB have a poor long-term prognosis. Risk factors for greater mortality at one year include comorbidity, hospitalization length, the infecting organism, and its resistance profile

High-resolution observations of SN 2001gd in NGC 5033

We report on 8.4 GHz VLBI observations of SN2001gd in the spiral galaxy NGC5033 made on 26 June 2002 and 8 April 2003. Our data nominally suggests a relatively strong deceleration for the expansion of SN2001gd, but we cannot dismiss the possibility of a free supernova expansion. From our VLBI observations on 8 April 2003, we inferred a minimum total energy in relativistic particles and magnetic fields in the supernova shell of E_min =(0.3-14) 10^{47} ergs, and a corresponding equipartition average magnetic field of B_min = (50--350) mG. We also present multiwavelength VLA measurements of SN2001gd, which are well fit by an optically thin, synchrotron spectrum, partially absorbed by thermal plasma. We obtain a supernova flux density of (1.02 +/- 0.05) mJy at the observing frequency of 8.4 GHz for the second epoch, which results in an isotropic radio luminosity of (6.0 +/- 0.3) * 10^{36} ergs between 1.4 and 43.3 GHz, at an adopted distance of 13.1 Mpc. Finally, we report on an XMM-Newton X-ray detection of SN2001gd on 18 December 2002. The supernova X-ray spectrum is consistent with optically thin emission from a soft component (associated with emission from the reverse shock) at a temperature around 1 keV. The observed flux corresponds to an isotropic X-ray luminosity of L_X = 1.4 +/- 0.4 * 10^{39} ergs/s in the (0.3-5) keV band. We suggest that both radio and X-ray observations of SN2001gd indicate that a circumstellar interaction similar to that displayed by SN1993J in M81 is taking place.Comment: 9 pages, 6 figures, 2 tables, accepted for publication in MNRA

Accelerator and Reactor Neutrino Oscillation Experiments in a Simple Three-Generation Framework

We present a new approach to the analysis of neutrino oscillation experiments, in the one mass-scale limit of the three-generation scheme. In this framework we reanalyze and recombine the most constraining accelerator and reactor data, in order to draw precise bounds in the new parameter space. We consider our graphical representations as particularly suited to show the interplay among the different oscillation channels. Within the same framework, the discovery potential of future short and long baseline experiments is also investigated, in the light of both the recent signal from the LSND experiment and the atmospheric neutrino anomaly.Comment: uuencoded compressed tar file. Figures (13) available by ftp to ftp://eku.sns.ias.edu/pub/lisi/ (192.16.204.30). Submitted to Physical Review