Co-optimization of energy and reserve capacity considering renewable energy unit with uncertainty

This paper proposes a system model for optimal dispatch of the energy and reserve capacity considering uncertain load demand and unsteady power generation. This implicates uncertainty in managing the power demand along with the consideration of utility, user and environmental objectives. The model takes into consideration a day-ahead electricity market that involves the varying power demand bids and generates a required amount of energy in addition with reserve capacity. The lost opportunity cost is also considered and incorporated within the context of expected load not served. Then, the effects of combined and separate dispatching the energy and reserve are investigated. The nonlinear cost curves have been addressed by optimizing the objective function using robust optimization technique. Finally, various cases in accordance with underlying parameters have been considered in order to conduct and evaluate numerical results. Simulation results show the effectiveness of proposed scheduling model in terms of reduced cost and system stability

Future Greener Seaports:A Review of New Infrastructure, Challenges, and Energy Efficiency Measures

Recently, the application of renewable energy sources (RESs) for power distribution systems is growing immensely. This advancement brings several advantages, such as energy sustainability and reliability, easier maintenance, cost-effective energy sources, and ecofriendly. The application of RESs in maritime systems such as port microgrids massively improves energy efficiency and reduces the utilization of fossil fuels, which is a serious threat to the environment. Accordingly, ports are receiving several initiatives to improve their energy efficiency by deploying different types of RESs based on the power electronic converters. This paper conducts a systematic review to provide cutting-edge state-of-the-art on the modern electrification and infrastructure of seaports taking into account some challenges such as the environmental aspects, energy efficiency enhancement, renewable energy integration, and legislative and regulatory requirements. Moreover, the technological methods, including electrifications, digitalization, onshore power supply applications, and energy storage systems of ports, are addressed. Furthermore, details of some operational strategies such as energy-aware operations and peak-shaving are delivered. Besides, the infrastructure scheme to enhance the energy efficiency of modern ports, including port microgrids and seaport smart microgrids are delivered. Finally, the applications of nascent technologies in seaports are presented

Offshore Wind Farm-Grid Integration: A Review on Infrastructure, Challenges, and Grid Solutions

Recently, the penetration of renewable energy sources (RESs) into electrical power systems is witnessing a large attention due to their inexhaustibility, environmental benefits, storage capabilities, lower maintenance and stronger economy, etc. Among these RESs, offshore wind power plants (OWPP) are ones of the most widespread power plants that have emerged with regard to being competitive with other energy technologies. However, the application of power electronic converters (PECs), offshore transmission lines and large substation transformers result in considerable power quality (PQ) issues in grid connected OWPP. Moreover, due to the installation of filters for each OWPP, some other challenges such as voltage and frequency stability arise. In this regard, various customs power devices along with integration control methodologies have been implemented to deal with stated issues. Furthermore, for a smooth and reliable operation of the system, each country established various grid codes. Although various mitigation schemes and related standards for OWPP are documented separately, a comprehensive review covering these aspects has not yet addressed in the literature. The objective of this study is to compare and relate prior as well as latest developments on PQ and stability challenges and their solutions. Low voltage ride through (LVRT) schemes and associated grid codes prevalent for the interconnection of OWPP based power grid have been deliberated. In addition, various PQ issues and mitigation options such as FACTS based filters, DFIG based adaptive and conventional control algorithms, ESS based methods and LVRT requirements have been summarized and compared. Finally, recommendations and future trends for PQ improvement are highlighted at the end

On smart gaze based annotation of histopathology images for training of deep convolutional neural networks

Unavailability of large training datasets is a bottleneck that needs to be overcome to realize the true potential of deep learning in histopathology applications. Although slide digitization via whole slide imaging scanners has increased the speed of data acquisition, labeling of virtual slides requires a substantial time investment from pathologists. Eye gaze annotations have the potential to speed up the slide labeling process. This work explores the viability and timing comparisons of eye gaze labeling compared to conventional manual labeling for training object detectors. Challenges associated with gaze based labeling and methods to refine the coarse data annotations for subsequent object detection are also discussed. Results demonstrate that gaze tracking based labeling can save valuable pathologist time and delivers good performance when employed for training a deep object detector. Using the task of localization of Keratin Pearls in cases of oral squamous cell carcinoma as a test case, we compare the performance gap between deep object detectors trained using hand-labelled and gaze-labelled data. On average, compared to 'Bounding-box' based hand-labeling, gaze-labeling required 57.6% less time per label and compared to 'Freehand' labeling, gaze-labeling required on average 85% less time per label

Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial

Background: Tranexamic acid reduces surgical bleeding and reduces death due to bleeding in patients with trauma. Meta-analyses of small trials show that tranexamic acid might decrease deaths from gastrointestinal bleeding. We aimed to assess the effects of tranexamic acid in patients with gastrointestinal bleeding. Methods: We did an international, multicentre, randomised, placebo-controlled trial in 164 hospitals in 15 countries. Patients were enrolled if the responsible clinician was uncertain whether to use tranexamic acid, were aged above the minimum age considered an adult in their country (either aged 16 years and older or aged 18 years and older), and had significant (defined as at risk of bleeding to death) upper or lower gastrointestinal bleeding. Patients were randomly assigned by selection of a numbered treatment pack from a box containing eight packs that were identical apart from the pack number. Patients received either a loading dose of 1 g tranexamic acid, which was added to 100 mL infusion bag of 0·9% sodium chloride and infused by slow intravenous injection over 10 min, followed by a maintenance dose of 3 g tranexamic acid added to 1 L of any isotonic intravenous solution and infused at 125 mg/h for 24 h, or placebo (sodium chloride 0·9%). Patients, caregivers, and those assessing outcomes were masked to allocation. The primary outcome was death due to bleeding within 5 days of randomisation; analysis excluded patients who received neither dose of the allocated treatment and those for whom outcome data on death were unavailable. This trial was registered with Current Controlled Trials, ISRCTN11225767, and ClinicalTrials.gov, NCT01658124. Findings: Between July 4, 2013, and June 21, 2019, we randomly allocated 12 009 patients to receive tranexamic acid (5994, 49·9%) or matching placebo (6015, 50·1%), of whom 11 952 (99·5%) received the first dose of the allocated treatment. Death due to bleeding within 5 days of randomisation occurred in 222 (4%) of 5956 patients in the tranexamic acid group and in 226 (4%) of 5981 patients in the placebo group (risk ratio [RR] 0·99, 95% CI 0·82–1·18). Arterial thromboembolic events (myocardial infarction or stroke) were similar in the tranexamic acid group and placebo group (42 [0·7%] of 5952 vs 46 [0·8%] of 5977; 0·92; 0·60 to 1·39). Venous thromboembolic events (deep vein thrombosis or pulmonary embolism) were higher in tranexamic acid group than in the placebo group (48 [0·8%] of 5952 vs 26 [0·4%] of 5977; RR 1·85; 95% CI 1·15 to 2·98). Interpretation: We found that tranexamic acid did not reduce death from gastrointestinal bleeding. On the basis of our results, tranexamic acid should not be used for the treatment of gastrointestinal bleeding outside the context of a randomised trial

Towards sustainable tourism : analysis of stakeholder perspectives in Baltistan, Pakistan

The importance of the tourism industry is explicitly highlighted in United Nation’s SDGs. Sustainable tourism development is recognized as a useful tool for poverty reduction, social justice, environmental protection, and gender equality. Tourism is also one of the fastest-growing industries, providing employment opportunities to a large number of the world population, especially to the local people; women; and youth. The tourism industry has shown tremendous growth during the last six years in Baltistan. Therefore, to receive long-term benefits, detailed research was needed to study the impacts of tourism growth on the sustainability of the industry. Despite the immense tourism potential, the tourism industry of Baltistan has remained neglected by the Government of Pakistan, due to the disputed status it has. The tourism sector can bring revolutionary changes to the life of local inhabitants by formulating effective tourism policies. The scientific analysis based on actual market knowledge is essential to take right decisions. For this purpose, to generate local tourism knowledge, this study identifies the key stakeholders of the Baltistan tourism industry, the importance of tourism for the local population, the nature of current practices, and the problems preventing sustainable tourism growth from the perspectives of important stakeholders. Furthermore, this paper also provides detailed and relevant tourism knowledge from the literature, which include the evolutionary stages of tourism; the concept of sustainable tourism; and how tourism contributes to sustainable development. Qualitative methods were employed to conduct this research. For data collection, structured and unstructured interviews; and fieldwork methods were used. This paper concluded that increased tourism activities are generating several problems posing threat to the sustainability of the industry. Lack of research in this field was found the biggest hurdle in the formulation of effective policies. Lastly, this study recommends that constant monitoring of impacts is needed, and necessary remedial interventions are essential to reap the full benefits of tourism for a maximum period

Large-scale Data Integration Using Graph Probabilistic Dependencies (GPDs)

The diversity and proliferation of Knowledge bases have made data integration one of the key challenges in the data science domain. The imperfect representations of entities, particularly in graphs, add additional challenges in data integration. Graph dependencies (GDs) were investigated in existing studies for the integration and maintenance of data quality on graphs. However, the majority of graphs contain plenty of duplicates with high diversity. Consequently, the existence of dependencies over these graphs becomes highly uncertain. In this paper, we proposed graph probabilistic dependencies (GPDs) to address the issue of uncertainty over these large-scale graphs with a novel class of dependencies for graphs. GPDs can provide a probabilistic explanation for dealing with uncertainty while discovering dependencies over graphs. Furthermore, a case study is provided to verify the correctness of the data integration process based on GPDs. Preliminary results demonstrated the effectiveness of GPDs in terms of reducing redundancies and inconsistencies over the benchmark datasets.Data Science Research Centre (DSRC) at the University of Derb

