408 research outputs found

    The influence of hamstring extensibility on preselected saddle height within experienced competitive cyclists

    Get PDF
    Background: Contemporary studies have investigated the effects of bicycle saddle height for optimal performance and injury prevention. A recent review established a dynamic knee flexion angle of 25˚-30˚ for optimal economy, anaerobic power, and knee tracking (Bini et al., 2011: Sports Medicine, 41, 463-476). Muyor et al, (2011: Journal of Human Kinetics, 29, 15-23), investigated hamstring extensibility within 96 highly trained cyclists. They concluded that shortened hamstrings had a negative influence over thoracic spinal curvature, yet no influence over saddle height. Whereas, Ferrer-Roca et al (2012: Journal of Strength and Conditioning Research, 26, 3025- 3029) examined 23 high level competitive male road cyclists and concluded that a lack of flexibility may have an influence over lower preselected saddle heights (> 40˚ knee flexion angle). Consequently, there remains uncertainty whether preselected saddle height may be dependent on hamstring extensibility. Purpose: The purpose of the study was to investigate the influence of hamstring extensibility on preselected saddle height within experienced competitive cyclists. It was suggested that preselected saddle height may be dependent on hamstring extensibility to enable a 25˚-30˚ knee flexion angle. Methods: Participants consisted of 32 moderate to high level male and female road cyclists (35.8 ± 8.4 years; 178.22 ± 11.0 cm; 77.7 ± 13.4 kg). They used their own individually set-up road bicycle, which was placed on an indoor wind trainer. Hamstring extensibility was measured using the passive knee extension test. Dynamic 2D analysis was used to measure bicycle knee flexion and passive knee extension angles. A cycling questionnaire was also used to determine experience, training and competition levels. Results: Pearson’s correlation coefficients revealed bicycle knee flexion angle, years cycling (r = -0.35, p 0.05). Discussion: Results suggest that sustained time period on the bike rather than hamstring extensibility determines preselected saddle height. In particular, being competitive for a longer duration precedes either volume or number of years cycling. However, it is apparent that in agreement with Muyor et al., (2011) a single variable such as hamstring length does not predetermine optimal saddle height. In addition, as suggested by Ferrer-Roca et al., (2012), experienced cyclists are unable to achieve a knee flexion angle of 25˚, unless they have sufficient flexibility. Conclusion: Results reveal that with experience, a competitive cyclist’s subjective and objective interpretation of their preselected saddle height becomes more consistent. Although hamstring extensibility does not appear to influence pre-selected saddle height, an initial 35˚ rather than 25˚ knee flexion angle is recommended. Future research should consider mixed methodologies, to further establish safe and effective recommendations for optimising bicycle fit. References Bini, R., Hume, P.A., & Croft, J.L. (2011). Effects of bicycle saddle height on knee injury risk and cycling performance. Sports Medicine, 41, 463-476. Ferrer-Roca, V., Roig, A., Galilea, P., & Garcia Lopez, J. (2012). Influence of saddle height on lower limb kinematics in well trained cyclists: static vs dynamic evaluation in bike fitting. Journal of Strength and Conditioning Research, 26, 3025- 3029. Muyor, J. M., Alacid, F., & Lopez-Minarro, P.A. (2011). Influence of hamstring muscles extensibility on spinal curvatures and pelvic tilt in highly trained cyclists. Journal of Human Kinetics, 29, 15-23

    Learning to Teach Argumentation: Research and development in the science classroom

    Get PDF
    The research reported in this study focuses on an investigation into the teaching of argumentation in secondary science classrooms. Over a one-year period, a group of 12 teachers from schools in the greater London area attended a series of workshops to develop materials and strategies to support the teaching of argumentation in scientific contexts. Data were collected at the beginning and end of the year by audio and video recording lessons where the teachers attempted to implement argumentation. To assess the quality of argumentation, analytical tools derived from Toulmin's argument pattern (TAP) were developed and applied to classroom transcripts. Analysis shows there was development in teachers' use of argumentation across the year. Results indicate that the pattern of use of argumentation is teacher-specific, as is the nature of change. To inform future professional development programmes, transcripts of five teachers, three showing a significant change and two no change, were analysed in more detail to identify features of teachers' oral contributions that facilitated and supported argumentation. The analysis showed that all teachers attempted to encourage a variety of processes involved in argumentation and that the teachers whose lessons included the highest quality of argumentation (TAP analysis) also encouraged higher order processes in their teaching. The analysis of teachers' facilitation of argumentation has helped to guide the development of in-service materials and to identify the barriers to learning in the professional development of less experienced teachers

