Components of AR-quivers for string algebras of type C˜ and a conjecture by Geiss-Leclerc-Schröer

We study modules of certain string algebras, which are referred to as of affine type C˜. We introduce minimal string modules and apply them to explicitly describe components of the Auslander-Reiten quivers of the string algebras and τ-locally free modules defined by Geiss-Lerclerc-Schröer. In particular, we show that an indecomposable module is τ-locally free if and only if it is preprojective, or preinjective or regular in a tube. As an application, we prove Geiss-Leclerc-Schröer's conjecture on the correspondence between positive roots of type C˜ and τ-locally free modules of the corresponding string algebras. Furthermore, given a positive root α, we show that if α is real, then there is a unique τ-locally free module M (up to isomorphism) with rank_M=α; otherwise there are families of τ-locally free modules with rank_M=α.</p

Components of AR-quivers for string algebras of type C˜ and a conjecture by Geiss-Leclerc-Schröer

We study modules of certain string algebras, which are referred to as of affine type C˜. We introduce minimal string modules and apply them to explicitly describe components of the Auslander-Reiten quivers of the string algebras and τ-locally free modules defined by Geiss-Lerclerc-Schröer. In particular, we show that an indecomposable module is τ-locally free if and only if it is preprojective, or preinjective or regular in a tube. As an application, we prove Geiss-Leclerc-Schröer's conjecture on the correspondence between positive roots of type C˜ and τ-locally free modules of the corresponding string algebras. Furthermore, given a positive root α, we show that if α is real, then there is a unique τ-locally free module M (up to isomorphism) with rank_M=α; otherwise there are families of τ-locally free modules with rank_M=α.</p

Report drawn up on behalf of the Committee on Economic and Monetary Affairs on the possible loan from the OPEC countries to the Federal Republic of Germany and to France. EP Working Documents 1982-83, Document 1-284/82, 4 June 1982

Abstract Background Hand, foot, and mouth disease (HFMD) has become an emerging infectious disease in China in the last decade. There has been evidence that meteorological factors can influence the HFMD incidence, and understanding the mechanisms can help prevent and control HFMD. Methods HFMD incidence data and meteorological data in Minhang District, Shanghai were obtained for the period between 2009 and 2015. Distributed lag non-linear models (DLNMs) were utilized to investigate the impact of meteorological factors on HFMD incidence after adjusting for potential confounders of long time trend, weekdays and holidays. Results There was a non-linear relationship between temperature and HFMD incidence, the RR of 5th percentile compared to the median is 0.836 (95% CI: 0.671–1.042) and the RR of 95th percentile is 2.225 (95% CI: 1.774–2.792), and the effect of temperature varied across age groups. HFMD incidence increased with increasing average relative humidity (%) (RR = 1.009, 95% CI: 1.005–1.015) and wind speed (m/s) (RR = 1.197, 95% CI: 1.118–1.282), and with decreasing daily rainfall (mm) (RR = 0.992, 95% CI: 0.987–0.997) and sunshine hours (h) (RR = 0.966, 95% CI: 0.951–0.980). Conclusions There were significant relationships between meteorological factors and childhood HFMD incidence in Minhang District, Shanghai. This information can help local health agencies develop strategies for the control and prevention of HFMD under specific climatic conditions

Electronic Health Record-Based Screening for Major Cancers: A 9-Year Experience in Minhang District of Shanghai, China

