94 research outputs found
A gyermek 14 (1920) 01-05
A gyermek
A Magyar Gyermektanulmányi Társaság közlönye
14. évfolyam , 1-5. szám
Budapest, 1920.
A folyóirat 1908-ig a Gyermekvédelmi lap mellékleteként, 1909-től mint önálló lap jelent meg
Im Auftrag des Petrus – Apostolische Legenden und Gründungsmythen im Vergleich
Lehrstücke: Gesammelte Beiträge fortgeschrittener Studierender der Friedrich-Alexander-Universität Erlangen-Nürnberg aus der Forschungsübung „Im Auftrag des Petrus – Apostoli-sche Legenden und Gründungsmythen im Vergleich“, zusammengestellt und betreut von den Übungsleiterinnen Dr. Claudia Alraum und Dr. Cornelia Scherer
An online platform supporting the analysis of water adaptation measures in the Alps
Climate change may result in reduced water supply from the Alps - an important water resource for Europe. This paper presents a multilingual platform that combines spatial and multi-criteria decision-support tools to facilitate stakeholder collaboration in the analysis of water management adaptation options. The platform has an interactive map interface that allows participants to select a location of their interest within the Alpine Arc. By utilising the decision-support tool, stakeholders can identify suitable adaptation solutions for different geographical units, according to their experience and preference. The platform was used to involve experts across Alpine borders, domains and decision-making levels, as well as a group of university students. The experts favoured the planning instruments for saving water, while the students inclined towards the measures that would improve water conservation. The initial results confirmed the suitability of the platform for future involvement of decision-makers in spatio-temporal analyses of adaptation pathways in the Alps
Aptamers for pharmaceuticals and their application in environmental analytics
Aptamers are single-stranded DNA or RNA oligonucleotides, which are able to bind with high affinity and specificity to their target. This property is used for a multitude of applications, for instance as molecular recognition elements in biosensors and other assays. Biosensor application of aptamers offers the possibility for fast and easy detection of environmental relevant substances. Pharmaceutical residues, deriving from human or animal medical treatment, are found in surface, ground, and drinking water. At least the whole range of frequently administered drugs can be detected in noticeable concentrations. Biosensors and assays based on aptamers as specific recognition elements are very convenient for this application because aptamer development is possible for toxic targets. Commonly used biological receptors for biosensors like enzymes or antibodies are mostly unavailable for the detection of pharmaceuticals. This review describes the research activities of aptamer and sensor developments for pharmaceutical detection, with focus on environmental applications
Stable transmission of reversible modifications: maintenance of epigenetic information through the cell cycle
Even though every cell in a multicellular organism contains the same genes, the differing spatiotemporal expression of these genes determines the eventual phenotype of a cell. This means that each cell type contains a specific epigenetic program that needs to be replicated through cell divisions, along with the genome, in order to maintain cell identity. The stable inheritance of these programs throughout the cell cycle relies on several epigenetic mechanisms. In this review, DNA methylation and histone methylation by specific histone lysine methyltransferases (KMT) and the Polycomb/Trithorax proteins are considered as the primary mediators of epigenetic inheritance. In addition, non-coding RNAs and nuclear organization are implicated in the stable transfer of epigenetic information. Although most epigenetic modifications are reversible in nature, they can be stably maintained by self-recruitment of modifying protein complexes or maintenance of these complexes or structures through the cell cycle
Environmental GIS and Applications. GI_Forum|GI_Forum 2015 – Geospatial Minds for Society|
An online method database for mapping and assessing ecosystem services
Since the foundation of the ecosystem services concept in the ninetieth of the last century (Costanza et al. 1998, Costanza et al. 1997, de Groot 1992), many methods to map and assess ecosystem services have been developed and applied to policy and business questions worldwide. While many flexible methods exist at different spatial scales and ecosystem types, Jax et al. (2018) express the difficulty in choosing and applying the correct method to the right topic of interest. To enable a selection of appropriate methods, Harrison et al. (2018) developed a decision tree approach. However, Dunford et al. (2018) argue that often not a single method but a combination of methods are required for appropriate decision-making in real world situations. Thus, applying the concept of ecosystem services in practice is challenging, especially at institutional level (Saarikoski et al. 2018). This hampers comparability, applicability and transferability of ecosystem services assessments and related mapping applications across scales and European regions. It also impedes a solid overview of existing methods suitable for use at different scales in different biomes and types of ecosystems. These challenges require a consistent knowledge capitalisation infrastructure, where information is synthesised in a publicly accessible portal to enable a consistent description of different ecosystem conditions and the services they provide.
