Children and the Welfare State: The Need for a Child-Centered Analysis

Variation in child well-being across rich Western nations suggests that the welfare state may play a role in shaping child well-being. However, welfare scholars have largely overlooked children in their analyses. This paper seeks to bring children to the center of welfare state analysis by examining how comparative welfare state theory can consider child well-being. The paper begins with an examination of Esping- Andersen’s seminal work, The Three Worlds of Welfare Capitalism, which has come to frame welfare state analysis for nearly three decades. Next, the paper explores the main critiques of Esping-Andersen’s work, with special attention paid to the feminist critique and the construction of alternative feminist and family policy regimes. Finally, this paper extends and reworks Esping-Andersen’s Three Worlds to offer a new framework for conducting child-centered welfare state analyses

Marginalizing Mothers: Child Maltreatment Registries, Statutory Schemes, and Reduced Opportunities for Employment

State child welfare systems substantiate over 500,000 allegations of child maltreatment each year and hold parents responsible for this maltreatment in most cases. Parents who are substantiated are often listed on state child maltreatment registries for years, if not decades. Originally designed to investigate and process allegations of child mal-treatment, registries and the data they contain are increasingly used by employers to identify perpetrators of maltreatment and essentially bar them from employment in occupations that care for children and other vulnerable populations. As a consequence of this use, thousands of parents are prevented from engaging in paid care work, undermining their ability to care for themselves and their families. Through a review of state statutory schemes, child welfare data, and policy and practice documents, this article documents, compares, and assesses the strengths and limitations of existing statutory schemes; highlights the due process challenges they raise; considers their disproportionate im-pact on poor women, many of whom are Black; and suggests statutory reforms that work to safeguard children while minimizing economic consequences to familie

Child Protective Service Referrals Involving Exposure to Domestic Violence: Prevalence, Associated Maltreatment Types, and Likelihood of Formal Case Openings

Childhood exposure to domestic violence (CEDV) is widely understood as potentially harmful to children. Accordingly, many child welfare systems in the United States construe CEDV as maltreatment when the exposure results in harm or threatened harm to the child. The purpose of the current study was to investigate substantiated child welfare referrals directly related to CEDV to better understand the prevalence and patterns of CEDV-related maltreatment and how child welfare workers respond under the “harm or threatened harm” standard. Data were drawn from 23,704 substantiated referrals between 2009 and 2013 in a large Midwestern child welfare system. Approximately 20% of substantiated referrals were CEDV related. A plurality of CEDV-related referrals included both a male caregiver and female caregiver who were co-substantiated for maltreatment. The most common maltreatment types substantiated for these referrals were neglect based rather than abuse based, and just under a quarter (23%) of CEDV-related referrals were formally opened for services. Referrals involving co-occurring substance abuse were most likely to be opened for services based on predicted probabilities derived from multilevel modeling. Implications for policy and practice are considered

Leucaena establishment on frontage country in the Queensland Gulf

Introduction and successful establishment of leucaena (Leucaena leucocephala) has the potential to improve annual liveweight gains (LWGs) of grazing cattle in northern Australia, sustainably increase gross margins and mitigate methane production (Harrison et al. 2015). However, leucaena adoption in northern Queensland to date has been low (<2,500 ha established) compared with other regions of the State

A Pilot Double-Blind Randomized Controlled Trial of Cognitive Training Combined with Transcranial Direct Current Stimulation for Amnestic Mild Cognitive Impairment

