505 research outputs found
The three-dimensional random field Ising magnet: interfaces, scaling, and the nature of states
The nature of the zero temperature ordering transition in the 3D Gaussian
random field Ising magnet is studied numerically, aided by scaling analyses. In
the ferromagnetic phase the scaling of the roughness of the domain walls,
, is consistent with the theoretical prediction .
As the randomness is increased through the transition, the probability
distribution of the interfacial tension of domain walls scales as for a single
second order transition. At the critical point, the fractal dimensions of
domain walls and the fractal dimension of the outer surface of spin clusters
are investigated: there are at least two distinct physically important fractal
dimensions. These dimensions are argued to be related to combinations of the
energy scaling exponent, , which determines the violation of
hyperscaling, the correlation length exponent , and the magnetization
exponent . The value is derived from the
magnetization: this estimate is supported by the study of the spin cluster size
distribution at criticality. The variation of configurations in the interior of
a sample with boundary conditions is consistent with the hypothesis that there
is a single transition separating the disordered phase with one ground state
from the ordered phase with two ground states. The array of results are shown
to be consistent with a scaling picture and a geometric description of the
influence of boundary conditions on the spins. The details of the algorithm
used and its implementation are also described.Comment: 32 pp., 2 columns, 32 figure
The Interspersed Spin Boson Lattice Model
We describe a family of lattice models that support a new class of quantum
magnetism characterized by correlated spin and bosonic ordering [Phys. Rev.
Lett. 112, 180405 (2014)]. We explore the full phase diagram of the model using
Matrix-Product-State methods. Guided by these numerical results, we describe a
modified variational ansatz to improve our analytic description of the
groundstate at low boson frequencies. Additionally, we introduce an
experimental protocol capable of inferring the low-energy excitations of the
system by means of Fano scattering spectroscopy. Finally, we discuss the
implementation and characterization of this model with current circuit-QED
technology.Comment: Submitted to EPJ ST issue on "Novel Quantum Phases and Mesoscopic
Physics in Quantum Gases
Direct comparison of phase-space distributions of K- and K+ mesons in heavy-ion collisions at SIS energies - evidence for in-medium modifications of kaons ?
The ratio of K- to K+ meson yields has been measured in the systems RuRu at
1.69 A GeV, Ru+Zr at 1.69 A GeV, and Ni+Ni at 1.93 A GeV incident beam kinetic
energy. The yield ratio is observed to vary across the measured phase space.
Relativistic transport-model calculations indicate that the data are best
understood if in-medium modifications of the kaons are taken into account.Comment: 14 pages including 3 figure
Panspermia, Past and Present: Astrophysical and Biophysical Conditions for the Dissemination of Life in Space
Astronomically, there are viable mechanisms for distributing organic material
throughout the Milky Way. Biologically, the destructive effects of ultraviolet
light and cosmic rays means that the majority of organisms arrive broken and
dead on a new world. The likelihood of conventional forms of panspermia must
therefore be considered low. However, the information content of dam-aged
biological molecules might serve to seed new life (necropanspermia).Comment: Accepted for publication in Space Science Review
Sideward flow of K+ mesons in Ru+Ru and Ni+Ni reactions near threshold
Experimental data on K+ meson and proton sideward flow measured with the FOPI
detector at SIS/GSI in the reactions Ru+Ru at 1.69 AGeV and Ni+Ni at 1.93 AGeV
are presented. The K+ sideward flow is found to be anti-correlated (correlated)
with the one of protons at low (high) transverse momenta. When compared to the
predictions of a transport model, the data favour the existence of an in-medium
repulsive K+ nucleon potential.Comment: 16 pages Revtex, 3 ps-figures, submitted to Phys. Lett.
Fluorouracil leucovorin and oxaliplatin with and without cetuximab in the first-line treatment of metastatic colorectal cancer
Purpose
This randomized study assessed whether the best overall response rate (ORR) of cetuximab combined with oxaliplatin, leucovorin, and fluorouracil (FOLFOX-4) was superior to that of FOLFOX-4 alone as first-line treatment for metastatic colorectal cancer. The influence of KRAS mutation status was investigated.