Going beyond the previously mentioned challenges requires a flexible methodology for assessing and mapping ecosystem services. The Horizon 2020 project ESMERALDA (Enhancing ecoSysteM sERvices mApping for poLicy and Decision mAking) developed this methodology and implemented it into the "MAES explorer"*5 and the "MAES Methods Explorer*1 (MME)". The MME complements previous developments from the EU projects OpenNESS*2 and OPERAs*3. In contrast to the OPPLA*4 case-study-finder with case study areas and accompanied study area booklets and descriptions, MME focuses on methods for mapping and assessing ecosystem services and links those to selected literature and case studies. Additionally, MME provides a comprehensive and publicly searchable collection of peer-reviewed journal references and grey literature about mapping and assessing ecosystem services in Europe. This compilation is cross-related with the case study booklets produced by the ESMERALDA project and particularly methods, which are specifically used to assess and map particular ecosystem services within the case study area. Thus, searching for and filtering of particular case study areas, (related) literature references and/or methods is possible. Santos-Martin et al. (2018) provide the detailed description about the scientific procedure behind the MME tool described here
A Multi-purpose Weather Forecast Model for the Mondsee Catchment. GI_Forum|GI_Forum 2015 – Geospatial Minds for Society|
In the course of climate change, extreme weather events and their consequences are likely to increase in the next decades. To enable publicly available predictions preceding an event, we operate an Advanced Research Weather Research & Forecasting (WRF-ARW) limited area model to ensure pro-active mitigation strategies before the start of a storm event. To demonstrate the actual model performance for multiple stakeholders, we compared the prediction with publicly available measurements from nearby stations recorded during the extreme event, starting in the evening of October 22nd, 2014 in the Mondsee catchment. In the beginning, the model prediction highly underestimated the rainfall at most of the weather stations. However, the prediction accuracy increased from 54 to 30 hours in advance to the event. For the Mondsee weather station located inside the catchment, the predictions 30 and 6 hours in advance had an accuracy of -32% and -28%, respectively. However, the prediction was challenged by extremely unstable weather conditions. Nevertheless, the prediction forecasted an event where flooding was a very likely consequence, considering the spatial-temporal amount of rainfall predicted. Thus, an early warning message to responsible stakeholders would have been appropriate for pro-active mitigation action in this case
Visualization of 3D Hydrogeological Data in the Web. GI_Forum 2014 – Geospatial Innovation for Society|
New Zealand's groundwater resources are inadequately understood to effectively support an integrated and sustainable freshwater management. To appropriately characterise the groundwater aquifers, a lot of environmental data are required; among them (hydro- )geological datasets. Usually, proprietary software products are used to establish, visualise and analyse the geological underground. This prevents a broad and public distribution of information to those who need it. In this manuscript we demonstrate a framework to enable a web-based (platform independent) retrieval and visualisation of three-dimensional information via the web browser. We link distributed data and processing services to prepare an on-demand 3D visualisation of geological and hydrological data
Visualization of 3D Hydrogeological Data in the Web. GI_Forum 2014 – Geospatial Innovation for Society|
New Zealand's groundwater resources are inadequately understood to effectively support an integrated and sustainable freshwater management. To appropriately characterise the groundwater aquifers, a lot of environmental data are required; among them (hydro- )geological datasets. Usually, proprietary software products are used to establish, visualise and analyse the geological underground. This prevents a broad and public distribution of information to those who need it. In this manuscript we demonstrate a framework to enable a web-based (platform independent) retrieval and visualisation of three-dimensional information via the web browser. We link distributed data and processing services to prepare an on-demand 3D visualisation of geological and hydrological data
- …