Eco-Efficiency of Forage Production in Northern Germany

A 2-year field experiment was conducted at two sites in Schleswig-Holstein, northern Germany, to quantify and evaluate the carbon footprint of arable forage cropping systems (continuous silage maize, maize-wheat-grass rotation, perennial ryegrass ley) as affected by N fertilizer type and N amount. Total greenhouse gas emission showed a linear increase with N application, with mineral N supply resulting in a higher slope. Product carbon footprint ranged between -66 and 119 kg CO2eq/(GJ NEL) and revealed a quadratic or linear response to fertilizer N input, depending on the cropping system. At N input required for achieving maximum energy yield, perennial ryegrass caused lower emission per product unit than continuous maize or the maize-wheat-grass rotation. The data indicate potential for sustainable intensification when crop management options are adopted to increase resource use efficiency

Lachgasemission und Nitratauswaschung verschiedener Futterproduktionssysteme in Abhängigkeit von der Vornutzung

Intensified agriculture is often associated with nitrous oxide (N2O) emissions and nitrate (NO3) leaching losses into groundwater due to high application rates of N-fertilizer, increasing maize cultivation and ploughing up permanent grassland. N2O is an important anthropogenic greenhouse gas and agriculture is one of the main polluters. NO3 leaching endangers groundwater quality. In a field experiment on the organically managed farm “Lindhof” in Northern Germany three different forage production systems (1. crop rotation, 2. continuous silage maize 3. permanent grassland) were established parallelly after a) ploughing up permanent grassland and b) longtime arable use. N2O emissions were measured weekly over the two-year experimental period. Soil water samples were taken over the leaching season (Oct-Mar) once a week and analysed for N-content. The production systems “crop rotation” and “continuous maize” showed significant higher amounts of N2O emissions and NO3 leaching than the newly established or resown grassland. In the system “crop rotation”, maize after grass-clover had the highest emissions, because of high N-mineralization of clover residues, both during and after growing season. Long-term cropping history and manure application had no significant effects, but on plots established on former grassland, emissions and leaching tended to be higher

Yield Progress in Forage Maize in NW Europe—Breeding Progress or Climate Change Effects?

Yield increases in forage maize (Zea mays L.) in NW Europe over time are well documented. The driving causes for these, however, remain unclear as there is little information available regarding the role of plant traits triggering this yield progress. Ten different hybrids from the same maturity group, which have typically been cultivated in Northwest Germany from 1970 to recent and are thus representing breeding progress over four decades, were selected for a 2-year field study in northern Germany. Traits that were investigated included leaf area index, leaf architecture, photosynthesis, radiation use efficiency, root mass, root length density, and turnover. Based on a mixed model analysis with these traits as co-variates, parameters related to leaf characteristics, in particular the number and length of leaves, the radiation use efficiency, and the leaf orientation, were identified as most influential on the yield progress (0.13 tons ha-1 year-1). In contrast to our hypothesis, root biomass only increased negligibly in newer hybrids compared to older ones, confirming the ‘functional equilibrium’ theory for high input production systems. Due to an abundance of nutrients and water in such high input systems, there is no incentive for breeders to select for carbon partitioning toward the rooting system. Breeding evidence to increase forage quality were also negligible, with no change in cob starch concentration, forage digestibility, nor NDF content and NDF digestibility. The observed increase in yield over the last four decades is due to a combination of increased temperature sums (~240 GDD within 40 years), and a higher radiation interception and radiation use efficiency. This higher radiation interception was driven by an increased leaf area index, with a higher number of leaves (16 instead of 14 leaves within 40 years) and longer leaves of newer compared to older hybrids. Future selection and adaptation of maize hybrids to changing environmental conditions are likely to be the key for high productivity and quality and for the economic viability of maize growing and expansion in Northern Europe

N-Umsatz, Spurengasemissionen und Produktivität von Fruchtfolgen zur Biogasproduktion in einer Kalkmarsch Schleswig-Holsteins

