9,516 research outputs found

    Emergent Form from Structural Optimisation of the Voronoi Polyhedra Structure

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    In the course of the exploration of computational means in the architectural design process, in order to investigate more complex, adaptive geometries, the Voronoi diagram has recently gained some attention, being a three-dimensional space-filling structure which is modular but not repetitive. The project looks at the Voronoi diagram as a load-bearing structure, and whether it can be useful for structural optimisation. Hereby the edges of the Voronoi polyhedra are regarded as structural members of a statical system, which then is assessed by structural analysis software. Results seem to indicate that the Voronoi approach produces a very specific structural as well as spatial type of order. Through the dislocation of the Voronoi cells, the statical structure becomes more complex through emergent topology changes, and the initially simple spatial system becomes much more complex through emerging adjacencies and interconnections between spaces. The characteristics of the emerging form, however, lie rather in the complexity how shifted spaces and parts are fitted together, than in a radical overall emergent geometry. Spatially as well as a structurally, the form moves from a simple modular repetitive system towards a more complex adaptive one, with interconnected parts which cannot stand alone but rather form an organic whole

    Towards Rapid Parameter Estimation on Gravitational Waves from Compact Binaries using Interpolated Waveforms

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    Accurate parameter estimation of gravitational waves from coalescing compact binary sources is a key requirement for gravitational-wave astronomy. Evaluating the posterior probability density function of the binary's parameters (component masses, sky location, distance, etc.) requires computing millions of waveforms. The computational expense of parameter estimation is dominated by waveform generation and scales linearly with the waveform computational cost. Previous work showed that gravitational waveforms from non-spinning compact binary sources are amenable to a truncated singular value decomposition, which allows them to be reconstructed via interpolation at fixed computational cost. However, the accuracy requirement for parameter estimation is typically higher than for searches, so it is crucial to ascertain that interpolation does not lead to significant errors. Here we provide a proof of principle to show that interpolated waveforms can be used to recover posterior probability density functions with negligible loss in accuracy with respect to non-interpolated waveforms. This technique has the potential to significantly increase the efficiency of parameter estimation.Comment: 7 pages, 2 figure

    Correlation of ERTS multispectral imagery with suspended matter and chlorophyll in lower Chesapeake Bay

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    The feasibility of using multispectral satellite imagery to monitor the characteristics of estuarine waters is being investigated. Preliminary comparisons of MSS imagery with suspended matter concentrations, particle counts, chlorophyll, transmittance and bathymetry have been made. Some visual correlation of radiance with particulates and chlorophyll has been established. Effects of bathymetry are present, and their relation to transmittance and radiance is being investigated. Greatest detail in suspended matter is revealed by MSS band 5. Near-surface suspended sediment load and chlorophyll can be observed in bands 6 and 7. Images received to date have partially defined extent and location of high suspensate concentrations. Net quantity of suspended matter in the lower Bay has been decreasing since the inception of the study, and represents the diminution of turbid flood waters carried into the Bay in late September, 1972. The results so far point to the utility of MSS imagery in monitoring estuarine water character for the assessment of siltation, productivity, and water types

    Redox-Active Nanomaterials For Nanomedicine Applications

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    Nanomedicine utilizes the remarkable properties of nanomaterials for the diagnosis, treatment, and prevention of disease. Many of these nanomaterials have been shown to have robust antioxidative properties, potentially functioning as strong scavengers of reactive oxygen species. Conversely, several nanomaterials have also been shown to promote the generation of reactive oxygen species, which may precipitate the onset of oxidative stress, a state that is thought to contribute to the development of a variety of adverse conditions. As such, the impacts of nanomaterials on biological entities are often associated with and influenced by their specific redox properties. In this review, we overview several classes of nanomaterials that have been or projected to be used across a wide range of biomedical applications, with discussion focusing on their unique redox properties. Nanomaterials examined include iron, cerium, and titanium metal oxide nanoparticles, gold, silver, and selenium nanoparticles, and various nanoscale carbon allotropes such as graphene, carbon nanotubes, fullerenes, and their derivatives/variations. Principal topics of discussion include the chemical mechanisms by which the nanomaterials directly interact with biological entities and the biological cascades that are thus indirectly impacted. Selected case studies highlighting the redox properties of nanomaterials and how they affect biological responses are used to exemplify the biologically-relevant redox mechanisms for each of the described nanomaterials

    Correlation of chlorophyll, suspended matter, and related parameters of waters in the lower Chesapeake Bay area to LANDSAT-1 imagery

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    The author has identified the following significant results. An effort to relate water parameters of the lower Chesapeake Bay area to multispectral scanner images of LANDSAT 1 has shown that some spectral bands can be correlated to water parameters, and has demonstrated the feasibility of synoptic mapping of estuaries by satellite. Bands 5 and 6 were shown to be useful for monitoring total particles. Band 5 showed high correlation with suspended sediment concentration. Attenuation coefficients monitored continuously by ship along three baselines were cross correlated with radiance values on three days. Improved correlations resulted when tidal conditions were taken into consideration. A contouring program was developed to display sediment variation in the lower Chesapeake Bay from the MSS bands

