169 research outputs found
Social Stability and Extended Social Balance - Quantifying the Role of Inactive Links in Social Networks
Structural balance in social network theory starts from signed networks with
active relationships (friendly or hostile) to establish a hierarchy between
four different types of triadic relationships. The lack of an active link also
provides information about the network. To exploit the information that remains
uncovered by structural balance, we introduce the inactive relationship that
accounts for both neutral and nonexistent ties between two agents. This
addition results in ten types of triads, with the advantage that the network
analysis can be done with complete networks. To each type of triadic
relationship, we assign an energy that is a measure for its average occupation
probability. Finite temperatures account for a persistent form of disorder in
the formation of the triadic relationships. We propose a Hamiltonian with three
interaction terms and a chemical potential (capturing the cost of edge
activation) as an underlying model for the triadic energy levels. Our model is
suitable for empirical analysis of political networks and allows to uncover
generative mechanisms. It is tested on an extended data set for the standings
between two classes of alliances in a massively multi-player on-line game
(MMOG) and on real-world data for the relationships between countries during
the Cold War era. We find emergent properties in the triadic relationships
between the nodes in a political network. For example, we observe a persistent
hierarchy between the ten triadic energy levels across time and networks. In
addition, the analysis reveals consistency in the extracted model parameters
and a universal data collapse of a derived combination of global properties of
the networks. We illustrate that the model has predictive power for the
transition probabilities between the different triadic states.Comment: 21 pages, 10 figure
Thermal bremsstrahlung probing the thermodynamical state of multifragmenting systems
Inclusive and exclusive hard-photon (E 30 MeV) production in five
different heavy-ion reactions (Ar+Au, Ag, Ni,
C at 60{\it A} MeV and Xe+Sn at 50{\it A} MeV) has been
studied coupling the TAPS photon spectrometer with several charged-particle
multidetectors covering more than 80% of 4. The measured spectra, slope
parameters and source velocities as well as their target-dependence, confirm
the existence of thermal bremsstrahlung emission from secondary nucleon-nucleon
collisions that accounts for roughly 20% of the total hard-photon yield. The
thermal slopes are a direct measure of the temperature of the excited nuclear
systems produced during the reaction.Comment: 4 pages, 3 figures, Proceedings CRIS 2000, 3rd Catania Relativistic
Ion Studies, "Phase Transitions in Strong Interactions: Status and
Perspectives", Acicastello, Italy, May 22-26, 2000 (to be published in Nuc.
Phys. A
Hard photon and neutral pion production in cold nuclear matter
The production of hard photons and neutral pions in 190 MeV proton induced
reactions on C, Ca, Ni, and W targets has been for the first time concurrently
studied. Angular distributions and energy spectra up to the kinematical limit
are discussed and the production cross-sections are presented. From the target
mass dependence of the cross-sections the propagation of pions through nuclear
matter is analyzed and the production mechanisms of hard photons and primordial
pions are derived. It is found that the production of subthreshold particles
proceeds mainly through first chance nucleon-nucleon collisions. For the most
energetic particles the mass scaling evidences the effect of multiple
collisions.Comment: submitted to Phys. Lett.
Estimating Informal Caregiving Time from Patient EQ-5D Data: The Informal CARE Effect (iCARE) Tool
Background: Families and friends provide a considerable proportion of care for patients and elderly people. Caregiving can have substantial effects on caregivers’ lives, health, and well-being. However, because clinical trials rarely assess these effects, no information on caregiver burden is available when evaluating the cost effectiveness of treatments. Objective: This study develops an algorithm for estimating caregiver time using information that is typically available in clinical trials: the EQ-5D scores of patients and their gender. Methods: Four datasets with a total of 8012 observations of dyads of caregivers and a gamma model with a log-link estimated with the Bayesian approach were used to estimate the statistical association between patient scores on the EQ-5D-3L dimensions and the numbers of hours of care provided by caregivers during the previous week. The model predicts hours of care as mean point estimates with 95% credible intervals or entire distributions. Results: Model predictions of hours of care based on the five EQ-5D dimensions ranged from 13.06 (12.7–14.5) h/week for female patients reporting no health problems but receiving informal care to 52.82 (39.38–66.26) for male patients with the highest level of problems on all EQ-5D dimensions. Conclusions: The iCARE algorithm developed in this study allows researchers who only have patient-level EQ-5D data to estimate the mean hours of informal care received per week, including a 95% Bayesian credible interval. Caregiver time can be multiplied with a monetary value for caregiving, enabling the inclusion of informal care costs in economic evaluations. We recommend using the tool for samples that fall within the confidence intervals of the characteristics of our samples: men (age range 47.0–104.2 years), women (age range 55–103 years)
Development of Population Tariffs for the CarerQol Instrument for Hungary, Poland and Slovenia
__Background:__ The CarerQol instrument can be used in economic evaluations to measure the care-related quality of life of informal caregivers. Tariff sets are available for Australia, Germany, Sweden, the Netherlands, the UK, and the USA.
