Mercury in the environs of the north slope of Alaska

The analysis of Greenland ice suggests that the flux of mercury from the continents to the atmosphere has increased in recent times, perhaps partly as a result of the many of man’s activities that effect an alteration of terrestrial surfaces. Upon the exposure of fresh crustal matter, the natural outgassing of mercury vapor from the earth’s surface could be enhanced. Accordingly, mercury was measured in a variety of environmental materials gathered from the North Slope of Alaska to provide background data prior to the anticipated increase of activity in this environment. The materials were collected during the U. S. Coast Guard WEBSEC 72-73 cruises as well as through the facilities provided by Naval Arctic Research Laboratory in the spring of 1973. The method of measurement depended upon radioactivation of mercury with neutrons and the subsequent quantification of characteristic gamma radiations after radiochemical purification. Mercury concentrations in seawater at several locations in the vicinity of 151°W, 71°N averaged 20 parts per trillion. The waters from all stations east of this location showed a significantly smaller concentration. This difference may relate to penetration o f Bering- Chukchi Sea water into the southern Beaufort Sea to 151°W. Marine sediments on the shelf and slope between 143°W and 153°W contained about 100 parts per billion mercury, except for those on the continental shelf between Barter Island and the Canning River, where the concentration was less than half this value. These results are consistent with sediment input from the respective rivers when their mercury content and mineralogy are considered. The mercury content of river waters was 18 ppt and in reasonable agreement with the average of snow samples (13 ppt). The burden of mercury in plankton was 37 ppb.This work was supported by the office of Naval Research under grant N R 083-290

The Reaction of Potassium Amide in Liquid Ammonia with Diarylbromethenes

The behavior of certain diarylchloroethenes with potassium amide in liquid ammonia has been reported previously. A rapid reaction occurs and the ethenes are changed with the loss of hydrochloric acid to tolanes. Thus 1, 1-di-p-tolyl-2-chloroethene forms p. p\u27-dimethyltolane. A series of such para substituted compounds was studied and as anticipated only symmetrical tolanes were obtained

Uniformity in the Wiener-Wintner theorem for nilsequences

We prove a uniform extension of the Wiener-Wintner theorem for nilsequences due to Host and Kra and a nilsequence extension of the topological Wiener-Wintner theorem due to Assani. Our argument is based on (vertical) Fourier analysis and a Sobolev embedding theorem.Comment: v3: 18 p., proof that the cube construction produces compact homogeneous spaces added, measurability issues in the proof of Theorem 1.5 addressed. We thank the anonymous referees for pointing out these gaps in v

Measurement of the dark matter velocity anisotropy in galaxy clusters

The internal dynamics of a dark matter structure may have the remarkable property that the local temperature in the structure depends on direction. This is parametrized by the velocity anisotropy beta which must be zero for relaxed collisional structures, but has been shown to be non-zero in numerical simulations of dark matter structures. Here we present a method to infer the radial profile of the velocity anisotropy of the dark matter halo in a galaxy cluster from X-ray observables of the intracluster gas. This non-parametric method is based on a universal relation between the dark matter temperature and the gas temperature which is confirmed through numerical simulations. We apply this method to observational data and we find that beta is significantly different from zero at intermediate radii. Thus we find a strong indication that dark matter is effectively collisionless on the dynamical time-scale of clusters, which implies an upper limit on the self-interaction cross-section per unit mass sigma/m < 1 cm2/g. Our results may provide an independent way to determine the stellar mass density in the central regions of a relaxed cluster, as well as a test of whether a cluster is in fact relaxed.Comment: 10 pages, 8 figures, submitted to Ap

Might we eventually understand the origin of the dark matter velocity anisotropy?

The density profile of simulated dark matter structures is fairly well-established, and several explanations for its characteristics have been put forward. In contrast, the radial variation of the velocity anisotropy has still not been explained. We suggest a very simple origin, based on the shapes of the velocity distributions functions, which are shown to differ between the radial and tangential directions. This allows us to derive a radial variation of the anisotropy profile which is in good agreement with both simulations and observations. One of the consequences of this suggestion is that the velocity anisotropy is entirely determined once the density profile is known. We demonstrate how this explains the origin of the \gamma-\beta relation, which is the connection between the slope of the density profile and the velocity anisotropy. These findings provide us with a powerful tool, which allows us to close the Jeans equations.Comment: 10 pages, 7 figures, subm to ap

