4,962 research outputs found

    LPWM expert: An expert system for water management during land preparation in a paddy estate in Malaysia.

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    Seberang Perak paddy estate, Malaysia, which practices intensive mechanized farming still uses the traditional approach in decision-making. Water management during land preparation, the critical process to be completed within scheduled duration, needs better and quick management decisions for many alternative scenarios. A method proposed to encapsulate specific knowledge available with domain experts and generated through modeling to an expert system (Land Preparation Water Management (LPWM) Expert) is outlined. The LPWM expert consists a database, a model base, a knowledge base and a user interface. Knowledge was gathered through discussions and interviews with domain experts. Collected quantitative data were used in modeling canal flows and water balance to extract knowledge for different possible scenarios. Knowledge base represent extracted knowledge as rules. All the rules in IF-THEN structure and syntax are verified with the help of wxCLIPS debugging capability. The results generated by the LPWM expert are validated with the domain experts. The expert system proposes decisions for many combinations of scenarios considering all the possible variations in rain, irrigation water supply, secondary blocks, sub-estates, cropping seasons and cropping intensity. The LPWM expert is user friendly and efficient where the outputs are supported with graphics

    The impact of work autonomy on job satisfaction of academic staff: an empirical examination of government universities in Sri Lanka

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    This study intends to examine whether work autonomy impacts academic staff members’ job satisfaction of state universities in Sri Lanka. As the research approach, a quantitative approach was employed. In collecting data, a structured questionnaire was used to collect responses from fifteen government universities in Sri Lanka. The multi-stage stratified random sampling method was applied to select a representative sample; and 423 usable questionnaires deemed appropriate for analysis were selected. The validity and reliability tests indicated that the measurement scales met the acceptable standards. The t-test and One-way ANOVA results indicated that depending on the selected demographic factors, current working status, gender, age, and highest level of education the perception on work autonomy of the academic staff members in state universities in Sri Lanka differs. Nevertheless, it was found that marital status and number of children had no impact on the perception of work autonomy. In terms of the regression analysis conducted, it was found out that the work autonomy was a highly significant factor affecting the academic staff members’ overall job satisfaction of state universities in Sri Lanka. This finding is expected to have significant policy implications

    A pragmatic randomised controlled trial of healing therapy in a gastroenterology outpatient setting

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    Introduction: To determine the benefits of healing therapy (spiritual healing) as an adjunct to conventional management in irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). Methods: 200 outpatients with IBS or IBD were randomised to either conventional treatment (control) or conventional plus five sessions of healing therapy (intervention). After 12 weeks controls also had healing therapy. Outcomes used were, the Measure Yourself Medical Outcomes Profile (MYMOP). IBS-QOL, IBDQ, and symptom measures. Results: There was a significant improvement in the MYMOP score at week 6 (p < 0.001) which was maintained to week 12 (p < 0.001) and 24 (p < 0.001). Improvements in MYMOP were significantly greater in the intervention group at both 6 (p < 0.001) and 12 weeks (p < 0.001) with effect sizes of 0.7 (95% CI: 0.4–1.1) and 0.8 (95% CI: 0.4–1.2). Condition-specific data for IBS showed that most QoL dimensions had a significant minimum 10-point score improvement at 6 and 12 weeks. The overall score improvement was 12.9 units at week 6 (p < 0.001), 12.4 units at week 12 (p < 0.001) and 13.8 units at week 24 (p < 0.001). In IBD there was also similar score improvement, but only up to week 12 were there associations of improved social and bowel functions (p < 0.001, respectively). Between group differences were identified for QoL scores in IBS at both week 6 (p < 0.001) and 12 (p < 0.001) but only for week 12 (p < 0.001) in the IBD group. Conclusions: The addition of healing therapy to conventional treatment was associated with improvement in symptoms and QoL in IBS, and to a lesser extent in IBD

    Effect of cuscuta reflexa stem and calotropis procera leaf extracts on glucose tolerance in glucose-induced hyperglycemic rats and mice

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    Cuscuta reflexa (whole plant) and Calotropis procera (leaves) are used in folk medicine of Bangladesh to control blood sugar in patients suffering from diabetes mellitus. The hypoglycemic effects of methanol and chloroform extracts of whole plants of Cuscuta reflexa, and methanol extract of leaves of Calotropis procera were investigated in oral glucose tolerance tests in Long Evans rats and Swiss albino mice, respectively. Both methanol and chloroform extracts of Cuscuta reflexa whole plant demonstrated significant oral hypoglycemic activity in glucose-loaded rats at doses of 50, 100 and 200 mg/kg body weight. The methanol extract of leaves of Calotropis procera, when tested at doses of 100 and 250 mg/kg body weight did not demonstrate any oral hypoglycemic effect when tested in glucose-loaded mice.Key words: Cuscuta reflexa, Calotropis procera, hypoglycemic activity, oral glucose tolerance test

    Asymmetric Fermi superfluid in a harmonic trap

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    We consider a dilute two-component atomic fermion gas with unequal populations in a harmonic trap potential using the mean field theory and the local density approximation. We show that the system is phase separated into concentric shells with the superfluid in the core surrounded by the normal fermion gas in both the weak-coupling BCS side and near the Feshbach resonance. In the strong-coupling BEC side, the composite bosons and left-over fermions can be mixed. We calculate the cloud radii and compare axial density profiles systemically for the BCS, near resonance and BEC regimes.Comment: 15 pages, 5 figure

    Phytochemicals Induce Apoptosis By Modulation Of Nitric Oxide Signaling Pathway In Cervical Cancer Cells

