A Study of the Effectiveness of Evangelistic Techniques with Chinese Christians: with Applications for the Mission Field of Taiwan

The call of missions cries out from the ends of the earth. Many millions of people have never heard the gospel and are waiting for someone to share the good news with them. Some have responded to this call of taking the gospel to the unsaved millions of the world, and others contemplate all of the many factors involved in doing missionary work. Missionary work needs to be defined here as cross-cultural evangelism in a foreign country which opens up a whole new set of problems in analyzing missionary work. This thesis will focus on the problems and issues facing missionaries attempting to plant churches in Taiwan. Next an analysis of research done with Chinese Christians will be explored followed up with suggested applications for present day missionaries in Taiwan. Finally, projected theories for developing an evangelistic strategy for the field of Taiwan will be explored. The study done with the Chinese in this thesis will not only benefit those considering doing missionary work in Taiwan but also will aid in developing strategies for evangelizing other mission fields in the world

HIghMass - High HI Mass, HI-Rich Galaxies at z∼0z\sim0: Combined HI and H2_2 Observations

We present resolved HI and CO observations of three galaxies from the HIghMass sample, a sample of HI-massive ($M_{HI} > 10^{10} M_\odot$), gas-rich ($M_{HI}$ in top $5\%$ for their $M_*$) galaxies identified in the ALFALFA survey. Despite their high gas fractions, these are not low surface brightness galaxies, and have typical specific star formation rates (SFR$/M_*$) for their stellar masses. The three galaxies have normal star formation rates for their HI masses, but unusually short star formation efficiency scale lengths, indicating that the star formation bottleneck in these galaxies is in the conversion of HI to H$_2$, not in converting H$_2$ to stars. In addition, their dark matter spin parameters ($\lambda$) are above average, but not exceptionally high, suggesting that their star formation has been suppressed over cosmic time but are now becoming active, in agreement with prior H$\alpha$ observations.Comment: 20 pages, 13 figure

Test-Anchored Vibration Response Predictions for an Acoustically Energized Curved Orthogrid Panel with Mounted Components

A rich body of vibroacoustic test data was recently generated at Marshall Space Flight Center for a curved orthogrid panel typical of launch vehicle skin structures. Several test article configurations were produced by adding component equipment of differing weights to the flight-like vehicle panel. The test data were used to anchor computational predictions of a variety of spatially distributed responses including acceleration, strain and component interface force. Transfer functions relating the responses to the input pressure field were generated from finite element based modal solutions and test-derived damping estimates. A diffuse acoustic field model was employed to describe the assumed correlation of phased input sound pressures across the energized panel. This application demonstrates the ability to quickly and accurately predict a variety of responses to acoustically energized skin panels with mounted components. Favorable comparisons between the measured and predicted responses were established. The validated models were used to examine vibration response sensitivities to relevant modeling parameters such as pressure patch density, mesh density, weight of the mounted component and model form. Convergence metrics include spectral densities and cumulative root-mean squared (RMS) functions for acceleration, velocity, displacement, strain and interface force. Minimum frequencies for response convergence were established as well as recommendations for modeling techniques, particularly in the early stages of a component design when accurate structural vibration requirements are needed relatively quickly. The results were compared with long-established guidelines for modeling accuracy of component-loaded panels. A theoretical basis for the Response/Pressure Transfer Function (RPTF) approach provides insight into trends observed in the response predictions and confirmed in the test data. The software modules developed for the RPTF method can be easily adapted for quick replacement of the diffuse acoustic field with other pressure field models; for example a turbulent boundary layer (TBL) model suitable for vehicle ascent. Wind tunnel tests have been proposed to anchor the predictions and provide new insight into modeling approaches for this type of environment. Finally, component vibration environments for design were developed from the measured and predicted responses and compared with those derived from traditional techniques such as Barrett scaling methods for unloaded and component-loaded panels

O&M Best Practices - A Guide to Achieving Operational Efficiency (Release 2.0)

This guide, sponsored by DOE's Federal Energy Management Program, highlights operations and maintenance (O&M) programs targeting energy efficiency that are estimated to save 5% to 20% on energy bills without a significant capital investment. The purpose of this guide is to provide the federal O&M energy manager and practitioner with useful information about O&M management, technologies, energy efficiency and cost-reduction approaches

Monitoring Base Specific Dynamics during Melting of DNA-Ligand Complexes using Temperature-Jump Time-Resolved Infrared Spectroscopy

Ultrafast time-resolved infrared spectroscopy employing nanosecond temperature-jump initiation has been used to study the melting of double-stranded (ds)DNA oligomers in the presence and absence of minor groove-binding ligand Hoechst 33258. Ligand binding to ds(5′-GCAAATTTCC-3′), which binds Hoechst 33258 in the central A-tract region with nanomolar affinity, causes a dramatic increase in the timescales for strand melting from 30 to 250 μs. Ligand binding also suppresses premelting disruption of the dsDNA structure, which takes place on 100 ns timescales and includes end-fraying. In contrast, ligand binding to the ds(5′-GCATATATCC-3′) sequence, which exhibits an order of magnitude lower affinity for Hoechst 33258 than the A-tract motif, leads to an increase by only a factor of 5 in melting timescales and reduced suppression of premelting sequence perturbation and end-fraying. These results demonstrate a dynamic impact of the minor groove ligand on the dsDNA structure that correlates with binding strength and thermodynamic stabilization of the duplex. Moreover, the ability of the ligand to influence base pairs distant from the binding site has potential implications for allosteric communication mechanisms in dsDNA

Sequence Dependent Melting and Refolding Dynamics of RNA UNCG Tetraloops Using Temperature-Jump/Drop Infrared Spectroscopy

