717 research outputs found
Visual pigments and oil droplets from six classes of photoreceptor in the retinas of birds
AbstractMicrospectrophotometric examination of the retinal photoreceptors of the budgerigar (shell parakeet), Melopsittacus undulatus (Psittaciformes) and the zebra finch, Taeniopygia guttata (Passeriformes), demonstrate the presence of four, spectrally distinct classes of single cone that contain visual pigments absorbing maximally at about 565, 507, 430–445 and 360–380 nm. The three longer-wave cone classes contain coloured oil droplets acting as long pass filters with cut-offs at about 570, 500–520 and 445 nm, respectively, whereas the ultraviolet-sensitive cones contain a transparent droplet. The two species possess double cones in which both members contain the long-wave-sensitive visual pigment, but only the principal member contains an oil droplet, with cut-off at about 420 nm. A survey of the cones of the pigeon, Columba livia (Columbiformes), confirms the presence of the three longer-wave classes of single cone, but also reveals the presence of a fourth class containing a visual pigment with maximum absorbance at about 409 nm, combined with a transparent droplet. No evidence was found for a fifth, ultraviolet-sensitive receptor. In the chicken, Gallus gallus (Galliformes), the cone class with a transparent droplet contains “chicken violet” with maximum absorbance at about 418 nm. The rods of all four species contain visual pigments that are spectrally similar, with maximum absorbance between about 506 and 509 nm. Noticeably, in any given species, the maximum absorbance of the rods is spectrally very similar the maximum absorbance of the middle-wavelength-sensitive cone pigments
A jump-growth model for predator-prey dynamics: derivation and application to marine ecosystems
This paper investigates the dynamics of biomass in a marine ecosystem. A
stochastic process is defined in which organisms undergo jumps in body size as
they catch and eat smaller organisms. Using a systematic expansion of the
master equation, we derive a deterministic equation for the macroscopic
dynamics, which we call the deterministic jump-growth equation, and a linear
Fokker-Planck equation for the stochastic fluctuations. The McKendrick--von
Foerster equation, used in previous studies, is shown to be a first-order
approximation, appropriate in equilibrium systems where predators are much
larger than their prey. The model has a power-law steady state consistent with
the approximate constancy of mass density in logarithmic intervals of body mass
often observed in marine ecosystems. The behaviours of the stochastic process,
the deterministic jump-growth equation and the McKendrick--von Foerster
equation are compared using numerical methods. The numerical analysis shows two
classes of attractors: steady states and travelling waves.Comment: 27 pages, 4 figures. Final version as published. Only minor change
Habitable Zones and UV Habitable Zones around Host Stars
Ultraviolet radiation is a double-edged sword to life. If it is too strong,
the terrestrial biological systems will be damaged. And if it is too weak, the
synthesis of many biochemical compounds can not go along. We try to obtain the
continuous ultraviolet habitable zones, and compare the ultraviolet habitable
zones with the habitable zones of host stars. Using the boundary ultraviolet
radiation of ultraviolet habitable zone, we calculate the ultraviolet habitable
zones of host stars with masses from 0.08 to 4.00 \mo. For the host stars with
effective temperatures lower than 4,600 K, the ultraviolet habitable zones are
closer than the habitable zones. For the host stars with effective temperatures
higher than 7,137 K, the ultraviolet habitable zones are farther than the
habitable zones. For hot subdwarf as a host star, the distance of the
ultraviolet habitable zone is about ten times more than that of the habitable
zone, which is not suitable for life existence.Comment: 5 pages, 3 figure
Metal enrichment processes
There are many processes that can transport gas from the galaxies to their
environment and enrich the environment in this way with metals. These metal
enrichment processes have a large influence on the evolution of both the
galaxies and their environment. Various processes can contribute to the gas
transfer: ram-pressure stripping, galactic winds, AGN outflows, galaxy-galaxy
interactions and others. We review their observational evidence, corresponding
simulations, their efficiencies, and their time scales as far as they are known
to date. It seems that all processes can contribute to the enrichment. There is
not a single process that always dominates the enrichment, because the
efficiencies of the processes vary strongly with galaxy and environmental
properties.Comment: 18 pages, 8 figures, accepted for publication in Space Science
Reviews, special issue "Clusters of galaxies: beyond the thermal view",
Editor J.S. Kaastra, Chapter 17; work done by an international team at the
International Space Science Institute (ISSI), Bern, organised by J.S.
Kaastra, A.M. Bykov, S. Schindler & J.A.M. Bleeke
Is the writing on the wall for tabletops?
