185 research outputs found

    Systematic errors in ground heat flux estimation and their correction

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    Incoming radiation forcing at the land surface is partitioned among the components of the surface energy balance in varying proportions depending on the time scale of the forcing. Based on a land-atmosphere analytic continuum model, a numerical land surface model, and field observations we show that high-frequency fluctuations in incoming radiation (with period less than 6 h, for example, due to intermittent clouds) are preferentially partitioned toward ground heat flux. These higher frequencies are concentrated in the 0–1 cm surface soil layer. Subsequently, measurements even at a few centimeters deep in the soil profile miss part of the surface soil heat flux signal. The attenuation of the high-frequency soil heat flux spectrum throughout the soil profile leads to systematic errors in both measurements and modeling, which require a very fine sampling near the soil surface (0–1 cm). Calorimetric measurement techniques introduce a systematic error in the form of an artificial band-pass filter if the temperature probes are not placed at appropriate depths. In addition, the temporal calculation of the change in the heat storage term of the calorimetric method can further distort the reconstruction of the surface soil heat flux signal. A correction methodology is introduced which provides practical application as well as insights into the estimation of surface soil heat flux and the closure of surface energy balance based on field measurements

    Modelling and observing urban climate in the Netherlands

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    Volgens de klimaatscenario’s van het KNMI uit 2006 zal de gemiddelde temperatuur in Nederland in de komende decennia verder stijgen. Hittegolven zullen naar verwachting vaker voorkomen en de intensiteit van met name zomerse buien kan toenemen. In steden zijn de gevolgen van de opwarming extra voelbaar, omdat de temperaturen er door het zogenoemde Urban Heat Island (UHI) effect veel hoger kunnen zijn dan in het omliggende gebied. Zulke periodes met hoge temperaturen gaan veelal gepaard met verslechterde luchtkwaliteit en droogte. Dit alles kan grote gevolgen hebben voor de leefbaarheid en de gezondheid van de bevolking in stedelijke gebieden. Veranderingen in de buienintensiteit beïnvloeden de waterhuishouding van de stad

    Quality control of CarboEurope flux data ? Part II: Inter-comparison of eddy-covariance software

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    International audienceAs part of the quality assurance and quality control activities within the CarboEurope-IP network, a comparison of eddy-covariance software was conducted. For four five-day datasets, CO2 flux estimates were calculated by seven commonly used software packages to assess the uncertainty of CO2 flux estimates due to differences in post-processing. The datasets originated from different sites representing different commonly applied instrumentation and different canopy structures to cover a wide range of realistic conditions. Data preparation, coordinate rotation and the implementation of the correction for high frequency spectral losses were identified as crucial processing steps leading to significant discrepancies in the CO2 flux results. The overall comparison indicated a good although not yet perfect agreement among the different software within 5?10% difference for 30-min CO2 flux values. Conceptually different ideas about the selection and application of processing steps were a main reason for the differences in the CO2 flux estimates observed. A balance should be aspired between scientific freedom on the one hand, in order to advance methodical issues, and standardisation of procedures on the other hand, in order to obtain comparable fluxes for multi-site synthesis studies

    Ruimtelijke analyse van het stadsklimaat in Rotterdam

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    Om een inzicht te verkrijgen in de opwarming van stedelijk gebied zijn ruimtelijk veel metingen nodig. Een mobiel meetplatform werd toegepast om langs verschillende trajecten de hitte overdag en ’s nachts in kaart te brengen. Belangrijkste resultaten uit de eerste verkenningen laten zien dat Rotterdam ’s nachts een aanzienlijk stedelijk hitte-eiland effect ontwikkelt gedurende zonnige dagen met weinig wind (verschil luchttemperatuur en buitengebied >7 °C). Overdag was het verschil in luchttemperatuur veel minder groot. ’s Ochtends werden zelfs lagere luchttemperaturen gemeten dan in het buitengebied. In de middag bleef de opwarming beperkt tot 2 °C en met name groene wijken blijven dan koeler. Opvallend was dat tijdens het warmste moment van de dag een park zelfs 2 °C koeler bleek dan het buitengebied. De koelste wijken waren de wat oudere laagbouwwijken met veel groen (zoals Kralingen)

    Record high solar irradiance in Western Europe during first COVID-19 lockdown largely due to unusual weather

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    Spring 2020 broke sunshine duration records across western Europe. The Netherlands recorded the highest surface irradiance since 1928, exceeding the previous extreme of 2011 by 13 %, and the diffuse fraction of the irradiance measured a record low percentage (38 %). The coinciding irradiance extreme and a reduction in anthropogenic pollution due to COVID-19 measures triggered the hypothesis that cleaner-than-usual air contributed to the record. Based on analyses of ground-based and satellite observations and experiments with a radiative transfer model, we estimate a 1.3 % (2.3 W m2^{-2}) increase in surface irradiance with respect to the 2010-2019 mean due to a low median aerosol optical depth, and a 17.6 % (30.7 W m2^{-2}) increase due to several exceptionally dry days and a very low cloud fraction overall. Our analyses show that the reduced aerosols and contrails due to the COVID-19 measures are far less important in the irradiance record than the dry and particularly cloud-free weather.Comment: 21 pages, 12 figures, submitted to Communications Earth and Environmen

