Intensity Variations of H Alpha and N II 6 583 A Lines in the Night Sky Spectrum

Intensity variations of H alpha and N II 6 583 A lines in night sky spectru

Effect of the green-emitting CaF2:Ce3+,Tb3+ phosphor particles’ size on color rendering index and color quality scale of the in-cup packaging multichip white LEDs

In this paper, we investigate the effect of the green-emitting CaF2:Ce (3+), Tb (3+) phosphor particle's size on the color rendering index (CRI) and the color quality scale (CQS) of the in-cup packaging multichip white LEDs (MCW-LEDs). For this purpose, 7000K and 8500K in-cup packaging MCW-LEDs is simulated by the commercial software Light Tools. Moreover, scattering process in the phosphor layers is investigated by using Mie Theory with Mat Lab software. Finally, the research results show that the green-emitting CaF2: Ce (3+), Tb (3+) phosphor's size crucially influences on the CRI and CQS. From that point of view, CaF2: Ce (3+), Tb (3+) can be proposed as a potential practical direction for manufacturing the in-cup packaging phosphor WLEDs.Web of Science13235134

Early removal of senescent cells protects retinal ganglion cells loss in experimental ocular hypertension.

Experimental ocular hypertension induces senescence of retinal ganglion cells (RGCs) that mimics events occurring in human glaucoma. Senescence-related chromatin remodeling leads to profound transcriptional changes including the upregulation of a subset of genes that encode multiple proteins collectively referred to as the senescence-associated secretory phenotype (SASP). Emerging evidence suggests that the presence of these proinflammatory and matrix-degrading molecules has deleterious effects in a variety of tissues. In the current study, we demonstrated in a transgenic mouse model that early removal of senescent cells induced upon elevated intraocular pressure (IOP) protects unaffected RGCs from senescence and apoptosis. Visual evoked potential (VEP) analysis demonstrated that remaining RGCs are functional and that the treatment protected visual functions. Finally, removal of endogenous senescent retinal cells after IOP elevation by a treatment with senolytic drug dasatinib prevented loss of retinal functions and cellular structure. Senolytic drugs may have the potential to mitigate the deleterious impact of elevated IOP on RGC survival in glaucoma and other optic neuropathies

Men\u27s Ensemble and University Chorale Fall Choral Concert

KSU School of Music presents KSU Men\u27s Ensemble and University Chorale Fall Choral Concert with special guest artist Huu Mai, directed by Dr. Leslie Blackwell, Director of Choral Activities.https://digitalcommons.kennesaw.edu/musicprograms/1965/thumbnail.jp

Catalytic Performance of La-Ni/Al2O3 Catalyst for CO2 Reforming of Ethanol

Bio-derived ethanol has been considered as an attractive and alternative feedstock for dry or steam reforming reactions to generate renewable hydrogen, which may be used for replacement of conventional fossil fuels. Ethanol dry reforming (EDR) is an environmentally-friendly process since it transforms greenhouse gas, CO2 to value-added products and ethanol can be easily obtained from biomass which is free of catalyst poisons (i.e. sulphur-containing compounds). However, there are currently limited studies regarding syngas production from EDR [1, 2]. Ni-based catalysts are commonly used for reforming reactions due to its capability of C-C bond rupture, relatively low cost and high availability compared to precious metals [2]. Nevertheless, carbonaceous deposition may considerably deteriorate catalytic activity and stability of Ni-based catalysts. La promoter reportedly hindered carbon deposition and improved catalytic activity [3]. Hence, the objective of this research was to investigate the effect of La promotion on 10%Ni/Al2O3 catalyst for EDR

Urocortin 2 Gene Transfer Improves Glycemic Control and Reduces Retinopathy and Mortality in Murine Insulin Deficiency.

Type 1 diabetes affects 20 million patients worldwide. Insulin is the primary and commonly the sole therapy for type 1 diabetes. However, only a minority of patients attain the targeted glucose control and reduced adverse events. We tested urocortin 2 gene transfer as single-agent therapy for insulin deficiency using two mouse models. Urocortin 2 gene transfer reduced blood glucose for months after a single intravenous injection, through increased skeletal muscle insulin sensitivity, increased insulin release in response to glucose stimulation, and increased plasma insulin levels before and during euglycemic clamp. The combined increases in both insulin availability and sensitivity resulted in improved glycemic indices-events that were not anticipated in these insulin-deficient models. In addition, urocortin 2 gene transfer reduced ocular manifestations of long-standing insulin deficiency such as vascular leak and improved retinal function. Finally, mortality was reduced by urocortin 2 gene transfer. The mechanisms for these beneficial effects included increased activities of AMP-activated protein kinase and Akt (protein kinase B) in skeletal muscle, increased skeletal muscle glucose uptake, and increased insulin release. These data suggest that urocortin 2 gene transfer may be a viable therapy for new onset type 1 diabetes and might reduce insulin needs in later stage disease