17,521 research outputs found
Jamming transitions in a schematic model of suspension rheology
We study the steady-state response to applied stress in a simple scalar model
of sheared colloids. Our model is based on a schematic (F2) model of the glass
transition, with a memory term that depends on both stress and shear rate. For
suitable parameters, we find transitions from a fluid to a nonergodic, jammed
state, showing zero flow rate in an interval of applied stress. Although the
jammed state is a glass, we predict that jamming transitions have an analytical
structure distinct from that of the conventional mode coupling glass
transition. The static jamming transition we discuss is also distinct from
hydrodynamic shear thickening.Comment: 7 pages; 3 figures; improved version with added references. Accepted
for publication in Europhysics Letter
Quantum signatures of chaos in the dynamics of a trapped ion
We show how a nonlinear chaotic system, the parametrically kicked nonlinear
oscillator, may be realised in the dynamics of a trapped, laser-cooled ion,
interacting with a sequence of standing wave pulses. Unlike the original
optical scheme [G.J.Milburn and C.A.Holmes, Phys. Rev A, 44, p4704, (1991)],
the trapped ion enables strongly quantum dynamics with minimal dissipation.
This should permit an experimental test of one of the quantum signatures of
chaos; irregular collapse and revival dynamics of the average vibrational
energy.Comment: 9 pages, 9 Postscript figures, Revtex, submitted to Phys. Rev.
Dilatancy, Jamming, and the Physics of Granulation
Granulation is a process whereby a dense colloidal suspension is converted
into pasty granules (surrounded by air) by application of shear. Central to the
stability of the granules is the capillary force arising from the interfacial
tension between solvent and air. This force appears capable of maintaining a
solvent granule in a jammed solid state, under conditions where the same amount
of solvent and colloid could also exist as a flowable droplet. We argue that in
the early stages of granulation the physics of dilatancy, which requires that a
powder expand on shearing, is converted by capillary forces into the physics of
arrest. Using a schematic model of colloidal arrest under stress, we speculate
upon various jamming and granulation scenarios. Some preliminary experimental
results on aspects of granulation in hard-sphere colloidal suspensions are also
reported.Comment: Original article intended for J Phys Cond Mat special issue on
Granular Materials (M Nicodemi, Ed.
Properties of planetary fluids at high pressure and temperature
In order to derive models of the interiors of Uranus, Neptune, Jupiter and Saturn, researchers studied equations of state and electrical conductivities of molecules at high dynamic pressures and temperatures. Results are given for shock temperature measurements of N2 and CH4. Temperature data allowed demonstration of shock induced cooling in the the transition region and the existence of crossing isotherms in P-V space
Clinician and Patient-reported Outcomes Are Associated With Psychological Factors in Patients With Chronic Shoulder Pain.
Validated clinician outcome scores are considered less associated with psychosocial factors than patient-reported outcome measurements (PROMs). This belief may lead to misconceptions if both instruments are related to similar factors.
We asked: In patients with chronic shoulder pain, what biopsychosocial factors are associated (1) with PROMs, and (2) with clinician-rated outcome measurements?
All new patients between the ages of 18 and 65 with chronic shoulder pain from a unilateral shoulder injury admitted to a Swiss rehabilitation teaching hospital between May 2012 and January 2015 were screened for potential contributing biopsychosocial factors. During the study period, 314 patients were screened, and after applying prespecified criteria, 158 patients were evaluated. The median symptom duration was 9 months (interquartile range, 5.5-15 months), and 72% of the patients (114 patients) had rotator cuff tears, most of which were work injuries (59%, 93 patients) and were followed for a mean of 31.6 days (SD, 7.5 days). Exclusion criteria were concomitant injuries in another location, major or minor upper limb neuropathy, and inability to understand the validated available versions of PROMs. The PROMs were the DASH, the Brief Pain Inventory, and the Patient Global Impression of Change, before and after treatment (physiotherapy, cognitive therapy and vocational training). The Constant-Murley score was used as a clinician-rated outcome measurement. Statistical models were used to estimate associations between biopsychosocial factors and outcomes.
Greater disability on the DASH was associated with psychological factors (Hospital Anxiety and Depression Scale, Pain Catastrophizing Scale combined coefficient, 0.64; 95% CI, 0.25-1.03; p = 0.002) and social factors (language, professional qualification combined coefficient, -6.15; 95% CI, -11.09 to -1.22; p = 0.015). Greater pain on the Brief Pain Inventory was associated with psychological factors (Hospital Anxiety and Depression Scale, Pain Catastrophizing Scale combined coefficient, 0.076; 95% CI, 0.021-0.13; p = 0.006). Poorer impression of change was associated with psychological factors (Hospital Anxiety and Depression Scale, Pain Catastrophizing Scale, Tampa Scale of Kinesiophobia coefficient, 0.93; 95% CI, 0.87-0.99; p = 0.026) and social factors (education, language, and professional qualification coefficient, 6.67; 95% CI, 2.77-16.10; p < 0.001). Worse clinician-rated outcome was associated only with psychological factors (Hospital Anxiety and Depression Scale (depression only), Pain Catastrophizing Scale, Tampa Scale of Kinesiophobia combined coefficient, -0.35; 95% CI, -0.58 to -0.12; p = 0.003).
