163 research outputs found

    DATA-DRIVEN REAL-TIME GEOSTEERING USING SURFACE DRILLING DATA

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    In this thesis I present a method for estimating lithology or deriving formation properties from real-time surface drilling data. This information can then be used to enhance real-time geosteering capabilities. Current approaches for geosteering often rely on data from an MWD sub. Because of the position of the MWD sub relative to the bit, the MWD sub is relating information that is depth- and time-delayed relative to the bit. In this work, I use a data-driven approach that relies on the use of Hidden Markov Models (HMM) and Change Point Detection (CPD) algorithms to relate surface drilling signals to formation properties/lithology. My approach views the surface drilling data as a multichannel time-series signal which is an advantage over prior approaches that have attempted to derive variations in lithology from surface drilling data. I finally test my approach with two field datasets: the first is the Volve Oilfield in offshore Norway, and the second is the Meramec formation in the Oklahoma STACK. In both case studies, I demonstrate that the use of HMM and/or CPD can substantially enhance resolution of lithology changes from surface drilling data alone and can therefore be a promising approach for use in real-time geosteering decisions

    The Atmospheric Impact of the 1991 Mount Pinatubo Eruption

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    The 1991 eruption of Pinatubo produced about 5 cubic kilometers of dacitic magma and may be the second largest volcanic eruption of the century. Eruption columns reached 40 kilometers in altitude and emplaced a giant umbrella cloud in the middle to lower stratosphere that injected about 17 megatons of SO2, slightly more than twice the largest yielded by the 1982 eruption of El Chichon, Mexico. The SO2 formed sulfate aerosols that produced the largest perturbation to the stratospheric aerosol layer since the eruption of Krakatau in 1883. The aerosol cloud spread rapidly around the Earth in about 3 weeks and attained global coverage by about 1 year after the eruption. Peak local midvisible optical depths of up to 0.4 were measured in late 1992, and globally averaged values were about 0.1 to 0.15 for 2 years. The large aerosol cloud caused dramatic decreases in the amount of net radiation reaching the Earth's surface, producing a climate forcing that was two times stronger than the aerosols of El Chichon. Effects on climate were an observed surface cooling in the northern hemisphere of up to 0.5 to 0.6 C, equivalent to a hemispheric-wide reduction in net radiation of 4 watts per square meter and a cooling of perhaps as large as -0.4 C over large parts of the earth in 1992-93. Climate models seem to have predicted the cooling with a reasonable degree of accuracy. The Pinatubo climate forcing was stronger than the opposite warming of either the El Nino event or anthropogenic greenhouse gases in the period 1991-93. As a result of the presence of the aerosol particles, midlatitude ozone concentrations reached their lowest levels on record during 1992-93, the southern hemisphere 'ozone hole' increased in 1992 to an unprecedented size and ozone depletion rates were observed to be faster than ever before recorded. The atmospheric impact of the Pinatubo eruption has been profound, and it has sparked a lively interest in the role that volcanic aerosols play in climate change. This event has shown that a powerful eruption providing a 15 to 20 megaton release of SO2 into the stratosphere can produce sufficient aerosols to offset the present global warming trends and severely impact the ozone budget

    Cultivation and Immortalization of Human B-Cells Producing a Human Monoclonal IgM Antibody Binding to MDA-LDL: Further Evidence for Formation of Atherogenic MDA-LDL Adducts in Humans In Vivo

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    Oxidatively modified low-density lipoprotein (oLDL) is firmly believed to play an important role in the initiation and development of atherosclerosis, and malonic dialdehyde (MDA) is one of the major lipid peroxidation breakdown products involved in this process. In recent decades, antibodies against MDA-LDL have been detected in human and animal sera. In our study, human B-cells from the peripheral blood of a healthy female donor were fused with the SP2/0 mouse myeloma cell line. Antibody-producing hybridomas were detected by MDA-LDL-IgG/IgM enzyme-linked immunosorbent assays (ELISA) and Cu++-oxidized LDL IgG/IgM (oLAb) ELISA. Cells with supernatants emitting positive signals for antibodies were then cloned and after sufficient multiplication frozen and stored under liquid nitrogen. Due to the loss of antibody-producing ability, we established an MDA-LDL-IgM-producing cell line by recloning. This allowed isolation and immortalization of several human B-cells. The human donor had not been immunized with MDA-modified proteins, thus obviously producing MDA-LDL antibodies in vivo. Furthermore, using these antibodies for in vitro experiments, we were able to demonstrate that MDA epitopes are among the epitopes generated during Cu++-LDL oxidation as well. Finally, these antibodies compete in ELISA and cell culture experiments with MDA as a challenging toxin or ligand

