Demography and selection shape transcriptomic divergence in field crickets

Gene flow, demography, and selection can result in similar patterns of genomic variation and disentangling their effects is key to understanding speciation. Here, we assess transcriptomic variation to unravel the evolutionary history of Gryllus rubens and Gryllus texensis, cryptic field cricket species with highly divergent mating behavior. We infer their demographic history and screen their transcriptomes for footprints of selection in the context of the inferred demography. We find strong support for a long history of bidirectional gene flow, which ceased during the late Pleistocene, and a bottleneck in G. rubens consistent with a peripatric origin of this species. Importantly, the demographic history has likely strongly shaped patterns of genetic differentiation (empirical F-ST distribution). Concordantly, F-ST-based selection detection uncovers a large number of outliers, likely comprising many false positives, echoing recent theoretical insights. Alternative genetic signatures of positive selection, informed by the demographic history of the sibling species, highlighted a smaller set of loci; many of these are candidates for controlling variation in mating behavior. Our results underscore the importance of demography in shaping overall patterns of genetic divergence and highlight that examining both demography and selection facilitates a more complete understanding of genetic divergence during speciation

The transmission of trauma in refugee families: associations between intra-family trauma communication style, children’s attachment security and psychosocial adjustment

This study explores the transmission of trauma in 30 Middle Eastern refugee families in Denmark, where one or both parents were referred for treatment of PTSD symptoms and had non-traumatized children aged 4–9 years. The aim of the study was to explore potential risk and protective factors by examining the association between intra-family communication style regarding the parents’ traumatic experiences from the past, children’s psychosocial adjustment and attachment security. A negative impact of parental trauma on children might be indicated, as children’s Total Difficulties Scores on the Strengths and Difficulties Questionnaire (SDQ) were significantly higher than the Danish norms. A negative association between children’s attachment security as measured by the Attachment and Traumatization Story Task and higher scores on the SDQ Total Difficulties Scale approached significance, suggesting that the transmission of trauma may be associated with disruptions in children’s attachment representations. Furthermore a significant association between parental trauma communication and children’s attachment style was found

Substance-Related Health Problems during Rave Parties in the Netherlands (1997–2008)

The objective of this study was to describe a 12-year (1997–2008) observation of substance-related incidents occurring at rave parties in the Netherlands, including length of visits to first-aid stations, substances used, and severity of the incidents. During rave parties, specifically trained medical and paramedical personnel staffed first aid stations. Visitors were diagnosed and treated, and their data were recorded using standardized methods. During the 12-year period with 249 rave parties involving about 3,800,000 visitors, 27,897 people visited a first aid station, of whom 10,100 reported having a substance-related problem. The mean age of these people was 22.3+/−5.4 years; 52.4% of them were male. Most (66.7%) substance-related problems were associated with ecstasy or alcohol use or both. Among 10,100 substance-related cases, 515 required professional medical care, and 16 of these cases were life threatening. People with a substance-related problem stayed 20 min at the first aid station, which was significantly longer than the 5 min that those without a substance-related health problem stayed. These unique data from the Netherlands identify a variety of acute health problems related to the use of alcohol, amphetamines, cannabis, cocaine, ecstasy, and GHB. Although most problems were minor, people using GHB more often required professional medical care those using the other substances. We recommended adherence to harm and risk reduction policy, and the use of first aid stations with specially trained staff for both minor and serious incidents

Use of SMS texts for facilitating access to online alcohol interventions: a feasibility study

A41 Use of SMS texts for facilitating access to online alcohol interventions: a feasibility study In: Addiction Science & Clinical Practice 2017, 12(Suppl 1): A4

Key player identification: A note on weighted connectivity games and the Shapley Value

The use of graph theory in social network analysis to identify the most important actors is well-known. More recently game theory has also been applied to measure centrality as variation in the power due to the social structure. Here we present such a solution concept from cooperative game theory, the Shapley value, to identify key players engaged in a network. The communication structure among the players is modeled by use of the so-called connectivity game. We analyze standard networks representative of covert organizations and present results on the centrality of players organized according to an a-symmetric path structure. In addition we present an analysis of a weighted connectivity game in which the worth of coalitions not only depends on their interaction structure but also on exogenous factors

COTS selection best practices in literature and in industry

This paper presents an extensive literature survey of the software COTS component selection methods published to date, followed by a meta-model consolidating the activities and practices of these methods. Together with data collected from practitioners and researchers in the embedded systems domain, we provide concrete recommendations which will enable organizations to identify suitable practices when designing a customized selection processes

COTS selection best practices in literature and in industry

This paper presents an extensive literature survey of the software COTS component selection methods published to date, followed by a meta-model consolidating the activities and practices of these methods. Together with data collected from practitioners and researchers in the embedded systems domain, we provide concrete recommendations which will enable organizations to identify suitable practices when designing a customized selection processes