A Multimodal Deep Log-Based User Experience (UX) Platform for UX Evaluation

The user experience (UX) is an emerging field in user research and design, and the development of UX evaluation methods presents a challenge for both researchers and practitioners. Different UX evaluation methods have been developed to extract accurate UX data. Among UX evaluation methods, the mixed-method approach of triangulation has gained importance. It provides more accurate and precise information about the user while interacting with the product. However, this approach requires skilled UX researchers and developers to integrate multiple devices, synchronize them, analyze the data, and ultimately produce an informed decision. In this paper, a method and system for measuring the overall UX over time using a triangulation method are proposed. The proposed platform incorporates observational and physiological measurements in addition to traditional ones. The platform reduces the subjective bias and validates the user’s perceptions, which are measured by different sensors through objectification of the subjective nature of the user in the UX assessment. The platform additionally offers plug-and-play support for different devices and powerful analytics for obtaining insight on the UX in terms of multiple participants

Multi-model-based interactive authoring environment for creating shareable medical knowledge

Technologically integrated healthcare environments can be realized if physicians are encouraged to use smart systems for the creation and sharing of knowledge used in clinical decision support systems (CDSS). While CDSSs are heading toward smart environments, they lack support for abstraction of technology-oriented knowledge from physicians. Therefore, abstraction in the form of a user-friendly and flexible authoring environment is required in order for physicians to create shareable and interoperable knowledge for CDSS workflows. Our proposed system provides a user-friendly authoring environment to create Arden Syntax MLM (Medical Logic Module) as shareable knowledge rules for intelligent decision-making by CDSS. Existing systems are not physician friendly and lack interoperability and shareability of knowledge. In this paper, we proposed Intelligent-Knowledge Authoring Tool (I-KAT), a knowledge authoring environment that overcomes the above mentioned limitations. Shareability is achieved by creating a knowledge base from MLMs using Arden Syntax. Interoperability is enhanced using standard data models and terminologies. However, creation of shareable and interoperable knowledge using Arden Syntax without abstraction increases complexity, which ultimately makes it difficult for physicians to use the authoring environment. Therefore, physician friendliness is provided by abstraction at the application layer to reduce complexity. This abstraction is regulated by mappings created between legacy system concepts, which are modeled as domain clinical model (DCM) and decision support standards such as virtual medical record (vMR) and Systematized Nomenclature of Medicine - Clinical Terms (SNOMED CT). We represent these mappings with a semantic reconciliation model (SRM). The objective of the study is the creation of shareable and interoperable knowledge using a user-friendly and flexible I-KAT. Therefore we evaluated our system using completeness and user satisfaction criteria, which we assessed through the system- and user-centric evaluation processes. For system-centric evaluation, we compared the implementation of clinical information modelling system requirements in our proposed system and in existing systems. The results suggested that 82.05% of the requirements were fully supported, 7.69% were partially supported, and 10.25% were not supported by our system. In the existing systems, 35.89% of requirements were fully supported, 28.20% were partially supported, and 35.89% were not supported. For user-centric evaluation, the assessment criterion was ‘ease of use’. Our proposed system showed 15 times better results with respect to MLM creation time than the existing systems. Moreover, on average, the participants made only one error in MLM creation using our proposed system, but 13 errors per MLM using the existing systems. We provide a user-friendly authoring environment for creation of shareable and interoperable knowledge for CDSS to overcome knowledge acquisition complexity. The authoring environment uses state-of-the-art decision support-related clinical standards with increased ease of use.Ministry of Science, ICT and Future Plannin

A unified graph model based on molecular data binning for disease subtyping.

Molecular disease subtype discovery from omics data is an important research problem in precision medicine.The biggest challenges are the skewed distribution and data variability in the measurements of omics data. These challenges complicate the efficient identification of molecular disease subtypes defined by clinical differences, such as survival. Existing approaches adopt kernels to construct patient similarity graphs from each view through pairwise matching. However, the distance functions used in kernels are unable to utilize the potentially critical information of extreme values and data variability which leads to the lack of robustness. In this paper, a novel robust distance metric (ROMDEX) is proposed to construct similarity graphs for molecular disease subtypes from omics data, which is able to address the data variability and extreme values challenges. The proposed approach is validated on multiple TCGA cancer datasets, and the results are compared with multiple baseline disease subtyping methods. The evaluation of results is based on Kaplan-Meier survival time analysis, which is validated using statistical tests e.g, Cox-proportional hazard (Cox p-value). We reject the null hypothesis that the cohorts have the same hazard, for the P-values less than 0.05. The proposed approach achieved best P-values of 0.00181, 0.00171, and 0.00758 for Gene Expression, DNA Methylation, and MicroRNA data respectively, which shows significant difference in survival between the cohorts. In the results, the proposed approach outperformed the existing state-of-the-art (MRGC, PINS, SNF, Consensus Clustering and Icluster+) disease subtyping approaches on various individual disease views of multiple TCGA datasets