Digestion, rumen fermentation and circulating concentrations of insulin, growth hormone and IGF-1 in steers fed diets based on different proportions of maize silage and grass silage

Replacing grass silage with maize silage results in a fundamental change in the ratio of structural to non-structural carbohydrates with commensurate changes in rumen fermentation patterns and nutrient utilisation. This study investigated the effects of feeding four forage mixtures, namely grass silage (G); 67 g/100 g grass silage133 g/100 g maize silage (GGM); 67 g/100 g maize silage133/100 g grass silage (MMG); maize silage (M) to four ruminally and duodenally canulated Holstein Friesian steers. All diets were formulated to be isonitrogenous (22.4 g N/kg DM) using a concentrate mixture. Dietary dry matter (DM) and organic matter (OM) digestibility increased with ascending maize silage inclusion (P,0.1) whereas starch and neutral detergent fibre digestibility declined (P,0.05). Ratio of non-glucogenic to glucogenic precursors in the rumen fluid increased with maize silage inclusion (P,0.01) with a commensurate reduction in rumen pH (P,0.05). Mean circulating concentrations of insulin were greatest and similar in diets MMG and GGM, lower in diet M and lowest in diet G (P,0.01). There were no effects of diet on the mean circulating concentration of growth hormone (GH), or the frequency, amplitude and duration of GH pulses, or the mean circulating concentrations of IGF-1. Increasing levels of DM, OM and starch intakes with the substitution of grass silage with maize silage affected overall digestion, nutrient partitioning and subsequent circulating concentrations of insulin

Preceding rule induction with instance reduction methods

A new prepruning technique for rule induction is presented which applies instance reduction before rule induction. An empirical evaluation records the predictive accuracy and size of rule-sets generated from 24 datasets from the UCI Machine Learning Repository. Three instance reduction algorithms (Edited Nearest Neighbour, AllKnn and DROP5) are compared. Each one is used to reduce the size of the training set, prior to inducing a set of rules using Clark and Boswell's modification of CN2. A hybrid instance reduction algorithm (comprised of AllKnn and DROP5) is also tested. For most of the datasets, pruning the training set using ENN, AllKnn or the hybrid significantly reduces the number of rules generated by CN2, without adversely affecting the predictive performance. The hybrid achieves the highest average predictive accuracy

Perturbative QCD at non-zero chemical potential: Comparison with the large-Nf limit and apparent convergence

The perturbative three-loop result for the thermodynamic potential of QCD at finite temperature and chemical potential as obtained in the framework of dimensional reduction is compared with the exact result in the limit of large flavor number. The apparent convergence of the former as well as possibilities for optimization are investigated. Corresponding optimized results for full QCD are given for the case of two massless quark flavors.Comment: REVTEX4, 4 pages, 3 color figures. v2: fig. 3 now includes also lattice data for two-flavor QCD at nonzero chemical potentia

Remarks on the multi-parameter reweighting method for the study of lattice QCD at non-zero temperature and density

We comment on the reweighting method for the study of finite density lattice QCD. We discuss the applicable parameter range of the reweighting method for models which have more than one simulation parameter. The applicability range is determined by the fluctuations of the modification factor of the Boltzmann weight. In some models having a first order phase transition, the fluctuations are minimized along the phase transition line if we assume that the pressure in the hot and the cold phase is balanced at the first order phase transition point. This suggests that the reweighting method with two parameters is applicable in a wide range for the purpose of tracing out the phase transition line in the parameter space. To confirm the usefulness of the reweighting method for 2 flavor QCD, the fluctuations of the reweighting factor are measured by numerical simulations for the cases of reweighting in the quark mass and chemical potential directions. The relation with the phase transition line is discussed. Moreover, the sign problem caused by the complex phase fluctuations is studied.Comment: 20 page, 6 figure

Responses of hadrons to chemical potential at finite temperature

We present a framework to compute the responses of hadron masses to the chemical potential in lattice QCD simulations. As a first trial, the screening mass of the pseudoscalar meson and its first and second responses are evaluated. We present results on a $16\times 8^2\times 4$ lattice with two flavors of staggered quarks below and above $T_c$. The responses to both the isoscalar and isovector chemical potentials are obtained. They show different behavior in the low and the high temperature phases, which may be explained as a consequence of chiral symmetry breaking and restoration, respectively.Comment: 10 pages, 11 figure

