581 research outputs found
Short Note on the Unemployment Rate of the French Overseas Regions
This article analyzes the hysteresis hypothesis in the unemployment rates of the four French overseas regions (Guadeloupe, Martinique, Guyana, Reunion) [FORs] over the period 1993-2008. We use standard univariate and panel unit root tests, among them Choi (2006) and Lopez (2009) that account for cross-sectional dependence and have improved performance when the number of countries and the time dimension of the data are limited. Our results cannot reject the null hypothesis of a unit root and so find evidence supporting hysteresis in the unemployment rates for the FORs.panel unit root, unemployment, hysteresis.
Parametric oscillator based on non-linear vortex dynamics in low resistance magnetic tunnel junctions
Radiofrequency vortex spin-transfer oscillators based on magnetic tunnel
junctions with very low resistance area product were investigated. A high power
of excitations has been obtained characterized by a power spectral density
containing a very sharp peak at the fundamental frequency and a series of
harmonics. The observed behaviour is ascribed to the combined effect of spin
transfer torque and Oersted-Amp\`ere field generated by the large applied
dc-current. We furthermore show that the synchronization of a vortex
oscillation by applying a ac bias current is mostly efficient when the external
frequency is twice the oscillator fundamental frequency. This result is
interpreted in terms of a parametric oscillator.Comment: 4 pages, 4 figure
Methodological Aspects of Spontaneous Crystalluria Studies in Calcium Stone Formers
Despite nearly a half-century of study, the clinical value of spontaneous crystalluria (Cx) examinations in calcium stone formers (CaSF) is still uncertain. The analytical complexity of urine particle study is largely responsible for this situation. As a result, there is no consensus regarding technical methods in Cx with several techniques for urine sampling and three different instruments currently used for particle study, namely, particle counting (PC), light microscopy (LM) and petrographic microscopy (PM). In this work, we first examined urine sampling and instrument methods regarding their appropriateness for Cx studies. Then we performed a comparative analysis of Cx studies in CaSF. Despite many technical and clinical discrepancies, several studies agree that the frequency of all particles and of the weddellite and whewellite calcium oxalate (CaOx) crystalline phases are increased in CaSF as compared to normal subjects (NS). Particle sizes and aggregation ratio are also often increased. Altogether, these results reinforce the need for an efficient method for Cx studies in these patients. Examining each technique leads us to conclude that most particle parameters can be studied by direct LM observation of freshly voided urine samples, i.e., urine samples without any separation steps. For clinical applications, several examinations should be performed, first to define the specific Cx characteristics in a patient, then for the study of treatment efficiency on Cx control, and finally, during the patient follow-up. Due to Cx variability in each patient, the frequency of Cx examinations during each phase needs to be determined in long-term comparative prospective studies of CaSF
Urinary Calculi: Review of Classification Methods and Correlations with Etiology
Current physical and chemical methods available for urinary stones analysis are critically reviewed. No one method is sufficient to provide all the clinically useful information on the structure and composition of the stones. We show that a combination of refined morphological and structural examination of stone with optical microscopy, complemented by compositional analysis using infrared spectroscopy of the core, cross-section and surface of calculi, provides a precise and reliable method for identifying the structure and crystalline composition, and permits quantification of stone components while being highly cost effective. Using such morphoconstitutional studies leads to a classification of urinary stones in seven distinctive types and twenty-one subtypes among monohydrate (whewellite) and dihydrate (weddellite) calcium oxalates, phosphates, uric acid, urates, protein, and cystine calculi. Furthermore, all of the recognized sub-types exhibit correlations with specific pathophysiologic conditions. We conclude that such morphoconstitutional refined analysis and classification of urinary calculi is of interest to properly identify the type of stone disease and provides clues to etiopathogeny
Pathogenicity of proteinase 3-anti-neutrophil cytoplasmic antibody in granulomatosis with polyangiitis: Implications as biomarker and future therapies
