Campus Sexual Violence in the Time of COVID-l9

Campus sexual assault (CSA) was likely on the rise in the United States (Koss et al., 2022) even prior to the COVID-19 pandemic, during which there was a global increase in violence against women. The present study is a needed addition to the limited rigorous scientific studies on the impact of the COVID-19 pandemic on campus sexual assault (CSA). A mixed-methods, ecological, and critical feminist approach was used to investigate CSA during the mitigation period. The present study specifically utilized the Sexual Experiences Survey (Koss et al., 2007) to assess changes in frequency of victimization within two representative samples of the Bucknell University student body between winter 2018 and fall 2022, and semi-structured interviews with 18 former or current Bucknell University undergraduate students were used to gather exploratory qualitative data on student experiences of interpersonal violence (IPV) and/or recovery in fall 2020 and spring 2021. Quantitative analyses using chi-square tests of independence suggest that rates of sexual violence were not significantly different between the two samples even after controlling for class year, gender and/or Greek Life affiliation status. Themes of victimization attributed in some way to COVID-19, barriers to microsystem and exosystem level resources, and fraternity men’s disproportionate access to unsurveilled spaces emerged using a Grounded Theory, Ecological Systems Theory, and critical feminist approaches to qualitative analysis. Results suggest that anti-IPV education should be considered a critical element of University pandemic response in the future, and that pandemic mitigations may have exacerbated the effects of an already unequal power structure. Future research should investigate the experiences of students 2 who were first-years during fall of 2020, and the experiences of students of color, particularly Black, Latine, Indigenous, and Asian undergraduate women’s experiences of sexual violence during this period

Follow-Up: Provision of Buprenorphine to Pregnant Women by For-Profit Clinics in an Appalachian City

Objective: This study was completed as a follow up to research regarding buprenorphine Medication Assisted Therapy (MAT) in Johnson City Tennessee for-profit clinics. We wished to determine the practice patterns over the last three years. Methods: Johnson City for-profit Medical Assisted Therapy clinics were called with a telephone survey. When the clinic representative answered the phone, they were asked questions regarding patient costs for therapy, insurance coverage, counseling offered on site, and opportunities for tapering while 20 weeks pregnant. Results: At all the MAT clinics contacted, the representative informed us that tapering in pregnancy could be considered contrary to current national guidelines. 43% of the clinics are now accepting insurance as compared to 0% in the 2016 study. The average weekly cost per visit remained consistent. Conclusion: The concept of tapering buprenorphine during pregnancy appears to have become a standard of care for this community and it is offered at all of the clinics that were contacted, some even require it, even though national organizations such as American College of Obstetricians and Gynecologists and American Society of Addiction Medicine; do not recommend this approach. Patients who have insurance including government funded insurance, are now able to obtain buprenorphine with no out of pocket expense at numerous clinics. The high cost for the uninsured patient continues to create an environment conducive to buprenorphine diversion

Concurrent Gaming Disorder/Internet Gaming Disorder and Electronic Nicotine Delivery Systems Dependency in Emerging Adults [pre-print]

A growing proportion of young adults report regularly playing video games and using electronic nicotine delivery systems (ENDS). Although video gaming is often normative and adaptive, excessive gaming is associated with adverse health outcomes and dependency, as seen in gaming disorder/internet gaming disorder (GD/IGD). Possible additive detrimental effects of ENDS use on the physical outcomes of GD/IGD lend particular concern to these concurrent behaviors. The present study explored group differences in concurrent ENDS and GD/IGD dependency by demographic factors, including age, sex, gender, sexual orientation, racial identity, relationship status, and year in school. The interaction effect of symptoms of attention-deficit hyperactivity disorder (ADHD) on the association between ENDS dependency and GD/IGD was also examined. Lastly, group differences in ADHD symptoms for individuals who endorse (1) neither GD/IGD nor ENDS dependency, (2) either GD/IGD or ENDS dependency, or (3) both GD/IGD and ENDS dependency were explored. Data were collected in a large, multi-university sample of college students (N = 1,054). Higher symptoms of GD/IGD were positively associated with greater symptoms of ENDS dependency. Men and individuals with significant symptoms of ADHD were at an increased risk of concurrent GD/IGD and ENDS dependency. These results may be used to identify demographic and psychological associations linked to these comorbidities, ultimately informing future prevention strategies

BPEX Pig Health Scheme: a useful monitoring system for respiratory disease control in pig farms?