Background: There is currently no effective intervention for improving memory in people at increased risk for dementia. Cognitive training (CT) has been promising, though effects are modest, particularly at follow-up. Objective: To investigate whether adjunctive non-invasive brain stimulation (transcranial direct current stimulation, tDCS) could enhance the memory benefits of CT in amnestic mild cognitive impairment (aMCI). Methods: Participants with aMCI were randomized to receive CT with either Active tDCS (2mA for 30min and 0.016mA for 30min) or Sham tDCS (0.016mA for 60min) for 15 sessions over a period of 5 weeks in a double-blind, sham-controlled, parallel group clinical trial. The primary outcome measure was the California Verbal Learning Task 2nd Edition. Results: 68 participants commenced the intervention. Intention-to-treat (ITT) analysis showed that the CT+Active tDCS group significantly improved at post treatment (p=0.033), and the CT+Sham tDCS group did not (p=0.050), but there was no difference between groups. At the 3-month follow-up, both groups showed large-sized memory improvements compared to pre-treatment (CT+Active tDCS: p<0.01, d=0.99; CT+Sham tDCS: p<0.01, d=0.74), although there was no significant difference between groups. Conclusion: This study found that CT+Active tDCS did not produce greater memory improvement compared to CT+Sham tDCS. Large-sized memory improvements occurred in both conditions at follow-up. One possible interpretation, based on recent novel findings, is that low intensity tDCS (used as 'sham') may have contributed biological effects. Further work should use a completely inert tDCS sham condition

The History, Development, and Purpose of the Sensory Integration Global Network

The Sensory Integration Global Network (SIGN) is a Web-based resource developed by a loosely structured group of international volunteers dedicated to protecting the integrity and promoting the work of Ayres Sensory Integration® (ASI). SIGN provides an international resource to educate the public and professionals about A. Jean Ayres and sensory integration theory and practice to help them to discriminate between ASI and other interventions, especially those that use similar descriptors of improving sensory integration and sensory processing. This article aims to increase awareness of the existence of SIGN within the readership of the American Occupational Therapy Association\u27s (AOTA\u27 s) Sensory Integration Special Interest Section. The persons working with SIGN hope that by informing the public about the trademark and exposing both the public and professionals to the underlying principles incorporated within the trademarked ASI approach, consumers will be able to make educated choices about the types of interventions they access. Additionally, the network hopes to assist practitioners by clarifying the terminology used when describing sensory integration practice

A computational model of induced pluripotent stem-cell derived cardiomyocytes incorporating experimental variability from multiple data sources

KEY POINTS: Induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) capture patient-specific genotype-phenotype relationships, as well as cell-to-cell variability of cardiac electrical activity Computational modelling and simulation provide a high throughput approach to reconcile multiple datasets describing physiological variability, and also identify vulnerable parameter regimes We have developed a whole-cell model of iPSC-CMs, composed of single exponential voltage-dependent gating variable rate constants, parameterized to fit experimental iPSC-CM outputs We have utilized experimental data across multiple laboratories to model experimental variability and investigate subcellular phenotypic mechanisms in iPSC-CMs This framework links molecular mechanisms to cellular-level outputs by revealing unique subsets of model parameters linked to known iPSC-CM phenotypes ABSTRACT: There is a profound need to develop a strategy for predicting patient-to-patient vulnerability in the emergence of cardiac arrhythmia. A promising in vitro method to address patient-specific proclivity to cardiac disease utilizes induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs). A major strength of this approach is that iPSC-CMs contain donor genetic information and therefore capture patient-specific genotype-phenotype relationships. A cited detriment of iPSC-CMs is the cell-to-cell variability observed in electrical activity. We postulated, however, that cell-to-cell variability may constitute a strength when appropriately utilized in a computational framework to build cell populations that can be employed to identify phenotypic mechanisms and pinpoint key sensitive parameters. Thus, we have exploited variation in experimental data across multiple laboratories to develop a computational framework for investigating subcellular phenotypic mechanisms. We have developed a whole-cell model of iPSC-CMs composed of simple model components comprising ion channel models with single exponential voltage-dependent gating variable rate constants, parameterized to fit experimental iPSC-CM data for all major ionic currents. By optimizing ionic current model parameters to multiple experimental datasets, we incorporate experimentally-observed variability in the ionic currents. The resulting population of cellular models predicts robust inter-subject variability in iPSC-CMs. This approach links molecular mechanisms to known cellular-level iPSC-CM phenotypes, as shown by comparing immature and mature subpopulations of models to analyse the contributing factors underlying each phenotype. In the future, the presented models can be readily expanded to include genetic mutations and pharmacological interventions for studying the mechanisms of rare events, such as arrhythmia triggers.S