Analysis of the BEP According to Calculation of Costs & Business Revenues

Bakalářská práce bude zaměřena na finanční analýzu hospodářského střediska v podniku, ve kterém se provádí výzkum a vývoj v projektech financovaných státními dotacemi. Jedná se o středisko výrobního podniku, ve kterém se provádí jak hospodářská činnost (služby, výrobky), tak i výzkum a vývoj podle zákona o podpoře výzkumu a vývoje z veřejných prostředků. V úvodu práce budou stanoveny cíle, které by měly být v závěru práce potvrzeny. Teoretická část práce bude vycházet z dostupné literatury se zaměřením na základní metody a provedení finanční analýzy, kalkulací a bodu zvratu. V praktické části práce bude vycházeno z hodnot zjištěných v účetních výkazech střediska a bude ukázán vliv státních dotací v kalkulacích střediska z hlediska bodu zvratu. V závěru praktické části bude vyhodnocena finanční situace střediska. V závěru práce bude hodnoceno dosažení stanovených cílů práce.The bachelor work will be focused on a financial analysis of a self-contained business (economic) unit in a company in which research & development are performed in projects that are financed by state grants. It is a case of a unit of a manufacturing company, in which both its business activities (services, products) and the R&D are conducted in compliance with the law on support of R&D from public financial resources. The introduction of the work will specify the aims that should be confirmed in the work´s conclusion part. Available literature focusing on basic methods and performance of financial analyses, calculations and the BEP will be the source documents of the theoretical part of the work. The practical part will be based on values found in the accounting documents of the unit and the influence of the state grants as it is reflected in the calculations of the unit will be shown while taking into consideration the BEP aspect. In conclusion of the practical part, financial situation of the unit will be evaluated. In the final part of the work, an assessment of the work`s aims achieved will be presented.

Suggestions for Improvement in Long - Termed Material Property Economy

Diplomová práce je zaměřena na rozbor využití výrobních prostředků a jejich péči ve firmě RAMET C.H.M. a.s. v Kunovicích. V práci je provedena analýza současného stavu majetku, strojů a zařízení používaných při výrobě radiolokačních antén. V rámci péče o majetek jsou uvedeny plánované a neplánované postupy činností údržby a oprav strojů a zařízení. V části návrhů na řešení jsou doporučeny postupy pro udržení výrobních schopností založené na extenzivní analýze vlivu objemu majetku na objem výroby. Je uveden postup pro stanovení spolehlivosti výrobního řetězce při výrobě antén, která souvisí s mezní výrobní schopností a náklady na udržení provozuschopnosti výrobních prostředků.This thesis is focused on analysis of production facilities utilization and maintenance in the company RAMET C.H.M. a.s. located in Kunovice. In this thesis, there is performed the analysis of present property condition, machinery and equipment used within radar antenna production. Within property maintenance, there are introduced planned and unplanned processes of servicing activities and machine and equipment repair. In a part of proposal for solution, there are recommended processes for keeping up production capabilities based on extensive analysis of size property influence on production volume. The method for reliability estimation of production chain is described for the antenna production, related to limiting production capability and costs to maintain service availability of production facilities.

Runway Inspection by RPAS

This article discusses the use of the RPAS for the inspection of the airport operating areas. The paper compares the current process of the inspection of the airport operating areas by the airport staff with the possibilities which are offered by the use of the modern technology RPAS. The following text also describes how to inspect airport operating areas by the RPAS, specific technical possibilities and the applicable technical solutions. Furthermore there are variants of piloting the RPAS, comparing usable equipment, equipment for video recording and the possibility of using thermal imaging camera in the article

Effect of oral administration of green tea extract in various dosage schemes on oxidative stress status of mice in vivo

Green tea is a favorite beverage and its extracts are popular components of dietary supplements. The aim of the present in vivo study was to obtain detailed information about the effect of a standard green tea extract (Polyphenon, P), at different doses, on antioxidant enzymes and oxidative stress markers in murine blood, liver, small and large intestine. In all doses, P improved the oxidative stress status via an increased content of plasmatic SH-groups (by 21–67 %). Regarding antioxidant enzymes in tissues, the low dose of P had the best effect as it elevated the activity of NADPH/quinone reductase in liver and small intestine, thioredoxin reductase in small intestine and hepatic superoxide dismutase. Based on these facts, consumation of green tea seems to be safe and beneficial, while consumption of dietary supplements containing high doses of catechins may disturb oxidative balance by lowering the activity of thioredoxin reductase, glutathione S-transferase, glutathione reductase and superoxide dismutase

Effect of selected catechins on doxorubicin antiproliferative efficacy and hepatotoxicity in vitro