Depressive symptoms and catastrophizing appear to be key factors influencing PROMs and clinician-rated outcomes. This study suggests revisiting the Constant-Murley score.
Level III, prognostic study
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Investigating the cultural and contextual determinants of antimicrobial stewardship programmes across low-, middle- and high-income countries—A qualitative study
Background
Most of the evidence on antimicrobial stewardship programmes (ASP) to help sustain the effectiveness of antimicrobials is generated in high income countries. We report a study investigating implementation of ASP in secondary care across low-, middle- and high-income countries. The objective of this study was to map the key contextual, including cultural, drivers of the development and implementation of ASP across different resource settings.
Materials and methods
Healthcare professionals responsible for implementing ASP in hospitals in England, France, Norway, India, and Burkina Faso were invited to participate in face-to face interviews. Field notes from observations, documentary evidence, and interview transcripts were analysed using grounded theory approach. The key emerging categories were analysed iteratively using constant comparison, initial coding, going back the field for further data collection, and focused coding. Theoretical sampling was applied until the categories were saturated. Cross-validation and triangulation of the findings were achieved through the multiple data sources.
Results
54 participants from 24 hospitals (England 9 participants/4 hospitals; Norway 13 participants/4 hospitals; France 9 participants/7 hospitals; India 13 participants/ 7 hospitals; Burkina Faso 8 participants/2 hospitals) were interviewed. Across Norway, France and England there was consistency in ASP structures. In India and Burkina Faso there were country level heterogeneity in ASP. State support for ASP was perceived as essential in countries where it is lacking (India, Burkina Faso), and where it was present, it was perceived as a barrier (England, France). Professional boundaries are one of the key cultural determinants dictating involvement in initiatives with doctors recognised as leaders in ASP. Nurse and pharmacist involvement was limited to England. The surgical specialty was identified as most difficult to engage with in each country. Despite challenges, one hospital in India provided the best example of interdisciplinary ASP, championed through organisational leadership.
Conclusions
ASP initiatives in this study were restricted by professional boundaries and hierarchies, with lack of engagement with the wider healthcare workforce. There needs to be promotion of interdisciplinary team work including pharmacists and nurses, depending on the available healthcare workforce in different countries, in ASP. The surgical pathway remains a hard to reach, but critical target for ASP globally. There is a need to develop contextually driven ASP targeting the surgical pathway in different resource settings
Immunologic abnormalities of mice bearing the gld mutation suggest a common pathway for murine nonmalignant lymphoproliferative disorders with autoimmunity.
A generalized Derjaguin approximation for electrical-double-layer interactions at arbitrary separations
Quantum Dynamics of Three Coupled Atomic Bose-Einstein Condensates
The simplest model of three coupled Bose-Einstein Condensates (BEC) is
investigated using a group theoretical method. The stationary solutions are
determined using the SU(3) group under the mean field approximation. This
semiclassical analysis using the system symmetries shows a transition in the
dynamics of the system from self trapping to delocalization at a critical value
for the coupling between the condensates. The global dynamics are investigated
by examination of the stable points and our analysis shows the structure of the
stable points depends on the ratio of the condensate coupling to the
particle-particle interaction, undergoes bifurcations as this ratio is varied.
This semiclassical model is compared to a full quantum treatment, which also
displays the dynamical transition. The quantum case has collapse and revival
sequences superposed on the semiclassical dynamics reflecting the underlying
discreteness of the spectrum. Non-zero circular current states are also
demonstrated as one of the higher dimensional effects displayed in this system.Comment: Accepted to PR
Numerical Evolution of axisymmetric vacuum spacetimes: a code based on the Galerkin method
We present the first numerical code based on the Galerkin and Collocation
methods to integrate the field equations of the Bondi problem. The Galerkin
method like all spectral methods provide high accuracy with moderate
computational effort. Several numerical tests were performed to verify the
issues of convergence, stability and accuracy with promising results. This code
opens up several possibilities of applications in more general scenarios for
studying the evolution of spacetimes with gravitational waves.Comment: 11 pages, 6 figures. To appear in Classical and Quantum Gravit
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