6,365 research outputs found

    Comparison of life history parameters for landed and discarded fish captured off the southeastern United States

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    Commercial fisheries that are managed with minimum size limits protect small fish of all ages and may affect size-selective mortality by the differential removal of fast growing fish. This differential removal may decrease the average size at age, maturation, or sexual transition of the exploited population. When fishery-independent data are not available, a comparison of life history parameters of landed with those of discarded fish (by regulation) will indicate if differential mortality is occurring with the capture of young but large fish (fast growing phenotypes). Indications of this differential size-selective mortality would include the following: the discarded portion of the target fish would have similar age ranges but smaller sizes at age, maturation, and sexual transition as that of landed fish. We examined three species with minimum size limits but different exploitation histories. The known heavily exploited species (Rhomboplites aurorubens [vermilion snapper] and Pagrus pagrus [red porgy]) show signs of this differential mortality. Their landed catch includes many young, large fish, whereas discarded fish had a similar age range and mean ages but smaller sizes at age than the landed fish. The unknown exploited species, Mycteroperca phenax (scamp), showed no signs of differential mortality due to size-selective fishing. Landed catch consisted of old, large fish and discarded scamp had little overlap in age ranges, had significantly different mean ages, and only small differences in size at age when compared to comparable data for landed fish

    Testing for a unit root in the presence of a possible break in trend

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    In this paper we consider the issue of testing a time series for a unit root in the possible presence of a break in a linear deterministic trend at some unknown point in the series. We propose a break fraction estimator which, in the presence of a break in trend, is consistent for the true break fraction at rate Op(T^-1) when there is either a unit root or near-unit root in the stochastic component of the series. In contrast to other estimators available in the literature, when there is no break in trend, our proposed break fraction estimator converges to zero at rate Op(T^-1/2). Used in conjunction with a quasi difference (QD) detrended unit root test that incorporates a trend break regressor in the deterministic component, we show that these rates of convergence ensure that known break fraction null critical values are applicable asymptotically. Unlike available procedures in the literature this holds even if there is no break in trend (the true break fraction is zero), in which case the trend break regressor is dropped from the deterministic component and standard QD detrended unit root test critical values then apply. We also propose a second testing procedure which makes use of a formal pre-test for a trend break in the series, including a trend break regressor only where the pre-test rejects the null of no break. Both procedures ensure that the correctly sized (near-) efficient unit root test that allows (does not allow) for a break in trend is applied in the limit when a trend break does (does not) occur.Unit root test; quasi difference de-trending; trend break; pre-test; asymptotic power

    An Approach To The Delineation Of Banking Markets

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    The accurate delineation of banking markets is a necessary prerequisite to an analysis of the competitive environment in banking, the operational and allocation efficiency of our banking system, and policy prescriptions for structural change in the banking industry. While delineation constitutes a crucial foundation for analyses of competition, it appears that in practice current delineation techniques at best may be inconsistent, and at worst completely devoid of economic rationale..

    Чверть століття на ниві освіти

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    Наталія Купріянівна Місяць – відомий український вчений-мовознавець, викладач та організатор освіти на Житомирщині. Чверть століття, починаючи вже з далекого 1975 року, життя та діяльність Наталії Куприянівні тісно пов’язані з філологічним факультетом Житомирського едуніверситету імені Івана Франка

    An updated interactive database for 1692 genetic variants in coagulation Factor IX provides detailed insights into haemophilia B

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    BACKGROUND: Genetic variants in coagulation factor IX (FIX) are associated with haemophilia B, a rare bleeding disease. F9 variants are widespread across the gene and were summarised in our FIX variant database introduced in 2013. OBJECTIVE: We rationalise the molecular basis for 598 new F9 variants and 1645 new clinical cases, making a total of 1692 F9 variants and 5358 related patient cases. METHODS: New F9 variants were identified from publications and on-line resources, and compiled into a MySQL database for comparison with the human FIXa protein structure. RESULTS: The new total of 1692 F9 variants correspond to 406 (88%) of the 461 FIX residues and now include 70 additional residues. These comprise 945 unique point variants, 281 deletions, 352 polymorphisms, 63 insertions, and 51 others. Most FIX variants were point variants, although their proportion (56%) has reduced compared to 2013 (73%), while the proportion of polymorphisms has increased from 5% to 21%.The 764 unique mild severity variants in the mature protein with known phenotypes include 74 (9.7%) quantitative type I variants and 116 (15.2%) predominantly qualitative type II variants. The remaining 574 variants types are unspecified. Inhibitors are associated with 152 haemophilia B cases out of 5358 patients (2.8%), an increase of 93 from the previous database. CONCLUSION: The even distribution of the F9 variants revealed few mutational hotspots, and most variants were associated with small perturbations in the FIX protein structure. The updated database will assist clinicians and researchers in assessing treatments for haemophilia B patients