    Endothelin stimulates PDGF secretion in cultured human mesangial cells

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    Endothelin stimulates PDGF secretion in cultured human mesangial cells. Endothelin, a 17-DKa peptide originally described as a potent vasoconstrictor, also stimulates the release of important regulators of glomerular hemodynamics such as atrial natriuretic factor and renin. In the present study we investigated the role of endothelin in the release of another potent vasoconstrictor and mitogen of human mesangial cells, the platelet-derived growth factor. Endothelin stimulated PDGF release at 12 hours and the effect was sustained for 36 hours. This effect was associated with the enhanced induction of mRNAs encoding PDGF A-and B-chain. Endothelin also induced mitogenesis in human mesangial cells which was accompanied by activation of phospholipase C with increased inositol phosphate turnover. These data suggest a mechanism by which endothelin may regulate mesangial cell function in disease states

    Creation and manipulation of Feshbach resonances with radio-frequency radiation

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    We present a simple technique for studying collisions of ultracold atoms in the presence of a magnetic field and radio-frequency radiation (rf). Resonant control of scattering properties can be achieved by using rf to couple a colliding pair of atoms to a bound state. We show, using the example of 6Li, that in some ranges of rf frequency and magnetic field this can be done without giving rise to losses. We also show that halo molecules of large spatial extent require much less rf power than deeply bound states. Another way to exert resonant control is with a set of rf-coupled bound states, linked to the colliding pair through the molecular interactions that give rise to magnetically tunable Feshbach resonances. This was recently demonstrated for 87Rb [Kaufman et al., Phys. Rev. A 80:050701(R), 2009]. We examine the underlying atomic and molecular physics which made this possible. Lastly, we consider the control that may be exerted over atomic collisions by placing atoms in superpositions of Zeeman states, and suggest that it could be useful where small changes in scattering length are required. We suggest other species for which rf and magnetic field control could together provide a useful tuning mechanism.Comment: 21 pages, 8 figures, submitted to New Journal of Physic

    Telecommunications systems design techniques handbook

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    Handbook presents design and analysis of tracking, telemetry, and command functions utilized in these systems with particular emphasis on deep-space telecommunications. Antenna requirements are also discussed. Handbook provides number of tables outlining various performance criteria. Block diagrams and performance charts are also presented

    Rapidly evaluating the compact-binary likelihood function via interpolation

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    Bayesian parameter estimation on gravitational waves from compact-binary coalescences (CBCs) typically requires millions of template waveform computations at different values of the parameters describing the binary. Sampling techniques such as Markov chain Monte Carlo and nested sampling evaluate likelihoods and, hence, compute template waveforms, serially; thus, the total computational time of the analysis scales linearly with that of template generation. Here we address the issue of rapidly computing the likelihood function of CBC sources with nonspinning components. We show how to efficiently compute the continuous likelihood function on the three-dimensional subspace of parameters on which it has a nontrivial dependence—the chirp mass, symmetric mass ratio and coalescence time—via interpolation. Subsequently, sampling this interpolated likelihood function is a significantly cheaper computational process than directly evaluating the likelihood; we report improvements in computational time of two to three orders of magnitude while keeping likelihoods accurate to ≲0.025%. Generating the interpolant of the likelihood function over a significant portion of the CBC mass space is computationally expensive but highly parallelizable, so the wall time can be very small relative to the time of a full parameter-estimation analysis

    Vortices in Spatially Inhomogeneous Superfluids

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    We study vortices in a radially inhomogeneous superfluid, as realized by a trapped degenerate Bose gas in a uniaxially symmetric potential. We show that, in contrast to a homogeneous superfluid, an off-axis vortex corresponds to an anisotropic superflow whose profile strongly depends on the distance to the trap axis. One consequence of this superflow anisotropy is vortex precession about the trap axis in the absence of an imposed rotation. In the complementary regime of a finite prescribed rotation, we compute the minimum-energy vortex density, showing that in the rapid-rotation limit it is extremely uniform, despite a strongly inhomogeneous (nearly) Thomas-Fermi condensate density ρs(r)\rho_s(r). The weak radially-dependent contribution (2lnρs(r)\propto \nabla^2\ln\rho_s(r)) to the vortex distribution, that vanishes with the number of vortices NvN_v as 1Nv\frac{1}{N_v}, arises from the interplay between vortex quantum discretness (namely their inability to faithfully support the imposed rigid-body rotation) and the inhomogeneous superfluid density. This leads to an enhancement of the vortex density at the center of a typical concave trap, a prediction that is in quantitative agreement with recent experiments (cond-mat/0405240). One striking consequence of the inhomogeneous vortex distribution is an azimuthally-directed, radially-shearing superflow.Comment: 22 RevTeX pages, 20 figures, Submitted to PR
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