Background: An electronic health record (e-HR) system has been developed in Minhang District of Shanghai, China, since 2005, making it convenient for local health institutions to provide integrative and comprehensive health care and management for major diseases.Methods: In 2008, an e-HR-based cancer prevention program was initiated to screen multiple cancers, including colorectal, gastric, liver, lung, cervical, and breast cancers, and provide subsequent health education and health management to cancer patients and high-risk individuals. This study was designed in prospective analysis, based on the constructive analysis of key information, observation of cancer screening and healthcare processes and organizations, and stages of cancers detected by the e-HR-based programs.Results: From 2008 to 2016, health education was conducted for over 5 million attendances, and more than 3 million screening tests were performed for eligible residents over 40 years old. A total of 2,948 cancer cases were detected, accounting for 13.3% of all newly diagnosed cancers in the district during the 9-year period. Thirty point seven percent detected cancer cases were at the early stage, significantly higher than the 22.9% in cases identified by e-HR-based follow-up and 13.8% in cases diagnosed due to signs or symptoms. More than 136,000 residents were identified as individuals at high risk of cancer and subject to sustainable clinical follow-up and health management.Conclusions: The successful application of e-HR system in cancer prevention and control in Minhang district of Shanghai, China, implies that the system may act as an extendable and sustainable infrastructure for comprehensive health care and services for a broad spectrum of diseases and health events

TELEX HEBDOMADAIRE NR 95 DU 17.09.82 DESTINE A L'ENSEMBLE DES DELEGATIONS EXTERIEURES ET BUREAUX DE PRESS ET D'INFORMATION INDEPENDANTS DANS LES PAYS TIERS = WEEKLY MEMO NO. 95 FOR 17.09.82 TO FOREIGN DELEGATIONS AND PRESS BUREAUS OF THIRD COUNTRIES

<p>High-performance liquid chromatography (HPLC) results of (A) commercial surfactin sample, and (B) our extract surfactin of <i>B</i>. <i>subtilis</i> HH2 in LB medium. There were three main peaks (Peak A-C) of the extract and the surfactin standard in the same location.</p

Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors

Background Suicide is a leading cause of death worldwide, and nonfatal suicide attempts, which occur far more frequently, are a major source of disability and social and economic burden. Both have substantial genetic etiology, which is partially shared and partially distinct from that of related psychiatric disorders. Methods We conducted a genome-wide association study (GWAS) of 29,782 suicide attempt (SA) cases and 519,961 controls in the International Suicide Genetics Consortium (ISGC). The GWAS of SA was conditioned on psychiatric disorders using GWAS summary statistics via multitrait-based conditional and joint analysis, to remove genetic effects on SA mediated by psychiatric disorders. We investigated the shared and divergent genetic architectures of SA, psychiatric disorders, and other known risk factors. Results Two loci reached genome-wide significance for SA: the major histocompatibility complex and an intergenic locus on chromosome 7, the latter of which remained associated with SA after conditioning on psychiatric disorders and replicated in an independent cohort from the Million Veteran Program. This locus has been implicated in risk-taking behavior, smoking, and insomnia. SA showed strong genetic correlation with psychiatric disorders, particularly major depression, and also with smoking, pain, risk-taking behavior, sleep disturbances, lower educational attainment, reproductive traits, lower socioeconomic status, and poorer general health. After conditioning on psychiatric disorders, the genetic correlations between SA and psychiatric disorders decreased, whereas those with nonpsychiatric traits remained largely unchanged. Conclusions Our results identify a risk locus that contributes more strongly to SA than other phenotypes and suggest a shared underlying biology between SA and known risk factors that is not mediated by psychiatric disorders.Peer reviewe

Genome-wide comprehensive analysis of transcriptomes and small RNAs offers insights into the molecular mechanism of alkaline stress tolerance in a citrus rootstock

Molecular biology: Rooting out alkaline resistance mechanisms in citrus trees The ability of citrus trees to tolerate alkaline soils may hinge upon plant hormones called auxins which regulate root growth. The discovery could aid the development of more resilient rootstocks. Alkaline stress, caused by e.g. industrial run-off, is a growing problem worldwide because it reduces the growth and survival of crops – including the most widely used citrus rootstock in China, Poncirus trifoliata. To better understand the mechanisms underpinning tolerance to soil alkalinity, Hualin Yi at Huazhong Agricultural University in Wuhan, China, and colleagues used next-generation sequencing to profile the transcription products of P. trifolata seedlings and those of an alkaline-tolerant rootstock, Ziyang xiangcheng, when they were grown in three different nutrient solutions. Auxin homeostasis appears to be a key element of citrus adaption to alkaline stress, they found - probably by encouraging lateral root branching

