1,895 research outputs found
Retinal adaptation to spatial correlations
The classical center-surround retinal ganglion cell receptive field is thought to remove the strong spatial correlations in natural scenes, enabling efficient use of limited bandwidth. While early studies with drifting gratings reported robust surrounds (Enroth-Cugell and Robson, 1966), recent measurements with white noise reveal weak surrounds (Chichilnisky and Kalmar, 2002). This might be evidence for dynamical weakening of the retinal surround in response to decreased spatial correlations, which would be predicted by efficient coding theory. Such adaptation is reported in LGN (Lesica et al., 2007), but whether the retina also adapts to correlations is unknown. 

We tested for adaptation by recording simultaneously from ~40 ganglion cells on a multi-electrode array while presenting white and exponentially correlated checkerboards and strips. Measuring from ~200 cells responding to 90 minutes each of white and correlated stimuli, we were able to extract precise spatiotemporal receptive fields (STRFs). We found that a difference-of-Gaussians was not a good fit and the surround was generally displaced from the center. Thus, to assess surround strength we found the center and surround regions and the total weight on the pixels in each region. The relative surround strength was then defined as the ratio of surround weight to center weight. Surprisingly, we found that the majority of recorded cells have a stronger surround under white noise than under correlated noise (p<.05), contrary to naive expectation from theory. The conclusion was robust to different methods of extracting STRFs and persisted with checkerboard and strip stimuli.

To test, without assuming a model, whether the retina decorrelates stimuli, we also measured the pairwise correlations between spike trains of simultaneously recorded neurons under three conditions: white checkerboard, exponentially correlated noise, and scale-free noise. The typical amount of pairwise correlation increased with extent of input correlation, in line with our STRF measurements
BACCHUS-3D/SP A computer programme for the three-dimensional description of sodium single-phase flow in bundle geometry
Dispersion Relations for Thermally Excited Waves in Plasma Crystals
Thermally excited waves in a Plasma crystal were numerically simulated using
a Box_Tree code. The code is a Barnes_Hut tree code proven effective in
modeling systems composed of large numbers of particles. Interaction between
individual particles was assumed to conform to a Yukawa potential. Particle
charge, mass, density, Debye length and output data intervals are all
adjustable parameters in the code. Employing a Fourier transform on the output
data, dispersion relations for both longitudinal and transverse wave modes were
determined. These were compared with the dispersion relations obtained from
experiment as well as a theory based on a harmonic approximation to the
potential. They were found to agree over a range of 0.9<k<5, where k is the
shielding parameter, defined by the ratio between interparticle distance a and
dust Debye length lD. This is an improvement over experimental data as current
experiments can only verify the theory up to k = 1.5.Comment: 8 pages, Presented at COSPAR '0
Transformation of stimulus correlations by the retina
Redundancies and correlations in the responses of sensory neurons seem to
waste neural resources but can carry cues about structured stimuli and may help
the brain to correct for response errors. To assess how the retina negotiates
this tradeoff, we measured simultaneous responses from populations of ganglion
cells presented with natural and artificial stimuli that varied greatly in
correlation structure. We found that pairwise correlations in the retinal
output remained similar across stimuli with widely different spatio-temporal
correlations including white noise and natural movies. Meanwhile, purely
spatial correlations tended to increase correlations in the retinal response.
Responding to more correlated stimuli, ganglion cells had faster temporal
kernels and tended to have stronger surrounds. These properties of individual
cells, along with gain changes that opposed changes in effective contrast at
the ganglion cell input, largely explained the similarity of pairwise
correlations across stimuli where receptive field measurements were possible.Comment: author list corrected in metadat
Soil Nitrogen Dynamics Following Harvesting and Conversion of Red Alder and Douglas-Fir Stands
Drastic reductions in NO3- leaching have been observed after harvesting of mature red alder (Alnus rubra Bong.) stands. Our objective was to examine whether these reduction were linked to changes in soil N dynamics. Adjacent alder and Douglas fir [Pseudotsuga menziessii (Mirbel.) Franco] stands on young glacial soils (Alderwood; a loamy-skeletal, mixed, mesic, ortstein Aquic Haplorthod) in western Washington were harvested and replanted with either alder or Douglas fir seedlings; reference plots were established in nearby undisturbed stands. Three years after site conversion, when NO3- leaching declined most drastically in the harvested alder plots, net N mineralization and net nitrification in the upper soil were determined seasonally by in situ incubation using the buried-bag technique. There were no significant increases in soil NH4-N during incubation, indicating that nitrification rates closely followed net N mineralization in all plots. In the N-poor soils of the harvested and uncut Douglas fir plots, nitrification was consistently \u3c2 \u3e”g N gâ1 per 30 d. In the N-rich alder