The effect of Reynolds number on turbulent drag reduction by streamwise travelling waves

This paper exploits the turbulent flow control method using streamwise travelling waves (Quadrio et al. J. Fluid Mech., vol. 627, 2009, pp. 161–178) to study the effect of Reynolds number on turbulent skin-friction drag reduction. Direct numerical simulations (DNS) of a turbulent channel flow subjected to the streamwise travelling waves of spanwise wall velocity have been performed at Reynolds numbers ranging from Reτ=200 to 1600. To the best of the authors’ knowledge, this is the highest Reynolds number attempted with DNS for this type of flow control. The present DNS results confirm that the effectiveness of drag reduction deteriorates, and the maximum drag reduction achieved by travelling waves decreases significantly as the Reynolds number increases. The intensity of both the drag reduction and drag increase is reduced with the Reynolds number. Another important finding is that the value of the optimal control parameters changes, even in wall units, when the Reynolds number is increased. This trend is observed for the wall oscillation, stationary wave, and streamwise travelling wave cases. This implies that, when the control parameters used are close to optimal values found at a lower Reynolds number, the drag reduction deteriorates rapidly with increased Reynolds number. In this study, the effect of Reynolds number for the travelling wave is quantified using a scaling in the form Re−ατ. No universal constant is found for the scaling parameter α. Instead, the scaling parameter α has a wide range of values depending on the flow control conditions. Further Reynolds number scaling issues are discussed. Turbulent statistics are analysed to explain a weaker drag reduction observed at high Reynolds numbers. The changes in the Stokes layer and also the mean and root-mean-squared (r.m.s.) velocity with the Reynolds number are also reported. The Reynolds shear stress analysis suggests an interesting possibility of a finite drag reduction at very high Reynolds numbers

The U.S.-China trade war and policy resilience

One can attribute the Trump administration's pursuit of a trade war against the People's Republic of China (PRC) to a range of variables, including its re-election hopes, commitment to protectionism as an economic weapon, fears about Beijing's pursuit of artificial intelligence, and broader strategic concerns about the global balance of power. This article argues that another explanation for President Donald J. Trump's ability to change trade policy towards China was the structural weaknesses of the trade policy regime that emerged at the end of the 1990s when Congress adopted Permanent Normal Trade Relations as a designation for free trade in July 1998 and the prc joined the World Trade Organization in December 2001. Those weaknesses owed much to the ways in which the United States initially framed the new trade regime with the prc and the limited, only partially conclusive, character of the debate that took place at the time. Despite the growth and embedding of supply chains between China and the United States, these inbuilt weaknesses contributed to the progressive erosion of the trade policy regime during the years that followed. Within this context, few constituencies were ready to lobby for the prc after January 2017 and the Trump administration faced little opposition to its change of trade policy

Sperm competition risk drives plasticity in seminal fluid composition

Background Ejaculates contain a diverse mixture of sperm and seminal fluid proteins, the combination of which is crucial to male reproductive success under competitive conditions. Males should therefore tailor the production of different ejaculate components according to their social environment, with particular sensitivity to cues of sperm competition risk (i.e. how likely it is that females will mate promiscuously). Here we test this hypothesis using an established vertebrate model system, the house mouse (Mus musculus domesticus), combining experimental data with a quantitative proteomics analysis of seminal fluid composition. Our study tests for the first time how both sperm and seminal fluid components of the ejaculate are tailored to the social environment. Results Our quantitative proteomics analysis reveals that the relative production of different proteins found in seminal fluid – i.e. seminal fluid proteome composition – differs significantly according to cues of sperm competition risk. Using a conservative analytical approach to identify differential expression of individual seminal fluid components, at least seven of 31 secreted seminal fluid proteins examined showed consistent differences in relative abundance under high versus low sperm competition conditions. Notably three important proteins with potential roles in sperm competition – SVS 6, SVS 5 and CEACAM 10 – were more abundant in the high competition treatment groups. Total investment in both sperm and seminal fluid production also increased with cues of heightened sperm competition risk in the social environment. By contrast, relative investment in different ejaculate components was unaffected by cues of mating opportunities. Conclusions Our study reveals significant plasticity in different ejaculate components, with the production of both sperm and non-sperm fractions of the ejaculate strongly influenced by the social environment. Sperm competition risk is thus shown to be a key factor in male ejaculate production decisions, including driving plasticity in seminal fluid composition

Multimorbidity: Not Just for the West.

"A multimorbidity lens creates exciting opportunities to reconceptualise health and wellbeing in all its complexity. We need to improve health metrics to capture this complexity and strengthen health services to respond to it.

Accelerating the Translation of Nanomaterials in Biomedicine

Due to their size and tailorable physicochemical properties, nanomaterials are an emerging class of structures utilized in biomedical applications. There are now many prominent examples of nanomaterials being used to improve human health, in areas ranging from imaging and diagnostics to therapeutics and regenerative medicine. An overview of these examples reveals several common areas of synergy and future challenges. This Nano Focus discusses the current status and future potential of promising nanomaterials and their translation from the laboratory to the clinic, by highlighting a handful of successful examples

Ernst Freund as Precursor of the Rational Study of Corporate Law

Gindis, David, Ernst Freund as Precursor of the Rational Study of Corporate Law (October 27, 2017). Journal of Institutional Economics, Forthcoming. Available at SSRN: https://ssrn.com/abstract=2905547, doi: https://dx.doi.org/10.2139/ssrn.2905547The rise of large business corporations in the late 19th century compelled many American observers to admit that the nature of the corporation had yet to be understood. Published in this context, Ernst Freund's little-known The Legal Nature of Corporations (1897) was an original attempt to come to terms with a new legal and economic reality. But it can also be described, to paraphrase Oliver Wendell Holmes, as the earliest example of the rational study of corporate law. The paper shows that Freund had the intuitions of an institutional economist, and engaged in what today would be called comparative institutional analysis. Remarkably, his argument that the corporate form secures property against insider defection and against outsiders anticipated recent work on entity shielding and capital lock-in, and can be read as an early contribution to what today would be called the theory of the firm.Peer reviewe