<p>Abstract</p> <p>Background</p> <p>Respiratory diseases account for significant economic losses to the UK pig industry. Lesions indicative of respiratory disease in pig lungs at slaughter e.g. pneumonia and pleuritis are frequently recorded to assess herd health or provide data for epidemiological studies. The BPEX Pig Health Scheme (BPHS) is a monitoring system, which informs producers of gross lesions in their pigs' carcasses at slaughter, enabling farm-level decisions to be made. The aim of the study was to assess whether information provided by the BPHS regarding respiratory lesions was associated with respiratory pathogens in the farm, farm management practices and each other.</p> <p>Results</p> <p>BPHS reports were obtained from a subset of 70 pig farms involved in a cross-sectional study conducted in 2008-09 investigating the epidemiology of post-weaning multi-systemic wasting syndrome. The reports were combined with data regarding the presence/absence of several pathogens in the herd and potential farm-level risk factors for respiratory disease. Principal component analysis (PCA) performed on BPHS reports generated three principal components, explaining 71% of the total variance. Enzootic pneumonia score, severe pleurisy and acute pleuropneumonia had the highest loadings for the principal component which explained the largest percentage of the total variance (35%) (BPHS component 1), it was thought that this component identifies farms with acute disease. Using the factor loadings a score for each farm for BPHS component 1 was obtained. As farms' score for BPHS component 1 increased, average carcass weight at slaughter decreased. In addition, farms positive for H1N2 and porcine reproductive and respiratory disease virus (PRRSV) were more likely to have higher levels of severe and mild pleurisy reported by the BPHS, respectively.</p> <p>Conclusions</p> <p>The study found statistical associations between levels of pleurisy recorded by BPHS at slaughter and the presence H1N2 and PRRSV in the herd. There is also some evidence that farms which submit pigs with these lesions may have reduced productivity. However, more research is needed to fully validate the scheme.</p

Exploring why animal health practices are (not) adopted among smallholders in low and middle-income countries: a realist framework and scoping review protocol

BackgroundImproving livestock health is considered critical to address poverty, malnutrition and food insecurity in low- and middle-income countries (LMICs). Modifications of livestock management practices is also increasingly recognized as an important strategy to mitigate global threats such as climate change and novel disease emergence. Smallholders are, however, under various constraints which prohibit them from altering health practices for livestock and little is known about how the adoption of these practices may be promoted. The proposed scoping review aims to systematically map evidence around “what practices are (not) adopted by smallholders under what circumstances, how and why?.”Method and analysisWe conducted initial scoping searches to broadly define types of animal health practices relevant for smallholders in LMICs and formulated search terms. A scoping review protocol was designed and registered. A systematic literature search will be conducted using electronic databases including CAB Abstract, Scopus, MEDLINE, EMBASE, and Web of Science Core Collection. Gray literature will be searched from AGRIS and Standards for Supporting Agricultural Livelihoods in Emergencies. Articles in English, pertaining to the animal health practices considered highly relevant will be considered eligible for inclusion. Articles will be screened at two stages by two independent reviewers; screening of titles, abstracts, and keywords, followed by full-article screening. The first reviewer will review 100% of the articles at both stages. The second reviewer will review a random sample of 20% of the articles at both stages. Any disagreements will be resolved using inputs from the third reviewer. A thematic analysis will be conducted to catalog contexts and mechanisms for adoption and discussed under a realist framework.DiscussionUnderstanding of the mechanisms underlying the adoption of animal health practices by livestock smallholders in LMICs is crucial for successful implementation of interventions including those which are based on a One Health approach. This review will identify the extent of this knowledge across disciplines and inform future research priorities for the design of effective and feasible interventions which can contribute toward Sustainable Development Goal 2.RegistrationThis protocol is registered within the Open Science Framework (https://doi.org/10.17605/OSF.IO/FUQAX)

The spectral difference between solar flare HXR coronal and footpoint sources due to wave-particle interactions

Investigate the spatial and spectral evolution of hard X-ray (HXR) emission from flare accelerated electron beams subject to collisional transport and wave-particle interactions in the solar atmosphere. We numerically follow the propagation of a power-law of accelerated electrons in 1D space and time with the response of the background plasma in the form of Langmuir waves using the quasilinear approximation.}{We find that the addition of wave-particle interactions to collisional transport for a transient initially injected electron beam flattens the spectrum of the footpoint source. The coronal source is unchanged and so the difference in the spectral indices between the coronal and footpoint sources is \Delta \gamma > 2, which is larger than expected from purely collisional transport. A steady-state beam shows little difference between the two cases, as has been previously found, as a transiently injected electron beam is required to produce significant wave growth, especially at higher velocities. With this transiently injected beam the wave-particle interactions dominate in the corona whereas the collisional losses dominate in the chromosphere. The shape of the spectrum is different with increasing electron beam density in the wave-particle interaction case whereas with purely collisional transport only the normalisation is changed. We also find that the starting height of the source electron beam above the photosphere affects the spectral index of the footpoint when Langmuir wave growth is included. This may account for the differing spectral indices found between double footpoints if asymmetrical injection has occurred in the flaring loop.Comment: 10 pages, 10 FIgures, accepted for publication in A&

