2,226 research outputs found

    Billy Elliot The Musical: visual representations of working-class masculinity and the all-singing, all-dancing bo[d]y

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    According to Cynthia Weber, ‘[d]ance is commonly thought of as liberating, transformative, empowering, transgressive, and even as dangerous’. Yet ballet as a masculine activity still remains a suspect phenomenon. This paper will challenge this claim in relation to Billy Elliot the Musical and its critical reception. The transformation of the visual representation of the human body on stage (from an ephemeral existence to a timeless work of art) will be discussed and analysed vis-a-vis the text and sub-texts of Stephen Daldry’s direction and Peter Darling’s choreography. The dynamics of working-class masculinity will be contextualised within the framework of the family, the older female, the community, the self and the act of dancing itself

    Classifying the precancers: A metadata approach

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    BACKGROUND: During carcinogenesis, precancers are the morphologically identifiable lesions that precede invasive cancers. In theory, the successful treatment of precancers would result in the eradication of most human cancers. Despite the importance of these lesions, there has been no effort to list and classify all of the precancers. The purpose of this study is to describe the first comprehensive taxonomy and classification of the precancers. As a novel approach to disease classification, terms and classes were annotated with metadata (data that describes the data) so that the classification could be used to link precancer terms to data elements in other biological databases. METHODS: Terms in the UMLS (Unified Medical Language System) related to precancers were extracted. Extracted terms were reviewed and additional terms added. Each precancer was assigned one of six general classes. The entire classification was assembled as an XML (eXtensible Mark-up Language) file. A Perl script converted the XML file into a browser-viewable HTML (HyperText Mark-up Language) file. RESULTS: The classification contained 4700 precancer terms, 568 distinct precancer concepts and six precancer classes: 1) Acquired microscopic precancers; 2) acquired large lesions with microscopic atypia; 3) Precursor lesions occurring with inherited hyperplastic syndromes that progress to cancer; 4) Acquired diffuse hyperplasias and diffuse metaplasias; 5) Currently unclassified entities; and 6) Superclass and modifiers. CONCLUSION: This work represents the first attempt to create a comprehensive listing of the precancers, the first attempt to classify precancers by their biological properties and the first attempt to create a pathologic classification of precancers using standard metadata (XML). The classification is placed in the public domain, and comment is invited by the authors, who are prepared to curate and modify the classification

    Effect of Naproxen on Gastroesophageal Reflux and Esophageal Function: A Randomized, Double-Blind, Placebo-Controlled Study

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/75450/1/j.1572-0241.1995.tb09312.x.pd

    Measurements of Sunyaev-Zel'dovich Effect Scaling Relations for Clusters of Galaxies

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    We present new measurements of the Sunyaev-Zel'dovich (SZ) effect from clusters of galaxies using the Sunyaev-Zel'dovich Infrared Experiment (SuZIE II). We combine these new measurements with previous cluster observations with the SuZIE instrument to form a sample of 15 clusters of galaxies. For this sample we calculate the central Comptonization, y, and the integrated SZ flux decrement, S, for each of our clusters. We find that the integrated SZ flux is a more robust observable derived from our measurements than the central Comptonization due to inadequacies in the spatial modelling of the intra-cluster gas with a standard Beta model. This is highlighted by comparing our central Comptonization results with values calculated from measurements using the BIMA and OVRO interferometers. On average, the SuZIE calculated central Comptonizations are approximately 60% higher in the cooling flow clusters than the interferometric values, compared to only approximately 12% higher in the non-cooling flow clusters. We believe this discrepancy to be in large part due to the spatial modelling of the intra-cluster gas. From our cluster sample we construct y-T and S-T scaling relations. The y-T scaling relation is inconsistent with what we would expect for self-similar clusters; however this result is questionable because of the large systematic uncertainty in the central Comptonization. The S-T scaling relation has a slope and redshift evolution consistent with what we expect for self-similar clusters with a characteristic density that scales with the mean density of the universe. We rule out zero redshift evolution of the S-T relation at 90% confidence.Comment: Accepted to Astrophysical Journal. 52 pages, 14 tables, 7 figures ;replaced to match ApJ accepted versio

    In a distinguishing spacetime the horismos relation generates the causal relation

