41 research outputs found

    The epitaxy of gold

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    N=151Pu, Cm and Cf nuclei under rotational stress: Role of higher-order deformations

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    Fast-rotating N=151 isotones 245Pu, 247Cm and 249Cf have been studied through inelastic excitation and transfer reactions with radioactive targets. While all have a ground-state band built on a νj15/2[734]9/2- Nilsson configuration, new excited bands have also been observed in each isotone. These odd-N excited bands allow a comparison of the alignment behavior for two different configurations, where the νj15/2 alignment is either blocked or allowed. The effect of higher order deformations is explored through cranking calculations, which help clarify the elusive nature of νj15/2 alignments

    Variation in Structure and Process of Care in Traumatic Brain Injury: Provider Profiles of European Neurotrauma Centers Participating in the CENTER-TBI Study.

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    INTRODUCTION: The strength of evidence underpinning care and treatment recommendations in traumatic brain injury (TBI) is low. Comparative effectiveness research (CER) has been proposed as a framework to provide evidence for optimal care for TBI patients. The first step in CER is to map the existing variation. The aim of current study is to quantify variation in general structural and process characteristics among centers participating in the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) study. METHODS: We designed a set of 11 provider profiling questionnaires with 321 questions about various aspects of TBI care, chosen based on literature and expert opinion. After pilot testing, questionnaires were disseminated to 71 centers from 20 countries participating in the CENTER-TBI study. Reliability of questionnaires was estimated by calculating a concordance rate among 5% duplicate questions. RESULTS: All 71 centers completed the questionnaires. Median concordance rate among duplicate questions was 0.85. The majority of centers were academic hospitals (n = 65, 92%), designated as a level I trauma center (n = 48, 68%) and situated in an urban location (n = 70, 99%). The availability of facilities for neuro-trauma care varied across centers; e.g. 40 (57%) had a dedicated neuro-intensive care unit (ICU), 36 (51%) had an in-hospital rehabilitation unit and the organization of the ICU was closed in 64% (n = 45) of the centers. In addition, we found wide variation in processes of care, such as the ICU admission policy and intracranial pressure monitoring policy among centers. CONCLUSION: Even among high-volume, specialized neurotrauma centers there is substantial variation in structures and processes of TBI care. This variation provides an opportunity to study effectiveness of specific aspects of TBI care and to identify best practices with CER approaches

    First results of a coated heat exchanger for the use in dehumidification and cooling processes

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    In this work a novel solar driven dehumidification and cooling system is presented. The core components of this combined system are a sorptive dehumidification device based on high performance sorptive coatings and a novel evacuated tube solar air collector providing the driving heat. The essential part of the system is the coated heat exchanger. The chosen adsorbent is attached to the heat exchanger surface by a newly developed coating technique. Besides a brief description of the novel components and the experimental setup, the development of the aluminum heat exchanger, the coating procedure and scale up for geometries comparable to the heat exchanger in the dehumidification setup, as well as a first characterization of a small-sized coated heat exchanger regarding water uptake and dehumidification performance are presented. For estimating an overall system performance, a 2-dimensional thermodynamic model was applied, using the parameters in focus for the development of heat exchanger, coating and demonstration system

    Genes and gene clusters related to genotype and drought-induced variation in saccharification potential, lignin content and wood anatomical traits in Populus nigra

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    Wood is a renewable resource that can be employed for the production of second generation biofuels by enzymatic saccharification and subsequent fermentation. Knowledge on how the saccharification potential is affected by genotype-related variation of wood traits and drought is scarce. Here, we used three Populus nigra L. genotypes from habitats differing in water availability to (i) investigate the relationships between wood anatomy, lignin content and saccharification and (ii) identify genes and co-expressed gene clusters related to genotype and drought-induced variation in wood traits and saccharification potential. The three poplar genotypes differed in wood anatomy, lignin content and saccharification potential. Drought resulted in reduced cambial activity, decreased vessel and fiber lumina, and increased the saccharification potential. The saccharification potential was unrelated to lignin content as well as to most wood anatomical traits. RNA sequencing of the developing xylem revealed that 1.5% of the analyzed genes were differentially expressed in response to drought, while 67% differed among the genotypes. Weighted gene correlation network analysis identified modules of co-expressed genes correlated with saccharification potential. These modules were enriched in gene ontology terms related to cell wall polysaccharide biosynthesis and modification and vesicle transport, but not to lignin biosynthesis. Among the most strongly saccharification-correlated genes, those with regulatory functions, especially kinases, were prominent. We further identified transcription factors whose transcript abundances differed among genotypes, and which were co-regulated with genes for biosynthesis and modifications of hemicelluloses and pectin. Overall, our study suggests that the regulation of pectin and hemicellulose metabolism is a promising target for improving wood quality of second generation bioenergy crops. The causal relationship of the identified genes and pathways with saccharification potential needs to be validated in further experiments
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