5 research outputs found
Until we met I never knew the joy of living, [first line of chorus]
No full textPerformance Medium: Piano, Voice and Chord
In vitro detection of superoxide anions released from cancer cells based on potassium-doped carbon nanotubes–ionic liquid composite gels
No full textMass Spectrometry Based Glycoproteomics—From a Proteomics Perspective*
No full textGlycosylation is one of the most important and common forms of protein post-translational modification that is involved in many physiological functions and biological pathways. Altered glycosylation has been associated with a variety of diseases, including cancer, inflammatory and degenerative diseases. Glycoproteins are becoming important targets for the development of biomarkers for disease diagnosis, prognosis, and therapeutic response to drugs. The emerging technology of glycoproteomics, which focuses on glycoproteome analysis, is increasingly becoming an important tool for biomarker discovery. An in-depth, comprehensive identification of aberrant glycoproteins, and further, quantitative detection of specific glycosylation abnormalities in a complex environment require a concerted approach drawing from a variety of techniques. This report provides an overview of the recent advances in mass spectrometry based glycoproteomic methods and technology, in the context of biomarker discovery and clinical application