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    It is proved that in a distinguishing spacetime the horismos relation E^+=J^+\I^+ generates the causal relation J^+. In other words two causally related events are joined by a chain of horismotically related events, or again, the causal relation is the smallest transitive relation containing the horismos relation. The result is sharp in the sense that distinction can not be weakened to future or past distinction. Finally, it is proved that a spacetime in which the horismos relation generates the causal relation is necessarily non-total imprisoning.Comment: 7 pages, Latex2

    Nonparametric nonlinear model predictive control

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    Model Predictive Control (MPC) has recently found wide acceptance in industrial applications, but its potential has been much impeded by linear models due to the lack of a similarly accepted nonlinear modeling or databased technique. Aimed at solving this problem, the paper addresses three issues: (i) extending second-order Volterra nonlinear MPC (NMPC) to higher-order for improved prediction and control; (ii) formulating NMPC directly with plant data without needing for parametric modeling, which has hindered the progress of NMPC; and (iii) incorporating an error estimator directly in the formulation and hence eliminating the need for a nonlinear state observer. Following analysis of NMPC objectives and existing solutions, nonparametric NMPC is derived in discrete-time using multidimensional convolution between plant data and Volterra kernel measurements. This approach is validated against the benchmark van de Vusse nonlinear process control problem and is applied to an industrial polymerization process by using Volterra kernels of up to the third order. Results show that the nonparametric approach is very efficient and effective and considerably outperforms existing methods, while retaining the original data-based spirit and characteristics of linear MPC

    The impact of neighbourhood walkability on the effectiveness of a structured education programme to increase objectively measured walking

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    Background: Incorporating physical activity into daily activities is key for the effectiveness of lifestyle education interventions aimed at improving health outcomes; however, consideration of the environmental context in which individuals live is not always made. Walkability is a characteristic of the physical environment, and may be a potential facilitator to changing physical activity levels.  Methods: Using data collected during the Walking Away from Diabetes randomised controlled trial, we examined the association between the walkability of the home neighbourhood and physical activity of participants. We also determined whether home neighbourhood walkability of participants was associated with the intervention effect of the education programme.  Results: Data from 706 participants were available for analysis. Neighbourhood walkability was not significantly associated with any of the physical activity measures at baseline, or at 12, 24 or 36 months following the intervention (p>0.05 for all). There was no association between walkability and change in purposeful steps/ day from baseline to 36months in the usual care or intervention arm; 25.77 (-99.04, 150.58) and 42.97 (-327.63, 413.45) respectively.  Conclusion: Neighbourhood walkability appeared to have no association with objectively-measured physical activity in this population. Furthermore, the walkability of participant’s neighbourhood did not influence the effectiveness of a lifestyle programme

    A discrete, unitary, causal theory of quantum gravity

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    A discrete model of Lorentzian quantum gravity is proposed. The theory is completely background free, containing no reference to absolute space, time, or simultaneity. The states at one slice of time are networks in which each vertex is labelled with two arrows, which point along an adjacent edge, or to the vertex itself. The dynamics is specified by a set of unitary replacement rules, which causally propagate the local degrees of freedom. The inner product between any two states is given by a sum over histories. Assuming it converges (or can be Abel resummed), this inner product is proven to be hermitian and fully gauge-degenerate under spacetime diffeomorphisms. At least for states with a finite past, the inner product is also positive. This allows a Hilbert space of physical states to be constructed.Comment: 38 pages, 9 figures, v3 added to exposition and references, v4 expanded prospects sectio

    Comparative studies on the structure of an upland African stream ecosystem

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    Upland stream systems have been extensively investigated in Europe, North America and Australasia and many of the central ideas concerning their function are based on these systems. One central paradigm, the river continuum concept is ultimately derived from those North American streams whose catchments remain forested with native vegetation. Streams of the tropics may or may not fit the model. They have been little studied. The Amani Nature Reserve in the East Usambara Mountains of north-eastern Tanzania offers an opportunity to bring these naturally forested systems to the attention of the ecological community. This article describes a comparison made between two lengths of the River Dodwe in this area. The work was carried out by a group of postgraduate students from eighteen European and African countries with advice from five staff members, as part of a course organised by the Tropical Biology Association. Rigorous efforts were made to standardise techniques, in a situation where equipment and laboratory facilities were very basic, through a management structure and deliberate allocation of work to specialists in each area.The article offers a summary of invertebrate communities found in the stream and its biomass. Crabs seem to be the key organism in both sections of the streams
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