reference plot, nitrification was highest in summer (52 ”g N gâ1 per 30 d), lowest in winter (4 ”g N gâ1), and intermediate in spring (20 ”g N gâ1). Seasonal fluctuations in nitrification diminished in the harvested alder plots. Nitrification rates were significantly lower than in the uncut alder plot in summer only (5â9 ”g N gâ1 per 30 d), but this difference was insufficient to account for the lower NO3- leaching rates in the conversion plots. Soils in the harvested plots were drier and experienced greater temperature extremes, but these changes did not correlate well with the variability in N-mineralization rates between uncut and harvested alder plots. Nitrification was positively correlated to soil temperature in the uncut alder plot only. The establishment of red alder seedlings did not appear to have influenced the N dynamics in either N-poor or N-rich soils
Ein Referenzmodell fĂŒr virtuelle Unternehmen
Aus der Einleitung:
'Um auf die Herausforderungen und Chancen, die mit dem PhĂ€nomen Globalisierung sowie mit der Entwicklung moderner Informations- und Kommunikationstechnlogien (IKT) verbunden sind, zu reagieren, verfolgen Unternehmen und Freiberufler eine Reihe unterschiedlicher Handlungsoptionen - Kostensenkung, Entwicklung innovativer Produkte etc. Neben diesen eher klassischen Handlungsalternativen wird u.a. durch die Arbeit von Goldman/Nagel/Preis [GNP96] ein Wechsel des GeschĂ€fts-Paradigmas konstatiert. Die zentralen Konzepte dieses Paradigmas sind der Ăbergang von der Massenproduktion zur agilen Produktion (mass customization), die Konzentration auf Kernkompetenzen sowie Kooperationen in virtuellen Organisationen. Die FĂ€higkeit, sich in rasch verĂ€ndernden, fragmentierten MĂ€rkten erfolgreich zu bewegen, scheint dabei am geeignetsten durch den Versuch erworben zu werden, die Organisation von Unternehmen durch Virtualisierung flexibler zu gestalten. Ergebnis dieser Flexibilisierung sind dynamische Unternehmensnetzwerke, die wir als virtuelle Unternehmen bezeichnen
Integrated Crop Livestock Systems--A Key to Sustainable Intensification in Africa
Mixed crop-livestock systems provide livelihoods for a billion people and produce half the worldâs cereal and around a third of its beef and milk. Market orientation and strong and growing demand for food provide powerful incentives for sustainable intensification of both crop and livestock enterprises in smallholdersâ mixed systems in Africa. Better exploitation of the mutually reinforcing nature of crop and livestock systems can contribute to a positive, inclusive growth trajectory that is both ecologically and economically sustainable. In mixed systems, livestock intensification is often neglected relative to crops, yet livestock can make a positive contribution to raising productivity of the entire farming system. Similarly, intensification of crop production can pay dividends for livestock and enhance natural resources management, especially through increased biomass availability. Intensification and improved efficiency of livestock production means less greenhouse gases per unit of milk and more milk per unit of water. This paper argues that the opportunities and challenges justify greater investment in research for development to identify exactly where and how win-win outcomes can be achieved and what incentives, policies, technologies and other features of the enabling environment are needed to enable sustainable, integrated and productive mixed crop livstock systems
Predicted risks of radiogenic cardiac toxicity in two pediatric patients undergoing photon or proton radiotherapy
Background: Hodgkin disease (HD) and medulloblastoma (MB) are common malignancies found in children and young adults, and radiotherapy is part of the standard treatment. It was reported that these patients who received radiation therapy have an increased risk of cardiovascular late effects. We compared the predicted risk of developing radiogenic cardiac toxicity after photon versus proton radiotherapies for a pediatric patient with HD and a pediatric patient with MB.Methods: In the treatment plans, each patient\u27s heart was contoured in fine detail, including substructures of the pericardium and myocardium. Risk calculations took into account both therapeutic and stray radiation doses. We calculated the relative risk (RR) of cardiac toxicity using a linear risk model and the normal tissue complication probability (NTCP) values using relative seriality and Lyman models. Uncertainty analyses were also performed.Results: The RR values of cardiac toxicity for the HD patient were 7.27 (proton) and 8.37 (photon), respectively; the RR values for the MB patient were 1.28 (proton) and 8.39 (photon), respectively. The predicted NTCP values for the HD patient were 2.17% (proton) and 2.67% (photon) for the myocardium, and were 2.11% (proton) and 1.92% (photon) for the whole heart. The predicted ratios of NTCP values (proton/photon) for the MB patient were much less than unity. Uncertainty analyses revealed that the predicted ratio of risk between proton and photon therapies was sensitive to uncertainties in the NTCP model parameters and the mean radiation weighting factor for neutrons, but was not sensitive to heart structure contours. The qualitative findings of the study were not sensitive to uncertainties in these factors.Conclusions: We conclude that proton and photon radiotherapies confer similar predicted risks of cardiac toxicity for the HD patient in this study, and that proton therapy reduced the predicted risk for the MB patient in this study. © 2013 Zhang et al.; licensee BioMed Central Ltd
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