Excitation of Rydberg wave packets with chirped laser pulses

We study Rydberg wave packets produced by pairs of time separated femtosecond laser pulses. The time separation ranges from femtosecond to picosecond time scales. The wave packets consist predominantly of f states of principal quantum numbers n = 22-32 in Li. With a direct analysis of the field ionization spectra the n-level-resolved classical orbit times are displayed. By chirping the second excitation pulse we demonstrate controlled amplitude oscillations of n-level amplitudes on femtosecond time scales.Fil: Preclíková, J.. University of Bergen; NoruegaFil: Kozák, M.. Karlova Univerzita; República ChecaFil: Fregenal, Daniel Eduardo. Comisión Nacional de Energía Atómica. Centro Atómico Bariloche; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte; ArgentinaFil: Frette, Ø.. University of Bergen; NoruegaFil: Hamre, B.. University of Bergen; NoruegaFil: Hjertaker, B. T.. University of Bergen; NoruegaFil: Hansen, J. P.. University of Bergen; NoruegaFil: Kocbach, L.. University of Bergen; Norueg

Demographic, clinical and antibody characteristics of patients with digital ulcers in systemic sclerosis: data from the DUO Registry

OBJECTIVES: The Digital Ulcers Outcome (DUO) Registry was designed to describe the clinical and antibody characteristics, disease course and outcomes of patients with digital ulcers associated with systemic sclerosis (SSc). METHODS: The DUO Registry is a European, prospective, multicentre, observational, registry of SSc patients with ongoing digital ulcer disease, irrespective of treatment regimen. Data collected included demographics, SSc duration, SSc subset, internal organ manifestations, autoantibodies, previous and ongoing interventions and complications related to digital ulcers. RESULTS: Up to 19 November 2010 a total of 2439 patients had enrolled into the registry. Most were classified as either limited cutaneous SSc (lcSSc; 52.2%) or diffuse cutaneous SSc (dcSSc; 36.9%). Digital ulcers developed earlier in patients with dcSSc compared with lcSSc. Almost all patients (95.7%) tested positive for antinuclear antibodies, 45.2% for anti-scleroderma-70 and 43.6% for anticentromere antibodies (ACA). The first digital ulcer in the anti-scleroderma-70-positive patient cohort occurred approximately 5 years earlier than the ACA-positive patient group. CONCLUSIONS: This study provides data from a large cohort of SSc patients with a history of digital ulcers. The early occurrence and high frequency of digital ulcer complications are especially seen in patients with dcSSc and/or anti-scleroderma-70 antibodies