Kritik Otoritas Pemaknaan Hadis Menuju Masyarakat Islam Berkemajuan

Sepeninggal Rasulullah Saw. perdebatan seputar keabsahan hadis sebagai sumber hukum Islam tampaknya tidak akan menemukan akhir. Bahkan, kecenderungan dalam hal ini mengarah kepada semakin tingginya intensitas perdebatan seputar keabsahan dan keotentikan hadis. Ini tidak hanya terjadi di kalangan ulama hadis yang muslim, tetapi juga di kalangan orientalis Barat non muslim yang menaruh perhatian kepada studi hadis

Analisis Pengaruh Variasi Tekanan Pada Pengecoran Squeeze Terhadap Struktur Mikro Dan Kekerasan Produk Sepatu Kampas Rem Berbahan Aluminium Silikon (Al-si) Daur Ulang Dengan Penambahan 0,05% Unsur Titanium (Ti)

Pengecoran squeeze atau yang sering juga disebut penempaan logam cair adalah proses dimana logam cair dibiarkan membeku dalam cetakan yang diberi tekanan ekternal. Penelitian ini bertujuan untuk mengetahuipengaruh tekanan terhadap struktur mikrodan kekerasan pada proses pembuatan kampas rem dengan penambahan titanium (Ti) paduan aluminium daur ulang. Paduan dilebur pada dapur peleburan dan dituang pada temperatur 700 kedalam cetakan yang telah dipanaskan pada temperatur 300 selanjutnya diberi tekanan dengan variasi tanpa tekanan, tekanan 104MPa, 149Mpa dan 194MPa selama 8 menit. Hasil penelitian menunjukkan bahwa semakin tinggi tekanan yang diberikan porositasnya semakin sedikit, SDAS semakin kecil, dan nilai kekerasan naik. Katakunci: Pengecoran squeeze, daur ulang, tekanan

Kontribusi Pendapatan Agroindustri Gula Kelapa terhadap Pendapatan Total Keluarga Perajin

Tujuan penelitian ini adalah untuk mengetahui 1) Besarnya pendapatan agroindustri gula kelapa per bulan di Desa Sukanagara Kecamatan Lakbok Kabupaten Ciamis, 2) Besarnya pendapatan total keluarga perajin USAha gula kelapa per bulan di Desa Sukanagara Kecamatan Lakbok Kabupaten Ciamis, 3) Besarnya kontribusi pendapatan agroindustri gula kelapa per bulan terhadap pendapatan total keluarga perajin di Desa Sukanagara Kecamatan Lakbok Kabupaten Ciamis. Metode yang digunakan dalam penelitian ini analisis deskriptif dengan teknik survey. Sedangkan untuk menganalisis data yang diperoleh digunakan Analisis ekonomi yang meliputi analisa biaya, penerimaan, pendapatan dan kontribusi pendapatan USAha gula kelapa. Hasil dari penelitian dan pengolahan data menunjukan bahwa 1) Jumlah rata-rata pendapatan agroindustri gula kelapa di Desa Sukanagara Kecamatan Lakbok Kabupaten Ciamis sebesar Rp 1.406.669,29 per bulan. 2) Jumlah rata-rata pendapatan total keluarga perajin di Desa Sukanagara Kecamatan Lakbok Kabupaten Ciamis sebesar Rp 1.902.663,61 per bulan. 3) Kontribusi pendapatan dari USAha gulakelapa terhadap pendapatan total keluarga perajin responden rata-rata sebesar 73,93% per bulan. Diharapkan Agroindustri gula kelapa dipertahankan bahkan ditingkatkan dengan cara penambahan modal sehingga diperoleh pendapatan yang lebih besar

A protocol for primary isolation and culture of adipose-derived stem cells and their phenotypic profile

Background: Adipose tissue (AT) is a rich source of mesenchymal stem cells (MSCs), however, there is no standardized protocol for stem cell isolation and culture. This leads to inconsistency of the results and limits the comparison of the data from different laboratories. Our aim was to provide an applied protocol for ASCS isolation and expansion, study the cell behavior and define their cellular surface markers. ASCs were cultured from both resected adipose tissue (RAT) obtained following abdominoplasty or breast reduction and lipoaspirates (LPA) following laser-free liposuction. Method: the protocol entailed coculturing of stromal vascular fraction (SVF) with RAT as raw pieces using DMEM medium with varying glucose concentration. The coculture protocol aimed to mimic the normal physiological conditions required for cell growth. ASCs were immunophenotyped to define their MSCs surface markers by flowcytometry. Results: ASCs were isolated from coculturing RAT with SVF with fibroblast-like adherent cells morphology. The ASCs yield isolated from LPA was significantly greater than from RAT on day 14 and 28 (p = 0.002, <0.001, respectively). Significant increase in ASCs proliferation rate was detected when ASCs were cultured under high glucose (4.5 g/L) compared to low glucose (1 g/ L) condition on day 7 and 14 (p = 0.04, 0.015, respectively). ASCs isolated from both protocols were positive for CD34, CD49d, CD73, CD90 and CD105 and negative for CD3, CD14, CD19, CD45 and HLA-DR. Conclusion: We concluded that the cells harvested by our protocol were ASCs. Hence, our method can be an efficient isolation tool to obtain primary ASCs under culture conditions mimicking normal physiological status. This will help in providing ASCs which can be similar to cells in human tissue for further study