Time-resolved temperature-jump/drop infrared (IR) spectroscopy has been used to measure the impact of stem base sequence on the melting and refolding dynamics of ribonucleic acid (RNA) tetraloops. A series of three 12-nucleotide RNA hairpin sequences were studied, each featuring a UACG tetraloop motif and a double-stranded stem containing four base pairs. In each case, the stem comprised three GC pairs plus a single AU base pair inserted at the closing point of the loop (RNAloop), in the middle of the stem (RNAmid), or at the stem terminus (RNAend). Results from analogous DNA tetraloop (TACG) sequences were also obtained. Inclusion of AU or AT base pairs in the stem leads to faster melting of the stem-loop structure compared to a stem sequence featuring four GC base pairs while refolding times were found to be slower, consistent with a general reduction in stem-loop stability caused by the AU/AT pair. Independent measurement of the dynamic timescales for melting and refolding of ring vibrational modes of guanine (GR) and adenine (AR) provided position-specific insight into hairpin dynamics. The GR-derived data showed that DNA sequences melted more quickly (0.5 ± 0.1 to 0.7 ± 0.1 μs at 70 °C) than analogous RNA sequences (4.3 ± 0.4 to 4.4 ± 0.3 μs at 70 °C). Position-sensitive data from the AR modes suggests that DNA hairpins begin melting from the terminal end of the stem toward the loop while RNA sequences begin melting from the loop. Refolding timescales for both RNA and DNA hairpins were found to be similar (250 ± 50 μs at 70 °C) except for RNAend and DNAloop which refolded much more slowly (746 ± 36 and 430 ± 31 μs, respectively), showing that the refolding pathway is significantly impaired by the placement of AU/AT pairs at different points in the stem. We conclude that conformational changes of analogous pairs of RNA and DNA tetraloops proceed by different mechanisms

Definitive locoregional therapy (LRT) versus bridging LRT and liver transplantation with wait-and-not-treat approach for very early stage hepatocellular carcinoma

PURPOSE:Since the change in the United Network for Organ Sharing (UNOS) policy excluding patients with very early stage hepatocellular carcinoma (veHCC, single tumor nodule <2 cm) from receiving Model for End-stage Liver Disease (MELD) exception points, patients eligible to receive liver transplantation (LT) who fall in this category are commonly treated with locoregional therapy (LRT) after progression to UNOS T2 stage (1 nodule of 2–5 cm or up to 3 nodules, none above 3 cm). The aim of the current study is to compare the outcomes of patients treated with bridging LRT and LT with wait-and-not-treat approach with patients treated with definitive LRT.METHODS:A retrospective study has been performed on patients with veHCC evaluated in multidisciplinary liver tumor clinic of a large academic center between 2004–2011. Patients eligible for LT were assigned to the wait-and-not-treat group while patients who were not eligible were assigned to the definitive LRT group. Tumor size, time to treatment, severity of liver disease, recurrence and survival from time of detection were reviewed and recorded.RESULTS:A total of 19 patients were identified and treated with definitive LRT while 57 patients were treated with bridging LRT prior to LT after disease progression to T2 stage. Patients in the definitive LRT group were older (70.4±10.2 years vs. 58.7±5.9 years, P < 0.001) and had more comorbid conditions compared with the wait-and-not-treat group. Mean survival for definitive LRT group at the end of 5 years was 34.3±6.0 months with a median of 30.3 months (95% CI, 5.7–55.0 months) compared with 48.7±2.6 months for the wait-and-not-treat group, respectively (median not reached). The 3- and 5-year survival rates were 53.3% and 33.3% for the definitive LRT group compared with 78.9% and 68.4% for the patients in the wait-and-not-treat group. Survival rate at the end of 5 years was significantly better for the wait-and-not-treat group (P = 0.013).CONCLUSION:Based on the findings of current retrospective study, treating veHCC (UNOS T1 stage) patients listed for LT with bridging LRT after disease progression to T2 stage appears to be safe and effective with high 5-year survival rates

LightBox: Full-stack Protected Stateful Middlebox at Lightning Speed

Running off-site software middleboxes at third-party service providers has been a popular practice. However, routing large volumes of raw traffic, which may carry sensitive information, to a remote site for processing raises severe security concerns. Prior solutions often abstract away important factors pertinent to real-world deployment. In particular, they overlook the significance of metadata protection and stateful processing. Unprotected traffic metadata like low-level headers, size and count, can be exploited to learn supposedly encrypted application contents. Meanwhile, tracking the states of 100,000s of flows concurrently is often indispensable in production-level middleboxes deployed at real networks. We present LightBox, the first system that can drive off-site middleboxes at near-native speed with stateful processing and the most comprehensive protection to date. Built upon commodity trusted hardware, Intel SGX, LightBox is the product of our systematic investigation of how to overcome the inherent limitations of secure enclaves using domain knowledge and customization. First, we introduce an elegant virtual network interface that allows convenient access to fully protected packets at line rate without leaving the enclave, as if from the trusted source network. Second, we provide complete flow state management for efficient stateful processing, by tailoring a set of data structures and algorithms optimized for the highly constrained enclave space. Extensive evaluations demonstrate that LightBox, with all security benefits, can achieve 10Gbps packet I/O, and that with case studies on three stateful middleboxes, it can operate at near-native speed.Comment: Accepted at ACM CCS 201

Services just for men? Insights from a national study of the well men services pilots.

Men continue to have a lower life expectancy in most countries compared to women. Explanations of this gendered health inequality tend to focus on male risk taking, unhealthy lifestyle choices and resistance to seeking help from health services. In the period 2005-2008 the Scottish Government funded a nationwide community health promotion programme aimed at improving men's health, called Well Men Service Pilots (henceforth WMS)