We describe an ethnographic study that explores how low tech and new tech surfaces support participation and collaboration during a workshop breakout session. The low tech surfaces were post-it notes and large sheets of paper. The new tech surfaces were writeable walls and a multi-touch tabletop. Four groups used the different surfaces during three phases: i) brief presentation of position papers and discussion of themes, ii) the creation of a group presentation and iii) a report back session. Participation and collaboration varied depending on the physical, technological and social factors at play when using the different surfaces. We discuss why this is the case, noting how new shareable surfaces may need to be constrained to invite participation in ways that are simply taken for granted because of their familiarity when using low tech materials
Quantifying Between-Cohort and Between-Sex Genetic Heterogeneity in Major Depressive Disorder
Major depressive disorder (MDD) is clinically heterogeneous with prevalence rates twice as high in women as in men. There are many possible sources of heterogeneity in MDD most of which are not measured in a sufficiently comparable way across study samples. Here, we assess genetic heterogeneity based on two fundamental measures, between-cohort and between-sex heterogeneity. First, we used genome-wide association study (GWAS) summary statistics to investigate between-cohort genetic heterogeneity using the 29 research cohorts of the Psychiatric Genomics Consortium (PGC; N cases = 16,823, N controls = 25,632) and found that some of the cohort heterogeneity can be attributed to ascertainment differences (such as recruitment of cases from hospital vs community sources). Second, we evaluated between-sex genetic heterogeneity using GWAS summary statistics from the PGC, Kaiser Permanente GERA, UK Biobank and the Danish iPSYCH studies but did not find convincing evidence for genetic differences between the sexes. We conclude that there is no evidence that the heterogeneity between MDD data sets and between sexes reflects genetic heterogeneity. Larger sample sizes with detailed phenotypic records and genomic data remain the key to overcome heterogeneity inherent in assessment of MDD
Increasing source to image distance for AP pelvis imaging – impact on radiation dose and image quality
Aim: A quantative primary study to determine whether increasing source to image distance (SID), with
and without the use of automatic exposure control (AEC) for antero-posterior (AP) pelvis imaging, reduces
dose whilst still producing an image of diagnostic quality.
Methods: Using a computed radiography (CR) system, an anthropomorphic pelvic phantom was positioned
for an AP examination using the table bucky. SID was initially set at 110 cm, with tube potential set
at a constant 75 kVp, with two outer chambers selected and a fine focal spot of 0.6 mm. SID was then
varied from 90 cm to 140 cm with two exposures made at each 5 cm interval, one using the AEC and
another with a constant 16 mAs derived from the initial exposure. Effective dose (E) and entrance surface
dose (ESD) were calculated for each acquisition. Seven experienced observers blindly graded image
quality using a 5-point Likert scale and 2 Alternative Forced Choice software. Signal-to-Noise Ratio (SNR)
was calculated for comparison. For each acquisition, femoral head diameter was also measured for
magnification indication.
Results: Results demonstrated that when increasing SID from 110 cm to 140 cm, both E and ESD reduced
by 3.7% and 17.3% respectively when using AEC and 50.13% and 41.79% respectively, when the constant
mAs was used. No significant statistical (T-test) difference (p ¼ 0.967) between image quality was
detected when increasing SID, with an intra-observer correlation of 0.77 (95% confidence level). SNR
reduced slightly for both AEC (38%) and no AEC (36%) with increasing SID.
Conclusion: For CR, increasing SID significantly reduces both E and ESD for AP pelvis imaging without
adversely affecting image quality
Observation of hard scattering in photoproduction events with a large rapidity gap at HERA
Events with a large rapidity gap and total transverse energy greater than 5
GeV have been observed in quasi-real photoproduction at HERA with the ZEUS
detector. The distribution of these events as a function of the
centre of mass energy is consistent with diffractive scattering. For total
transverse energies above 12 GeV, the hadronic final states show predominantly
a two-jet structure with each jet having a transverse energy greater than 4
GeV. For the two-jet events, little energy flow is found outside the jets. This
observation is consistent with the hard scattering of a quasi-real photon with
a colourless object in the proton.Comment: 19 pages, latex, 4 figures appended as uuencoded fil
An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics
For a decade, The Cancer Genome Atlas (TCGA) program collected clinicopathologic annotation data along with multi-platform molecular profiles of more than 11,000 human tumors across 33 different cancer types. TCGA clinical data contain key features representing the democratized nature of the data collection process. To ensure proper use of this large clinical dataset associated with genomic features, we developed a standardized dataset named the TCGA Pan-Cancer Clinical Data Resource (TCGA-CDR), which includes four major clinical outcome endpoints. In addition to detailing major challenges and statistical limitations encountered during the effort of integrating the acquired clinical data, we present a summary that includes endpoint usage recommendations for each cancer type. These TCGA-CDR findings appear to be consistent with cancer genomics studies independent of the TCGA effort and provide opportunities for investigating cancer biology using clinical correlates at an unprecedented scale. Analysis of clinicopathologic annotations for over 11,000 cancer patients in the TCGA program leads to the generation of TCGA Clinical Data Resource, which provides recommendations of clinical outcome endpoint usage for 33 cancer types
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