An Integrated ERP with Web Portal

Abstract Making the right decision at the right time requires that the data should be available at internet time not after the event when it is too late to do anything. So the need for a web portal has been increased in order to support decision making in the different organizational levels at internet time by providing features such as, customization, personalization, support for collaboration and notification that support managers in making the right decision at internet time. All this can be achieved by applying the (BI) tools on " One version" data store that contains data from legacy ERP system after applying the ETL tools over it. Also the Data marts will be used in order to shorten the response time of queries generated by the users

Strontium and Oxygen Isotope Analyses Reveal Late Cretaceous Shark Teeth in Iron Age Strata in the Southern Levant

Skeletal remains in archaeological strata are often assumed to be of similar ages. Here we show that combined Sr and O isotope analyses can serve as a powerful tool for assessing fish provenance and even for identifying fossil fish teeth in archaeological contexts. For this purpose, we established a reference Sr and O isotope dataset of extant fish teeth from major water bodies in the Southern Levant. Fossil shark teeth were identified within Iron Age cultural layers dating to 8–9th century BCE in the City of David, Jerusalem, although the reason for their presence remains unclear. Their enameloid 87Sr/86Sr and δ18OPO4 values [0.7075 ± 0.0001 (1 SD, n = 7) and 19.6 ± 0.9‰ (1 SD, n = 6), respectively], are both much lower than values typical for modern marine sharks from the Mediterranean Sea [0.7092 and 22.5–24.6‰ (n = 2), respectively]. The sharks’ 87Sr/86Sr are also lower than those of rain- and groundwater as well as the main soil types in central Israel (≥0.7079). This indicates that these fossil sharks incorporated Sr (87Sr/86Sr ≈ 0.7075) from a marine habitat with values typical for Late Cretaceous seawater. This scenario is in line with the low shark enameloid δ18OPO4 values reflecting tooth formation in the warm tropical seawater of the Tethys Ocean. Age estimates using 87Sr/86Sr stratigraphy place these fossil shark teeth at around 80-million-years-old. This was further supported by their taxonomy and the high dentine apatite crystallinity, low organic carbon, high U and Nd contents, characteristics that are typical for fossil specimens, and different from those of archaeological Gilthead seabream (Sparus aurata) teeth from the same cultural layers and another Chalcolithic site (Gilat). Chalcolithic and Iron Age seabream enameloid has seawater-like 87Sr/86Sr of 0.7091 ± 0.0001 (1 SD, n = 6), as expected for modern marine fish. Fossil shark and archaeological Gilthead seabream teeth both preserve original, distinct enameloid 87Sr/86Sr and δ18OPO4 signatures reflecting their different aquatic habitats. Fifty percent of the analysed Gilthead seabream teeth derive from hypersaline seawater, indicating that these seabreams were exported from the hypersaline Bardawil Lagoon in Sinai (Egypt) to the Southern Levant since the Iron Age period and possibly even earlier

Validity of the Shahin Mixed Depression Scale: A Self-Rated Instrument Designed to Measure the Non-DSM Mixed Features in Depression

Background: The DSM5-defined mixed features in depression do not include psychomotor agitation, irritability or distractibility because they are considered overlapping symptoms. A growing number of modern psychiatrists have expressed dissatisfaction with this and proposed alternative sets of mixed symptoms that are much more common and clinically relevant. Among such alternative criteria were those proposed by Koukopoulos. He utilized the research diagnostic criteria of agitated depression (RDC-A) as a mixed depression subtype, and validated another form of mixed depression, the Koukopoulos criteria for mixed depression (K-DMX). Purpose: This study provides psychometric validation for the first self-rated scale designed to measure the most common mixed symptoms in depression as proposed by Koukopoulos. Patients and methods: We conducted a multicenter cross-sectional study of 170 patients with unipolar depression. They completed the Shahin Mixed Depression Scale (SMDS) and underwent expert interviews as a gold standard reference. SMDS' psychometric properties were assessed, including Cronbach's alpha, factor analysis, sensitivity, specificity, predictive value and accuracy. Results: We found significant association and agreement between mixity according to SMDS and the gold standard (K-DMX and RDC-A according to expert interview) with good internal consistency (Cronbach's alpha=0.87), high sensitivity (=91.4%), specificity (=98.0%), positive predictive value (=96.9%), negative predictive value (= 94.2%) and accuracy (=95.2%). Factor analysis identified one factor for psychomotor agitation and another for mixity without psychomotor agitation. Conclusion: SMDS was a reliable and valid instrument for assessing the frequently encountered and clinically relevant mixed features in depression

