Barriers to the Employment of Welfare Recipients

Dramatic reductions in welfare caseloads since passage of the Personal Responsibility and WorkOpportunity Reconciliation Act of 1996 have not allayed policy concerns about the employability of recipients remaining on the rolls. Analysis of potential barriers to employment can address whether current recipients have problems that either singly or in combination make it difficult for them to comply with the new requirements for getting and keeping jobs. In this paper, we explore the prevalence and work effects of 14 potential barriers in a new survey of a representative sample of 753 urban single-mother recipients. We report the prevalence of the barriers and how their number predicts employment rates, controlling for demographic characteristics. We also analyze which individual barriers are associated with employment and how a model inclusive of a comprehensive array of barriers improves upon a traditional human capital model of the work effects of education and work and welfare history. Single mothers who received welfare in 1997 had higher rates of personal health and mental health problems, domestic violence, and children’s health problems than do women in national samples, but they were no more likely than the general population to be drug or alcohol dependent. Only 15 percent of respondents had none of the barriers and almost two-thirds had two or more barriers. The numbers of multiple barriers were strongly and negatively associated with working, and among the individual barriers, low education, lack of access to transportation, poor health, having drug dependence or a major depressive disorder, and several experiences of workplace discrimination reduced employment. Welfare-to-work programs need to be more finely targeted with respect to exemptions and service provision, and states should consider providing longer-term and enhanced supports for those who face low prospects of leaving welfare for employment.

JPL IGS Analysis Center Report, 2001-2003

Three GPS orbit and clock products are currently provided by JPL for consideration by the IGS. Each differs in its latency and quality, with later results being more accurate. Results are typically available in both IGS and GIPSY formats via anonymous ftp. Current performance based on comparisons with the IGS final products is summarized. Orbit performance was determined by computing the 3D RMS difference between each JPL product and the IGS final orbits based on 15 minute estimates from the sp3 files. Clock performance was computed as the RMS difference after subtracting a linear trend based on 15 minute estimates from the sp3 files

Local coherence and the temporal development of second harmonic emission

In a variety of mesoscopically disordered systems, high levels of optical excitation resulting from pulsed laser irradiation can establish optical coherence within separate particles or locally ordered domains, leading to second harmonic emission whose temporal signature characterizes the decay of the excited state population. Examples of such systems will include colloids, cell and membrane suspensions, and many plastics, glasses and other modern materials. With pulsed excitation of sufficient intensity to elicit the onset of saturation, second harmonic emission on the throughput of a subsequent probe beam exhibits a characteristic decay and recovery. Detailed calculations show that such features arise not only in systems whose optical response involves two discrete levels, but also in systems of considerably greater electronic complexity. Deconvolution of the temporal trace of the harmonic signal serves as an independent means of monitoring the decay of the excited state. The extent of recovery in the harmonic signal also serves to register the extent of local coherence, and hence in many systems the localization of structural order. Finally, the principles introduced in the theory are shown to be applicable to other types of system such as certain photochromic materials

2016+112: A Gravitationally Lensed Type-II Quasar

A single-screen model of the gravitational lens system 2016+112 is proposed, that explains recent Hubble Space Telescope} (HST) infrared (NICMOS-F160W) observations and new high-resolution European VLBI Network (EVN) 5-GHz radio observations, presented in this paper. In particular, we find that a massive `dark' structure at the lens position, previously suggested by X-ray, optical and spectroscopic observations of the field around 2016+112, is not necessarily required to accommodate the strong lensing constraints. A massive structure to the north-west of the lens system, suggested from a weak-lensing analysis of the field, is included in the model. The lensed source is an X-ray bright active galaxy at z=3.273 with a central bright optical continuum core and strong narrow emission lines, suggestive of a type-II quasar. The EVN 5-GHz radio maps show a radio-jet structure with at least two compact subcomponents. We propose that the diamond caustic crosses the counter-jet of the radio source, so that part of the counter-jet, host galaxy and narrow-line emission regions are quadruply imaged. The remainder of the radio source, including the core, is doubly imaged. Our lens model predicts a very high magnification (mu~300) at the bightness peaks of the inner two radio components of complex C. If the jet exhibits relativistic velocities on micro-arsecond scales, it might result in apparent hyperluminal motion. However, the lack of strong radio variability and the peaked radio spectrum imply that these motions need not be present in the source. Our model furthermore implies that the optical spectrum of C' can only show features of the AGN and its host galaxy.Comment: 10 pages, 3 figures, accepted by MNRAS; minor change

Radio Astronomy

Contains table of contents and reports on seven research projects.National Science Foundation (Grant AST 86-17172)National Aeronautics and Space AdministrationJet Propulsion LaboratoryNASA/Goddard Space Flight Center (Grant NAG5-10)SM Systems and Research, Inc.U.S. Navy Office of Naval Research (Contract N00014-86-C-2114)Center for Advanced Television StudiesNASA/Goddard Space Flight Center (Grant NAG5-537

Berberine modulates expression of mdr1 gene product and the responses of digestive track cancer cells to Paclitaxel

Berberine is the major constituent of Coptis chinese and is commonly used in Chinese herbal medicine to treat patients with gastrointestinal disorders. In this study, using flow cytometry, we have found that a 24-h berberine treatment up-regulated the multidrug-resistant transporter (pgp-170) expression in two oral (KB, OC2), two gastric (SC-M1, NUGC-3) and two colon (COLO 205, CT 26) cancer cell lines. Decreased retention of rhodamine 123 was observed in berberine-treated cells as compared to vehicle control. To examine whether the berberine modulated pgp-170 expression in cancer cells is associated with changes in drug resistance, we determined the cytotoxicity, cell cycle progression and cell morphology of Paclitaxel-treated cells. Paclitaxel (1 nM–10 μM) treatment for 24 h induced cytotoxicity in OC2, SC-M1 and COLO 205 cells in a dose-dependent manner. Pretreatment of cells with 32 μM berberine for 24 h prior to Paclitaxel treatment resulted in increased viability as compared to that of Paclitaxel-treated cells. In addition, Paclitaxel-induced apoptosis and/or G2/M arrest in these three cancer cell lines. Pretreatment of cells with berberine prior to Paclitaxel blocked the Paclitaxel-induced cell cycle responses and morphological changes. These results together suggest that berberine modulated the expression and function of pgp-170 that leads to reduced response to Paclitaxel in digestive track cancer cells. © 1999 Cancer Research Campaig

Radio Astronomy

Contains reports on nine research projects.National Science Foundation (Grant AST 86-17172)National Aeronautics and Space Administration (Contract NAS7-918)Jet Propulsion Laboratory (Contract 958048)U.S. Navy - Office of Naval Research (Contract N00014-84-C-2082)U.S. Navy - Office of Naval Research (Contract N00014-86-C-2114)SM Systems and Research, Inc.National Aeronautics and Space Administration/Goddard Space Flight Center (Grant NAG5-10)Center for Advanced Television StudiesBrazil, Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (Grant 300.832-82)National Aeronautics and Space Administration/Goddard Space Flight Center (Grant NAG5-537