    Detection of volcanic ash clouds from Nimbus 7/total ozone mapping spectrometer

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    Measured radiances from the Version 7 reprocessing of the Nimbus 7/total ozone mapping spectrometer (TOMS) 340- and 380-nm channels are used to detect absorbing particulates injected into the atmosphere after the El Chichon eruption on April 4, 1982. It is shown that while the single-channel reflectivity determined from the 380-nm channel is able to detect clouds and haze composed of nonabsorbing aerosols, the spectral contrast between the 340- and 380-nm channels is sensitive to absorbing particulates such as volcanic ash, desert dust, or smoke from biomass burning. In this paper the spectral contrast between these two channels is used to detect the volcanic ash injection into the atmosphere and to track its evolution for several days. The movement of the ash clouds is shown to be consistent with the motions expected from the National Centers for Environmental Prediction (NCEP)-derived balanced wind fields in the troposphere and lower stratosphere. The movement of the volcanic SO2 cloud detected from TOMS data was also in agreement with the NCEP wind at higher altitudes of up to 100–10 mbar. The vertical wind shear in the neighborhood of the eruption site resulted in a clear separation of the ash and SO2 clouds. The location and movement of the ash cloud are consistent with information obtained by the advanced very high resolution radiometer (AVHRR) instrument on board the NOAA 7 satellite and to ground reports of ash fall

    Anticyclonic precession of a plume in a rotating environment

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    Motivated by potential effects of the Earth’s rotation on the Deepwater Horizon oil plume, we conducted laboratory experiments on salt-water point plumes in a homogeneous rotating environment across a wide range of Rossby numbers 0.02 < Ro < 1.3. We report a striking physical instability in the plume dynamics near the source: after approximately one rotation period, the plume tilts laterally and starts to precess anticyclonically. The mean precession frequency ω scales linearly with the rotation rate Ω as ω ≈ 0.4 Ω. We find no evidence of a critical Rossby number above which precession ceases. We infer that a conventionally defined Rossby number is not an appropriate parameter when the plume is maintained over a long time: provided Ω ≠ 0, rotation is always important to the dynamics. This indicates that precession may occur in persistent oceanic or atmospheric plumes even at low latitudes

    Loss of ATF2 Function Leads to Cranial Motoneuron Degeneration during Embryonic Mouse Development

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    The AP-1 family transcription factor ATF2 is essential for development and tissue maintenance in mammals. In particular, ATF2 is highly expressed and activated in the brain and previous studies using mouse knockouts have confirmed its requirement in the cerebellum as well as in vestibular sense organs. Here we present the analysis of the requirement for ATF2 in CNS development in mouse embryos, specifically in the brainstem. We discovered that neuron-specific inactivation of ATF2 leads to significant loss of motoneurons of the hypoglossal, abducens and facial nuclei. While the generation of ATF2 mutant motoneurons appears normal during early development, they undergo caspase-dependent and independent cell death during later embryonic and foetal stages. The loss of these motoneurons correlates with increased levels of stress activated MAP kinases, JNK and p38, as well as aberrant accumulation of phosphorylated neurofilament proteins, NF-H and NF-M, known substrates for these kinases. This, together with other neuropathological phenotypes, including aberrant vacuolisation and lipid accumulation, indicates that deficiency in ATF2 leads to neurodegeneration of subsets of somatic and visceral motoneurons of the brainstem. It also confirms that ATF2 has a critical role in limiting the activities of stress kinases JNK and p38 which are potent inducers of cell death in the CNS
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