The Czechoslovak Privatization Auction: An Empirical Investigation

The 1992 Czechoslovak mass-privatization program resembled a multiround Walrasian auction with tatonnement in which participants, endowed with points, bid simultaneously for non-uniform products, i.e., shares. The creation of this artificial primary market provides economists with a unique opportunity to investigate empirically (1) the role and aims of the auctioneer in a politically-motivated giveaway scheme, (2) the price-setting mechanism, and (3) the bidding strategies and rationality of the auction's participants. Unlike more conventional auctions, price discovery was only a secondary motive to the auctioneer. The principal aim was to transfer the shares quickly to the investing public in a politically acceptable manner. We show that the price-updating rules adopted alter each bidding round did achieve the auctioneer's principal aim, but they also served to inject noise. The results suggest an inherent tradeoff between socially acceptable outcomes in such auctions and efficient price discovery

INTRAVENOUS IMMUNOGLOBULIN INDUCES ANERGY STATELIKE OF AUTO-REACTIVE B LYMPHOCYTES IN SJÖGREN’S SYNDROME

Oral Communication presented at the ";Forum des Jeunes Chercheurs";, Brest (France) 2011

Deux méthodes de comparaison d'images pour l'identification d'objets à partir de données prospectives

Cette étude aborde le problème de l'identification d'objets mobiles à partir de données délivrées par un senseur prospectif dont la conception est actuellement en cours. Le but est d'estimer la faisabilité d'une telle identification à l'aide d'outils disponibles à ce jour en reconnaissance des formes. On présente dans ce papier la réalisation complète d'une chaîne de simulation, comprenant à la fois la génération des données (non disponibles) et la mise en place de processus capables de les exploiter dans un but d'identification. Des paramètres variables contrôlent la nature des images (richesse, niveau de bruit) tout au long de la simulation, ceci afin de pouvoir prendre en compte des données de qualité variable

Monitoring global protein thiol-oxidation and protein S-mycothiolation in Mycobacterium smegmatis under hypochlorite stress.

Hillion M, Bernhardt J, Busche T, et al. Monitoring global protein thiol-oxidation and protein S-mycothiolation in Mycobacterium smegmatis under hypochlorite stress. Sci Rep. 2017;7(1): 1195.Mycothiol (MSH) is the major low molecular weight (LMW) thiol in Actinomycetes. Here, we used shotgun proteomics, OxICAT and RNA-seq transcriptomics to analyse protein S-mycothiolation, reversible thiol-oxidations and their impact on gene expression in Mycobacterium smegmatis under hypochlorite stress. In total, 58 S-mycothiolated proteins were identified under NaOCl stress that are involved in energy metabolism, fatty acid and mycolic acid biosynthesis, protein translation, redox regulation and detoxification. Protein S-mycothiolation was accompanied by MSH depletion in the thiol-metabolome. Quantification of the redox state of 1098 Cys residues using OxICAT revealed that 381 Cys residues (33.6%) showed >10% increased oxidations under NaOCl stress, which overlapped with 40 S-mycothiolated Cys-peptides. The absence of MSH resulted in a higher basal oxidation level of 338 Cys residues (41.1%). The RseA and RshA anti-sigma factors and the Zur and NrdR repressors were identified as NaOCl-sensitive proteins and their oxidation resulted in an up-regulation of the SigH, SigE, Zur and NrdR regulons in the RNA-seq transcriptome. In conclusion, we show here that NaOCl stress causes widespread thiol-oxidation including protein S-mycothiolation resulting in induction of antioxidant defense mechanisms in M. smegmatis. Our results further reveal that MSH is important to maintain the reduced state of protein thiols

In-depth characterization of CD24(high)CD38(high) transitional human B cells reveals different regulatory profiles

International audienc

Superluminal X-shaped beams propagating without distortion along a coaxial guide

In a previous paper [Phys. Rev. E64 (2001) 066603; e-print physics/0001039], we showed that localized Superluminal solutions to the Maxwell equations exist, which propagate down (non-evanescence) regions of a metallic cylindrical waveguide. In this paper we construct analogous non-dispersive waves propagating along coaxial cables. Such new solutions, in general, consist in trains of (undistorted) Superluminal "X-shaped" pulses. Particular attention is paid to the construction of finite total energy solutions. Any results of this kind may find application in the other fields in which an essential role is played by a wave-equation (like acoustics, geophysics, etc.). [PACS nos.: 03.50.De; 41.20;Jb; 83.50.Vr; 62.30.+d; 43.60.+d; 91.30.Fn; 04.30.Nk; 42.25.Bs; 46.40.Cd; 52.35.Lv. Keywords: Wave equations; Wave propagation; Localized beams; Superluminal waves; Coaxial cables; Bidirectional decomposition; Bessel beams; X-shaped waves; Maxwell equations; Microwaves; Optics; Special relativity; Coaxial metallic waveguides; Acoustics; Seismology; Mechanical waves; Elastic waves; Guided gravitational waves.]Comment: plain LaTeX file (22 pages), plus 15 figures; in press in Phys. Rev.