仙台大学スポーツ情報マスメディア学科新入生に対する動向調査分析結果と課題

The Department of Sport Intelligence & Mass Media (hereinafter referred to as "the Dept of SIM") was established at Sendai University in this academic year. This report is an attitude survey of its new students, which was done in May. The research showed as followed; 1 . Most students had higher interest in the activity of the Dept of SIM\u27s educational program. 2 . Most students had interest in the extracurricular activities of the Dept of SIM\u27s educational program. 3 . Most students had clear career plans of their own

Identification of Novel Senescent Markers in Small Extracellular Vesicles

Senescent cells exhibit several typical features, including the senescence-associated secretory phenotype (SASP), promoting the secretion of various inflammatory proteins and small extracellular vesicles (EVs). SASP factors cause chronic inflammation, leading to age-related diseases. Recently, therapeutic strategies targeting senescent cells, known as senolytics, have gained attention; however, noninvasive methods to detect senescent cells in living organisms have not been established. Therefore, the goal of this study was to identify novel senescent markers using small EVs (sEVs). sEVs were isolated from young and senescent fibroblasts using three different methods, including size-exclusion chromatography, affinity column for phosphatidylserine, and immunoprecipitation using antibodies against tetraspanin proteins, followed by mass spectrometry. Principal component analysis revealed that the protein composition of sEVs released from senescent cells was significantly different from that of young cells. Importantly, we identified ATP6V0D1 and RTN4 as novel markers that are frequently upregulated in sEVs from senescent and progeria cells derived from patients with Werner syndrome. Furthermore, these two proteins were significantly enriched in sEVs from the serum of aged mice. This study supports the potential use of senescent markers from sEVs to detect the presence of senescent cells in vivo

仙台大学スポーツ情報マスメディア学科の教育と運営戦略 : 新入生に対してのアプローチ

The Department of Sport Intelligence & Mass Media (hereinafter referred to as "the Dept SIM") was established at Sendai University in this academic year. The purpose of this report is to show the educational ideas, educational contents and the management strategy of this new department. The Dept SIM aims to foster talents who have high-level ability to deal with sport information. Purposes of the Dept SIM management are as following; first is to take information with dignity, second is to continue to mention the essence, third is to establish its laboratory and to cooperate with a variety of other institutions