PERPADUAN MODEL PEMBELAJARAN INKUIRI DENGAN POE (Predict-Observe-Explain) DALAM MENINGKATKAN HASIL BELAJAR SISWA SMP NEGERI 1 KAIRATUBackground: Learning outcomes are changes in student behavior due to learning. Behavior change is caused by achieving mast

Background: Learning outcomes are changes in student behavior due to learning. Behavior change is caused by achieving mastery over a number of materials given in the teaching and learning process. These results can be in the form of changes in cognitive, affective and psychomotor aspects. This study aims to determine the increase in student learning outcomes of SMP Negeri 1 Kairatu on the excretion system in humans which is taught by applying the inquiry learning model combined with the POE (Predict-Observe-Explain) learning model. Method: The data obtained were analyzed descriptively. In this study, tests were given at the beginning and end of learning aimed to determine the level of student understanding of the material excretory system in humans. Non-test techniques in the form of affective assessment sheets and psychomotor assessment sheets. Results: Students' understanding of material in the Excretion System in humans prior to the implementation of the inquiry learning model combined with the POE (Predict-Observe-Explain) learning model is very low but, when integrating these two learning models there are many changes in student understanding that can be seen from their learning outcomes. Conclusion: There is an increase in student learning outcomes after conducting the teaching and learning process by using the inquiry learning model that is integrated with the POE (Predict-Observe- Explain) learning model on excretory material in human

Liver resection rate following downsizing chemotherapy with cetuximab in metastatic colorectal cancer: UK retrospective observational study

Aims The high objective response rate to cetuximab along with chemotherapy in patients with colorectal liver metastases makes it an effective downsizing protocol to facilitate surgery in those with initially unresectable disease. Adoption of this strategy has been variable in the UK. A retrospective observational study was conducted in 7 UK specialist liver surgical centres to describe the liver resection rate following a downsizing protocol of cetuximab and chemotherapy and to evaluate the quality and efficiency of processes by which the treatment was provided. Methods Data were collected in 2012 by reviewing medical records of patients with colorectal metastases confined to the liver, defined as unresectable without downsizing therapy at first review by a specialist Multi Disciplinary Team (MDT). Results Sixty patients were included; 29 (48%) underwent liver resection following cetuximab and chemotherapy. Of the 29, 17 (59% or 28% of all patients) achieved R0 resection and 7 (24% or 12% of all patients) R1 resection. All treated patients were KRAS wild-type. Conclusion In specialist liver surgical centres, where patients are evaluated for liver resection, optimal management by MDT using KRAS testing, cetuximab and chemotherapy results in a 28% R0 resection rate in patients with initially unresectable colorectal cancer liver metastases

The potential use of service-oriented infrastructure framework to enable transparent vertical scalability of cloud computing infrastructure

Cloud computing technology has become familiar to most Internet users. Subsequently, there has been an increased growth in the use of cloud computing, including Infrastructure as a Service (IaaS). To ensure that IaaS can easily meet the growing demand, IaaS providers usually increase the capacity of their facilities in a vertical IaaS increase capability and the capacity for local IaaS amenities such as increasing the number of servers, storage and network bandwidth. However, at the same time, horizontal scalability is sometimes not enough and requires additional strategies to ensure that the large number of IaaS service requests can be met. Therefore, strategies requiring horizontal scalability are more complex than the vertical scalability strategies because they involve the interaction of more than one facility at different service centers. To reduce the complexity of the implementation of the horizontal scalability of the IaaS infrastructures, the use of a technology service oriented infrastructure is recommended to ensure that the interaction between two or more different service centers can be done more simply and easily even though it is likely to involve a wide range of communication technologies and different cloud computing management. This is because the service oriented infrastructure acts as a middle man that translates and processes interactions and protocols of different cloud computing infrastructures without the modification of the complex to ensure horizontal scalability can be run easily and smoothly. This paper presents the potential of using a service-oriented infrastructure framework to enable transparent vertical scalability of cloud computing infrastructures by adapting three projects in this research: SLA@SOI consortium, Open Cloud Computing Interface (OCCI), and OpenStack