Accidental catheter removal in critically ill patients: a prospective and observational study

INTRODUCTION: The importance of accidental catheter removal (ACR) lies in the complications caused by the removal itself and by catheter reinsertion. To the best of our knowledge, no studies have analyzed accidental removal of various types of catheters in the intensive care unit (ICU). The objective of the present study was to analyze the incidence of ACR for all types of catheters in the ICU. METHODS: This was a prospective and observational study, conducted in a 24-bed medical/surgical ICU in a university hospital. We included all consecutive patients admitted to the ICU over 18 months (1 May 2000 to 31 October 2001). The incidences of ACR for all types of catheters (both per 100 catheters and per 100 catheter-days) were determined. RESULTS: A total of 988 patients were included. There were no significant differences in ACR incidence between the four central venous access sites (peripheral, jugular, subclavian and femoral) or between the four arterial access sites (radial, femoral, pedal and humeral). However, the incidence of ACR was higher for arterial than for central venous catheters (1.12/100 catheter-days versus 2.02/100 catheter-days; P < 0.001). The incidences of ACR/100 nonvascular catheter-days were as follows: endotracheal tube 0.79; nasogastric tube 4.48; urinary catheter 0.32; thoracic drain 0.56; abdominal drain 0.67; and intraventricular brain drain 0.66. CONCLUSION: We found ACR incidences for central venous catheter, arterial catheter, endotracheal tube, nasogastric tube and urinary catheter that are similar to those reported in previous studies. We could not find studies that analyzed the ACR for thoracic, abdominal, intraventricular brain and cardiac surgical drains, but we believe that our rates are acceptable. To minimize ACR, it is necessary to monitor its incidence carefully and to implement preventive measures. In our view, according to establish quality standards, findings should be reported as ACR incidence per 100 catheters and per 100 catheter-days, for all types of catheters

Superradiance mediated by Graphene Surface Plasmons

We demonstrate that the interaction between two emitters can be controlled by means of the efficient excitation of surface plasmon modes in graphene. We consider graphene surface plasmons supported by either two-dimensional graphene sheets or one-dimensional graphene ribbons, showing in both cases that the coupling between the emitters can be strongly enhanced or suppressed. The super- and subradiant regimes are investigated in the reflection and transmission configurations. Importantly, the length scale of the coupling between emitters, which in vacuum is fixed by the free space wavelength, is now determined by the wavelength of the graphene surface plasmons that can be extremely short and be tuned at will via a gate voltage

Reversible dynamics of single quantum emitters near metal-dielectric interfaces

Under the terms of the Creative Commons Attribution License 3.0 (CC-BY).Here we present a systematic study of the dynamics of a single quantum emitter near a flat metal-dielectric interface. We identify the key elements that determine the onset of reversibility in these systems by using a formalism suited for absorbing media and through an exact integration of the dynamics. Moreover, when the quantum emitter separation from the surface is small, we are able to describe the dynamics within a pseudomode description that yields analytical understanding and allows more powerful calculations.Work supported by the Spanish MINECO (MAT2011-22997, MAT2011-28581-C02, CSD2007-046-NanoLight.es) and CAM (S-2009/ESP-1503). A.G.-T. acknowledges funding by the EU integrated project SIQS. P.A.-H. acknowledges a FPU grant (AP2008-00021) from the Spanish Ministry of Education. This work has been partially funded by the European Research Council (ERC-2011-AdG Proposal No. 290981).Peer Reviewe

Moulding the flow of surface plasmons using conformal and quasiconformal mapping

In this paper we analyze how Transformation Optics recipes can be applied to control the flow of surface plasmons on metal-dielectric interfaces. We study in detail five different examples: a cylindrical cloak, a beam shifter, a right-angle bend, a lens and a ground-plane cloak. First, we demonstrate that only the modification of the electric permittivity and magnetic permeability in the dielectric side can lead to almost perfect functionalities for surface plasmons. We also show that, thanks to the quasi two-dimensional character of surface plasmons and its inherent polarization, the application of conformal and quasiconformal mapping techniques allows the design of plasmonic devices in which only the isotropic refractive index of the dielectric film needs to be engineered.Comment: To be published in New Journal of Physic

Hopelessness and HIV infection: an exploratory study with a gender-specific perspective

