271 research outputs found

    Techno-Economic Assessment of Offshore Wind and Hybrid Wind-Wave Farms with Energy Storage Systems

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    Ocean renewables (such as offshore wind and wave) are abundant and essential energy resources for supporting future emission-free targets. However, their energy intermittency and high cost have hindered commercialization and wide-scale implementations of these ocean energy technologies. This paper focuses on both issues and aims to increase the dispatchability of ocean energy farm, by investigating the potential of a hybrid wind and wave energy platform with various energy storage systems (ESSs). In the paper, a novel method is proposed to assess the ESS for an offshore renewable energy farm to guarantee the energy dispatchability to the local demand. The effect of two farm configurations on the ESS capacity is analysed: one involves wind turbines only and the other one uses a hybrid configuration (with wind and wave generation subsystems). Lifecycle cost models of energy farms are developed and the economic feasibility of different energy storage systems are investigated. The sensitivity of energy farm configurations and the energy storage systems to the resource characteristics at multiple locations are also studied. The results indicate that the combined wind and wave energy farm significantly reduces the energy storage system capacity requirement and provides competitive lifecycle costs compared to the stand-alone wind energy farm, though the amount of these benefits vary on the local resource characteristics. In addition, it was concluded that the Lithium-ion battery option in a combined energy farm offers better overall performance over the other storage options considered

    Yeni bir insansız hava aracının (SUAVİ) prototip üretimi ve algılayıcı-eyleyici entegrasyonu

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    Bu çalısmada, dört-döner rotoru ile helikopter gibi dikine kalkıs ve inis yapabilen aynı zamanda da uçak gibi uzun menzil yatay uçus yeteneğine sahip yeni bir insansız otonom hava aracının mekanik ve aerodinamik tasarımı, karbon kompozit imalatı, algılayıcı eyleyici sistem entegrasyonu ve uçus deneyleri anlatılmıstır. Gelistirilen sistem ve içinde kullanılan algılayıcı eyleyici entegrasyonunun basarımı benzetim ve deneylerle doğrulanmıstır

    Lithium promotes long-term neurological recovery after spinal cord injury in mice by enhancing neuronal survival, gray and white matter remodeling, and long-distance axonal regeneration

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    Spinal cord injury (SCI) induces neurological deficits associated with long-term functional impairments. Since the current treatments remain ineffective, novel therapeutic options are needed. Besides its effect on bipolar mood disorder, lithium was reported to have neuroprotective activity in different neurodegenerative conditions, including SCI. In SCI, the effects of lithium on long-term neurological recovery and neuroplasticity have not been assessed. We herein investigated the effects of intraperitoneally administered lithium chloride (LiCl) on motor coordination recovery, electromyography (EMG) responses, histopathological injury and remodeling, and axonal plasticity in mice exposed to spinal cord transection. At a dose of 0.2, but not 2.0 mmol/kg, LiCl enhanced motor coordination and locomotor activity starting at 28 days post-injury (dpi), as assessed by a set of behavioral tests. Following electrical stimulation proximal to the hemitransection, LiCl at 0.2 mmol/kg decreased the latency and increased the amplitude of EMG responses in the denervated hindlimb at 56 dpi. Functional recovery was associated with reduced gray and white matter atrophy rostral and caudal to the hemitransection, increased neuronal survival and reduced astrogliosis in the dorsal and ventral horns caudal to the hemitransection, and increased regeneration of long-distance axons proximal and distal to the lesion site in mice receiving 0.2 mmol/kg, but not 2 mmol/kg LiCl, as assessed by histochemical and immunohistochemical studies combined with anterograde tract tracing. Our results indicate that LiCl induces long-term neurological recovery and neuroplasticity following SCI.TUBA ; Istanbul Medipol University ; Turkish Academy of Science

    Presence of factors that activate platelet aggregation in mitral stenotic patients' plasma

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    BACKGROUND: Although the association between mitral stenosis (MS) and increased coagulation activity is well recognized, it is unclear whether enhanced coagulation remains localized in the left atrium or whether this represents a systemic problem. To assess systemic coagulation parameters and changes in platelet aggregation, we measured fibrinogen levels and performed in vitro platelet function tests in plasma obtained from mitral stenotic patients' and from healthy control subjects' peripheral venous blood. METHODS: Sixteen newly diagnosed patients with rheumatic MS (Group P) and 16 healthy subjects (Group N) were enrolled in the study. Platelet-equalized plasma samples were evaluated to determine in vitro platelet function, using adenosine diphosphate (ADP), collagen and epinephrine in an automated aggregometer. In vitro platelet function tests in group N were performed twice, with and without plasma obtained from group P. RESULTS: There were no significant differences between the groups with respect to demographic variables. Peripheral venous fibrinogen levels in Group P were not significantly different from those in Group N. Adenosine diphosphate, epinephrine and collagen-induced platelet aggregation ratios were significantly higher in Group P than in Group N. When plasma obtained from Group P was added to Group N subjects' platelets, ADP and collagen-induced, but not epinephrine-induced, aggregation ratios were significantly increased compared to baseline levels in Group N. CONCLUSION: Platelet aggregation is increased in patients with MS, while fibrinogen levels remain similar to controls. We conclude that mitral stenotic patients exhibit increased systemic coagulation activity and that plasma extracted from these patients may contain some transferable factors that activate platelet aggregation

    Crimean-Congo hemorrhagic fever: epidemiological trends and controversies in treatment

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    Crimean-Congo hemorrhagic fever (CCHF) virus has the widest geographic range of all tick-borne viruses and is endemic in more than 30 countries in Eurasia and Africa. Over the past decade, new foci have emerged or re-emerged in the Balkans and neighboring areas. Here we discuss the factors influencing CCHF incidence and focus on the main issue of the use of ribavirin for treating this infection. Given the dynamics of CCHF emergence in the past decade, development of new anti-viral drugs and a vaccine is urgently needed to treat and prevent this acute, life-threatening disease

    Landscape genomics and biased FST approaches reveal single nucleotide polymorphisms under selection in goat breeds of North-East Mediterranean

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    <p>Abstract</p> <p>Background</p> <p>In this study we compare outlier loci detected using a <it>F<smcaps>ST </smcaps></it>based method with those identified by a recently described method based on spatial analysis (SAM). We tested a panel of single nucleotide polymorphisms (SNPs) previously genotyped in individuals of goat breeds of southern areas of the Mediterranean basin (Italy, Greece and Albania). We evaluate how the SAM method performs with SNPs, which are increasingly employed due to their high number, low cost and easy of scoring.</p> <p>Results</p> <p>The combined use of the two outlier detection approaches, never tested before using SNP polymorphisms, resulted in the identification of the same three loci involved in milk and meat quality data by using the two methods, while the <it>F<smcaps>ST </smcaps></it>based method identified 3 more loci as under selection sweep in the breeds examined.</p> <p>Conclusion</p> <p>Data appear congruent by using the two methods for <it>F<smcaps>ST </smcaps></it>values exceeding the 99% confidence limits. The methods of <it>F<smcaps>ST </smcaps></it>and SAM can independently detect signatures of selection and therefore can reduce the probability of finding false positives if employed together. The outlier loci identified in this study could indicate adaptive variation in the analysed species, characterized by a large range of climatic conditions in the rearing areas and by a history of intense trade, that implies plasticity in adapting to new environments.</p
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