2,507 research outputs found
Competition and economic performance
Onderzoek naar het aandeel van concurrentie bij sector prestatie aan de hand van twee tijdsperioden; het verleden (1988 - 1999) en de toekomst (2001-2012). Voor dit onderzoek is een model (MOCO) ontwikkeld om de effecten van turbulentie en concentratie van economische prestaties van sectoren te analyseren.
Characterization of Yersinia Pseudotuberculosis Abiotic Stress Responses
Bacteria require optimal growth conditions in order to thrive. However, stress factors such as cold and oxidation can attribute to the pathogenecity of a species. Ribonuclease E ( RNase E) is a component of the multicomplex protein, the degradosome, which is inclusive of: enolase (a glycolytic enzyme), and RhlB helicase, and 3\u27 -5\u27 exoribonuclease polynucleotide phosphorylase (PNPase). The microbiological model organism, E. coli, is attributed to first indicating the presence of microdomain PNPase in the degradosome. However, the species of interest in this study is Yersinia pseudotuberculosis (YPT) due to its affinity to proliferate and sustain in said abiotic stress environments unlike its enterobacteriaceae counterpart. YPT exposed to oxidative stress need degradosome assembly therefore it is degradosome-dependent. Conversely, the cold growth mechanism of PNPase in YPT is degradosome-independent
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In vitro plant regeneration and Agrobacterium tumefaciens-mediated transformation of Datura stramonium (Solanaceae).
Premise of the Study:Datura stramonium is a pharmacologically and evolutionarily important plant species in the family Solanaceae. Stable transformation methodology of this species would be advantageous for future genetic studies. Methods:In vitro plant regeneration and Agrobacterium tumefaciens-mediated transformation techniques were developed for D. stramonium based on methods reported for tomato. A binary vector containing pAtUBQ10::erGFP was used for transformation. Results:We recovered primary transformants harboring the green fluorescent protein (GFP) transgene that resulted in expression of fluorescence in all tissues analyzed. Transformants were allowed to self-pollinate, and two of five progeny contained the GFP transgene and displayed fluorescence identical to the primary transformants. Discussion:We have demonstrated the first stable transformation in the genus Datura. This is a key first step to study the genetic basis of traits in this evolutionarily interesting species
National consultation workshop on private sector participation in animal health services in Kenya: Workshop report
From Access to Adherence: The Challenges of Antiretroviral Treatment: Studies from Botswana, Tanzania and Uganda
The real-time measurement of wear using ultrasonic reflectometry
Ultrasonic reflectometry is commonly used in the fields of non-destructive testing (NDT) for crack detection, wall thickness monitoring and medical imaging. A sound wave is emitted through the material using a piezoelectric transducer. This waveform travels through the host medium at a constant speed and is either partially or fully reflected at an interface. The reflected wave is picked up by the same sensor; the signal is then amplified and digitised. If the speed that sound travels through a host medium is known as well as the time this takes, the thickness of the material can be established using the speed, distance and time relationship.
Previous work has concluded that the ultrasonic method is too inaccurate to measure wear due to the errors caused by temperature, vibration and the experimental arrangement. This body of work looks at methods to minimise these errors, particularly the inaccuracies introduced from the change in temperature caused by change of acoustic velocity and the thermal expansion of the material, which can be significant in many applications. Numerous case studies are presented using the technique in both laboratory and industrial environments using low cost retro-fittable sensors and small form electronics
IMPACT ASSESSMENT OF ENHANCED EXPOSURE FROM NATURALLY OCCURRING RADIOACTIVE MATERIALS (NORM) WITHIN LCA
The potential impact of ionising radiation from enhanced exposure to Naturally Occurring Radioactive Materials (NORM) to humans and the environment is not currently accounted for sufficiently in Life Cycle Assessment (LCA). Here we present midpoint and endpoint characterisation factors resulting from the implementation of impact assessment models for human health and ecosystems for NORM exposure. These models build upon existing fate, exposure and effect models from the LCA and radiological literature. The newly developed models are applied to a theoretical study of the utilisation of bauxite residue, a by-product of alumina processing enriched in natural radionuclides, in building materials. The ecosystem models have significant sensitivity to uncertainties surrounding the differential environmental fate of parent and daughter radionuclides that are produced as a part of decay chains, and to assumptions regarding long term releases from landfill sites. However, conservative results for environmental exposure suggest that in addition to landfill of materials, power consumption (burning coal and mining uranium) is a potentially significant source of radiological impact to the environment. From a human perspective, exposure to NORM in the use phase of building materials is the dominant source of impact, with environmental releases of nuclides playing a comparatively minor role. At an endpoint level, the impact of NORM exposure is highly significant in comparison to other impact categories in the area of protection of human health. This highlights the importance within LCA of having sufficient impact assessment models to capture all potential impacts, such that issues of burden shifting between impact measures can be captured, interpreted and resolved in the optimisation of product systems.https://doi.org/10.1016/j.jclepro.2017.11.13
Creating an innovation ecosystem for rapid diagnostic tests for livestock to support sustainable antibiotic use
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Social Exclusion: More Important to Human Females Than Males
Theoretical models based on primate evidence suggest that social structure determines the costs and benefits of particular aggressive strategies. In humans, males more than females interact in groups of unrelated same-sex peers, and larger group size predicts success in inter-group contests. In marked contrast, human females form isolated one-on-one relationships with fewer instrumental benefits, so social exclusion constitutes a more useful strategy. If this model is accurate, then human social exclusion should be utilized by females more than males and females should be more sensitive to its occurrence. Here we present four studies supporting this model. In Study 1, using a computerized game with fictitious opponents, we demonstrate that females are more willing than males to socially exclude a temporary ally. In Study 2, females report more actual incidents of social exclusion than males do. In Study 3, females perceive cues revealing social exclusion more rapidly than males do. Finally, in Study 4, females’ heart rate increases more than males’ in response to social exclusion. Together, results indicate that social exclusion is a strategy well-tailored to human females’ social structure.Human Evolutionary Biolog
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