3,308 research outputs found
Direct in-vial collection for liquid-scintillation assay of carbon-14 and tritium
Dissolution of biological materials combines the simplicity of oxygen-flask combustion with the reproducibility and purity of the final product, and convenience of direct in-vial collection of the sample by the sealed-tube method. It assures quantitative and reproducible recoveries
Combustion method for assay of biological materials labeled with carbon-14 or tritium, or double-labeled
Dry catalytic combustion at high temperatures is used for assaying biological materials labeled carbon-14 and tritium, or double-labeled. A modified oxygen-flask technique is combined with standard vacuum-line techniques and includes convenience of direct in-vial collection of final combustion products, giving quantitative recovery of tritium and carbon-14
Crop moisture estimation over the southern Great Plains with dual polarization 1.66 centimeter passive microwave data from Nimbus 7
Moisture content of snow-free, unfrozen soil is inferred using passive microwave brightness temperatures from the scanning multichannel microwave radiometer (SMMR) on Nimbus-7. Investigation is restricted to the two polarizations of the 1.66 cm wavelength sensor. Passive microwave estimates of soil moisture are of two basic categories; those based upon soil emissivity and those based upon the polarization of soil emission. The two methods are compared and contrasted through the investigation of 54 potential functions of polarized brightness temperatures and, in some cases, ground-based temperature measurements. Of these indices, three are selected for the estimated emissivity, the difference between polarized brightness temperatures, and the normalized polarization difference. Each of these indices is about equally effective for monitoring soil moisture. Using an antecedent precipitation index (API) as ground control data, temporal and spatial analyses show that emissivity data consistently give slightly better soil moisture estimates than depolarization data. The difference, however, is not statistically significant. It is concluded that polarization data alone can provide estimates of soil moisture in areas where the emissivity cannot be inferred due to nonavailability of surface temperature data
Global services and support for children with developmental delays and disabilities: Bridging research and policy gaps
Summary: 1. The United Nations Sustainable Development Goals and the UN Convention on the Rights of the Child (CRC) envision an inclusive society in which health and education contribute to the well-being of all. To achieve this vision, children with developmental delays and behavioral, cognitive, mental, and neurological disabilities need greater access to health care, early childhood care and development services, and education.
2. Improved population-level detection, alongside screening, assessment, and linkage to evidence-based, intersectoral services in the first years of life, can help maximize capabilities and increase the chances of social inclusion for children with developmental delays and disabilities.
3. Educational programs for children with delays and disabilities whose service delivery structure supports the ability of parents to work should be encouraged so that parents can participate in achieving children’s educational goals while also meeting their financial needs.
4. Parents and caregivers who receive training in psychosocial interventions and ongoing support can help children with delays and disabilities thrive in family contexts.
5. Family mental health influences the developmental trajectory of children. Ensuring that parents and caregivers have access to affordable, quality mental health services helps to prevent poor outcomes for children.
6. Rigorous evaluation, continuous quality improvement, and regular monitoring of the programmatic outcomes of services and policy approaches targeting children and caregivers would inform their implementation and serve to disseminate lessons learned from successful policy and program implementation
Organics in comet 67P – a first comparative analysis of mass spectra from ROSINA–DFMS, COSAC and Ptolemy
The ESA Rosetta spacecraft followed comet 67P at a close distance for more than 2 yr. In addition, it deployed the lander Philae on to the surface of the comet. The (surface) composition of the comet is of great interest to understand the origin and evolution of comets. By combining measurements made on the comet itself and in the coma, we probe the nature of this surface material and compare it to remote sensing observations. We compare data from the double focusing mass spectrometer (DFMS) of the ROSINA experiment on ESA's Rosetta mission and previously published data from the two mass spectrometers COSAC (COmetary Sampling And Composition) and Ptolemy on the lander. The mass spectra of all three instruments show very similar patterns of mainly CHO-bearing molecules that sublimate at temperatures of 275 K. The DFMS data also show a great variety of CH-, CHN-, CHS-, CHO2- and CHNO-bearing saturated and unsaturated species. Methyl isocyanate, propanal and glycol aldehyde suggested by the earlier analysis of the measured COSAC spectrum could not be confirmed. The presence of polyoxymethylene in the Ptolemy spectrum was found to be unlikely. However, the signature of the aromatic compound toluene was identified in DFMS and Ptolemy data. Comparison with remote sensing instruments confirms the complex nature of the organics on the surface of 67P, which is much more diverse than anticipated
Wigs, disguises and child's play : solidarity in teacher education
It is generally acknowledged that much contemporary education takes place within a dominant audit culture, in which accountability becomes a powerful driver of educational practices. In this culture both pupils and teachers risk being configured as a means to an assessment and target-driven end: pupils are schooled within a particular paradigm of education. The article discusses some ethical issues raised by such schooling, particularly the tensions arising for teachers, and by implication, teacher educators who prepare and support teachers for work in situations where vocational aims and beliefs may be in in conflict with instrumentalist aims. The article offers De Certeau’s concept of ‘la perruque’ to suggest an opening to playful engagement for human ends in education, as a way of contending with and managing the tensions generated. I use the concept to recover a concept of solidarity for teacher educators and teachers to enable ethical teaching in difficult times
ICF-based Functional Components and Contextual Factors as Correlates of Perceived Quality of Life for Youth With Chronic Conditions
Purpose: To explore International Classification of Functioning, Disability and Health (ICF)-based functional components and contextual factors associated with perceived quality of life (QOL) for youth with chronic conditions from the perspective of youth and parents.
