alphabeta sequence of F is IS31

Previous studies have shown that there is a deoxyribonucleic acid (DNA) segment, of length 1.3 kb and denoted as the alphabeta sequence, which occurs twice on the F plasmid at corrdinates 93.2 to 94.5/OF kb and 13.7 to 15.0F kb. In the present investigation, heteroduplexes were prepared between a phage DNA carrying the insertion sequence IS3 and suitable F-prime DNAs. The hybrids formed show that IS3 is the same as alphabeta. This result plus previous studies support the view that: (i) the insertion sequence IS2 and IS3 occur on F and, in multiple copies, on the main bacterial chromosome of Escherichia coli K-12; and (ii)these IS sequences on the main bacterial chromosomes are hot spots for Hfr formation by reciprocal recombination with the corresponding sequences of F

A limited feedback scheme for massive MIMO systems based on principal component analysis

Massive multiple-input multiple-output (MIMO) is becoming a key technology for future 5G cellular networks. Channel feedback for massive MIMO is challenging due to the substantially increased dimension of the channel matrix. This motivates us to explore a novel feedback reduction scheme based on the theory of principal component analysis (PCA). The proposed PCA-based feedback scheme exploits the spatial correlation characteristics of the massive MIMO channel models, since the transmit antennas are deployed compactly at the base station (BS). In the proposed scheme, the mobile station (MS) generates a compression matrix by operating PCA on the channel state information (CSI) over a long-term period, and utilizes the compression matrix to compress the spatially correlated high-dimensional CSI into a low-dimensional representation. Then, the compressed low-dimensional CSI is fed back to the BS in a short-term period. In order to recover the high-dimensional CSI at the BS, the compression matrix is refreshed and fed back from MS to BS at every long-term period. The information distortion of the proposed scheme is also investigated and a closed-form expression for an upper bound to the normalized information distortion is derived. The overhead analysis and numerical results show that the proposed scheme can offer a worthwhile tradeoff between the system capacity performance and implementation complexity including the feedback overhead and codebook search complexit

Anisotropic Neutron Spin Resonance in Superconducting BaFe1.9_{1.9}Ni0.1_{0.1}As2_2

We use polarized inelastic neutron scattering to show that the neutron spin resonance below $T_c$ in superconducting BaFe$_{1.9}$Ni$_{0.1}$As$_2$ ($T_c=20$ K) is purely magnetic in origin. Our analysis further reveals that the resonance peak near 7~meV only occurs for the planar response. This challenges the common perception that the spin resonance in the pnictides is an isotropic triplet excited state of the singlet Cooper pairs, as our results imply that only the $S_{001}=\pm1$ components of the triplet are involved

Impurity-induced Local Density of States in a D-wave Superconductor Carrying a Supercurrent

The local density of states (LDOS) and its Fourier component induced by a unitary impurity in a supercurrent-carrying d-wave superconductor are investigated. Both of these quantities possess a reflection symmetry about the line passing through the impurity site and along the supercurrent if it is applied along the antinodal or nodal direction. With increasing supercurrent, both the coherence and resonant peaks in the LDOS are suppressed and slightly broadened. Under a supercurrent along the antinodal direction, the coherence peaks split into double peaks. The modulation wavevectors associated with elastic scatterings of quasiparticles by the defect from one constant-energy piece of the Fermi surface to another are displayed as bright or dark spots in the Fourier space of the LDOS image, and they may be suppressed or enhanced, and shifted depending on the applied current and the bias voltage.Comment: 5 pages, 6 figure

Brief of Scholars of the History and Original Meaning of the Fourth Amendment as Amici Curiae in Support of Petitioner, Carpenter v. United States, No. 16-402 (U.S. Aug. 14, 2017)

Obtaining and examining cell site location records to find a person is a “search” in any normal sense of the word — a search of documents and a search for a person and her personal effects. It is therefore a “search” within the meaning of the Fourth Amendment in that it constitutes “examining,” “exploring,” “looking through,” “inquiring,” “seeking,” or “trying to find.” Nothing about the text of the Fourth Amendment, or the historical backdrop against which it was adopted, suggests that “search” should be construed more narrowly as, for example, intrusions upon subjectively manifested expectations of privacy that society is prepared to recognize as reasonable.Entrusting government agents with unfettered discretion to conduct searches using cell site location information undermines Fourth Amendment rights. The Amendment guarantees “[t]he right of the people to be secure in their persons, houses, papers, and effects, against unreasonable searches.” The Framers chose that language deliberately. It reflected the insecurity they suffered at the hands of “writs of assistance,” a form of general warrant that granted state agents broad discretion to search wherever they pleased. Such arbitrary power was “unreasonable” to the Framers, being “against the reason of the common law,” and it was intolerable because of its oppressive impact on “the people” as a whole. As emphasized in one of the seminal English cases that inspired the Amendment, this kind of general power to search was “totally subversive of the liberty of the subject.” James Otis’s famous speech denouncing a colonial writ of assistance similarly condemned those writs as “the worst instrument of arbitrary power,” placing “the liberty of every man in the hands of every petty officer.” Thus, although those who drafted and ratified the Fourth Amendment could not have anticipated cellphone technology, they would have recognized the dangers inherent in any state claim of unlimited authority to conduct searches for evidence of criminal activity. Cell site location information provides insight into where we go and what we do. Because this information is constantly generated and can be retrieved by the government long after the activities it memorializes have taken place, unfettered government access to cell site location information raises the specter of general searches and undermines the security of “the people.

