5 research outputs found

    Islamic-Catholic Relations: A Local and Global Comparison

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    In our modern world, religion remains one of the most important aspects of an individual’s life, no matter what faith they choose to celebrate. Given the world’s increasing interconnectedness and continuing globalization, members of different faiths are becoming more exposed to communities of one another. In modern times, the disagreements between faiths continue just as they have in the past; however there are more efforts on each side to overcome differences and establish a peaceful coexistence and mutual understanding. Two of the most prominent faiths in today’s world are Catholicism and Islam, which have many differences between them. As Americans, we have witnessed firsthand, religious discrimination and stereotyping against the growing Muslim population in the United States, especially since 9/11. Unfortunately members of each faith continue to stereotype and meet each other with hostility. Through all this ignorance and animosity between Islam and Catholicism, there are members of each faith whose goal is to establish a peaceful coexistence. We wish to shed light upon such positive efforts. This paper, written equally from the perspective of being members of the Providence, R.I. and global community promotes positive dialogue and understanding between Muslims and Catholics at home and abroad

    The positive transcriptional elongation factor (P-TEFb) is required for neural crest specification

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    Regulation of gene expression at the level of transcriptional elongation has been shown to be important in stem cells and tumour cells, but its role in the whole animal is only now being fully explored. Neural crest cells (NCCs) are a multipotent population of cells that migrate during early development from the dorsal neural tube throughout the embryo where they differentiate into a variety of cell types including pigment cells, cranio-facial skeleton and sensory neurons. Specification of NCCs is both spatially and temporally regulated during embryonic development. Here we show that components of the transcriptional elongation regulatory machinery, CDK9 and CYCLINT1 of the P-TEFb complex, are required to regulate neural crest specification. In particular, we show that expression of the proto-oncogene c-Myc and c-Myc responsive genes are affected. Our data suggest that P-TEFb is crucial to drive expression of c-Myc, which acts as a ‘gate-keeper’ for the correct temporal and spatial development of the neural crest
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