Edutainment (semester?), IPRO 329: Edutainment IPRO 329 Midterm Report Sp05

This semester IPRO 329, Edutainment, turns its complete efforts toward an educational computer gaming suite targeted at fourth-grade students and the subjects these students struggle with most in school. It is tentatively entitled Scholars of the Lost Exhibit. Work on this project began last semester as the team completed their award-winning game College Pursuit. During this semester, we will focus on the design, development, testing, and marketing of Scholars of the Lost Exhibit.Deliverables for IPRO 329: Edutainment for the Spring 2005 semeste

Edutainment (semester?), IPRO 329: Edutainment IPRO 329 Poster 1 Sp05

This semester IPRO 329, Edutainment, turns its complete efforts toward an educational computer gaming suite targeted at fourth-grade students and the subjects these students struggle with most in school. It is tentatively entitled Scholars of the Lost Exhibit. Work on this project began last semester as the team completed their award-winning game College Pursuit. During this semester, we will focus on the design, development, testing, and marketing of Scholars of the Lost Exhibit.Deliverables for IPRO 329: Edutainment for the Spring 2005 semeste

Edutainment (semester?), IPRO 329: Edutainment IPRO 329 Project Plan Sp05

This semester IPRO 329, Edutainment, turns its complete efforts toward an educational computer gaming suite targeted at fourth-grade students and the subjects these students struggle with most in school. It is tentatively entitled Scholars of the Lost Exhibit. Work on this project began last semester as the team completed their award-winning game College Pursuit. During this semester, we will focus on the design, development, testing, and marketing of Scholars of the Lost Exhibit.Deliverables for IPRO 329: Edutainment for the Spring 2005 semeste

Edutainment (semester?), IPRO 329: Edutainment IPRO 329 Poster 2 Sp05

This semester IPRO 329, Edutainment, turns its complete efforts toward an educational computer gaming suite targeted at fourth-grade students and the subjects these students struggle with most in school. It is tentatively entitled Scholars of the Lost Exhibit. Work on this project began last semester as the team completed their award-winning game College Pursuit. During this semester, we will focus on the design, development, testing, and marketing of Scholars of the Lost Exhibit.Deliverables for IPRO 329: Edutainment for the Spring 2005 semeste

Edutainment (semester?), IPRO 329: Edutainment IPRO 329 Abstract Sp05

This semester IPRO 329, Edutainment, turns its complete efforts toward an educational computer gaming suite targeted at fourth-grade students and the subjects these students struggle with most in school. It is tentatively entitled Scholars of the Lost Exhibit. Work on this project began last semester as the team completed their award-winning game College Pursuit. During this semester, we will focus on the design, development, testing, and marketing of Scholars of the Lost Exhibit.Deliverables for IPRO 329: Edutainment for the Spring 2005 semeste

Edutainment (semester?), IPRO 329: Edutainment IPRO 329 Final Report Sp05

This semester IPRO 329, Edutainment, turns its complete efforts toward an educational computer gaming suite targeted at fourth-grade students and the subjects these students struggle with most in school. It is tentatively entitled Scholars of the Lost Exhibit. Work on this project began last semester as the team completed their award-winning game College Pursuit. During this semester, we will focus on the design, development, testing, and marketing of Scholars of the Lost Exhibit.Deliverables for IPRO 329: Edutainment for the Spring 2005 semeste

Edutainment (semester?), IPRO 329

This semester IPRO 329, Edutainment, turns its complete efforts toward an educational computer gaming suite targeted at fourth-grade students and the subjects these students struggle with most in school. It is tentatively entitled Scholars of the Lost Exhibit. Work on this project began last semester as the team completed their award-winning game College Pursuit. During this semester, we will focus on the design, development, testing, and marketing of Scholars of the Lost Exhibit.Deliverables for IPRO 329: Edutainment for the Spring 2005 semeste

Endocytosis Genes Facilitate Protein and Membrane Transport in C. elegans Sensory Cilia

BACKGROUND: Multiple intracellular transport pathways drive the formation, maintenance and function of cilia, a compartmentalised organelle associated with motility, chemo-/mechano-/photo-sensation, and developmental signaling. These pathways include cilium-based intraflagellar transport (IFT) and poorly understood membrane trafficking events. Defects in ciliary transport contribute to the aetiology of human ciliary disease such as Bardet-Biedl syndrome (BBS). In this study, we employ the genetically tractable nematode Caenorhabditis elegans to investigate if endocytosis genes function in cilium formation and/or the transport of ciliary membrane or ciliary proteins. RESULTS: Here we show that localisation of the clathrin light chain, AP-2 clathrin adaptor, dynamin and RAB-5 endocytic proteins overlaps with a morphologically discrete periciliary membrane compartment associated with sensory cilia. In addition, ciliary transmembrane proteins such as G protein-coupled receptors concentrate at periciliary membranes. Disruption of endocytic gene function causes expansion of ciliary and/or periciliary membranes as well as defects in the ciliary targeting and/or transport dynamics of ciliary transmembrane and IFT proteins. Finally, genetic analyses reveal that the ciliary membrane expansions in dynamin and AP-2 mutants require bbs-8 and rab-8 function, and that sensory signaling and endocytic genes may function in a common pathway to regulate ciliary membrane volume. CONCLUSIONS: These data implicate C. elegans endocytosis proteins localized at the ciliary base in regulating ciliary and periciliary membrane volume, and suggest that membrane retrieval from these compartments is counter-balanced by BBS-8 and RAB-8-mediated membrane delivery