Gene expression profiling of lymphoblastoid cell lines from monozygotic twins discordant in severity of autism reveals differential regulation of neurologically relevant genes

BACKGROUND: The autism spectrum encompasses a set of complex multigenic developmental disorders that severely impact the development of language, non-verbal communication, and social skills, and are associated with odd, stereotyped, repetitive behavior and restricted interests. To date, diagnosis of these neurologically based disorders relies predominantly upon behavioral observations often prompted by delayed speech or aberrant behavior, and there are no known genes that can serve as definitive biomarkers for the disorders. RESULTS: Here we demonstrate, for the first time, that lymphoblastoid cell lines from monozygotic twins discordant with respect to severity of autism and/or language impairment exhibit differential gene expression patterns on DNA microarrays. Furthermore, we show that genes important to the development, structure, and/or function of the nervous system are among the most differentially expressed genes, and that many of these genes map closely in silico to chromosomal regions containing previously reported autism candidate genes or quantitative trait loci. CONCLUSION: Our results provide evidence that novel candidate genes for autism may be differentially expressed in lymphoid cell lines from individuals with autism spectrum disorders. This finding further suggests the possibility of developing a molecular screen for autism based on expressed biomarkers in peripheral blood lymphocytes, an easily accessible tissue. In addition, gene networks are identified that may play a role in the pathophysiology of autism

Lyman Alpha Galaxies: Primitive, Dusty or Evolved Galaxies?

We present stellar population modeling results for 10 newly discovered Lyman alpha emitting galaxies (LAEs), as well as four previously known LAEs at z ~ 4.5 in the Chandra Deep Field - South. We fit stellar population models to these objects in order to learn specifically if there exists more than one class of LAE. Past observational and theoretical evidence has shown that while many LAEs appear to be young, they may be much older, with Lyman alpha EWs enhanced due to resonant scattering of Lyman alpha photons in a clumpy interstellar medium (ISM). Our results show a large range of stellar population age (3 - 500 Myr), stellar mass (1.6 x 10^8 - 5.0 x 10^10 Msol) and dust extinction (A_1200 = 0.3 - 4.5 mag), broadly consistent with previous studies. With such a large number of individually analyzed objects, we have looked at the distribution of stellar population ages in LAEs for the first time, and we find a very interesting bimodality, in that our objects are either very young ( 450 Myr). This bimodality may be caused by dust, and it could explain the Lyman alpha duty cycle which has been proposed in the literature. We find that eight of the young objects are best fit with a clumpy ISM. We find that dust geometry appears to play a large role in shaping the SEDs that we observe, and that it may be a major factor in the observed Lyman alpha equivalent width distribution in high redshift Lyman alpha galaxies, although other factors (i.e. outflows) may be in play. We conclude that 12 out of our 14 LAEs are dusty star-forming galaxies, with the other two LAEs being evolved galaxies.Comment: Replaced with ApJ accepted versionl. 20 pages, 10 figures, four table

Spectroscopic Confirmation of Faint Lyman Break Galaxies at Redshifts Four and Five in the Hubble Ultra Deep Field

We present the faintest spectroscopically confirmed sample of redshift four and five Lyman break galaxies to date. The sample is based on slitless grism spectra of the Hubble Ultra Deep Field region from the GRAPES (Grism ACS Program for Extragalactic Science) and PEARS (Probing Evolution and Reionization Spectroscopically) projects, using the G800L grism on the HST Advanced Camera for Surveys. We report here confirmations of 39 galaxies, pre-selected as candidate Lyman break galaxies using photometric selection criteria. We compare a "traditional" V-dropout selection to a more liberal one (with V-i > 0.9), and find that the traditional criteria are about 64% complete and 81% reliable. We also study the Lyman alpha emission properties of our sample. We find that Lyman alpha emission is detected in about 1/4 of the sample, and that our broad-band color selected sample includes 55% of previously published line-selected Lyman alpha sources. Finally, we examine our stacked 2D spectra. We demonstrate that strong, spatially extended (arcsecond scale) Lyman alpha emission is not a generic property of these Lyman break galaxies, but that a modest extension of the Lyman alpha photosphere (compared to the starlight) may be present in those galaxies with prominent Lyman alpha emission.Comment: Submitted to The Astrophysical Journal. Reduced spectra from both GRAPES and PEARS are available from STScI, at http://www.stsci.edu/science/grapes/ and at http://archive.stsci.edu/prepds/pears

The Symmetries of the Order Parameters for Pairing and Phase Coherence in Hole-Doped Cuprates

The symmetries of the order parameter (OP) responsible for pairing and the OP responsible for phase coherence in hole-doped cuprates are discussed. We analyze angle-resolved tunneling, ARPES, Raman scattering and torque measurements performed on hole-doped cuprates. We conclude that, most likely, the OP responsible for phase coherence has the d-wave symmetry whereas the OP responsible for pairing has an anisotropic s-wave symmetry.Comment: 18 pages including 6 figure