A zero G fluid drop injector for the drop dynamics module spacelab experiment

A fluid drop injector was developed to form and release fluid drops into free drift within an experimental apparatus known as the Drop Dynamics Module which is to be flown on an earth orbiting Spacelab. To verify the design concept, a breadboard injector was flown on the NASA KC-135 zero g airplane after which more extensive laboratory 1 g tests were performed to improve the injector design and enable it to meet the module's functional requirements. The breadboard fluid drop injector will be modified and upgraded to flight hardware

Latent entrepreneurship across nations

The paper studies latent entrepreneurship across nations. There are three main findings. First, large numbers of people in the industrial countries say they would prefer to be self-employed. Top of the international ranking of entrepreneurial spirit come Poland (with 80% saying so), Portugal and the USA; bottom of the table come Norway (with 27% saying so), Denmark and Russia. Second, for individuals the probability of preferring to be self-employed is strongly decreasing with age, while the probability of being self-employed is strongly increasing with age. Third, we show that self-employed individuals have noticeably higher job satisfaction than the employed, so people's expressed wish to run their business cannot easily be written off as mistaken. We speculate on why so much entrepreneurial spirit lies dormant

Latent entrepreneurship across nations

The paper studies latent entrepreneurship across nations. There are three main findings. First, large numbers of people in the industrial countries say they would prefer to be self-employed. Top of the international ranking of entrepreneurial spirit come Poland (with 80% saying so), Portugal and the USA; bottom of the table come Norway (with 27% saying so), Denmark and Russia. Second, for individuals the probability of preferring to be self-employed is strongly decreasing with age, while the probability of being self-employed is strongly increasing with age. Third, we show that self-employed individuals have noticeably higher job satisfaction than the employed, so people's expressed wish to run their business cannot easily be written off as mistaken. We speculate on why so much entrepreneurial spirit lies dormant

On Unique Ergodicity in Nonlinear Stochastic Partial Differential Equations

© 2016 Springer Science+Business Media New YorkWe illustrate how the notion of asymptotic coupling provides a flexible and intuitive framework for proving the uniqueness of invariant measures for a variety of stochastic partial differential equations whose deterministic counterpart possesses a finite number of determining modes. Examples exhibiting parabolic and hyperbolic structure are studied in detail. In the later situation we also present a simple framework for establishing the existence of invariant measures when the usual approach relying on the Krylov–Bogolyubov procedure and compactness fails

How the U.S. Air Force Space Command Optimizes Long-Term Investment in Space Systems

Interfaces, 33, p.p. 1-14.United States Air Force Space Command spends billions of dollars each year acquiring and developing launch vehicles and space systems. The space systems in orbit must continually meet defensive and offensive requirements and remain interoperable over time. Space command can launch additional space systems only if it has a launch vehicle of sufficient capacity. Space planners using space and missile optimization analysis (SAMOA) consider a 24-year time horizon when determining which space assets and launch vehicles to fund and procure. A key tool which in SAMOA is an integer linear program called the space command optimizer of utility toolkit (SCOUT) that Space Command uses for long-range planning. SCOUT gives planner insight into the annual funding profiles needed to meet Space Command's acquisition goals. The 1999 portfolio of 74 systems will cost about #310 billion and includes systems that can lift satellites into orbit; yield information on space, surface, and subsurface events, activities, and threats; and destroy terrestrial, airborne, and space targets

Structured matrices, continued fractions, and root localization of polynomials

We give a detailed account of various connections between several classes of objects: Hankel, Hurwitz, Toeplitz, Vandermonde and other structured matrices, Stietjes and Jacobi-type continued fractions, Cauchy indices, moment problems, total positivity, and root localization of univariate polynomials. Along with a survey of many classical facts, we provide a number of new results.Comment: 79 pages; new material added to the Introductio

The viscosity of shoshonitic melts (Vulcanello Peninsula, Aeolian Islands, Italy): insight on the magma ascent in dikes

The viscosity of shoshonitic melts from Vulcanello Peninsula (Vulcano Island, Italy) is experimentally determined at temperatures between 733 K and 1673 K. The water content of the melts varies from 0.03 to 4.75 wt% H2O. The micropenetration technique is employed at ambient pressure in the high viscosity range (109-1012 Pa·s). Falling sphere(s) experiments are performed at 500 and 2000 MPa in the low viscosity range (100.5-103 Pa·s). Results show a decrease of about 2 orders of magnitude in viscosity if ~ 3 wt% of water is added to the dry melt at 1300 K. At high temperature the viscosity of Vulcanello melts is intermediate between that of andesitic and basaltic melts. In contrast, at low temperatures (≤1050 K), the shoshonitic melt is characterized by a lower viscosity with respect to the two previous melts. Based on our new data set, a calculation model is proposed to predict the viscosity of the shoshonitic melts as a function of temperature and water content. The viscosity data are used to constrain the ascent velocity of shoshonitic magmas from Vulcanello within dikes. Using petrological data (temperature and crystal content of the magma) and volcanological information (geometrical parameters of the eruptive fissure and depth of magma storage), we estimate the time scale for the ascent of magma from the main reservoir to the surface. Results show time scales in the order of hours to few days. We conclude that the rapid ascent of poorly evolved melts from Moho depths should be taken into account for the hazard assessment of Vulcano Island

Raman Spectroscopy of Carbon Materials

Use of carbon materials is no longer limited to diamond jewelry or graphite pencils and lubricants. The last decade has witnessed an explosion of technological applications driven by the development of fabrication methods and the discovery of several new classes of pure carbon. Structural diversity exhibited by the carbon atoms, from local chemical order to long-range crystalline order, is key to understanding their physical and chemical properties and in future materials development. This article summarizes the use of Raman spectroscopy as a principal tool to investigate the vibrational dynamics of carbon materials and to provide indirect structural characterization of their short-, medium- and long-range order

Heparanase overexpression reduces hepcidin expression, affects iron homeostasis and alters the response to inflammation

Hepcidin is the key regulator of systemic iron availability that acts by controlling the degradation of the iron exporter ferroportin. It is expressed mainly in the liver and regulated by iron, inflammation, erythropoiesis and hypoxia. The various agents that control its expression act mainly via the BMP6/SMAD signaling pathway. Among them are exogenous heparins, which are strong hepcidin repressors with a mechanism of action not fully understood but that may involve the competition with the structurally similar endogenous Heparan Sulfates (HS). To verify this hypothesis, we analyzed how the overexpression of heparanase, the HS degrading enzyme, modified hepcidin expression and iron homeostasis in hepatic cell lines and in transgenic mice. The results showed that transient and stable overexpression of heparanase in HepG2 cells caused a reduction of hepcidin expression and of SMAD5 phosphorylation. Interestingly, the clones showed also altered level of TfR1 and ferritin, indices of a modified iron homeostasis. The heparanase transgenic mice showed a low level of liver hepcidin, an increase of serum and liver iron with a decrease in spleen iron content. The hepcidin expression remained surprisingly low even after treatment with the inflammatory LPS. The finding that modification of HS structure mediated by heparanase overexpression affects hepcidin expression and iron homeostasis supports the hypothesis that HS participate in the mechanisms controlling hepcidin expression