648 research outputs found
Assessment of energy poverty in Andalusian municipalities. Application of a combined indicator to detect priorities
This study aims to assess the energy poverty risk in the municipalities in Andalusia (Spain) to know their existing differences to prioritise the aids in the municipalities with greater needs. For this purpose, a composed indicator is developed. This new indicator is based on the so-called High Energy Requirements (HER) index, where proxy indicators related to the building energy efficiency are joint and where climate severity indicators, together with the income conditions and the gender gap of the population, are included. This new indicator assesses energy poverty globally, joining the indicators related to the characteristics of the dwelling stock with other factors related to energy poverty, such as monetary poverty or gender gap. The results are analysed at a municipal level, so the cases with greater problems both in general terms and those particularly from partial aspects (such as the conservation state or the type of climate) are identified. This characterisation of the phenomenon allows the most appropriate policies to be identified according to the indicators presenting the most unfavourable values, thus constituting a useful tool to prioritise and to implement measures adapted to each municipality’s needs
Estrategia pedagógica apoyada con material educativo digital estudio comparado entre modalidad presencial asistida y educación virtual
Spa: La presente investigación muestra los resultados del análisis de la incidencia de una estrategia pedagógica apoyada con material educativo digital sobre el tema medios de comunicación en un entorno presencial asistido, en comparación con un entorno virtual, con estudiantes de grado quinto de las instituciones UNICAB de Sogamoso y ALEXANDER FLEMING de Bogotá, la
investigación tiene un enfoque mixto de tipo comparativo, planteado desde el análisis
cuantitativo, donde se realizaron encuestas de pre-test y pos-test, los resultados fueron analizados
con la prueba t-student para determinar el efecto en los componentes del tema medios de
comunicación y con el apoyo de la rejilla de observación, se lleva a cabo un análisis cualitativo
para observa las actitudes, valores, trabajo en el aula y hábitos de cooperación, los resultados
fueron analizados con la ayuda del software Atlas. Ti.
El estudio se realizó en la institución educativa Unicab de modalidad virtual, ubicada en el
municipio de Sogamoso en el departamento de Boyacá, y en el colegio Alexander Fleming con
modalidad presencial asistida, en la ciudad Bogotá en el departamento de Cundinamarca. En el
proceso de investigación se tuvo en cuenta la aplicación del modelo TPACK desarrollado por
Mishra y Koehler (2006, 2007), en su base se encuentran tres dimensiones del conocimiento:
contenido, pedagogía y tecnología, se realizó una adaptación incorporando una secuencia
didáctica en seis pasos, basada en la implementación de material educativo digital. Esta
investigación contó con la participación de 22 estudiantes de la modalidad virtual y 9 estudiantes
de la modalidad presencial del grado quinto. Se evidenció que la implementación de la estrategia pedagógica apoyada con material educativo
fue positiva, debido a que se estableció una diferencia favorable comparando los resultados del
pre-test y el post-test, esto se logró evidenciar en cada uno de los tres componentes:
conceptualización, historia e interpretación, en las dos modalidades educativas. En el caso de la modalidad presencial asistida, se evidencia una diferencia significativa y cambios actitudinales en los sujetos objeto de estudio.Eng: The present investigation show the results of the analysis of the impact of a pedagogical strategy supported by educative digital material about the topic of social communication in a assisted inperson environment, compared to a virtual environment with students of fifth grade of the UNICAB of Sogamoso and ALEXANDER FLEMING institutions of Bogotá, the investigation has a mix focus of a comparative type, ba sed in cuantitive analysis where pre-test and post-test surveys were made, the results were analyzed with the t-student test to determine the effect of the
components of the topic "social communication" and with the support of the observation grid, a qualitative analysis is taken place to observe the attitudes, values and work in the classroom as well as habits of cooperation, the results were analyzed with the help of the Atlas Software.
The study was conducted in the educative institution Unicab, located in Sogamoso,
Boyacá and the Alexander Fleming school with the assisted in- person environment in the city of
Bogotá, Cundinamarca. In the investigation process we took into account the application of the
TPACK model developed by Mishra and Koehler (2006, 2007). Their base contains three
dimensions of knowledge: content, pedagogy and technology, an adaption was made a dydactic
sequence in six steps, based on the implementation of digital educative material. This
investigation included the participation of 22 students from the virtual environment and 9
students from the in-person fifth grade.
