755 research outputs found
Obtaining the structure factors for an epitaxial film using Cu X-ray radiation
Determining atomic positions in thin films by X-ray diffraction is, at present, a task reserved for synchrotron facilities. Here an experimental method is presented which enables the determination of the structure factor amplitudes of thin films using laboratory-based equipment (Cu K[alpha] radiation). This method was tested using an epitaxial 130 nm film of CuMnAs grown on top of a GaAs substrate, which unlike the orthorhombic bulk phase forms a crystal structure with tetragonal symmetry. From the set of structure factor moduli obtained by applying this method, the solution and refinement of the crystal structure of the film has been possible. The results are supported by consistent high-resolution scanning transmission electron microscopy and stoichiometry analyses
Capsular profiling of the Cronobacter genus and the association of specific Cronobacter sakazakii and C. malonaticus capsule types with neonatal meningitis and necrotizing enterocolitis
Background: Cronobacter sakazakii and C. malonaticus can cause serious diseases especially in infants where they are associated with rare but fatal neonatal infections such as meningitis and necrotising enterocolitis.
Methods: This study used 104 whole genome sequenced strains, covering all seven species in the genus, to analyse capsule associated clusters of genes involved in the biosynthesis of the O-antigen, colanic acid, bacterial cellulose, enterobacterial common antigen (ECA), and a previously uncharacterised K-antigen.
Results: Phylogeny of the gnd and galF genes flanking the O-antigen region enabled the defining of 38 subgroups which are potential serotypes. Two variants of the colanic acid synthesis gene cluster (CA1 and CA2) were found which differed with the absence of galE in CA2. Cellulose (bcs genes) were present in all species, but were absent in C. sakazakii sequence type (ST) 13 and clonal complex (CC) 100 strains. The ECA locus was found in all strains. The K-antigen capsular polysaccharide Region 1 (kpsEDCS) and Region 3 (kpsMT) genes were found in all Cronobacter strains. The highly variable Region 2 genes were assigned to 2 homology groups (K1 and K2). C. sakazakii and C. malonaticus isolates with capsular type [K2:CA2:Cell+] were associated with neonatal meningitis and necrotizing enterocolitis. Other capsular types were less associated with clinical infections. Conclusion: This study proposes a new capsular typing scheme which identifies a possible important virulence trait associated with severe neonatal infections. The various capsular polysaccharide structures warrant further investigation as they could be relevant to macrophage survival, desiccation resistance, environmental survival, and biofilm formation in the hospital environment, including neonatal enteral feeding tubes
An asymptotic form of the reciprocity theorem with applications in x-ray scattering
The emission of electromagnetic waves from a source within or near a
non-trivial medium (with or without boundaries, crystalline or amorphous, with
inhomogeneities, absorption and so on) is sometimes studied using the
reciprocity principle. This is a variation of the method of Green's functions.
If one is only interested in the asymptotic radiation fields the generality of
these methods may actually be a shortcoming: obtaining expressions valid for
the uninteresting near fields is not just a wasted effort but may be
prohibitively difficult. In this work we obtain a modified form the reciprocity
principle which gives the asymptotic radiation field directly. The method may
be used to obtain the radiation from a prescribed source, and also to study
scattering problems. To illustrate the power of the method we study a few
pedagogical examples and then, as a more challenging application we tackle two
related problems. We calculate the specular reflection of x rays by a rough
surface and by a smoothly graded surface taking polarization effects into
account. In conventional treatments of reflection x rays are treated as scalar
waves, polarization effects are neglected. This is a good approximation at
grazing incidence but becomes increasingly questionable for soft x rays and UV
at higher incidence angles.
PACs: 61.10.Dp, 61.10.Kw, 03.50.DeComment: 19 pages, 4 figure
Probing New Physics Models of Neutrinoless Double Beta Decay with SuperNEMO
The possibility to probe new physics scenarios of light Majorana neutrino
exchange and right-handed currents at the planned next generation neutrinoless
double beta decay experiment SuperNEMO is discussed. Its ability to study
different isotopes and track the outgoing electrons provides the means to
discriminate different underlying mechanisms for the neutrinoless double beta
decay by measuring the decay half-life and the electron angular and energy
distributions.Comment: 17 pages, 14 figures, to be published in E.P.J.
Single hadron response measurement and calorimeter jet energy scale uncertainty with the ATLAS detector at the LHC
The uncertainty on the calorimeter energy response to jets of particles is
derived for the ATLAS experiment at the Large Hadron Collider (LHC). First, the
calorimeter response to single isolated charged hadrons is measured and
compared to the Monte Carlo simulation using proton-proton collisions at
centre-of-mass energies of sqrt(s) = 900 GeV and 7 TeV collected during 2009
and 2010. Then, using the decay of K_s and Lambda particles, the calorimeter
response to specific types of particles (positively and negatively charged
pions, protons, and anti-protons) is measured and compared to the Monte Carlo
predictions. Finally, the jet energy scale uncertainty is determined by
propagating the response uncertainty for single charged and neutral particles
to jets. The response uncertainty is 2-5% for central isolated hadrons and 1-3%
for the final calorimeter jet energy scale.Comment: 24 pages plus author list (36 pages total), 23 figures, 1 table,
submitted to European Physical Journal
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