Catechins may influence both desirable and undesirable effects of many drugs. In this study, the in vitro effect of (+)-catechin, (–)-epicatechin, (–)-epigallocatechin, (–)-epicatechingallate, and (–)-epigallocatechingallate (EGCG)on the efficacy of anticancer drug doxorubicin (DOX) was studiedin HCT-8 cancer cells.Rat hepatocytes were used to study the influence of EGCG on DOX hepatotoxicity. Cell proliferation and viability were studied by 3-4,5-dimethylthiazol-2-yl-2,5-diphenyl tetrazolium bromide and neutral red uptake assays. Formation of reactive oxigen species was determined using the dichlorofluorescein assay. All of the studied catechins(1–25 µmol L–1) had no effect on the proliferation of intestinal cancer cells and did not affect the antiproliferative effect of DOX (1–8 µmol L–1) in these cells. Moreover, EGCG at 25 µmol L–1 increased the viability of isolated hepatocytes and significantly protected these cells against DOX-induced toxicity and ROS production. Consumption of EGCG during DOX therapy seems to be safe and beneficial, since EGCG does not decrease DOX anticancer efficacy and could ameliorate DOX hepatotoxicity

Cosmopolitan Species As Models for Ecophysiological Responses to Global Change: The Common Reed \u3cem\u3ePhragmites australis\u3c/em\u3e

Phragmites australis is a cosmopolitan grass and often the dominant species in the ecosystems it inhabits. Due to high intraspecific diversity and phenotypic plasticity, P. australis has an extensive ecological amplitude and a great capacity to acclimate to adverse environmental conditions; it can therefore offer valuable insights into plant responses to global change. Here we review the ecology and ecophysiology of prominent P. australis lineages and their responses to multiple forms of global change. Key findings of our review are that: (1) P. australis lineages are well-adapted to regions of their phylogeographic origin and therefore respond differently to changes in climatic conditions such as temperature or atmospheric CO2; (2) each lineage consists of populations that may occur in geographically different habitats and contain multiple genotypes; (3) the phenotypic plasticity of functional and fitness-related traits of a genotype determine the responses to global change factors; (4) genotypes with high plasticity to environmental drivers may acclimate or even vastly expand their ranges, genotypes of medium plasticity must acclimate or experience range-shifts, and those with low plasticity may face local extinction; (5) responses to ancillary types of global change, like shifting levels of soil salinity, flooding, and drought, are not consistent within lineages and depend on adaptation of individual genotypes. These patterns suggest that the diverse lineages of P. australis will undergo intense selective pressure in the face of global change such that the distributions and interactions of co-occurring lineages, as well as those of genotypes within-lineages, are very likely to be altered. We propose that the strong latitudinal clines within and between P. australis lineages can be a useful tool for predicting plant responses to climate change in general and present a conceptual framework for using P. australis lineages to predict plant responses to global change and its consequences

Cosmopolitan Species as Models for Ecophysiological Responses to Global Change: The Common Reed Phragmites australis

Phragmites australis is a cosmopolitan grass and often the dominant species in the ecosystems it inhabits. Due to high intraspecific diversity and phenotypic plasticity, P. australis has an extensive ecological amplitude and a great capacity to acclimate to adverse environmental conditions; it can therefore offer valuable insights into plant responses to global change. Here we review the ecology and ecophysiology of prominent P. australis lineages and their responses to multiple forms of global change. Key findings of our review are that: (1) P. australis lineages are well-adapted to regions of their phylogeographic origin and therefore respond differently to changes in climatic conditions such as temperature or atmospheric CO2; (2) each lineage consists of populations that may occur in geographically different habitats and contain multiple genotypes; (3) the phenotypic plasticity of functional and fitness-related traits of a genotype determine the responses to global change factors; (4) genotypes with high plasticity to environmental drivers may acclimate or even vastly expand their ranges, genotypes of medium plasticity must acclimate or experience range-shifts, and those with low plasticity may face local extinction; (5) responses to ancillary types of global change, like shifting levels of soil salinity, flooding, and drought, are not consistent within lineages and depend on adaptation of individual genotypes. These patterns suggest that the diverse lineages of P. australis will undergo intense selective pressure in the face of global change such that the distributions and interactions of co-occurring lineages, as well as those of genotypes within-lineages, are very likely to be altered. We propose that the strong latitudinal clines within and between P. australis lineages can be a useful tool for predicting plant responses to climate change in general and present a conceptual framework for using P. australis lineages to predict plant responses to global change and its consequences

Oppression symptoms in chldren's drawings - necessary knowledge for arts and crafts teachers