Method: Baseline data were obtained from a longitudinal study examining predictors of changes in perceived QOL for youth with chronic conditions. 439 youth aged 11–17 (and one of their parents) completed a questionnaire. Standardized tools were used to measure youth functioning, contextual factors and perceived QOL. Multivariate linear regression analyses, controlling for socio-demographic and health information, were conducted to explore correlations among youth functioning/contextual factors and youth and parent perceptions of youth QOL. Results: Significant (p0.05) negative correlates with both youth and parent perceptions of youth QOL included pain/other physical symptoms and emotional symptoms. Significant factors positively correlated with youth and parent perceptions of youth QOL included school productivity and spirituality. Other significant positive correlates of youth perspectives were family social support and school belongingness/safety. Family functioning was positively correlated, and youth social anxiety and environmental barriers were negatively correlated, with parent perceptions of youth QOL.
Conclusions: This study provides preliminary evidence of factors upon which services aimed at improving perceived QOL of youth with chronic conditions could be based
Extracts of Feijoa Inhibit Toll-Like Receptor 2 Signaling and Activate Autophagy Implicating a Role in Dietary Control of IBD
Inflammatory bowel disease (IBD) is a heterogeneous chronic inflammatory disease affecting the gut with limited treatment success for its sufferers. This suggests the need for better understanding of the different subtypes of the disease as well as nutritional interventions to compliment current treatments. In this study we assess the ability of a hydrophilic feijoa fraction (F3) to modulate autophagy a process known to regulate inflammation, via TLR2 using IBD cell lines
Numerical Relativity: A review
Computer simulations are enabling researchers to investigate systems which
are extremely difficult to handle analytically. In the particular case of
General Relativity, numerical models have proved extremely valuable for
investigations of strong field scenarios and been crucial to reveal unexpected
phenomena. Considerable efforts are being spent to simulate astrophysically
relevant simulations, understand different aspects of the theory and even
provide insights in the search for a quantum theory of gravity. In the present
article I review the present status of the field of Numerical Relativity,
describe the techniques most commonly used and discuss open problems and (some)
future prospects.Comment: 2 References added; 1 corrected. 67 pages. To appear in Classical and
Quantum Gravity. (uses iopart.cls
Low field vortex dynamics over seven time decades in a Bi_2Sr_2CaCu_2O_{8+\delta} single crystal for temperatures 13 K < T < 83 K
Using a custom made dc-SQUID magnetometer, we have measured the time
relaxation of the remanent magnetization M_rem of a Bi_2Sr_2CaCu_2O_{8+\delta}
single crystal from the fully critical state for temperatures 13 K < T < 83 K.
The measurements cover a time window of seven decades 10^{-2} s < t < 10^5 s,
so that the current density j can be studied from values very close to j_c down
to values considerably smaller than j_c. From the data we have obtained: (i)
the flux creep activation barriers U as a function of current density j, (ii)
the current-voltage characteristics E(j) in a typical range of 10^{-7} V/cm to
10^{-15} V/cm, and (iii) the critical current density j_c(0) at T = 0. Three
different regimes of vortex dynamics are observed: For temperatures T < 20 K
the activation barrier U(j) is logarithmic, no unique functional dependence
U(j) could be found for the intermediate temperature interval 20 K < T < 40 K,
and finally for T > 40 K the activation barrier U(j) follows a power-law
behavior with an exponent mu = 0.6. From the analysis of the data within the
weak collective pinning theory for strongly layered superconductors, it is
argued that for temperatures T < 20 K pancake-vortices are pinned individually,
while for temperatures T > 40 K pinning involves large collectively pinned
vortex bundles. A description of the vortex dynamics in the intermediate
temperature interval 20 K < T < 40 K is given on the basis of a qualitative low
field phase diagram of the vortex state in Bi_2Sr_2CaCu_2O_{8+\delta}. Within
this description a second peak in the magnetization loop should occur for
temperatures between 20 K and 40 K, as it has been observed in several
magnetization measurements in the literature.Comment: 12 pages, 10 figure
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