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    OBJECTIVE: Nitric Oxide (NO) is produced by NO synthases (NOS) and is a key signaling molecule that regulates tumorigenesis, both aiding and alleviating it. Elevated NO levels are cytotoxic to cancer cells, making NOS an important target for cancer treatment. In the present study, the modulatory effects of the phytochemicals, quercetin, sulforaphane, genistein, and epigallocatechin-3-gallate on NO pathway and apoptosis were shown in HeLa cervical cancer cells. MATERIALS AND METHODS: Fluorescent microscopy and flow cytometry were used to assess apoptosis. A Griess assay was used to quantitatively measure NO, quantitative PCR array was used to assess the expression levels of genes involved in the NO signaling pathway, and immunocytochemistry was used to determine NOS protein expression. The functional association among the modulated genes was evaluated using network biology analysis. gene set enrichment, and KEGG pathway analysis. RESULTS: Treatment with the phytochemicals elevated NO levels in HeLa cells and modulated various genes involved in nitric oxide biosynthesis, superoxide metabolism. and oxidative stress, including NOS1, NOS2, NOS3, ALOX12, and SOD2, with a concomitant increase in NOS2 and NOS3 protein expression levels: also. the phytochemicals were found to induce apoptosis. CONCLUSIONS: These results suggest that the phytochemical-induced cell death is partially attributed to the activation of the NO pathway and upregulation of pro-oxidant ROS generators. Further experimental studies are required to explore this mechanistic association of NO signaling pathway activation and induction of apoptosis in other types of cancer

    Entanglement between particle partitions in itinerant many-particle states

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    We review `particle partitioning entanglement' for itinerant many-particle systems. This is defined as the entanglement between two subsets of particles making up the system. We identify generic features and mechanisms of particle entanglement that are valid over whole classes of itinerant quantum systems. We formulate the general structure of particle entanglement in many-fermion ground states, analogous to the `area law' for the more usually studied entanglement between spatial regions. Basic properties of particle entanglement are first elucidated by considering relatively simple itinerant models. We then review particle-partitioning entanglement in quantum states with more intricate physics, such as anyonic models and quantum Hall states.Comment: review, about 20 pages. Version 2 has minor revisions

    Campylobacter infection and household factors are associated with childhood growth in urban Bangladesh : an analysis of the MAL-ED study

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    The dual burden of enteric infection and childhood malnutrition continues to be a global health concern and a leading cause of morbidity and death among children. Campylobacter infection, in particular, is highly prevalent in low- and middle-income countries, including Bangladesh. We examined longitudinal data to evaluate the trajectories of change in child growth, and to identify associations with Campylobacter infection and household factors. The study analyzed data from 265 children participating in the MAL-ED Study in Mirpur, Bangladesh. We applied latent growth curve modelling to evaluate the trajectories of change in children’s height, as measured by length-for-age z-score (LAZ), from age 0–24 months. Asymptomatic and symptomatic Campylobacter infections were included as 3- and 6-month lagged time-varying covariates, while household risk factors were included as time-invariant covariates. Maternal height and birth order were positively associated with LAZ at birth. An inverse association was found between increasing age and LAZ. Campylobacter infection prevalence increased with age, with over 70% of children 18–24 months of age testing positive for infection. In the final model, Campylobacter infection in the preceding 3-month interval was negatively associated with LAZ at 12, 15, and 18 months of age; similarly, infection in the preceding 6-month interval was negatively associated with LAZ at 15, 18, and 21 months of age. Duration of antibiotic use and access to treated drinking water were negatively associated with Campylobacter infection, with the strength of the latter effect increasing with children’s age. Campylobacter infection had a significant negative effect on child’s growth and this effect was most powerful between 12 and 21 months. The treatment of drinking water and increased antibiotic use have a positive indirect effect on linear child growth trajectory, acting via their association with Campylobacter infection

    A New Approach to Analyzing Patterns of Collaboration in Co-authorship Networks - Mesoscopic Analysis and Interpretation

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    This paper focuses on methods to study patterns of collaboration in co-authorship networks at the mesoscopic level. We combine qualitative methods (participant interviews) with quantitative methods (network analysis) and demonstrate the application and value of our approach in a case study comparing three research fields in chemistry. A mesoscopic level of analysis means that in addition to the basic analytic unit of the individual researcher as node in a co-author network, we base our analysis on the observed modular structure of co-author networks. We interpret the clustering of authors into groups as bibliometric footprints of the basic collective units of knowledge production in a research specialty. We find two types of coauthor-linking patterns between author clusters that we interpret as representing two different forms of cooperative behavior, transfer-type connections due to career migrations or one-off services rendered, and stronger, dedicated inter-group collaboration. Hence the generic coauthor network of a research specialty can be understood as the overlay of two distinct types of cooperative networks between groups of authors publishing in a research specialty. We show how our analytic approach exposes field specific differences in the social organization of research.Comment: An earlier version of the paper was presented at ISSI 2009, 14-17 July, Rio de Janeiro, Brazil. Revised version accepted on 2 April 2010 for publication in Scientometrics. Removed part on node-role connectivity profile analysis after finding error in calculation and deciding to postpone analysis

    Dynamical Relativistic Effects in Photoionization: Spin-Orbit-Resolved Angular Distributions of Xenon 4d Photoelectrons Near the Cooper Minimum

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    Two decades ago, it was predicted [Y. S. Kim et al., Phys. Rev. Lett. 46, 1326 (1981)] that relativistic effects should alter the dynamics of the photoionization process in the vicinity of Cooper minima. The present experimental and theoretical study of the angular distributions of Xe 4d3/2 and 4d5/2 photoelectrons demonstrates this effect for the first time. The results clearly imply that relativistic effects are likely to be important for intermediate- Z atoms at most energies
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