A detailed statistical analysis of the mass profiles of galaxy clusters

The distribution of mass in the halos of galaxies and galaxy clusters has been probed observationally, theoretically, and in numerical simulations. Yet there is still confusion about which of several suggested parameterized models is the better representation, and whether these models are universal. We use the temperature and density profiles of the intracluster medium as measured by X-ray observations of 11 relaxed galaxy clusters to investigate mass models for the halo using a thorough Bayesian statistical analysis. We make careful comparisons between two- and three-parameter models, including the issue of a universal third parameter. We find that, of the two-parameter models, the NFW is the best representation, but we also find moderate statistical evidence that a generalized three-parameter NFW model with a freely varying inner slope is preferred, despite penalizing against the extra degree of freedom. There is a strong indication that this inner slope needs to be determined for each cluster individually, i.e. some clusters have central cores and others have steep cusps. The mass-concentration relation of our sample is in reasonable agreement with predictions based on numerical simulations.Comment: 10 pages, 5 figures, accepted by ApJ. Matches accepted versio

The impact of going beyond the Maxwell distribution in direct dark matter detection rates

We consider direct dark matter detection rates and investigate the difference between a standard Maxwell-Boltzmann velocity distribution and a "realistic" distribution like the ones extracted from numerical N-body simulations. Sizable differences are observed when such results are compared to the standard Maxwell-Boltzmann distribution. For a light target both the total rate and the annual modulation are reduced by ~25%. For a heavy target the total rate is virtually unchanged, whereas the annual modulation is modified by up to 50%, depending on the WIMP mass and detector energy threshold. We also consider the effect of a possible velocity anisotropy, and the effect is found to be largest for a light target For the realistic velocity distribution the anisotropy may reduce the annual modulation, in contrast to the Maxwell-Boltzmann case.Comment: 13 pages, 10 figures, accepted by Phys. Rev.

What it takes to measure a fundamental difference between dark matter and baryons: the halo velocity anisotropy

Numerous ongoing experiments aim at detecting WIMP dark matter particles from the galactic halo directly through WIMP-nucleon interactions. Once such a detection is established a confirmation of the galactic origin of the signal is needed. This requires a direction-sensitive detector. We show that such a detector can measure the velocity anisotropy beta of the galactic halo. Cosmological N-body simulations predict the dark matter anisotropy to be nonzero, beta~0.2. Baryonic matter has beta=0 and therefore a detection of a nonzero beta would be strong proof of the fundamental difference between dark and baryonic matter. We estimate the sensitivity for various detector configurations using Monte Carlo methods and we show that the strongest signal is found in the relatively few high recoil energy events. Measuring beta to the precision of ~0.03 will require detecting more than 10^4 WIMP events with nuclear recoil energies greater than 100 keV for a WIMP mass of 100 GeV and a 32S target. This number corresponds to ~10^6 events at all energies. We discuss variations with respect to input parameters and we show that our method is robust to the presence of backgrounds and discuss the possible improved sensitivity for an energy-sensitive detector.Comment: 15 pages, 8 figures, accepted by JCAP. Matches accepted versio

Stirring N-body systems: Universality of end states

We study the evolution of the phase-space of collisionless N-body systems under repeated stirrings or perturbations. We find convergence towards a limited solution group, in accordance with Hansen 2010, that is independent of the initial system and environmental conditions, paying particular attention to the assumed gravitational paradigm (Newtonian and MOND). We examine the effects of changes to the perturbation scheme and in doing so identify a large group of perturbations featuring radial orbit instability (ROI) which always lead to convergence. The attractor is thus found to be a robust and reproducible effect under a variety of circumstances

Death effector domain-containing protein induces vulnerability to cell cycle inhibition in triple-negative breast cancer

Lacking targetable molecular drivers, triple-negative breast cancer (TNBC) is the most clinically challenging subtype of breast cancer. In this study, we reveal that Death Effector Domain-containing DNA-binding protein (DEDD), which is overexpressed in > 60% of TNBCs, drives a mitogen-independent G1/S cell cycle transition through cytoplasm localization. The gain of cytosolic DEDD enhances cyclin D1 expression by interacting with heat shock 71 kDa protein 8 (HSC70). Concurrently, DEDD interacts with Rb family proteins and promotes their proteasome-mediated degradation. DEDD overexpression renders TNBCs vulnerable to cell cycle inhibition. Patients with TNBC have been excluded from CDK 4/6 inhibitor clinical trials due to the perceived high frequency of Rb-loss in TNBCs. Interestingly, our study demonstrated that, irrespective of Rb status, TNBCs with DEDD overexpression exhibit a DEDD-dependent vulnerability to combinatorial treatment with CDK4/6 inhibitor and EGFR inhibitor in vitro and in vivo. Thus, our study provided a rationale for the clinical application of CDK4/6 inhibitor combinatorial regimens for patients with TNBC