The QCD thermal phase transition in the presence of a small chemical potential

We propose a new method to investigate the thermal properties of QCD with a small quark chemical potential $\mu$. Derivatives of the phase transition point with respect to $\mu$ are computed at $\mu=0$ for 2 flavors of p-4 improved staggered fermions with $ma=0.1,0.2$ on a $16^3\times4$ lattice. The resulting Taylor expansion is well behaved for the small values of $\mu_{\rm q}/T_c\sim0.1$ relevant for RHIC phenomenology, and predicts a critical curve $T_c(\mu)$ in reasonable agreement with estimates obtained using exact reweighting. In addition, we contrast the case of isoscalar and isovector chemical potentials, quantify the effect of $\mu\not=0$ on the equation of state, and comment on the complex phase of the fermion determinant in QCD with $\mu\not=0$.Comment: 26 pages, 25 figures, minor modificatio

Thermodynamics of Large-N_f QCD at Finite Chemical Potential

We extend the previously obtained results for the thermodynamic potential of hot QCD in the limit of large number of fermions to non-vanishing chemical potential. We give exact results for the thermal pressure in the entire range of temperature and chemical potential for which the presence of a Landau pole is negligible numerically. In addition we compute linear and non-linear quark susceptibilities at zero chemical potential, and the entropy at small temperatures. We compare with the available perturbative results and determine their range of applicability. Our numerical accuracy is sufficiently high to check and verify existing results, including the recent perturbative results by Vuorinen on quark number susceptibilities and the older results by Freedman and McLerran on the pressure at zero temperature and high chemical potential. We also obtain a number of perturbative coefficients at sixth order in the coupling that have not yet been calculated analytically. In the case of both non-zero temperature and non-zero chemical potential, we investigate the range of validity of a scaling behaviour noticed recently in lattice calculations by Fodor, Katz, and Szabo at moderately large chemical potential and find that it breaks down rather abruptly at $\mu_q \gtrsim \pi T$, which points to a presumably generic obstruction for extrapolating data from small to large chemical potential. At sufficiently small temperatures $T \ll \mu_q$, we find dominating non-Fermi-liquid contributions to the interaction part of the entropy, which exhibits strong nonlinearity in the temperature and an excess over the free-theory value.Comment: 18 pages, 7 figures, JHEP style; v2: several updates, rewritten and extended sect. 3.4 covering now "Entropy at small temperatures and non-Fermi-liquid behaviour"; v3: additional remarks at the end of sect. 3.4; v4: minor corrections and additions (version to appear in JHEP

On the mechanisms governing gas penetration into a tokamak plasma during a massive gas injection

A new 1D radial fluid code, IMAGINE, is used to simulate the penetration of gas into a tokamak plasma during a massive gas injection (MGI). The main result is that the gas is in general strongly braked as it reaches the plasma, due to mechanisms related to charge exchange and (to a smaller extent) recombination. As a result, only a fraction of the gas penetrates into the plasma. Also, a shock wave is created in the gas which propagates away from the plasma, braking and compressing the incoming gas. Simulation results are quantitatively consistent, at least in terms of orders of magnitude, with experimental data for a D 2 MGI into a JET Ohmic plasma. Simulations of MGI into the background plasma surrounding a runaway electron beam show that if the background electron density is too high, the gas may not penetrate, suggesting a possible explanation for the recent results of Reux et al in JET (2015 Nucl. Fusion 55 093013)

Management of Patients With Crohn's Disease and Ulcerative Colitis During the Coronavirus Disease-2019 Pandemic: Results of an International Meeting

The International Organization for the Study of Inflammatory Bowel Diseases (IOIBD) is the only global organization devoted to the study of and management of the inflammatory bowel diseases (IBDs), namely, Crohn?s disease and ulcerative colitis. Membership is composed of physician-scientists who have established expertise in these diseases. The organization hosts an annual meeting and a number of working groups addressing issues of the epidemiology of IBD, diet and nutrition, and the development and use of treatments for IBD. There are currently 89 members of IOIBD representing 26 different countries. The organization has taken particular interest in the coronavirus disease-2019 (COVID-19) pandemic and how it may affect the IBD patient population. This document summarizes the results of 2 recent virtual meetings of the group and subsequent expert guidance for patients and providers