Diversity and Change: Asian American and Pacific Islander Workers

About 7.4 million Asian Americans and Pacific Islanders (AAPI) work in the United States, making up 5.3 percent of the total U.S. workforce. About 7.1 million of these AAPI workers are Asian Americans; about 300,000 are Pacific Islanders. The AAPI workforce is almost 20 times larger today than it was in 1960. Meanwhile, the share of AAPIs in the total workforce has increased about tenfold over the same period. Three broad themes emerge from our analysis of the data: The first is that AAPI workers are highly diverse. The second theme is that AAPI workers face many challenges in the labor market. The final theme is that the trends in the economic circumstances of AAPI workers have closely mirrored those of the broader workforce

Primary carcinosarcoma of the gallbladder

Carcinosarcoma of gallbladder (CSGB) is a rare malignancy characterized by malignant epithelial and mesenchymal components. Its pathogenesis is unknown and most CSGBs are associated with poor survival because the disease normally presents at an advanced stage, and as a result, curative resection is uncommon. This report describes a case that underwent curative resection. A 77-year-old woman presented with right upper quadrant pain. The preoperative diagnosis was gallbladder (GB) cancer, and thus, curative radical cholecystectomy was performed. However, pathologic examination of the surgical specimen revealed that the tumor was composed of two histologic components of squamous cell carcinoma and spindle cell sarcoma, which was consistent with a diagnosis of carcinosarcoma. The tumor was found to extend to the perimuscular connective tissue and to have metastasized to one lymph node (LN). The prognosis of CSGB remains poor despite curative resection, and thus, the authors recommend that effort be made to improve surgical outcomes

25th annual computational neuroscience meeting: CNS-2016

The same neuron may play different functional roles in the neural circuits to which it belongs. For example, neurons in the Tritonia pedal ganglia may participate in variable phases of the swim motor rhythms [1]. While such neuronal functional variability is likely to play a major role the delivery of the functionality of neural systems, it is difficult to study it in most nervous systems. We work on the pyloric rhythm network of the crustacean stomatogastric ganglion (STG) [2]. Typically network models of the STG treat neurons of the same functional type as a single model neuron (e.g. PD neurons), assuming the same conductance parameters for these neurons and implying their synchronous firing [3, 4]. However, simultaneous recording of PD neurons shows differences between the timings of spikes of these neurons. This may indicate functional variability of these neurons. Here we modelled separately the two PD neurons of the STG in a multi-neuron model of the pyloric network. Our neuron models comply with known correlations between conductance parameters of ionic currents. Our results reproduce the experimental finding of increasing spike time distance between spikes originating from the two model PD neurons during their synchronised burst phase. The PD neuron with the larger calcium conductance generates its spikes before the other PD neuron. Larger potassium conductance values in the follower neuron imply longer delays between spikes, see Fig. 17.Neuromodulators change the conductance parameters of neurons and maintain the ratios of these parameters [5]. Our results show that such changes may shift the individual contribution of two PD neurons to the PD-phase of the pyloric rhythm altering their functionality within this rhythm. Our work paves the way towards an accessible experimental and computational framework for the analysis of the mechanisms and impact of functional variability of neurons within the neural circuits to which they belong

Diversity and Change: Asian American and Pacific Islander Workers

In this report, we provide a statistical overview of the AAPI workforce in the United States. Three broad themes emerge from our analysis of the data. The first is that AAPI workers are highly diverse. AAPIs come from dozens of national and ethnic backgrounds. They speak many languages, from English to Chinese to Hindi. Three-fourths are immigrants. They are concentrated in the Pacific Coast region and the East Coast, but have a presence in every state in the country. They are more likely than whites to have a college degree, but they are also less likely than whites to have finished high school. The top 20 occupations held by AAPI workers range from doctors and computer engineers to hotel room cleaners and cashiers