Aufgrund des bisher wenig untersuchten Agrarlandschaftsraumes als auch neuartiger Biogasgärreste ist der Effekt der Biogasnutzung auf den Stoffhaushalt von Marschstandorten schwer zu quantifizieren. Auf einem noch nicht entkalkten Marschstandort Nordfries-lands, Schleswig-Holstein, wurden in einem Parzellenversuch mehrjährige Untersuchungen zur N-Düngewirksamkeit und Spurengasemissionen (N2O, NH3) bei Düngung mit Mineraldünger (KAS) und Biogasgärresten durchgeführt. Die N-Dünger wurden zur Produktion von Silomais, Weidelgras und GPS-Weizen als Biogassubstrat genutzt. Biogas-gärreste wurden mit Schleppschläuchen ausgebracht. Bei Verwendung des Mineraldüngers erzielten Maismonokultur, Ackergras sowie eine Fruchtfolge (Mais-Weizen-Welsches Weidelgras) etwa gleich hohe Erträge (ca. 30 t TM ha 1 2a-1). Bei Weizen und Ackergras führte die Düngung mit Biogasgärresten zu deutlich reduzierten Erträgen. NH3-Emissionen lagen aufgrund hoher Windgeschwin- digkeiten höher als in anderen Regionen Schleswig-Holsteins, wobei Ackergras bei weitem die höchsten (80 kg N ha-1 2a-1) und Maismonokultur die geringsten (20 kg N ha-1 2a-1) kumulierten Verluste aufwies. Ohne signifikante Unterschiede zwischen den N-Düngern lagen kumulierte N2O-Emissionen mit 1–5 kg N ha-1 a-1 trotz beträchtlicher N-Aufwand-mengen und des tonreichen Bodens relativ niedrig

N-Umsatz und Spurengasemissionen typischer Biomassefruchtfolgen zur Biogaserzeugung in Norddeutschland

Im Rahmen des Verbundprojektes Biogas-Expert an der CAU-Kiel wurden an zwei Standorten Schleswig-Holsteins veschiedene Fruchtfolgen zur Bereitstellung von Biogassubstraten unter Verwendung von Biogasgüllen als N-Dünger durchgeführt. Maismonokultur wies die höchsten Trockenmasseerträge auf, wobei keine signifikanten Unterschiede in den Erträgen zwischen Biogasgärresten, organischen N-Düngern und mineralischen Düngern ermittelt wurden. Während in Bezug auf die N-Düngeform bei N2O- und Nitratauswaschungsverlusten kein Einfluss der N-Form auf die Höhe der Verluste festgestellt wurde, war die Düngung mit Biogasgüllen mit signifikant erhöhten NH3-Verlusten verknüpft. Eine abschließende Bewertung der Produktionssysteme ist erst durch Analyse der experimentellen Ergebnisse mit einem Systemmodell möglich

Assessing nitrous oxide emissions and productivity of cropping systems for biogas production using digestate and mineral fertilisation in a coastal marsh site

Significant greenhouse gas emissions during substrate cultivation reduces the potential environmental benefits of biogas production. This study investigates the productivity of different cropping systems and their environmental impact in terms of nitrous oxide (N2O) emissions under the environmental conditions of the coastal marsh regions (Northern Germany) with heavy clay soils, in a 2-year field trial (April 2009-March 2011). Treatments included four cropping systems (perennial ryegrass (Lolium perenne, PR) ley, continuous maize (Zea mays), a rotation (CR1) of spring wheat (Triticum aestivum), Italian ryegrass (Lolium multiflorum, IR) and maize, and a rotation (CR2) of maize, winter wheat and IR; two sources of N (nitrogen) fertilizers (calcium ammonium nitrate, and biogas residue (BR)), and three levels of N fertilizer applications (control, moderate, high). Nitrous oxide emissions were determined for the unfertilized and highly fertilized cropping systems comprising PR ley, CR1 and CR2. Cumulative annual N2O emissions varied across the treatments, ranging from 0.82 to 3.4 kg N2O-N ha−1 year−1. Under high N fertilizer applications, PR ley incurred higher N2O-N losses compared to other tested cropping systems, and IR cover crop caused relatively high N2O-N emissions in a short vegetation period. The study observed wide range of yield-scaled emissions (0.00–5.60 kg N2O-N (Mg DM)−1) for different crops, emphasizing the variability in N2O emissions linked to cropping systems. The N2O-N emission factors for the three cropping systems were found to be low to moderate for all treatments, ranging from 0.03% to 0.53% compared to IPCC default Tier 1 N2O-N EFs. The lower emissions in the study were associated with prolonged high soil moisture conditions (water filled pore space >70%.), indicated by its negative correlation with N2O-N fluxes. Low dry matter and N yield of PR and of the wheat-IR sequence after BR application compared to other crops indicated a low N use efficiency. The estimation of N2O-N emissions based on N surplus was not promising specifically for the coastal study site where high groundwater level and organic matter in the soils were the predominant drivers for N2O-N emissions