Upper Limb Rehabilitation Robot Powered by PAMs Cooperates with FES Arrays to Realize Reach-to-Grasp Trainings

The reach-to-grasp activities play an important role in our daily lives. The developed RUPERT for stroke patients with high stiffness in arm flexor muscles is a low-cost lightweight portable exoskeleton rehabilitation robot whose joints are unidirectionally actuated by pneumatic artificial muscles (PAMs). In order to expand the useful range of RUPERT especially for patients with flaccid paralysis, functional electrical stimulation (FES) is taken to activate paralyzed arm muscles. As both the exoskeleton robot driven by PAMs and the neuromuscular skeletal system under FES possess the highly nonlinear and time-varying characteristics, iterative learning control (ILC) is studied and is taken to control this newly designed hybrid rehabilitation system for reaching trainings. Hand function rehabilitation refers to grasping. Because of tiny finger muscles, grasping and releasing are realized by FES array electrodes and matrix scan method. By using the surface electromyography (EMG) technique, the subject’s active intent is identified. The upper limb rehabilitation robot powered by PAMs cooperates with FES arrays to realize active reach-to-grasp trainings, which was verified through experiments

Comprehensive analysis provides insights into Ziyang xiangcheng (Citrus junos Sieb.) tolerance of alkalinity stress

Alkaline soil is one of the major problems affecting the development of the citrus industry. Ziyang xiangcheng (Citrus junos Sieb. ex Tanaka) (Cj) is an alkalinity stress-tolerant citrus rootstock. In this study, two citrus rootstocks (Cj and Poncirus trifoliata (L.) Raf.) (Pt)) and one navel orange scion ('Lane Late' navel orange (Citrus sinensis (L.) Osb.) (LL)) were used. The root, stem and leaf tissues of grafted materials Cj + LL and Pt + LL grown in calcareous soil were used to identify genes and pathways that are responsive to alkalinity stress using comparative transcriptomics. Seedlings of Cj and Pt cultured in nutrient solutions at three pH grades were used to perform a supplemental experiment. A comprehensive analysis of the RNA-seq data, physiology, biochemistry, agronomic traits and mineral elements of the Cj + LL, Pt + LL, Cj and Pt materials revealed several candidate pathways and genes that were highly regulated under alkalinity stress. The data suggest that the jasmonate pathway may play crucial roles in tolerance to alkalinity stress in Cj by interacting with other plant hormones, lignin biosynthesis and the ROS scavenging system. These results provide new clues for future investigations of the mechanisms underlying the tolerance of citrus to alkalinity stress

Application of Network Scale Up Method in the Estimation of Population Size for Men Who Have Sex with Men in Shanghai, China.

Men who have sex with men (MSM) are at high risk of HIV infection. For developing proper interventions, it is important to know the size of MSM population. However, size estimation of MSM populations is still a significant public health challenge due to high cost, hard to reach and stigma associated with the population.We aimed to estimate the social network size (c value) in general population and the size of MSM population in Shanghai, China by using the net work scale-up method.A multistage random sampling was used to recruit participants aged from 18 to 60 years who had lived in Shanghai for at least 6 months. The "known population method" with adjustment of backward estimation and regression model was applied to estimate the c value. And the MSM population size was further estimated using an adjusted c value taking into account for the transmission effect through social respect level towards MSM.A total of 4017 participants were contacted for an interview, and 3907 participants met the inclusion criterion. The social network size (c value) of participants was 236 after adjustment. The estimated size of MSM was 36354 (95% CI: 28489-44219) for the male Shanghaies aged 18 to 60 years, and the proportion of MSM among the total male population aged 18 to 60 years in Shanghai was 0.28%.We employed the network scale-up method and used a wide range of data sources to estimate the size of MSM population in Shanghai, which is useful for HIV prevention and intervention among the target population