    "The extreme penalty of the law": mercy and the death penalty as aspects of state power in colonial Nyasaland, c. 1903-47

    Get PDF
    Open access article.Capital punishment was the pinnacle of the colonial judicial system and its use of state violence, but has previously been neglected as a topic of historical research in Africa. This article is based on the case files and legal records of over 800 capital trials – predominantly for murder – dating between 1900 and 1947. It outlines the functioning of the legal system in Nyasaland and the tensions between “violence” and “humanitarianism” in the use and reform of the death penalty. Capital punishment was a political penalty as much as a judicial punishment, with both didactic and deterrent functions: it operated through mercy and the sparing of condemned lives as well as through executions. Mercy in Nyasaland was consistent with colonial political objectives and cultural values: it was decided not only on the facts of cases, but according to British conceptions of “justice”, “order”, “criminality”, and “African” behaviour. This article analyses the use of mercy in Nyasaland to provide a lens on the nature of colonial governance, and the tensions between African and colonial understandings of violence.Arts and Humanities Research Council (UK) and the Beit Fund, University of Oxfor

    Prediction of enteric methane production, yield and intensity of beef cattle using an intercontinental database

    Get PDF
    Enteric methane (CH4) production attributable to beef cattle contributes to global greenhouse gas emissions. Reliably estimating this contribution requires extensive CH4 emission data from beef cattle under different management conditions worldwide. The objectives were to: 1) predict CH4 production (g d¬-1 animal-1), yield [g (kg dry matter intake; DMI)-1] and intensity [g (kg average daily gain)-1] using an intercontinental database (data from Europe, North America, Brazil, Australia and South Korea); 2) assess the impact of geographic region, and of higher- and lower-forage diets. Linear models were developed by incrementally adding covariates. A K-fold cross-validation indicated that a CH4 production equation using only DMI that was fitted to all available data had a root mean square prediction error (RMSPE; % of observed mean) of 31.2%. Subsets containing data with ≥ 25% and ≤ 18% dietary forage contents had an RMSPE of 30.8 and 34.2%, with the all-data CH4 production equation, whereas these errors decreased to 29.3 and 28.4%, respectively, when using CH4 prediction equations fitted to these subsets. The RMSPE of the ≥ 25% forage subset further decreased to 24.7% when using multiple regression. Europe- and North America-specific subsets predicted by the best performing ≥ 25% forage multiple regression equation had RMSPE of 24.5 and 20.4%, whereas these errors were 24.5 and 20.0% with region-specific equations, respectively. The developed equations had less RMSPE than extant equations evaluated for all data (22.5 vs. 23.2%), for higher-forage (21.2 vs. 23.1%), but not for the lower-forage subsets (28.4 vs. 27.9%). Splitting the dataset by forage content did not improve CH4 yield or intensity predictions. Predicting beef cattle CH4 production using energy conversion factors, as applied by the Intergovernmental Panel on Climate Change, indicated that adequate forage content-based and region-specific energy conversion factors improve prediction accuracy and are preferred in national or global inventories

    Comprehensive mRNA Expression Profiling Distinguishes Tauopathies and Identifies Shared Molecular Pathways

