Thermal optimization of a 3-D integrated circuit

In a 3-D integrated circuit the heat source distribution has a huge effect on the temperature distribution, so an optimal heat source distribution is needed. This paper gives a numerical approach to its thermal optimization, the result can be used for 3-D integrated circuit optimal design

Thermal management of the through silicon vias in 3-D integrated circuits

The through silicon via technology is a promising and preferred way to realize the reliable interconnection for 3-D integrated circuit integration. However, its size and the property of the filled-materials are two factors affecting the thermal behavior of the integrated circuits. In this paper, we design 3-D integrated circuits with different through silicon via models and analyze the effect of different material-filled through silicon vias, aspect ratio and thermal conductivity of the dielectric on the steady-state temperature profiles. The results presented in this paper are expected to aid in the development of thermal design guidelines for through silicon vias in 3-D integrated circuits

Study on the Road Network Connectivity Reliability of Valley City Based on Complex Network

Based on the research progress in related fields and the distribution characteristics of road networks in valley cities, the complex network model of a city road network is established to study its connectivity reliability. Taking Lanzhou as the example, several parameters of the complex network abstracted from the road network are calculated and the practical meanings of them are described, respectively. On this basis, through computing the global efficiency and the relative size of the largest connecting subgraph under intentional attacks and random attacks, respectively, the curves of the above two parameters varying with the attacking times are drawn. The detailed investigation of connectivity reliability of Lanzhou road network is done by analyzing the curves’ tendency. Finally, we find that the network of a valley city has a poor connection and has a lot of dead ends. Besides, the average length of the roads is very long and the holistic connectivity reliability is at a lower level; these are suitable to the group-type distribution of valley city’s road network, and the connectivity reliability of the road network is stronger under random attacks than that under intentional attacks

MAGNETO - ELECTRIC LOGIC DEVICES USING SEMICONDUCTOR CHANNEL WITH LARGE SPIN - ORBIT COUPLING

Antiferromagnetic magneto - electric spin - orbit read ( AF SOR ) logic devices are presented . The devices include a voltage - controlled magnetoelectric ( ME ) layer that switches polarization in response to an electric field from the applied voltage and a narrow channel conductor of a spin - orbit coupling ( SOC ) material on the ME layer . One or more sources and one or more drains , each optionally formed of ferromagnetic material , are provided on the SOC material

胃转流术在肥胖合并2型糖尿病中临床应用

Objective:To explore the stomach turn flow operation application of sugar in obesity type 2 diseases. Methods:A retrospective analysis of 8 cases of stomach turn flow merger cases of type 2 diabetes treatment of obesity. Results:Postoperative blood glucose in patients with complete response rate was 87.5% in 1 year follow-up, all patients with postoperative blood glucose were significantly improved, only 1 case still need to drug control, the total effective rate was 100%. Conclusion:For the treatment of stomach turn flow with obesity with type 2 diabetes. 目的  探讨胃转流手术在肥胖合并2型糖病中的应用。方法 回顾性分析8例胃转流术治疗肥胖合并2型糖尿病病例。结果 术后1年内随访患者血糖完全缓解率达87.5%，所有患者术后血糖均明显好转，仅1例仍需药物控制，总的有效率为100%。结论  胃转流术治疗肥胖合并2型糖尿病有效。

C/EBP-α, involvement of a novel transcription factor in leptin-induced VCAM-1 production in mouse chondrocytes

AbstractLeptin and vascular cell adhesion molecules-1 (VCAM-1) are two important mediators in obesity-related osteoarthritis, while the molecular mechanism linking leptin to VCAM-1 production is still obscure. Here we show that leptin upregulates VCAM-1 mRNA and protein levels in a time- and dose-dependent manner. Mechanistically, leptin induces VCAM-1 promoter activity by increasing the expression of C/EBP-α and facilitating its binding to a newly identified element in the VCAM-1 gene. Gain or loss of function studies reveal a regulatory role of C/EBP-α on VCAM-1 expression. Finally, elevated plasma leptin level correlates to increased C/EBP-α and VCAM-1 production in chondrocytes from obese mice