    Towards green design guidelines for thermally comfortable streets

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    Creating thermally comfortable streetscapes is a rather new challenge for urban designers in The Netherlands and other countries with moderate climates. This is due to the lack of evidence based design guidelines. By combining research methods from micrometeorology and landscape architecture, we work on the development of such guidelines. For that purpose, we investigated physical and psychological impacts of street greenery on thermal comfort in three street types with varying vegetation density

    Pressure-Corrected Carotid Stiffness and Young's Modulus: Evaluation in an Outpatient Clinic Setting

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    Background: Conventional measures for assessing arterial stiffness are inherently pressure dependent. Whereas statistical pressure adjustment is feasible in (larger) populations, it is unsuited for the evaluation of an individual patient. Moreover, statistical "correction"for blood pressure may actually correct for: (i) the acute dependence of arterial stiffness on blood pressure at the time of measurement; and/or (ii) the remodeling effect that blood pressure (hypertension) may have on arterial stiffness, but it cannot distinguish between these processes. METHODS: We derived - assuming a single-exponential pressure-diameter relationship - 3 theoretically pressure-independent carotid stiffness measures suited for individual patient evaluation: (i) stiffness index β0, (ii) pressure-corrected carotid pulse wave velocity (cPWVcorr), and (iii) pressure-corrected Young's modulus (Ecorr). Using linear regression analysis, we evaluated in a sample of the CATOD study cohort changes in mean arterial pressure (ΔMAP) and comparatively the changes in the novel (Δβ0, ΔcPWVcorr, and ΔEcorr) as well as conventional (ΔcPWV and ΔE) stiffness measures after a 2.9 ± 1.0-year follow-up. RESULTS: We found no association between ΔMAP and Δβ0, ΔcPWVcorr, or ΔEcorr. In contrast, we did find a significant association between ΔMAP and conventional measures ΔcPWV and ΔE. Additional adjustments for biomechanical confounders and traditional risk factors did neither materially change these associations nor the lack thereof. Conclusions: Our newly proposed pressure-independent carotid stiffness measures avoid the need for statistical correction. Hence, these measures (β0, cPWVcorr, and Ecorr) can be used in a clinical setting for (i) patient-specific risk assessment and (ii) investigation of potential remodeling effects of (changes in) blood pressure on intrinsic arterial stiffness

    Developmental neurotoxicity of environmentally relevant pharmaceuticals and mixtures thereof in a zebrafish embryo behavioural test

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    Humans are exposed daily to complex mixtures of chemical substances via food intake, inhalation, and dermal contact. Developmental neurotoxicity is an understudied area and entails one of the most complex areas in toxicology. Animal studies for developmental neurotoxicity (DNT) are hardly performed in the context of regular hazard studies, as they are costly and time consuming and provide only limited information as to human relevance. There is a need for a combination of in vitro and in silico tests for the assessment of chemically induced DNT in humans. The zebrafish (Danio rerio) embryo (ZFE) provides a powerful model to study DNT because it shows fast neurodevelopment with a large resemblance to the higher vertebrate, including the human system. One of the suitable readouts for DNT testing in the zebrafish is neurobehaviour (stimulus-provoked locomotion) since this provides integrated information on the functionality and status of the entire nervous system of the embryo. In the current study, environmentally relevant pharmaceuticals and their mixtures were investigated using the zebrafish light-dark transition test. Zebrafish embryos were exposed to three neuroactive compounds of concern, carbamazepine (CBZ), fluoxetine (FLX), and venlafaxine (VNX), as well as their main metabolites, carbamazepine 10,11-epoxide (CBZ 10,11E), norfluoxetine (norFLX), and desvenlafaxine (desVNX). All the studied compounds, except CBZ 10,11E, dose-dependently inhibited zebrafish locomotor activity, providing a distinct behavioural phenotype. Mixture experiments with these pharmaceuticals identified that dose addition was confirmed for all the studied binary mixtures (CBZ-FLX, CBZ-VNX, and VNX-FLX), thereby supporting the zebrafish embryo as a model for studying the cumulative effect of chemical mixtures in DNT. This study shows that pharmaceuticals and a mixture thereof affect locomotor activity in zebrafish. The test is directly applicable in environmental risk assessment; however, further studies are required to assess the relevance of these findings for developmental neurotoxicity in humans

    Identification and manipulation of tumor associated macrophages in human cancers

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    Evading immune destruction and tumor promoting inflammation are important hallmarks in the development of cancer. Macrophages are present in most human tumors and are often associated with bad prognosis. Tumor associated macrophages come in many functional flavors ranging from what is known as classically activated macrophages (M1) associated with acute inflammation and T-cell immunity to immune suppressive macrophages (M2) associated with the promotion of tumor growth. The role of these functionally different myeloid cells is extensively studied in mice tumor models but dissimilarities in markers and receptors make the direct translation to human cancer difficult. This review focuses on recent reports discriminating the type of infiltrating macrophages in human tumors and the environmental cues present that steer their differentiation. Finally, immunotherapeutic approaches to interfere in this process are discussed
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