BACKGROUND: An understudied psychological response to HIV-related stressors among people living with HIV is hopelessness. Hopelessness is the expectation that things will not improve and feeling helpless to change one's current situation. The aim of this study was to assess prevalence and levels of hopelessness and its direct and indirect contributors in people living with HIV in Sweden. METHODS: Participants included 967 women and men from the "Living with HIV in Sweden" cross-sectional study with available data regarding hopelessness measured by the Beck Hopelessness Scale. Binary and multiple logistic regression analyses were used to determine direct and indirect factors that may contribute to feelings of hopelessness. Path analyses were used to assess the underlying structure of hopelessness. All analyses were conducted by gender. RESULTS: Almost half the participants reported moderate to severe hopelessness. There were no differences in frequency of feeling hopeless or level of hopelessness by gender or sexual orientation. Dissatisfaction with finances, dissatisfaction with physical health, and low HIV-related emotional support were found to be directly associated with hopelessness for both women and men. Although having some indirect factors in common, unemployment and HIV stigmatization, women and men had different underlying structures of hopelessness. CONCLUSIONS: Our findings are important to HIV clinicians in identifying those at risk of hopelessness from a gender perspective in order to reduce preventable psychological distress among people living with HIV

Insights from experiences comanaging woody invasive alien plants in Argentina

ACKNOWLEDGEMENTS Thanks to a long list of organisations and colleagues who supported our work. In particular, we want to acknowledge the technical team of CONTAIN (IER), Jardín Botánico de Horco Molle, Reserva Experimental de Horco Molle y Parque Sierra de San Javier, Paititi Foundation and E. Zugasti, Secretarías de Investigación y Extensión UNCo Bariloche, S. Seijas (Parque Nacional Nahuel Huapi), and Turisur. L. lucidum management was partially funded by the CONTAIN programme under the Newton Latin American Biodiversity Programme (NE/S011641/1), with contributions from NERC (UK) and CONICET 2019-74-APN-DIR#CONICET). P.G.-D. was supported by NE/S011641/1 and 2022GCBCCONTAIN.Peer reviewedPublisher PD

Isotropic and anisotropic surface wave cloaking techniques

In this paper we compare two different approaches for surface waves cloaking. The first technique is a unique application of Fermat's principle and requires isotropic material properties, but owing to its derivation is limited in its applicability. The second technique utilises a geometrical optics approximation for dealing with rays bound to a two dimensional surface and requires anisotropic material properties, though it can be used to cloak any smooth surface. We analytically derive the surface wave scattering behaviour for both cloak techniques when applied to a rotationally symmetric surface deformation. Furthermore, we simulate both using a commercially available full-wave electromagnetic solver and demonstrate a good level of agreement with their analytically derived solutions. Our analytical solutions and simulations provide a complete and concise overview of two different surface wave cloaking techniques

Signal integration and transcriptional regulation of the inflammatory response mediated by the GM-/MCSF signaling axis in human monocytes

In recent years, the macrophage colony-stimulating factor (M-CSF) and granulocyte-macrophage CSF (GM-CSF) cytokines have been identified as opposing regulators of the inflammatory program. However, the two cytokines are simultaneously present in the inflammatory milieu, and it is not clear how cells integrate these signals. In order to understand the regulatory networks associated with the GM/M-CSF signaling axis, we analyzed DNA methylation in human monocytes. Our results indicate that GM-CSF induces activation of the inflammatory program and extensive DNA methylation changes, while M-CSF-polarized cells are in a less differentiated state. This inflammatory program is mediated via JAK2 associated with the GM-CSF receptor and the downstream extracellular signal-regulated (ERK) signaling. However, PI3K signaling is associated with a negative regulatory loop of the inflammatory program and M-CSF autocrine signaling in GM-CSF-polarized monocytes. Our findings describe the regulatory networks associated with the GM/M-CSF signaling axis and how they contribute to the establishment of the inflammatory program associated with monocyte activation.This work was supported by grants from the Plan Nacional de I+D+I 2013– 2016 ISCIII (Institute of Health Carlos III; PI16/01318, PI17/01244, PI17/ 0119, PI16/1900, and PI19/00184); the Gobierno del Principado de Asturias; the PCTI-Plan de Ciencia, Tecnologı´a e Innovacio´ n 2013-2017 (grant IDI/ 2018/144); FEDER ‘‘Funding Program of the European Union’’; the Red Española de Investigación Renal (REDinREN) (RD16/0009/0020, RD016/0009/002, and RD016/0009/001); the Agencia Estatal de Investigación (AEI) (ayuda Juan de la Cierva-Incorporaciόn; IJCI-2017-33347 to R.M.R.); and the Instituto de Salud Carlos III (Contratos Sara Borrell; CD16/00033 to C.H.). CIC bioGUNE support was provided by the Basque Department of Industry, Tourism and Trade (Etortek and Elkartek programs), the Innovation Technology Department of Bizkaia County, the CIBERehd Network, and Spanish MINECO, the Severo Ochoa Excellence Accreditation (SEV-2016-0644