It was shown that the implementation of the pedagogical strategy supported with
educative material and it was positive, due to that a favorable difference was established
comparing the results of the pre-test and the post-test, this was shown in each of the three
components: conceptualization, history and interpretation in the two educative environments. InBibliografía y webgrafía: páginas 116-124.MaestríaMagister en Educació
Método de extracción de biliproteínas en cultivos de microorganismos utilizando disoluciones de glicerol
Publication number: ES2627007 A1 (26.07.2017)
Application number: P201600100 (26.01.2016)Método de extracción de biliproteínas en cultivos de microorganismos utilizando disoluciones de glicerol. El objeto consiste en obtener extractos de ficobiliproteínas a partir de cultivos de microorganismos (como microalgas o cianobacterias) utilizando un solvente ecológico e inocuo para la salud humana con mayores rendimientos de extracción, menor número de etapas y menores requerimientos energéticos que los actualmente utilizados ya que funciona incluso con biomasa húmeda. Se sumerge la biomasa en una disolución de glicerol a temperatura ambiente o temperatura controlada durante al menos 4 horas, se centrifuga y se obtiene el extracto rico en ficobiliproteínas directamente o bien mediante la adición, previo a la centrifugación, de un pequeño volumen de disolución buffer adecuada (como el buffer de disolución de ácido acético acetato de sodio pH 5.5 250 mM).Universidad de Almerí
Silicification and dolomitization of anhydrite nodules in argillaceous terrestrial deposits: an example of meteoric-dominated diagenesis from the Triassic of central Spain
Cauliflower-shaped nodules are widespread in a single red mudstone bed in
the Buntsandstein (Triassic) facies of the Iberian Range. They consist mostly of
quartz, dolomite and calcite, but other minerals, such as barite, kaolinite and
iron oxyhydroxides, are also present. The nodules are spherical, ovoid or
elongate in shape and range from 1 to 8 cm across. The surface of the nodules
is irregular, and some show a pedogenic coating of microspar. The
sedimentological and petrographic data suggest that the initial anhydrite
nodules formed through a progressive increase in the porewater concentration
of Ca2+ and SO4
2– in a vadose environment, occasionally under the influence of
pedogenic processes. Partial replacement of the anhydrite by megaquartz
occurred under more dilute conditions in the same type of setting, as indicated
by the presence of organic filaments on the quartz crystal surfaces. In type A
nodules, the dissolution of the innermost anhydrite was complete, and
different types of quartz cement filled the porosity. Fracturing and meteoric
cementation by calcite and minor amounts of kaolinite were the latest
processes affecting these nodules. In type B nodules, the dissolution of the
anhydrite was incomplete, inhibiting quartz cementation and enabling later
dolomitization of the anhydrite. Dolomitization appears to have been driven by
sulphate reduction, as indicated by the presence of bacterial bodies within the
dolomite crystals. Dedolomitization and precipitation of barite, kaolinite and
calcite spar cements occurred later under the influence of meteoric solutions.
The nodules may mark the former locations of the water table and provide
evidence for an episode of highly evaporitic conditions throughout wide areas
of the basin. Their occurrence reveals not only a complex diagenetic history but
is also indicative of palaeogeographic and palaeoclimatic conditions
Metals in Cyanobacteria: analysis of the copper, nickel, cobalt and arsenic homeostasis mechanisms
Traces of metal are required for fundamental biochemical processes, such as
photosynthesis and respiration. Cyanobacteria metal homeostasis acquires an important role
because the photosynthetic machinery imposes a high demand for metals, making them a
limiting factor for cyanobacteria, especially in the open oceans. On the other hand, in the
last two centuries, the metal concentrations in marine environments and lake sediments have
increased as a result of several industrial activities. In all cases, cells have to tightly regulate
uptake to maintain their intracellular concentrations below toxic levels. Mechanisms to
obtain metal under limiting conditions and to protect cells from an excess of metals are
present in cyanobacteria. Understanding metal homeostasis in cyanobacteria and the proteins
involved will help to evaluate the use of these microorganisms in metal bioremediation.