Determinants of female sexual function in inflammatory bowel disease: a survey based cross-sectional analysis

<p>Abstract</p> <p>Background</p> <p>Sexual function is impaired in women with inflammatory bowel disease (IBD) as compared to normal controls. We examined disease specific determinants of different aspects of low sexual function.</p> <p>Methods</p> <p>Women with IBD aged 18 to 65 presenting to the university departments of internal medicine and surgery were included. In addition, a random sample from the national patients organization was used (separate analyses). Sexual function was assessed by the Brief Index of Sexual Function in Women, comprising seven different domains of sexuality. Function was considered impaired if subscores were < -1 on a z-normalized scale. Results are presented as age adjusted odds ratios with 95% CI based on multiple logistic regression.</p> <p>Results</p> <p>336 questionnaires were included (219 Crohn's disease, 117 ulcerative colitis). Most women reported low sexual activity (63%; 17% none at all, 20% moderate or high activity). Partnership satisfaction was high in spite of low sexual interest in this group. Depressed mood was the strongest predictor of low sexual function scores in all domains. Urban residency and higher socioecomic status had a protective effect. Disease activity was moderately associated with low desire (OR 1.8, 95% CI 1.0 to 3.2). Severity of the disease course impacted most on intercourse frequency (OR 2.3, 95% CI 1.4 to 4.7). Lubrication problems were more common in smokers (OR 2.5, 95% CI 1.3 to 5.1).</p> <p>Conclusion</p> <p>Mood disturbances and social environment impacted more on sexual function in women with IBD than disease specific factors. Smoking is associated with lubrication problems.</p

Inhibitors of dihydroorotate dehydrogenase cooperate with molnupiravir and N4-hydroxycytidine to suppress SARS-CoV-2 replication

Funding Information: We thank Thorsten Wolff, Daniel Bourquain, Jessica Schulz, and Christian Mache from the Robert-Koch Institute and Martin Beer from the Friedrich Loeffler Institute (FLI) for providing isolates of SARS-CoV-2 variants. We thank Anna Kraft and Gabriele Czerwinski (both FLI) for support in the preparation of samples for pathology, and Catherine Hambly (University of Aberdeen) for help with daily energy expenditure measurements. We would like to thank Cathrin Bierwirth (University Medical Center Göttingen), Isabell Schulz, Anne-Kathrin Donner, and Frank-Thorben Peters for excellent technician assistance and Jasmin Fertey and Alexandra Rockstroh for providing the virus stocks for the mice experiment (Fraunhofer Institute IZI Leipzig). We acknowledge support by the Open Access Publication Funds of the Göttingen University. KMS was a member of the Göttingen Graduate School GGNB during this work. This work was funded by the COVID-19 Forschungsnetzwerk Niedersachsen (COFONI) to MD, by the Federal Ministry of Education and Research Germany ( Bundesministerium für Bildung und Forschung; BMBF ; OrganSARS , 01KI2058 ) to SP and TM, and by a grant of the Max Planck Foundation to DG. Declaration of interests AS, HK, EP, and DV are employees of Immunic AG and own shares and/or stock-options of the parent company of Immunic AG, Immunic Inc. Some of the Immunic AG employees also hold patents for the Immunic compounds described in this manuscript (WO2012/001,148, WO03006425). KMS, AD, and MD are employees of University Medical Center Göttingen, which has signed a License Agreement with Immunic AG covering the combination of DHODH inhibitors and nucleoside analogs to treat viral infections, including COVID-19 (inventors: MD, KMS, and AD). The other authors declare no conflict of interest.Peer reviewedPublisher PD