__Objective:__ Our objective was to develop tariff sets for the CarerQol instrument for Hungary, Poland and Slovenia and to compare these with the existing value sets.
__Methods:__ Discrete-choice experiments were carried out in Hungary, Poland and Slovenia. Data were collected through an online survey between November 2018 and January 2019, using representative samples of 1000 respondents per country. Tariffs were calculated from coefficient estimates from panel mixed multinomial logit models with random parameters.
__Results:__ All seven CarerQol domains contributed significantly to the utility associated with different caregiving situations. Attributes valued highest were ‘physical health
Evidence for Thermal Equilibration in Multifragmentation Reactions probed with Bremsstrahlung Photons
The production of nuclear bremsstrahlung photons (E 30 MeV) has
been studied in inclusive and exclusive measurements in four heavy-ion
reactions at 60{\it A} MeV. The measured photon spectra, angular distributions
and multiplicities indicate that a significant part of the hard-photons are
emitted in secondary nucleon-nucleon collisions from a thermally equilibrated
system. The observation of the thermal component in multi-fragment
Ar+Au reactions suggests that the breakup of the thermalized
source produced in this system occurs on a rather long time-scale.Comment: Revised version, accepted for publication in Physical Review Letters.
4 pages, 4 fig
Survival or Revival: Long-Term Preservation Induces a Reversible Viable but Non-Culturable State in Methane-Oxidizing Bacteria
Knowledge on long-term preservation of micro-organisms is limited and research in the field is scarce despite its importance for microbial biodiversity and biotechnological innovation. Preservation of fastidious organisms such as methane-oxidizing bacteria (MOB) has proven difficult. Most MOB do not survive lyophilization and only some can be cryopreserved successfully for short periods. A large-scale study was designed for a diverse set of MOB applying fifteen cryopreservation or lyophilization conditions. After three, six and twelve months of preservation, the viability (via live-dead flow cytometry) and culturability (via most-probable number analysis and plating) of the cells were assessed. All strains could be cryopreserved without a significant loss in culturability using 1% trehalose in 10-fold diluted TSB (TT) as preservation medium and 5% DMSO as cryoprotectant. Several other cryopreservation and lyophilization conditions, all of which involved the use of TT medium, also allowed successful preservation but showed a considerable loss in culturability. We demonstrate here that most of these non-culturables survived preservation according to viability assessment indicating that preservation induces a viable but non-culturable (VBNC) state in a significant fraction of cells. Since this state is reversible, these findings have major implications shifting the emphasis from survival to revival of cells in a preservation protocol. We showed that MOB cells could be significantly resuscitated from the VBNC state using the TT preservation medium
Suppression of soft nuclear bremsstrahlung in proton-nucleus collisions
Photon energy spectra up to the kinematic limit have been measured in 190 MeV
proton reactions with light and heavy nuclei to investigate the influence of
the multiple-scattering process on the photon production. Relative to the
predictions of models based on a quasi-free production mechanism a strong
suppression of bremsstrahlung is observed in the low-energy region of the
photon spectrum. We attribute this effect to the interference of photon
amplitudes due to multiple scattering of nucleons in the nuclear medium.Comment: 12 pages, 3 figures, submitted to Phys. Rev. Let
Family coordination in families who have a child with autism spectrum disorder
Little is known about the interactions of families where there is a child with autism spectrum disorder (ASD). The present study applies the Lausanne Trilogue Play (LTP) to explore both its applicability to this population as well as to assess resources and areas of deficit in these families. The sample consisted of 68 families with a child with ASD, and 43 families with a typically developing (TD) child. With respect to the global score for family coordination there were several negative correlations: the more severe the symptoms (based on the child’s ADOS score), the more family coordination was dysfunctional. This correlation was particularly high when parents had to play together with the child. In the parts in which only one of the parents played actively with the child, while the other was simply present, some families did achieve scores in the functional range, despite the child’s symptom severity. The outcomes are discussed in terms of their clinical implications both for assessment and for interventio
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