Práce vychází z myšlenky, že pro učitele výtvarné výchovy je důležitá znalost znaků citové tísně, které lze vysledovat v dětských kresbách. Dětí, žijících ve stresu, je čím dál větší množství, a toto je jedna z cest, jak je objevit a včas jim pomoci. Pokud děti žijí pod vlivem stresu (jsou doma týrány, příliš zatěžovány, cítí nedostatek citové péče apod.), vykazují ve svých kresbách jisté znaky, s nimiž pracují dětští psychologové. Kdyby tato problematika byla vyučována na pedagogických fakultách a organizovaly se kurzy pro vyučující výtvarnou výchovu, mohli by pedagogové včas kontaktovat psychologická pracoviště. Práce analyzuje dostupnou českou psychologickou literaturu a zjišťuje, zda se touto myšlenkou již někdo zabýval, dále představuje publikace, které by se daly využít pro studium učitelů, přichází s návrhy postupu práce v hodinách výtvarné výchovy, shrnuje problematiku CAN (syndrom týraného, zanedbávaného a zneužívanéhodítěte) a přináší alarmující čísla Linky bezpečí. V praktické části učitelky z mateřské a základní školy dokazují, že jsou schopny na varovné znaky v dětských kresbách reagovat.The work proceeds from the idea, that the knowledge of signs of emotional distress which can be found in children's drawings is important of arts and crafts teachers. There is more and more children living under stress and this is one of several possible ways of how to find them and provide them timely help. Children living under the stress (exposed to cruelty, too much demands, lack of emotional care etc.) show certain signs in their drawings and children psychologists can work with it. If this issue is taught in pedagogical faculties and in special lessons for arts and craft teachers, educators would be able to contact psychologists in time. The works is analysing available Czech psychological literature and determines whether someone has already worked with the issue, also introduces publications which might be useful for course of study of teachers, brings proposals of the idea of how to proceed in arts and crafts lessons, summarizes the problematic of CAN (syndrome of maltreated, neglected and abused child) and brings alarming tel. numbers of the Safety line. In the practical part, the teachers from kindergarten and grammar school prove that they are able to react to warning signs in children's drawings.Katedra výtvarné výchovyPedagogická fakultaFaculty of Educatio

Bibliographic data processing in context of scientific work evaluation

Tématem práce je popis celého průběhu zpracování informací o publikačních aktivitách odborných a vědeckých pracovníků a současně všech praktických aspektů, které jej určují a ovlivňují se zvláštním zřetelem na Akademii věd ČR (AV ČR), Univerzitu Karlovu v Praze (UK) a 1. lékařskou fakultu UK v Praze (1. LF UK). Cílem práce je ukázat problematiku jako celek, tj. kompletní algoritmus zpracování od zadání informace o publikované práci do informačního systému instituce přes korektury, zveřejnění bibliografických záznamů na webu, ohlášení záznamů do registrů nadřízených organizací až po evaluační proces (podrobně vysvětleno na příkladu 1. LF UK). Jsou vysvětleny základní pojmy, se kterými se v oblasti zpracování publikačních aktivit a jejich evaluace setkáváme. Pozornost je věnována lidskému faktoru jako jedné z komponent určujících kvalitu výsledného procesu. Závěrem je uveden nástin vývoje, o kterém se v současnosti uvažuje a diskutuje. V úvodu práce je podán stručný historický přehled vývoje bibliografie v obecné rovině, registrující postupný vývoj oborové bibliografie až do dnešní formy bibliografických informačních systémů publikovaných prací. Práce se soustřeďuje především na začátky a postupný vývoj automatizovaného zpracování. Hlavní pozornost byla věnována zpracování dat ve speciálních citačních..

Oppression symptoms in chldren's drawings - necessary knowledge for arts and crafts teachers

The work proceeds from the idea, that the knowledge of signs of emotional distress which can be found in children's drawings is important of arts and crafts teachers. There is more and more children living under stress and this is one of several possible ways of how to find them and provide them timely help. Children living under the stress (exposed to cruelty, too much demands, lack of emotional care etc.) show certain signs in their drawings and children psychologists can work with it. If this issue is taught in pedagogical faculties and in special lessons for arts and craft teachers, educators would be able to contact psychologists in time. The works is analysing available Czech psychological literature and determines whether someone has already worked with the issue, also introduces publications which might be useful for course of study of teachers, brings proposals of the idea of how to proceed in arts and crafts lessons, summarizes the problematic of CAN (syndrome of maltreated, neglected and abused child) and brings alarming tel. numbers of the Safety line. In the practical part, the teachers from kindergarten and grammar school prove that they are able to react to warning signs in children's drawings