Patients and Methods
Patients received cetuximab (400 mg/m(2) initial dose followed by 250 mg/m(2)/wk thereafter) plus FOLFOX-4 (oxaliplatin 85 mg/m(2) on day 1, plus leucovorin 200 mg/m(2) and fluorouracil as a 400 mg/m(2) bolus followed by a 600 mg/m(2) infusion during 22 hours on days 1 and 2; n = 169) or FOLFOX-4 alone (n = 168). Treatment was continued until disease progression or unacceptable toxicity. KRAS mutation status was assessed in the subset of patients with assessable tumor samples (n = 233).
Results
The confirmed ORR for cetuximab plus FOLFOX-4 was higher than with FOLFOX-4 alone (46% v 36%). A statistically significant increase in the odds for a response with the addition of cetuximab to FOLFOX-4 could not be established (odds ratio = 1.52; P = .064). In patients with KRAS wild-type tumors, the addition of cetuximab to FOLFOX-4 was associated with a clinically significant increased chance of response (ORR = 61% v 37%; odds ratio = 2.54; P = .011) and a lower risk of disease progression (hazard ratio = 0.57; P = .0163) compared with FOLFOX-4 alone. Cetuximab plus FOLFOX-4 was generally well tolerated.
Conclusion
KRAS mutational status was shown to be a highly predictive selection criterion in relation to the treatment decision regarding the addition of cetuximab to FOLFOX-4 for previously untreated patients with metastatic colorectal cancer
Observation of Scaling Violations in Scaled Momentum Distributions at HERA
Charged particle production has been measured in deep inelastic scattering
(DIS) events over a large range of and using the ZEUS detector. The
evolution of the scaled momentum, , with in the range 10 to 1280
, has been investigated in the current fragmentation region of the Breit
frame. The results show clear evidence, in a single experiment, for scaling
violations in scaled momenta as a function of .Comment: 21 pages including 4 figures, to be published in Physics Letters B.
Two references adde
Quantum magnetism in two dimensions: From semi-classical N\'eel order to magnetic disorder
This is a review of ground-state features of the s=1/2 Heisenberg
antiferromagnet on two-dimensional lattices. A central issue is the interplay
of lattice topology (e.g. coordination number, non-equivalent nearest-neighbor
bonds, geometric frustration) and quantum fluctuations and their impact on
possible long-range order. This article presents a unified summary of all 11
two-dimensional uniform Archimedean lattices which include e.g. the square,
triangular and kagome lattice. We find that the ground state of the spin-1/2
Heisenberg antiferromagnet is likely to be semi-classically ordered in most
cases. However, the interplay of geometric frustration and quantum fluctuations
gives rise to a quantum paramagnetic ground state without semi-classical
long-range order on two lattices which are precisely those among the 11 uniform
Archimedean lattices with a highly degenerate ground state in the classical
limit. The first one is the famous kagome lattice where many low-lying singlet
excitations are known to arise in the spin gap. The second lattice is called
star lattice and has a clear gap to all excitations.
Modification of certain bonds leads to quantum phase transitions which are
also discussed briefly. Furthermore, we discuss the magnetization process of
the Heisenberg antiferromagnet on the 11 Archimedean lattices, focusing on
anomalies like plateaus and a magnetization jump just below the saturation
field. As an illustration we discuss the two-dimensional Shastry-Sutherland
model which is used to describe SrCu2(BO3)2.Comment: This is now the complete 72-page preprint version of the 2004 review
article. This version corrects two further typographic errors (three total
with respect to the published version), see page 2 for detail
D* Production in Deep Inelastic Scattering at HERA
This paper presents measurements of D^{*\pm} production in deep inelastic
scattering from collisions between 27.5 GeV positrons and 820 GeV protons. The
data have been taken with the ZEUS detector at HERA. The decay channel
(+ c.c.) has been used in the study. The
cross section for inclusive D^{*\pm} production with
and is 5.3 \pms 1.0 \pms 0.8 nb in the kinematic region
{ GeV and }. Differential cross
sections as functions of p_T(D^{*\pm}), and are
compared with next-to-leading order QCD calculations based on the photon-gluon
fusion production mechanism. After an extrapolation of the cross section to the
full kinematic region in p_T(D^{*\pm}) and (D^{*\pm}), the charm
contribution to the proton structure function is
determined for Bjorken between 2 10 and 5 10.Comment: 17 pages including 4 figure
- …