Granulomatosis with polyangiitis (GPA) is a rare but serious necrotizing auto-immune vasculitis. GPA is mostly associated with the presence of Anti-Neutrophil Cytoplasmic Antibody (ANCA) targeting proteinase 3 (PR3-ANCA), a serine protease contained in neutrophil granules but also exposed at the membrane. PR3-ANCAs have a proven fundamental role in GPA: they bind neutrophils allowing their auto-immune activation responsible for vasculitis lesions. PR3-ANCAs bind neutrophil surface on the one hand by their Fab binding PR3 and on the other by their Fc binding Fc gamma receptors. Despite current therapies, GPA is still a serious disease with an important mortality and a high risk of relapse. Furthermore, although PR3-ANCAs are a consistent biomarker for GPA diagnosis, relapse management currently based on their level is inconsistent. Indeed, PR3-ANCA level is not correlated with disease activity in 25% of patients suggesting that not all PR3-ANCAs are pathogenic. Therefore, the development of new biomarkers to evaluate disease activity and predict relapse and new therapies is necessary. Understanding factors influencing PR3-ANCA pathogenicity, i.e. their potential to induce auto-immune activation of neutrophils, offers interesting perspectives in order to improve GPA management. Most relevant factors influencing PR3-ANCA pathogenicity are involved in their interaction with neutrophils: level of PR3 autoantigen at neutrophil surface, epitope of PR3 recognized by PR3-ANCA, isotype and glycosylation of PR3-ANCA. We detailed in this review the advances in understanding these factors influencing PR3-ANCA pathogenicity in order to use them as biomarkers and develop new therapies in GPA as part of a personalized approach
3D URBAN GEOVISUALIZATION: IN SITU AUGMENTED AND MIXED REALITY EXPERIMENTS
In this paper, we assume that augmented reality (AR) and mixed reality (MR) are relevant contexts for 3D urban geovisualization, especially in order to support the design of the urban spaces. We propose to design an in situ MR application, that could be helpful for urban designers, providing tools to interactively remove or replace buildings in situ. This use case requires advances regarding existing geovisualization methods. We highlight the need to adapt and extend existing 3D geovisualization pipelines, in order to adjust the specific requirements for AR/MR applications, in particular for data rendering and interaction. In order to reach this goal, we focus on and implement four elementary in situ and ex situ AR/MR experiments: each type of these AR/MR experiments helps to consider and specify a specific subproblem, i.e. scale modification, pose estimation, matching between scene and urban project realism, and the mix of real and virtual elements through portals, while proposing occlusion handling, rendering and interaction techniques to solve them
Epitaxial rhenium microwave resonators
International audienceWe have fabricated rhenium microwave resonators from epitaxial films. We have used thin films of different structural quality depending on their growth conditions. The resonators were coupled to a microwave transmission line which allows the measurement of their resonance frequencies and internal quality factors. From the resonance frequency at low temperature , the effective penetration depth and the London penetration depth of the rhenium film are extracted
Improving transferability of introduced species' distribution models: new tools to forecast the spread of a highly invasive seaweed
Extent: 13 p.The utility of species distribution models for applications in invasion and global change biology is critically dependent on their transferability between regions or points in time, respectively. We introduce two methods that aim to improve the transferability of presence-only models: density-based occurrence thinning and performance-based predictor selection. We evaluate the effect of these methods along with the impact of the choice of model complexity and geographic background on the transferability of a species distribution model between geographic regions. Our multifactorial experiment focuses on the notorious invasive seaweed Caulerpa cylindracea (previously Caulerpa racemosa var. cylindracea) and uses Maxent, a commonly used presence-only modeling technique. We show that model transferability is markedly improved by appropriate predictor selection, with occurrence thinning, model complexity and background choice having relatively minor effects. The data shows that, if available, occurrence records from the native and invaded regions should be combined as this leads to models with high predictive power while reducing the sensitivity to choices made in the modeling process. The inferred distribution model of Caulerpa cylindracea shows the potential for this species to further spread along the coasts of Western Europe, western Africa and the south coast of Australia.Heroen Verbruggen, Lennert Tyberghein, Gareth S. Belton, Frederic Mineur, Alexander Jueterbock, Galice Hoarau, C. Frederico D. Gurgel, Olivier De Clerc
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