7,713 research outputs found
The Anisotropic Bak-Sneppen model
The Bak-Sneppen model is shown to fall into a different universality class with the introduction of a preferred direction, mirroring the situation in spin systems. This is first demonstrated by numerical simulations and subsequently confirmed by analysis of the multitrait version of the model, which admits exact solutions in the extremes of zero and maximal anisotropy. For intermediate anisotropies, we show that the spatiotemporal evolution of the avalanche has a power law `tail' which passes through the system for any non-zero anisotropy but remains fixed for the isotropic case, thus explaining the crossover in behaviour. Finally, we identify the maximally anisotropic model which is more tractable and yet more generally applicable than the isotropic system
Architecture of orogenic belts and convergent zones in Western Ishtar Terra, Venus
Linear mountain belts in Ishtar Terra were recognized from Pioneer-Venus topography, and later Arecibo images showed banded terrain interpreted to represent folds. Subsequent analyses showed that the mountains represented orogenic belts, and that each had somewhat different features and characteristics. Orogenic belts are regions of focused shortening and compressional deformation and thus provide evidence for the nature of such deformation, processes of crustal thickening (brittle, ductile), and processes of crustal loss. Such information is important in understanding the nature of convergent zones on Venus (underthrusting, imbrication, subduction), the implications for rates of crustal recycling, and the nature of environments of melting and petrogenesis. The basic elements of four convergent zones and orogenic belts in western Ishtar Terra are identified and examined, and then assess the architecture of these zones (the manner in which the elements are arrayed), and their relationships. The basic nomenclature of the convergent zones is shown
Cardiovascular disease in a cohort exposed to the 1940-45 Channel Islands occupation
BACKGROUND
To clarify the nature of the relationship between food deprivation/undernutrition during pre- and postnatal development and cardiovascular disease (CVD) in later life, this study examined the relationship between birth weight (as a marker of prenatal nutrition) and the incidence of hospital admissions for CVD from 1997–2005 amongst 873 Guernsey islanders (born in 1923–1937), 225 of whom had been exposed to food deprivation as children, adolescents or young adults (i.e. postnatal undernutrition) during the 1940–45 German occupation of the Channel Islands, and 648 of whom had left or been evacuated from the islands before the occupation began.
METHODS
Three sets of Cox regression models were used to investigate (A) the relationship between birth weight and CVD, (B) the relationship between postnatal exposure to the occupation and CVD and (C) any interaction between birth weight, postnatal exposure to the occupation and CVD. These models also tested for any interactions between birth weight and sex, and postnatal exposure to the occupation and parish of residence at birth (as a marker of parish residence during the occupation and related variation in the severity of food deprivation).
RESULTS
The first set of models (A) found no relationship between birth weight and CVD even after adjustment for potential confounders (hazard ratio (HR) per kg increase in birth weight: 1.12; 95% confidence intervals (CI): 0.70 – 1.78), and there was no significant interaction between birth weight and sex (p = 0.60). The second set of models (B) found a significant relationship between postnatal exposure to the occupation and CVD after adjustment for potential confounders (HR for exposed vs. unexposed group: 2.52; 95% CI: 1.54 – 4.13), as well as a significant interaction between postnatal exposure to the occupation and parish of residence at birth (p = 0.01), such that those born in urban parishes (where food deprivation was worst) had a greater HR for CVD than those born in rural parishes. The third model (C) found no interaction between birth weight and exposure to the occupation (p = 0.43).
CONCLUSION
These findings suggest that the levels of postnatal undernutrition experienced by children, adolescents and young adults exposed to food deprivation during the 1940–45 occupation of the Channel Islands were a more important determinant of CVD in later life than the levels of prenatal undernutrition experienced in utero prior to the occupatio
OBJECTIVE AND SOCIAL FACTORS AS DETERMINANTS OF TASK PERCEPTIONS AND RESPONSES: AN INTEGRATED PERSPECTIVE AND EMPIRICAL INVESTIGATION.