Book Reviews

Marital Property in Conflict of Laws By Harold Marsh, Jr. Seattle: University of Washington Press, 1952. Pp. reviewer: Harold Wright Holt =============================== Life Insurance and Estate Tax Planning By William J. Bowe Nashville: Vanderbilt University Press, November 1952 Revision. Pp. 109.$2.10 reviewer: Harold G. Wren ================================ Caruthers\u27 History of a Lawsuit Seventh Edition by Sam Gilreath Cincinnati: The W. H. Anderson Company, 1951. Pp. 1088.$17.50. reviewer: Walter Chandler =============================== Legal Status of the Tenant Farmer in the Southeast By Charles S.Mangum Chapel Hill: University of North Carolina Press, 1952.Pp. viii, 478, $7.50. reviewer: Harold W. Hanna

Lamin A/C dysregulation contributes to cardiac pathology in a mouse model of severe spinal muscular atrophy

Cardiac pathology is emerging as a prominent systemic feature of spinal muscular atrophy (SMA), but little is known about the underlying molecular pathways. Using quantitative proteomics analysis, we demonstrate widespread molecular defects in heart tissue from the Taiwanese mouse model of severe SMA. We identify increased levels of lamin A/C as a robust molecular phenotype in the heart of SMA mice and show that lamin A/C dysregulation is also apparent in SMA patient fibroblast cells and other tissues from SMA mice. Lamin A/C expression was regulated in vitro by knockdown of the E1 ubiquitination factor ubiquitin-like modifier activating enzyme 1, a key downstream mediator of SMN-dependent disease pathways, converging on β-catenin signaling. Increased levels of lamin A are known to increase the rigidity of nuclei, inevitably disrupting contractile activity in cardiomyocytes. The increased lamin A/C levels in the hearts of SMA mice therefore provide a likely mechanism explaining morphological and functional cardiac defects, leading to blood pooling. Therapeutic strategies directed at lamin A/C may therefore offer a new approach to target cardiac pathology in SMA

Endemicity of Zoonotic Diseases in Pigs and Humans in Lowland and Upland Lao PDR: Identification of Socio-cultural Risk Factors

In Lao People's Democratic Republic pigs are kept in close contact with families. Human risk of infection with pig zoonoses arises from direct contact and consumption of unsafe pig products. This cross-sectional study was conducted in Luang Prabang (north) and Savannakhet (central-south) Provinces. A total of 59 villages, 895 humans and 647 pigs were sampled and serologically tested for zoonotic pathogens including: hepatitis E virus (HEV), Japanese encephalitis virus (JEV) and Trichinella spiralis; In addition, human sera were tested for Taenia spp. and cysticercosis. Seroprevalence of zoonotic pathogens in humans was high for HEV (Luang Prabang: 48.6%, Savannakhet: 77.7%) and T. spiralis (Luang Prabang: 59.0%, Savannakhet: 40.5%), and lower for JEV (around 5%), Taenia spp. (around 3%) and cysticercosis (Luang Prabang: 6.1, Savannakhet 1.5%). Multiple correspondence analysis and hierarchical clustering of principal components was performed on descriptive data of human hygiene practices, contact with pigs and consumption of pork products. Three clusters were identified: Cluster 1 had low pig contact and good hygiene practices, but had higher risk of T. spiralis. Most people in cluster 2 were involved in pig slaughter (83.7%), handled raw meat or offal (99.4%) and consumed raw pigs' blood (76.4%). Compared to cluster 1, cluster 2 had increased odds of testing seropositive for HEV and JEV. Cluster 3 had the lowest sanitation access and had the highest risk of HEV, cysticercosis and Taenia spp. Farmers which kept their pigs tethered (as opposed to penned) and disposed of manure in water sources had 0.85 (95% CI: 0.18 to 0.91) and 2.39 (95% CI: 1.07 to 5.34) times the odds of having pigs test seropositive for HEV, respectively. The results have been used to identify entry-points for intervention and management strategies to reduce disease exposure in humans and pigs, informing control activities in a cysticercosis hyper-endemic village