Furthermore, it will also help to understand how metal availability impacts primary
production in the oceans. In this review, we will focus on copper, nickel, cobalt and arsenic
(a toxic metalloid) metabolism, which has been mainly analyzed in model cyanobacterium
Synechocystis sp. PCC 6803.info:eu-repo/semantics/publishedVersio
Competing roles of DNA end resection and non-homologous end joining functions in the repair of replication-born double-strand breaks by sister-chromatid recombination
While regulating the choice between homologous recombination and non-homologous end joining (NHEJ) as mechanisms of double-strand break (DSB) repair is exerted at several steps, the key step is DNA end resection, which in Saccharomyces cerevisiae is controlled by the MRX complex and the Sgs1 DNA helicase or the Sae2 and Exo1 nucleases. To assay the role of DNA resection in sister-chromatid recombination (SCR) as the major repair mechanism of spontaneous DSBs, we used a circular minichromosome system for the repair of replication-born DSBs by SCR in yeast. We provide evidence that MRX, particularly its Mre11 nuclease activity, and Sae2 are required for SCR-mediated repair of DSBs. The phenotype of nuclease-deficient MRX mutants is suppressed by ablation of Yku70 or overexpression of Exo1, suggesting a competition between NHEJ and resection factors for DNA ends arising during replication. In addition, we observe partially redundant roles for Sgs1 and Exo1 in SCR, with a more prominent role for Sgs1. Using human U2OS cells, we also show that the competitive nature of these reactions is likely evolutionarily conserved. These results further our understanding of the role of DNA resection in repair of replication-born DSBs revealing unanticipated differences between these events and repair of enzymatically induced DSBs.Ministerio de Ciencia e Innovación BFU2006-05260, BFU2010-16372, CSD2007-015, SAF2010-21017, SAF2010-14877Junta de Andalucía BIO102, CVI4567European Community’s Seventh Framework Programme HEALTH-F2-2010-259893Cancer Research UK C6/A11224, C6946/A14492Wellcome Trust 09209
Methodology to evaluate the state of conservation of historical plasterwork and its polychrome to promote its conservation
This work presents a methodology for the assessment of ancient plasterworks based on
traditional inspection techniques, such as organoleptic tests and chemical characterization, and also
on digital tools, such as photogrammetric surveys, thermography images, and measurement of
ambient conditions with thermohygrometers. This method allows not only defining the alterations
detected and establishing the state of conservation but also digitalizing the plasterworks to preserve
the heritage and replicate the model if necessary (i.e., replacement of a detachment piece), drawing a
hypothesis of the original hidden design of the plasterwork, and conducting a chronological study
about the polychromies used over time. In some cases, the assessment has shown that the liming and
repolychrome interventions to which plasterworks have been subjected and the powdery state of
some areas do not ensure the possibility of the complete polychromy restoration, only its preservation
by taking conservation and maintenance measures
Adquisición de competencias emprendedoras a través de la mentorización de iguales
En este estudio nueve estudiantes de últimos cursos de grado y postgrado han desarrollado competencias emprendedoras mediante la mentorización y evaluación de grupos de estudiantes de primer curso. Cada estudiante de último curso o de postgrado ha llevado a cabo la mentorización de dos grupos de estudiantes en la realización de un trabajo bibliográfico en equipo desarrollado en la asignatura OBLII de primer curso del Grado en Química. Para llevar a cabo dicha mentorización los estudiantes-tutores han realizado entre 6 y 10 reuniones con el equipo durante el semestre y finalmente han evaluado una serie de competencias transversales que suponen el 12% de la calificación de la asignatura. En todo momento ha existido una comunicación entre el estudiante-tutor y el profesor de la asignatura que finalmente corrige el trabajo realizado por los estudiantes. Mediante este sistema, los estudiantes-tutores no solo han sido capaces de transmitir a los estudiantes de nuevo ingreso nuevas metodologías de trabajo, búsqueda de información o gestión del tiempo, sino que han desarrollado una serie de competencias transversales como la capacidad de liderar un equipo, la capacidad y espíritu crítico o la comunicación oral adquiriendo así competencias emprendedoras de gran utilidad para su incorporación al mundo laboral
OBL2013
En este estudio nueve estudiantes de últimos cursos de grado y postgrado han desarrollado competencias emprendedoras mediante la mentorización y evaluación de grupos de estudiantes de primer curso. Cada estudiante de último curso o de postgrado ha llevado a cabo la mentorización de dos grupos de estudiantes en la realización de un trabajo bibliográfico en equipo desarrollado en la asignatura OBLII de primer curso del Grado en Química. Para llevar a cabo dicha mentorización los estudiantes-tutores han realizado entre 6 y 10 reuniones con el equipo durante el semestre y finalmente han evaluado una serie de competencias transversales que suponen el 12% de la calificación de la asignatura. En todo momento ha existido una comunicación entre el estudiante-tutor y el profesor de la asignatura que finalmente corrige el trabajo realizado por los estudiantes. Mediante este sistema, los estudiantes-tutores no solo han sido capaces de transmitir a los estudiantes de nuevo ingreso nuevas metodologías de trabajo, habilidades para la búsqueda de información o como gestionar el tiempo, sino que han desarrollado una serie de competencias transversales como la capacidad de liderar un equipo, la capacidad y espíritu crítico o la comunicación oral adquiriendo así competencias emprendedoras de gran utilidad para su incorporación al mundo laboral
N7-methylguanosine methylation of tRNAs regulates survival to stress in cancer
Tumour progression and therapy tolerance are highly regulated and complex processes largely dependent on the plasticity of cancer cells and their capacity to respond to stress. The higher plasticity of cancer cells highlights the need for identifying targetable molecular pathways that challenge cancer cell survival. Here, we show that
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