    Get PDF
    Background: Understanding the aetiologies of neurodegenerative diseases such as Alzheimer's disease (AD), Pick's disease (PiD), Progressive Supranuclear Palsy (PSP) and Frontotemporal dementia (FTD) is often hampered by the considerable clinical and molecular overlap between these diseases and normal ageing. The development of high throughput genomic technologies such as microarrays provide a new molecular tool to gain insight in the complexity and relationships between diseases, as they provide data on the simultaneous activity of multiple genes, gene networks and cellular pathways. Methodology/Principal Findings: We have constructed genome wide expression profiles from snap frozen post-mortem tissue from the medial temporal lobe of patients with four neurodegenerative disorders (5 AD, 5 PSP, 5 PiD and 5 FTD patients) and 5 control subjects. All patients were matched for age, gender, ApoE-e and MAPT (tau) haplotype. From all groups a total of 790 probes were shown to be differently expressed when compared to control individuals. The results from these experiments were then used to investigate the correlations between clinical, pathological and molecular findings. From the 790 identified probes we extracted a gene set of 166 probes whose expression could discriminate between these disorders and normal ageing. Conclusions/Significance: From genome wide expression profiles we extracted a gene set of 166 probes whose expression could discriminate between neurological disorders and normal ageing. This gene set can be further developed into an accurate microarray-based classification test. Furthermore, from this dataset we extracted a disease specific set of genes and identified two aging related transcription factors (FOXO1A and FOXO3A) as possible drug targets related to neurodegenerative disease

    Economic hardship associated with managing chronic illness: a qualitative inquiry

    Get PDF
    <p>Abstract</p> <p>Background</p> <p>Chronic illness and disability can have damaging, even catastrophic, socioeconomic effects on individuals and their households. We examined the experiences of people affected by chronic heart failure, complicated diabetes and chronic obstructive pulmonary disease to inform patient centred policy development. This paper provides a first level, qualitative understanding of the economic impact of chronic illness.</p> <p>Methods</p> <p>Interviews were conducted with patients aged between 45 and 85 years who had one or more of the index conditions and family carers from the Australian Capital Territory and Western Sydney, Australia (n = 66). Content analysis guided the interpretation of data.</p> <p>Results</p> <p>The affordability of medical treatments and care required to manage illness were identified as the key aspects of economic hardship, which compromised patients' capacity to proactively engage in self-management and risk reduction behaviours. Factors exacerbating hardship included ineligibility for government support, co-morbidity, health service flexibility, and health literacy. Participants who were on multiple medications, from culturally and linguistically diverse or Indigenous backgrounds, and/or not in paid employment, experienced economic hardship more harshly and their management of chronic illness was jeopardised as a consequence. Economic hardship was felt among not only those ineligible for government financial supports but also those receiving subsidies that were insufficient to meet the costs of managing long-term illness over and above necessary daily living expenses.</p> <p>Conclusion</p> <p>This research provides insights into the economic stressors associated with managing chronic illness, demonstrating that economic hardship requires households to make difficult decisions between care and basic living expenses. These decisions may cause less than optimal health outcomes and increased costs to the health system. The findings support the necessity of a critical analysis of health, social and welfare policies to identify cross-sectoral strategies to alleviate such hardship and improve the affordability of managing chronic conditions. In a climate of global economic instability, research into the economic impact of chronic illness on individuals' health and well-being and their disease management capacity, such as this study, provides timely evidence to inform policy development.</p

    Patient characteristics, comorbidities, and medication use for children with ADHD with and without a co-occurring reading disorder: A retrospective cohort study

    Get PDF
    <p>Abstract</p> <p>Background</p> <p>Children and adolescents with attention-deficit/hyperactivity disorder (ADHD) often have a co-occurring reading disorder (RD). The purpose of this research was to assess differences between children with ADHD without RD (ADHD-only) and those with ADHD and co-occurring RD (ADHD+RD).</p> <p>Methods</p> <p>Using data from the U.S. Thomson Reuter Marketscan<sup>® </sup>Databases for the years 2005 through 2007, this analysis compared the medical records--including patient demographics, comorbidities, and medication use--of children (age < 18) with ADHD-only to those with ADHD+RD.</p> <p>Results</p> <p>Patients with ADHD+RD were significantly younger, more likely to have received a procedure code associated with formal psychological or non-psychological testing, and more likely to have been diagnosed with comorbid bipolar disorder, conduct disorder, or depression. They were no more likely to have received an antidepressant, anti-manic (bipolar), or antipsychotic, and were significantly less likely to have received a prescription for a stimulant medication.</p> <p>Conclusions</p> <p>Relying on a claims database, there appear to be differences in the patient characteristics, comorbidities, and medication use when comparing children with ADHD-only to those with ADHD+RD.</p
    corecore