The purpose of this study was to test the merits of an integrated perspective derived from the job characteristics and social information processing models of task design. We conducted a complex laboratory study, manipulating objective properties of a task, social information, and changes in both. Results suggested strong support for the integrated perspective. Implications for future theory and research are discussed
Magellan: Preliminary description of Venus surface geologic units
Observations from approximately one-half of the Magellan nominal eight-month mission to map Venus are summarized. Preliminary compilation of initial geologic observations of the planet reveals a surface dominated by plains that are characterized by extensive and intensive volcanism and tectonic deformation. Four broad categories of units have been identified: plains units, linear belts, surficial units, and terrain units
Comparing research investment to United Kingdom institutions and published outputs for tuberculosis, HIV and malaria: A systematic analysis across 1997-2013
Background: The "Unfinished Agenda" of infectious diseases is of great importance to policymakers and research funding agencies that require ongoing research evidence on their effective management. Journal publications help effectively share and disseminate research results to inform policy and practice. We assess research investments to United Kingdom institutions in HIV, tuberculosis and malaria, and analyse these by numbers of publications and citations and by disease and type of science. Methods: Information on infection-related research investments awarded to United Kingdom institutions across 1997-2010 were sourced from funding agencies and individually categorised by disease and type of science. Publications were sourced from the Scopus database via keyword searches and filtered to include only publications relating to human disease and containing a United Kingdom-based first and/or last author. Data were matched by disease and type of science categories. Investment (United Kingdom pounds) and publications were compared to generate an 'investment per publication' metric; similarly, an 'investment per citation' metric was also developed as a measure of the usefulness of research. Results: Total research investment for all three diseases was £1.4 billion, and was greatest for HIV (£651.4 million), followed by malaria (£518.7 million) and tuberculosis (£239.1 million). There were 17,271 included publications, with 9,322 for HIV, 4,451 for malaria, and 3,498 for tuberculosis. HIV publications received the most citations (254,949), followed by malaria (148,559) and tuberculosis (100,244). According to UK pound per publication, tuberculosis (£50,691) appeared the most productive for investment, compared to HIV (£61,971) and malaria (£94,483). By type of science, public health research was most productive for HIV (£27,296) and tuberculosis (£22,273), while phase I-III trials were most productive for malaria (£60,491). According to UK pound per citation, tuberculosis (£1,797) was the most productive area for investment, compared to HIV (£2,265) and malaria (£2,834). Public health research was the most productive type of science for HIV (£2,265) and tuberculosis (£1,797), whereas phase I-III trials were most productive for malaria (£1,713). Conclusions: When comparing total publications and citations with research investment to United Kingdom institutions, tuberculosis research appears to perform best in terms of efficiency. There were more public health-related publications and citations for HIV and tuberculosis than other types of science. These findings demonstrate the diversity of research funding and outputs, and provide new evidence to inform research investment strategies for policymakers, funders, academic institutions, and healthcare organizations.Infectious Disease Research Networ
Don Juan Pond, Antarctica: Near-surface CaCl₂-brine feeding Earth's most saline lake and implications for Mars
The discovery on Mars of recurring slope lineae (RSL), thought to represent seasonal brines, has sparked interest in analogous environments on Earth. We report on new studies of Don Juan Pond (DJP), which exists at the upper limit of ephemeral water in the McMurdo Dry Valleys (MDV) of Antarctica, and is adjacent to several steep-sloped water tracks, the closest analog for RSL. The source of DJP has been interpreted to be deep groundwater. We present time-lapse data and meteorological measurements that confirm deliquescence within the DJP watershed and show that this, together with small amounts of meltwater, are capable of generating brines that control summertime water levels. Groundwater input was not observed. In addition to providing an analog for RSL formation, CaCl₂ brines and chloride deposits in basins may provide clues to the origin of ancient chloride deposits on Mars dating from the transition period from “warm/wet” to “cold/dry” climates
A coarse grained model of granular compaction and relaxation
We introduce a theoretical model for the compaction of granular materials by discrete vibrations which is expected to hold when the intensity of vibration is low. The dynamical unit is taken to be clusters of granules that belong to the same collective structure. We rigourously construct the model from first principles and show that numerical solutions compare favourably with a range of experimental results. This includes the logarithmic relaxation towards a statistical steady state, the effect of varying the intensity of vibration resulting in a so-called `annealing' curve, and the power spectrum of density fluctuations in the steady state itself. A mean-field version of the model is introduced which shares many features with the exact model and is open to quantitative analysi
European Dissemination of the Ultra-low Temperature Scale, PLTS-2000
Following the introduction of the provisional low-temperature scale from 0.9 mK to 1K, PLTS-2000, there is a need for primary and secondary thermometers and fixed points, which can disseminate the scale to users. This paper reports on the progress, within the EU collaborative project ‘ULT Dissemination’, in the development and evaluation of several devices with associated instrumentation. Principal among them are a current-sensing noise thermometer, a CMN thermometer adapted for industrial use, a Coulomb blockade thermometer, a second-sound thermometer, a 3He melting pressure thermometer for a direct realisation of the PLTS-2000. A superconductive reference device has also been developed, as a replacement for the NBS SRM-768 which is no longer available
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