    Diluted Networks of Nonlinear Resistors and Fractal Dimensions of Percolation Clusters

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    We study random networks of nonlinear resistors, which obey a generalized Ohm's law, VIrV\sim I^r. Our renormalized field theory, which thrives on an interpretation of the involved Feynman Diagrams as being resistor networks themselves, is presented in detail. By considering distinct values of the nonlinearity r, we calculate several fractal dimensions characterizing percolation clusters. For the dimension associated with the red bonds we show that dred=1/νd_{\scriptsize red} = 1/\nu at least to order {\sl O} (\epsilon^4), with ν\nu being the correlation length exponent, and ϵ=6d\epsilon = 6-d, where d denotes the spatial dimension. This result agrees with a rigorous one by Coniglio. Our result for the chemical distance, d_{\scriptsize min} = 2 - \epsilon /6 - [ 937/588 + 45/49 (\ln 2 -9/10 \ln 3)] (\epsilon /6)^2 + {\sl O} (\epsilon^3) verifies a previous calculation by one of us. For the backbone dimension we find D_B = 2 + \epsilon /21 - 172 \epsilon^2 /9261 + 2 (- 74639 + 22680 \zeta (3))\epsilon^3 /4084101 + {\sl O} (\epsilon^4), where ζ(3)=1.202057...\zeta (3) = 1.202057..., in agreement to second order in ϵ\epsilon with a two-loop calculation by Harris and Lubensky.Comment: 29 pages, 7 figure

    Model organism databases: essential resources that need the support of both funders and users.

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    Modern biomedical research depends critically on access to databases that house and disseminate genetic, genomic, molecular, and cell biological knowledge. Even as the explosion of available genome sequences and associated genome-scale data continues apace, the sustainability of professionally maintained biological databases is under threat due to policy changes by major funding agencies. Here, we focus on model organism databases to demonstrate the myriad ways in which biological databases not only act as repositories but actively facilitate advances in research. We present data that show that reducing financial support to model organism databases could prove to be not just scientifically, but also economically, unsound

    Impact of a carbohydrate mouth rinse on corticomotor excitability after mental fatigue in healthy college-aged subjects

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    Mental Fatigue (MF) has been associated with reduced physical performance but the mechanisms underlying this result are unclear. A reduction in excitability of the corticomotor system is a way mental fatigue could negatively impact physical performance. Carbohydrate (CHO) mouth rinse (MR) has been shown to increase corticomotor excitability. The purpose of this study was to determine if CHO MR impacts corticomotor excitability after MF. Fifteen subjects (nine females, six males; age = 23 ± 1 years; height = 171 ± 2 cm; body mass = 69 ± 3 kg; BMI = 23.8 ± 0.7) completed two sessions under different MR conditions (Placebo (PLAC), 6.4% glucose (CHO)) separated by at least 48 h and applied in a double-blinded randomized fashion. Motor-evoked potential (MEP) of the left first dorsal interosseous (FDI) was determined by transcranial magnetic stimulation (TMS) before and after MF. Perceived MF was recorded before and after the MF task using a 100 mm visual analog scale (VAS). MF was greater following PLAC (+30.4 ± 4.0 mm) than CHO (+19.4 ± 3.9 mm) ( = 0.005). MEP was reduced more following PLAC (-16.6 ± 4.4%) than CHO (-3.7 ± 4.7%) ( < 0.001). CHO MR was successful at attenuating the reduction in corticomotor excitability after MF. Carbohydrate mouth rinse may be a valuable tool at combating the negative consequences of mental fatigue
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